{"id":"https://openalex.org/W4415363804","doi":"https://doi.org/10.3389/fbinf.2025.1669237","title":"Fish isoallergens and variants: database compilation, in silico allergenicity prediction challenges, and epitope-based threshold optimization","display_name":"Fish isoallergens and variants: database compilation, in silico allergenicity prediction challenges, and epitope-based threshold optimization","publication_year":2025,"publication_date":"2025-10-20","ids":{"openalex":"https://openalex.org/W4415363804","doi":"https://doi.org/10.3389/fbinf.2025.1669237","pmid":"https://pubmed.ncbi.nlm.nih.gov/41189588"},"language":"en","primary_location":{"id":"doi:10.3389/fbinf.2025.1669237","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1669237","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1669237/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1669237/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015679620","display_name":"Vachiranee Limviphuvadh","orcid":"https://orcid.org/0000-0001-5344-0585"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Vachiranee Limviphuvadh","raw_affiliation_strings":["Biomolecular Sequence To Function Division (BSFD), Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Biomolecular Sequence To Function Division (BSFD), Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045252925","display_name":"Thimo Ruethers","orcid":"https://orcid.org/0000-0002-0856-3452"},"institutions":[{"id":"https://openalex.org/I4210110442","display_name":"James Cook University Singapore","ror":"https://ror.org/01y5z8p89","country_code":"SG","type":"education","lineage":["https://openalex.org/I4210110442"]},{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I86467917","display_name":"James Cook University","ror":"https://ror.org/04gsp2c11","country_code":"AU","type":"education","lineage":["https://openalex.org/I86467917"]}],"countries":["AU","SG"],"is_corresponding":false,"raw_author_name":"Thimo Ruethers","raw_affiliation_strings":["Biomolecular Sequence To Function Division (BSFD), Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","Centre for Sustainable Tropical Fisheries and Aquaculture, College of Science and Engineering, James Cook University, Townsville, QLD, Australia","Molecular Allergy Research Laboratory, College of Science and Engineering, James Cook University, Townsville, QLD, Australia","Tropical Futures Institute, James Cook University, Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Biomolecular Sequence To Function Division (BSFD), Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651"]},{"raw_affiliation_string":"Centre for Sustainable Tropical Fisheries and Aquaculture, College of Science and Engineering, James Cook University, Townsville, QLD, Australia","institution_ids":["https://openalex.org/I86467917"]},{"raw_affiliation_string":"Molecular Allergy Research Laboratory, College of Science and Engineering, James Cook University, Townsville, QLD, Australia","institution_ids":["https://openalex.org/I86467917"]},{"raw_affiliation_string":"Tropical Futures Institute, James Cook University, Singapore, Singapore","institution_ids":["https://openalex.org/I4210110442"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101415930","display_name":"Minh N. Nguyen","orcid":"https://orcid.org/0000-0003-4949-2571"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Minh N. Nguyen","raw_affiliation_strings":["Biomolecular Structure To Mechanism Division (BSMD), Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Biomolecular Structure To Mechanism Division (BSMD), Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006005364","display_name":"Dean R. Jerry","orcid":null},"institutions":[{"id":"https://openalex.org/I4210110442","display_name":"James Cook University Singapore","ror":"https://ror.org/01y5z8p89","country_code":"SG","type":"education","lineage":["https://openalex.org/I4210110442"]},{"id":"https://openalex.org/I86467917","display_name":"James Cook University","ror":"https://ror.org/04gsp2c11","country_code":"AU","type":"education","lineage":["https://openalex.org/I86467917"]}],"countries":["AU","SG"],"is_corresponding":false,"raw_author_name":"Dean R. Jerry","raw_affiliation_strings":["Centre for Sustainable Tropical Fisheries and Aquaculture, College of Science and Engineering, James Cook University, Townsville, QLD, Australia","Tropical Futures Institute, James Cook University, Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Centre for Sustainable Tropical Fisheries and Aquaculture, College of Science and Engineering, James Cook University, Townsville, QLD, Australia","institution_ids":["https://openalex.org/I86467917"]},{"raw_affiliation_string":"Tropical Futures Institute, James Cook University, Singapore, Singapore","institution_ids":["https://openalex.org/I4210110442"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080392361","display_name":"Benjamin Smith","orcid":"https://orcid.org/0000-0003-0651-9420"},"institutions":[{"id":"https://openalex.org/I4210110442","display_name":"James Cook University Singapore","ror":"https://ror.org/01y5z8p89","country_code":"SG","type":"education","lineage":["https://openalex.org/I4210110442"]},{"id":"https://openalex.org/I2801261045","display_name":"Monell