{"id":"https://openalex.org/W4414306340","doi":"https://doi.org/10.3389/fbinf.2025.1644695","title":"BC-predict: mining of signal biomarkers and production of models for early-stage breast cancer subtyping and prognosis","display_name":"BC-predict: mining of signal biomarkers and production of models for early-stage breast cancer subtyping and prognosis","publication_year":2025,"publication_date":"2025-09-18","ids":{"openalex":"https://openalex.org/W4414306340","doi":"https://doi.org/10.3389/fbinf.2025.1644695","pmid":"https://pubmed.ncbi.nlm.nih.gov/41048341"},"language":"en","primary_location":{"id":"doi:10.3389/fbinf.2025.1644695","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1644695","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1644695/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1644695/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007916943","display_name":"Sangeetha Muthamilselvan","orcid":"https://orcid.org/0000-0002-2269-5216"},"institutions":[{"id":"https://openalex.org/I932239252","display_name":"SASTRA University","ror":"https://ror.org/032jk8892","country_code":"IN","type":"education","lineage":["https://openalex.org/I932239252"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sangeetha Muthamilselvan","raw_affiliation_strings":["Systems Computational Biology Lab, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India"],"affiliations":[{"raw_affiliation_string":"Systems Computational Biology Lab, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India","institution_ids":["https://openalex.org/I932239252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016585387","display_name":"Natarajan Vaithilingam","orcid":null},"institutions":[{"id":"https://openalex.org/I2800160768","display_name":"Lincoln County Hospital","ror":"https://ror.org/03p30f964","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800160768","https://openalex.org/I2803040662"]},{"id":"https://openalex.org/I2803040662","display_name":"United Lincolnshire Hospitals NHS Trust","ror":"https://ror.org/0377kyv52","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2803040662"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Natarajan Vaithilingam","raw_affiliation_strings":["Lincoln City Hospital, United Lincolnshire Hospitals, National Health Service, Lincoln, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Lincoln City Hospital, United Lincolnshire Hospitals, National Health Service, Lincoln, United Kingdom","institution_ids":["https://openalex.org/I2803040662","https://openalex.org/I2800160768"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046482216","display_name":"Ashok Palaniappan","orcid":"https://orcid.org/0000-0003-2841-9527"},"institutions":[{"id":"https://openalex.org/I932239252","display_name":"SASTRA University","ror":"https://ror.org/032jk8892","country_code":"IN","type":"education","lineage":["https://openalex.org/I932239252"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Ashok Palaniappan","raw_affiliation_strings":["Systems Computational Biology Lab, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India"],"affiliations":[{"raw_affiliation_string":"Systems Computational Biology Lab, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India","institution_ids":["https://openalex.org/I932239252"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5046482216"],"corresponding_institution_ids":["https://openalex.org/I932239252"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":0.7244,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.74578141,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"5","issue":null,"first_page":"1644695","last_page":"1644695"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/subtyping","display_name":"Subtyping","score":0.9007999897003174},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.6448000073432922},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.44929999113082886},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.4268999993801117},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.3862999975681305}],"concepts":[{"id":"https://openalex.org/C83852419","wikidata":"https://www.wikidata.org/wiki/Q2713292","display_name":"Subtyping","level":2,"score":0.9007999897003174},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6448000073432922},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4771000146865845},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.47589999437332153},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.44929999113082886},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.4268999993801117},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3871000111103058},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3862999975681305},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.383899986743927},{"id":"https://openalex.org/C2778348673","wikidata":"https://www.wikidata.org/wiki/Q739302","display_name":"Production (economics)","level":2,"score":0.3677999973297119},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.33480000495910645},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3059000074863434},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29190000891685486},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.2768999934196472}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fbinf.2025.1644695","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1644695","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1644695/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:41048341","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41048341","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:739c24a2f7134147b963aed358ba024d","is_oa":true,"landing_page_url":"https://doaj.org/article/739c24a2f7134147b963aed358ba024d","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bioinformatics, Vol 