{"id":"https://openalex.org/W4414958842","doi":"https://doi.org/10.3389/fbinf.2025.1629526","title":"Unveiling the impact of interferon genes on the immune microenvironment of triple-negative breast cancer: identification of therapeutic targets","display_name":"Unveiling the impact of interferon genes on the immune microenvironment of triple-negative breast cancer: identification of therapeutic targets","publication_year":2025,"publication_date":"2025-10-08","ids":{"openalex":"https://openalex.org/W4414958842","doi":"https://doi.org/10.3389/fbinf.2025.1629526","pmid":"https://pubmed.ncbi.nlm.nih.gov/41132901"},"language":"en","primary_location":{"id":"doi:10.3389/fbinf.2025.1629526","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1629526","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1629526/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1629526/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100414097","display_name":"Ying Liu","orcid":"https://orcid.org/0000-0001-9385-992X"},"institutions":[{"id":"https://openalex.org/I176834541","display_name":"Guangdong Medical College","ror":"https://ror.org/04k5rxe29","country_code":"CN","type":"education","lineage":["https://openalex.org/I176834541"]},{"id":"https://openalex.org/I190242452","display_name":"Guangdong Pharmaceutical University","ror":"https://ror.org/02vg7mz57","country_code":"CN","type":"education","lineage":["https://openalex.org/I190242452"]},{"id":"https://openalex.org/I4210114608","display_name":"Songshan Lake Materials Laboratory","ror":"https://ror.org/020vtf184","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210114608","https://openalex.org/I4210137180","https://openalex.org/I4210159876"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Liu","raw_affiliation_strings":["Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China","The Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan, China"],"affiliations":[{"raw_affiliation_string":"Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I190242452"]},{"raw_affiliation_string":"The Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I4210114608","https://openalex.org/I176834541"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111061622","display_name":"Jiayi Cai","orcid":"https://orcid.org/0009-0002-3285-2761"},"institutions":[{"id":"https://openalex.org/I190242452","display_name":"Guangdong Pharmaceutical University","ror":"https://ror.org/02vg7mz57","country_code":"CN","type":"education","lineage":["https://openalex.org/I190242452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiayi Cai","raw_affiliation_strings":["Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China"],"affiliations":[{"raw_affiliation_string":"Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I190242452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014489748","display_name":"Aamir Fahira","orcid":"https://orcid.org/0000-0001-5501-6884"},"institutions":[{"id":"https://openalex.org/I190242452","display_name":"Guangdong Pharmaceutical University","ror":"https://ror.org/02vg7mz57","country_code":"CN","type":"education","lineage":["https://openalex.org/I190242452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Aamir Fahira","raw_affiliation_strings":["Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China"],"affiliations":[{"raw_affiliation_string":"Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I190242452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059106502","display_name":"Kai Zhuang","orcid":"https://orcid.org/0000-0003-1724-6210"},"institutions":[{"id":"https://openalex.org/I190242452","display_name":"Guangdong Pharmaceutical University","ror":"https://ror.org/02vg7mz57","country_code":"CN","type":"education","lineage":["https://openalex.org/I190242452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kai Zhuang","raw_affiliation_strings":["Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China"],"affiliations":[{"raw_affiliation_string":"Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I190242452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101421117","display_name":"Jiaojiao Wang","orcid":"https://orcid.org/0000-0002-6624-8717"},"institutions":[{"id":"https://openalex.org/I190242452","display_name":"Guangdong Pharmaceutical University","ror":"https://ror.org/02vg7mz57","country_code":"CN","type":"education","lineage":["https://openalex.org/I190242452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiaojiao Wang","raw_affiliation_strings":["Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China"],"affiliations":[{"raw_affiliation_string":"Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I190242452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100684908","display_name":"Zhang Zhi","orcid":"https://orcid.org/0000-0002-8021-5604"},"institutions":[{"id":"https://openalex.org/I176834541","display_name":"Guangdong Medical College","ror":"https://ror.org/04k5rxe29","country_code":"CN","type":"education","lineage":["https://openalex.org/I176834541"]},{"id":"https://openalex.org/I4210114608","display_name":"Songshan Lake Materials Laboratory","ror":"https://ror.org/020vtf184","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210114608","https://openalex.org/I4210137180","https://openalex.org/I4210159876"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi Zhang","raw_affiliation_strings":["The Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan, China"],"affiliations":[{"raw_affiliation_string":"The Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I4210114608","https://openalex.org/I176834541"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lin Yan","orcid":null},"institutions":[{"id":"https://openalex.org/I176834541","display_name":"Guangdong Medical College","ror":"https://ror.org/04k5rxe29","country_code":"CN","type":"education","lineage":["https://openalex.org/I176834541"]},{"id":"https://openalex.org/I4210122949","display_name":"Dongguan People\u2019s