Chemical Senses Center","ror":"https://ror.org/01mdfdm06","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2801261045"]}],"countries":["SG","US"],"is_corresponding":false,"raw_author_name":"Benjamin P. C. Smith","raw_affiliation_strings":["Monell Chemical Senses Center, Philadelphia, PA, United States","Tropical Futures Institute, James Cook University, Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Monell Chemical Senses Center, Philadelphia, PA, United States","institution_ids":["https://openalex.org/I2801261045"]},{"raw_affiliation_string":"Tropical Futures Institute, James Cook University, Singapore, Singapore","institution_ids":["https://openalex.org/I4210110442"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100661959","display_name":"Yulan Wang","orcid":"https://orcid.org/0000-0002-2831-8737"},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Yulan Wang","raw_affiliation_strings":["Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113601863","display_name":"Yansong Miao","orcid":null},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Yansong Miao","raw_affiliation_strings":["School of Biological Sciences, Nanyang Technological University, Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"School of Biological Sciences, Nanyang Technological University, Singapore, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035499204","display_name":"Anand Kumar Andiappan","orcid":"https://orcid.org/0000-0002-8442-1544"},"institutions":[{"id":"https://openalex.org/I2800824516","display_name":"Singapore Immunology Network","ror":"https://ror.org/03vmmgg57","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2800824516","https://openalex.org/I2801752549"]},{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Anand Kumar Andiappan","raw_affiliation_strings":["Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I2800824516","https://openalex.org/I115228651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079654252","display_name":"Andreas L. Lopata","orcid":"https://orcid.org/0000-0002-2940-9235"},"institutions":[{"id":"https://openalex.org/I86467917","display_name":"James Cook University","ror":"https://ror.org/04gsp2c11","country_code":"AU","type":"education","lineage":["https://openalex.org/I86467917"]},{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4210110442","display_name":"James Cook University Singapore","ror":"https://ror.org/01y5z8p89","country_code":"SG","type":"education","lineage":["https://openalex.org/I4210110442"]}],"countries":["AU","SG"],"is_corresponding":false,"raw_author_name":"Andreas L. Lopata","raw_affiliation_strings":["Biomolecular Sequence To Function Division (BSFD), Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","Centre for Sustainable Tropical Fisheries and Aquaculture, College of Science and Engineering, James Cook University, Townsville, QLD, Australia","Molecular Allergy Research Laboratory, College of Science and Engineering, James Cook University, Townsville, QLD, Australia","Tropical Futures Institute, James Cook University, Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Biomolecular Sequence To Function Division (BSFD), Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651"]},{"raw_affiliation_string":"Centre for Sustainable Tropical Fisheries and Aquaculture, College of Science and Engineering, James Cook University, Townsville, QLD, Australia","institution_ids":["https://openalex.org/I86467917"]},{"raw_affiliation_string":"Molecular Allergy Research Laboratory, College of Science and Engineering, James Cook University, Townsville, QLD, Australia","institution_ids":["https://openalex.org/I86467917"]},{"raw_affiliation_string":"Tropical Futures Institute, James Cook University, Singapore, Singapore","institution_ids":["https://openalex.org/I4210110442"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019975803","display_name":"Sebastian Maurer\u2010Stroh","orcid":"https://orcid.org/0000-0003-0813-9640"},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Sebastian Maurer-Stroh","raw_affiliation_strings":["Biomolecular Sequence To Function Division (BSFD), Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","Yong Loo Lin School of Medicine and Department of Biological Sciences, National University of Singapore (NUS), Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Biomolecular Sequence To Function Division (BSFD), Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore","institution_ids":["https://openalex.org/I115228651"]},{"raw_affiliation_string":"Yong Loo Lin School of Medicine and Department of Biological Sciences, National University of Singapore (NUS), Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5015679620","https://openalex.org/A5019975803"],"corresponding_institution_ids":["https://openalex.org/I115228651","https://openalex.org/I165932596"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.37438934,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":null,"first_page":"1669237","last_page":"1669237"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12388","display_name":"Identification