5 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:11299171","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12488574","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:12488574","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12488574/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fbinf.2025.1644695","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1644695","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1644695/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4414306340.pdf"},"referenced_works_count":112,"referenced_works":["https://openalex.org/W124785916","https://openalex.org/W1499583342","https://openalex.org/W1831050183","https://openalex.org/W1921136678","https://openalex.org/W1970424980","https://openalex.org/W1972898510","https://openalex.org/W1973012451","https://openalex.org/W1973053090","https://openalex.org/W1987441803","https://openalex.org/W1988055795","https://openalex.org/W2005028301","https://openalex.org/W2005895632","https://openalex.org/W2010348402","https://openalex.org/W2018838463","https://openalex.org/W2032031848","https://openalex.org/W2034299903","https://openalex.org/W2041396419","https://openalex.org/W2041579388","https://openalex.org/W2049843744","https://openalex.org/W2062113330","https://openalex.org/W2070742943","https://openalex.org/W2073612478","https://openalex.org/W2079273314","https://openalex.org/W2098263858","https://openalex.org/W2105932025","https://openalex.org/W2106099291","https://openalex.org/W2111547563","https://openalex.org/W2118258530","https://openalex.org/W2118946507","https://openalex.org/W2119434445","https://openalex.org/W2120456037","https://openalex.org/W2121906867","https://openalex.org/W2122197597","https://openalex.org/W2128920415","https://openalex.org/W2134034024","https://openalex.org/W2134629862","https://openalex.org/W2137526110","https://openalex.org/W2142219561","https://openalex.org/W2146512944","https://openalex.org/W2148143831","https://openalex.org/W2155736495","https://openalex.org/W2156665896","https://openalex.org/W2160450758","https://openalex.org/W2166240615","https://openalex.org/W2169862738","https://openalex.org/W2287902414","https://openalex.org/W2291596654","https://openalex.org/W2296717069","https://openalex.org/W2309067861","https://openalex.org/W2536481229","https://openalex.org/W2550108147","https://openalex.org/W2574305039","https://openalex.org/W2586329273","https://openalex.org/W2596981897","https://openalex.org/W2749613778","https://openalex.org/W2755482838","https://openalex.org/W2759221718","https://openalex.org/W2784062576","https://openalex.org/W2791879663","https://openalex.org/W2795099015","https://openalex.org/W2797347913","https://openalex.org/W2800158081","https://openalex.org/W2900251086","https://openalex.org/W2912271695","https://openalex.org/W2914060790","https://openalex.org/W2937000584","https://openalex.org/W2950607619","https://openalex.org/W2953462471","https://openalex.org/W2968856704","https://openalex.org/W2971055962","https://openalex.org/W2976432085","https://openalex.org/W2990463731","https://openalex.org/W2996427414","https://openalex.org/W2998175747","https://openalex.org/W3005985565","https://openalex.org/W3007713414","https://openalex.org/W3009174700","https://openalex.org/W3014321973","https://openalex.org/W3027021006","https://openalex.org/W3033955601","https://openalex.org/W3034957310","https://openalex.org/W3046704184","https://openalex.org/W3048417086","https://openalex.org/W3091783136","https://openalex.org/W3092994367","https://openalex.org/W3116094557","https://openalex.org/W3116143478","https://openalex.org/W3121122066","https://openalex.org/W3128646645","https://openalex.org/W3128877721","https://openalex.org/W3129163615","https://openalex.org/W3136635219","https://openalex.org/W3164919517","https://openalex.org/W3166385857","https://openalex.org/W3207569082","https://openalex.org/W4200043367","https://openalex.org/W4206283263","https://openalex.org/W4206662285","https://openalex.org/W4210254681","https://openalex.org/W4210856878","https://openalex.org/W4213445053","https://openalex.org/W4225725520","https://openalex.org/W4280586652","https://openalex.org/W4296322703","https://openalex.org/W4296784691","https://openalex.org/W4298621008","https://openalex.org/W4299407402","https://openalex.org/W4378083394","https://openalex.org/W4378087412","https://openalex.org/W4382182799","https://openalex.org/W4386545809","https://openalex.org/W4390946922"],"related_works":[],"abstract_inverted_index":{"Pending":[0],"prospective":[1],"studies,":[2],"we":[3],"have":[4],"translated":[5],"the":[6,12],"models":[7,14],"into":[8],"BC-Predict":[9,37],"that":[10],"forks":[11],"best":[13],"developed":[15],"for":[16,28,41],"each":[17],"problem":[18],"in":[19],"a":[20,25],"unified":[21],"interface":[22],"and":[23],"provides":[24],"complete":[26],"readout":[27],"input":[29],"instances":[30],"of":[31],"expression":[32],"data,":[33],"including":[34],"uncertainty":[35],"estimates.":[36],"is":[38],"freely":[39],"available":[40],"non-commercial":[42],"purposes":[43],"at:":[44],"https://apalania.shinyapps.io/BC-Predict.":[45]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}