Hospital","ror":"https://ror.org/022s5gm85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210122949"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lin Yan","raw_affiliation_strings":["The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, China"],"affiliations":[{"raw_affiliation_string":"The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I4210122949","https://openalex.org/I176834541"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101728382","display_name":"Yong Liu","orcid":"https://orcid.org/0000-0001-6697-5052"},"institutions":[{"id":"https://openalex.org/I176834541","display_name":"Guangdong Medical College","ror":"https://ror.org/04k5rxe29","country_code":"CN","type":"education","lineage":["https://openalex.org/I176834541"]},{"id":"https://openalex.org/I190242452","display_name":"Guangdong Pharmaceutical University","ror":"https://ror.org/02vg7mz57","country_code":"CN","type":"education","lineage":["https://openalex.org/I190242452"]},{"id":"https://openalex.org/I4210114608","display_name":"Songshan Lake Materials Laboratory","ror":"https://ror.org/020vtf184","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210114608","https://openalex.org/I4210137180","https://openalex.org/I4210159876"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yong Liu","raw_affiliation_strings":["Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China","The Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan, China"],"affiliations":[{"raw_affiliation_string":"Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I190242452"]},{"raw_affiliation_string":"The Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I4210114608","https://openalex.org/I176834541"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024615233","display_name":"Defang Ouyang","orcid":"https://orcid.org/0000-0002-8052-4773"},"institutions":[{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]}],"countries":["MO"],"is_corresponding":true,"raw_author_name":"Defang Ouyang","raw_affiliation_strings":["State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences (ICMS), University of Macau, Macau, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences (ICMS), University of Macau, Macau, China","institution_ids":["https://openalex.org/I204512498"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033081847","display_name":"Zunnan Huang","orcid":"https://orcid.org/0000-0002-5821-703X"},"institutions":[{"id":"https://openalex.org/I176834541","display_name":"Guangdong Medical College","ror":"https://ror.org/04k5rxe29","country_code":"CN","type":"education","lineage":["https://openalex.org/I176834541"]},{"id":"https://openalex.org/I190242452","display_name":"Guangdong Pharmaceutical University","ror":"https://ror.org/02vg7mz57","country_code":"CN","type":"education","lineage":["https://openalex.org/I190242452"]},{"id":"https://openalex.org/I4210114608","display_name":"Songshan Lake Materials Laboratory","ror":"https://ror.org/020vtf184","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366","https://openalex.org/I19820366","https://openalex.org/I4210114608","https://openalex.org/I4210137180","https://openalex.org/I4210159876"]},{"id":"https://openalex.org/I4210122949","display_name":"Dongguan People\u2019s Hospital","ror":"https://ror.org/022s5gm85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210122949"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zunnan Huang","raw_affiliation_strings":["Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China","The Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan, China","The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, China"],"affiliations":[{"raw_affiliation_string":"Guangdong Medical University Key Laboratory of Big Data Mining and Precision Drug Design, Dongguan Key Laboratory of Computer-Aided Drug Design, Guangdong Provincial Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I190242452"]},{"raw_affiliation_string":"The Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I4210114608","https://openalex.org/I176834541"]},{"raw_affiliation_string":"The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, China","institution_ids":["https://openalex.org/I4210122949","https://openalex.org/I176834541"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5024615233","https://openalex.org/A5033081847"],"corresponding_institution_ids":["https://openalex.org/I176834541","https://openalex.org/I190242452","https://openalex.org/I204512498","https://openalex.org/I4210114608","https://openalex.org/I4210122949"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.33704263,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":null,"first_page":"1629526","last_page":"1629526"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6019999980926514},{"id":"https://openalex.org/keywords/interferon","display_name":"Interferon","score":0.598800003528595},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.5827000141143799},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5267000198364258},{"id":"https://openalex.org/keywords/competing-endogenous-rna","display_name":"Competing endogenous RNA","score":0.49869999289512634},{"id":"https://openalex.org/keywords/gene-signature","display_name":"Gene signature","score":0.4932999908924103},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"Carcinogenesis","score":0.4812999963760376},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.4034999907016754}],"concepts":[{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6019999980926514},{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.598800003528595},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5827000141143799},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5267000198364258},{"id":"https://openalex.org/C60365752","wikidata":"https://www.wikidata.org/wiki/Q5156306","display_name":"Competing endogenous RNA","level":5,"score":0.49869999289512634},{"id":"https://openalex.org/C2779733811","wikidata":"https://www.wikidata.org/wiki/Q5531562","display_name":"Gene