and Quantification in Food","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9908999800682068,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fish-actinopterygii","display_name":"Fish <Actinopterygii>","score":0.7501999735832214},{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.7365999817848206},{"id":"https://openalex.org/keywords/r-package","display_name":"R package","score":0.4052000045776367},{"id":"https://openalex.org/keywords/epitope","display_name":"Epitope","score":0.3628999888896942},{"id":"https://openalex.org/keywords/threshold-dose","display_name":"Threshold dose","score":0.305400013923645}],"concepts":[{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.7501999735832214},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.7365999817848206},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4950999915599823},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.45419999957084656},{"id":"https://openalex.org/C2984074130","wikidata":"https://www.wikidata.org/wiki/Q73539779","display_name":"R package","level":2,"score":0.4052000045776367},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40149998664855957},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.3628999888896942},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.31850001215934753},{"id":"https://openalex.org/C3018011569","wikidata":"https://www.wikidata.org/wiki/Q108378037","display_name":"Threshold dose","level":2,"score":0.305400013923645},{"id":"https://openalex.org/C202632270","wikidata":"https://www.wikidata.org/wiki/Q7798106","display_name":"Threshold model","level":2,"score":0.290800005197525},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.2892000079154968}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fbinf.2025.1669237","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1669237","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1669237/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:41189588","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41189588","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in bioinformatics","raw_type":null},{"id":"pmh:oai:researchonline.jcu.edu.au:89296","is_oa":true,"landing_page_url":null,"pdf_url":"https://researchonline.jcu.edu.au/89296/1/89296.pdf","source":{"id":"https://openalex.org/S4377196350","display_name":"ResearchOnline - JCU (James Cook University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I86467917","host_organization_name":"James Cook University","host_organization_lineage":["https://openalex.org/I86467917"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:4e093deae1044f0da80b33c5997563f3","is_oa":true,"landing_page_url":"https://doaj.org/article/4e093deae1044f0da80b33c5997563f3","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bioinformatics, Vol 5 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:11389479","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12580176","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fbinf.2025.1669237","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1669237","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1669237/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4415363804.pdf"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1992369492","https://openalex.org/W2015176909","https://openalex.org/W2017519756","https://openalex.org/W2089000221","https://openalex.org/W2151932306","https://openalex.org/W2162870908","https://openalex.org/W2281797260","https://openalex.org/W2515293680","https://openalex.org/W2582761630","https://openalex.org/W2751583588","https://openalex.org/W2770254765","https://openalex.org/W2795753611","https://openalex.org/W2799524357","https://openalex.org/W2805788490","https://openalex.org/W2811481580","https://openalex.org/W2900944399","https://openalex.org/W2911882758","https://openalex.org/W2998934530","https://openalex.org/W3020908849","https://openalex.org/W3082473682","https://openalex.org/W3101256226","https://openalex.org/W3158745071","https://openalex.org/W3186310197","https://openalex.org/W3190260127","https://openalex.org/W3207679175","https://openalex.org/W3215004107","https://openalex.org/W4200254489","https://openalex.org/W4282913866","https://openalex.org/W4367154056","https://openalex.org/W4389980269","https://openalex.org/W4394694796","https://openalex.org/W4399546386","https://openalex.org/W4403230065","https://openalex.org/W4403547791","https://openalex.org/W4404697276","https://openalex.org/W4410300669"],"related_works":[],"abstract_inverted_index":{"This":[0],"study":[1],"enhances":[2],"understanding":[3],"of":[4,25],"fish":[5,10],"allergy":[6],"by":[7],"systematically":[8],"compiling":[9],"isoallergens":[11],"and":[12,14,29],"variants":[13],"integrating":[15],"B-cell":[16],"epitope":[17],"data.":[18],"The":[19],"optimized":[20],"thresholds":[21],"improve":[22],"the":[23],"performance":[24],"allergenicity":[26],"prediction":[27],"tools":[28],"can":[30],"be":[31],"applied":[32],"to":[33],"other":[34],"protein":[35],"families":[36],"in":[37],"future":[38],"studies.":[39]},"counts_by_year":[],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-21T00:00:00"}