signature","level":4,"score":0.4932999908924103},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.4812999963760376},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4772999882698059},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4318999946117401},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4124000072479248},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.40369999408721924},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.4034999907016754},{"id":"https://openalex.org/C2779696439","wikidata":"https://www.wikidata.org/wiki/Q7512811","display_name":"Signature (topology)","level":2,"score":0.3910999894142151},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3589000105857849},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3578000068664551},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.33309999108314514},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.3327000141143799},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.32760000228881836},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.3068999946117401},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.3057999908924103},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.30160000920295715},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2888000011444092},{"id":"https://openalex.org/C32300475","wikidata":"https://www.wikidata.org/wiki/Q18027992","display_name":"IRF1","level":4,"score":0.272599995136261},{"id":"https://openalex.org/C3018558359","wikidata":"https://www.wikidata.org/wiki/Q1660157","display_name":"Immune escape","level":3,"score":0.27000001072883606},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.26969999074935913},{"id":"https://openalex.org/C3019359096","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune surveillance","level":3,"score":0.25110000371932983}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fbinf.2025.1629526","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1629526","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1629526/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:41132901","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41132901","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:ac4980e74926489c950f4f800b7f741c","is_oa":true,"landing_page_url":"https://doaj.org/article/ac4980e74926489c950f4f800b7f741c","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bioinformatics, Vol 5 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:11350538","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12542738","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fbinf.2025.1629526","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1629526","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1629526/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4414958842.pdf"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W1834477603","https://openalex.org/W1940241680","https://openalex.org/W1975244773","https://openalex.org/W2010457001","https://openalex.org/W2046387002","https://openalex.org/W2048500586","https://openalex.org/W2049690424","https://openalex.org/W2103196126","https://openalex.org/W2117977572","https://openalex.org/W2122506929","https://openalex.org/W2130410032","https://openalex.org/W2159707944","https://openalex.org/W2226630938","https://openalex.org/W2329659234","https://openalex.org/W2521963431","https://openalex.org/W2564579159","https://openalex.org/W2606495925","https://openalex.org/W2767981580","https://openalex.org/W2773992597","https://openalex.org/W2774323335","https://openalex.org/W2886498337","https://openalex.org/W2900123173","https://openalex.org/W2916009910","https://openalex.org/W2965821518","https://openalex.org/W2966862646","https://openalex.org/W2972959939","https://openalex.org/W2989360185","https://openalex.org/W3005889306","https://openalex.org/W3009409341","https://openalex.org/W3012668557","https://openalex.org/W3014160477","https://openalex.org/W3028523516","https://openalex.org/W3047150668","https://openalex.org/W3112554005","https://openalex.org/W3174830234","https://openalex.org/W3183032333","https://openalex.org/W4207050061","https://openalex.org/W4220749029","https://openalex.org/W4220934494","https://openalex.org/W4223539802","https://openalex.org/W4280539331","https://openalex.org/W4280546244","https://openalex.org/W4290888466","https://openalex.org/W4296665277","https://openalex.org/W4298626057","https://openalex.org/W4309099584","https://openalex.org/W4321275866","https://openalex.org/W4366463229","https://openalex.org/W4379053496","https://openalex.org/W4382788514","https://openalex.org/W4386245905","https://openalex.org/W4393935425","https://openalex.org/W4399164533","https://openalex.org/W4400122514","https://openalex.org/W4400420610","https://openalex.org/W4402304153","https://openalex.org/W4405904863","https://openalex.org/W4407189907","https://openalex.org/W4407870211","https://openalex.org/W4408040500","https://openalex.org/W4408523732","https://openalex.org/W4411352178","https://openalex.org/W4412021737","https://openalex.org/W4412127345"],"related_works":[],"abstract_inverted_index":{"This":[0],"study":[1],"established":[2],"a":[3,7],"prognostic":[4,23],"signature":[5,24],"and":[6,15,25,31,56],"ceRNA":[8,27],"network":[9],"associated":[10],"with":[11],"interferon":[12],"in":[13],"TNBC,":[14],"identified":[16],"five":[17],"key":[18],"regulatory":[19],"axes.":[20],"In":[21],"the":[22,26,44,51],"axes,":[28],"STXBP1,":[29],"RBPMS-AS1,":[30],"FAM198B-AS1":[32],"were":[33],"first":[34],"reported":[35],"as":[36],"potential":[37,45],"biomarkers":[38],"of":[39],"TNBC.":[40],"These":[41],"findings":[42],"have":[43],"to":[46],"provide":[47],"new":[48],"insights":[49],"into":[50],"mechanisms":[52],"driving":[53],"TNBC":[54],"tumorigenesis":[55],"development.":[57]},"counts_by_year":[],"updated_date":"2026-04-16T08:26:57.006410","created_date":"2025-10-10T00:00:00"}
