{"id":"https://openalex.org/W4414364593","doi":"https://doi.org/10.3389/fbinf.2025.1567748","title":"Identification and therapeutic investigation of biomarker genes underpinning hepatocellular carcinoma: an in silico study utilising molecular docking and dynamics simulation","display_name":"Identification and therapeutic investigation of biomarker genes underpinning hepatocellular carcinoma: an in silico study utilising molecular docking and dynamics simulation","publication_year":2025,"publication_date":"2025-09-19","ids":{"openalex":"https://openalex.org/W4414364593","doi":"https://doi.org/10.3389/fbinf.2025.1567748","pmid":"https://pubmed.ncbi.nlm.nih.gov/41048345"},"language":"en","primary_location":{"id":"doi:10.3389/fbinf.2025.1567748","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1567748","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1567748/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1567748/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075821543","display_name":"Japita Ghosh","orcid":"https://orcid.org/0000-0002-5733-5173"},"institutions":[{"id":"https://openalex.org/I132359460","display_name":"University of Burdwan","ror":"https://ror.org/05cyd8v32","country_code":"IN","type":"education","lineage":["https://openalex.org/I132359460"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Jishnu Ghosh","raw_affiliation_strings":["Department of Biotechnology, University of Burdwan, Bardhaman, India"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, University of Burdwan, Bardhaman, India","institution_ids":["https://openalex.org/I132359460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029703041","display_name":"Abdullah M. Alshahrani","orcid":"https://orcid.org/0000-0002-9188-4088"},"institutions":[{"id":"https://openalex.org/I82952536","display_name":"King Khalid University","ror":"https://ror.org/052kwzs30","country_code":"SA","type":"education","lineage":["https://openalex.org/I82952536"]}],"countries":["SA"],"is_corresponding":true,"raw_author_name":"Abdullah M. Alshahrani","raw_affiliation_strings":["Department of Basic Medical Science, College of Applied Medical Sciences, Khamis Mushait Campus, King Khalid University (KKU), Abha, Saudi Arabia"],"affiliations":[{"raw_affiliation_string":"Department of Basic Medical Science, College of Applied Medical Sciences, Khamis Mushait Campus, King Khalid University (KKU), Abha, Saudi Arabia","institution_ids":["https://openalex.org/I82952536"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119681065","display_name":"Aritra Palodhi","orcid":null},"institutions":[{"id":"https://openalex.org/I63346067","display_name":"Maulana Abul Kalam Azad Institute of Asian Studies","ror":"https://ror.org/007j02p07","country_code":"IN","type":"facility","lineage":["https://openalex.org/I63346067"]},{"id":"https://openalex.org/I99601430","display_name":"Maulana Abul Kalam Azad University of Technology, West Bengal","ror":"https://ror.org/030tcae29","country_code":"IN","type":"education","lineage":["https://openalex.org/I99601430"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Aritra Palodhi","raw_affiliation_strings":["Department of Bioinformatics, Maulana Abul Kalam Azad University of Technology, West Bengal, Haringhata, India"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Maulana Abul Kalam Azad University of Technology, West Bengal, Haringhata, India","institution_ids":["https://openalex.org/I99601430","https://openalex.org/I63346067"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Debarghya Bhattacharyya","orcid":null},"institutions":[{"id":"https://openalex.org/I63346067","display_name":"Maulana Abul Kalam Azad Institute of Asian Studies","ror":"https://ror.org/007j02p07","country_code":"IN","type":"facility","lineage":["https://openalex.org/I63346067"]},{"id":"https://openalex.org/I99601430","display_name":"Maulana Abul Kalam Azad University of Technology, West Bengal","ror":"https://ror.org/030tcae29","country_code":"IN","type":"education","lineage":["https://openalex.org/I99601430"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Debarghya Bhattacharyya","raw_affiliation_strings":["Department of Bioinformatics, Maulana Abul Kalam Azad University of Technology, West Bengal, Haringhata, India"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Maulana Abul Kalam Azad University of Technology, West Bengal, Haringhata, India","institution_ids":["https://openalex.org/I99601430","https://openalex.org/I63346067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052597578","display_name":"Subhadip Das","orcid":"https://orcid.org/0000-0001-9030-9471"},"institutions":[{"id":"https://openalex.org/I63346067","display_name":"Maulana Abul Kalam Azad Institute of Asian Studies","ror":"https://ror.org/007j02p07","country_code":"IN","type":"facility","lineage":["https://openalex.org/I63346067"]},{"id":"https://openalex.org/I99601430","display_name":"Maulana Abul Kalam Azad University of Technology, West Bengal","ror":"https://ror.org/030tcae29","country_code":"IN","type":"education","lineage":["https://openalex.org/I99601430"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Subhadip Das","raw_affiliation_strings":["Department of Bioinformatics, Maulana Abul Kalam Azad University of Technology, West Bengal, Haringhata, India"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Maulana Abul Kalam Azad University of Technology, West Bengal, Haringhata, India","institution_ids":["https://openalex.org/I99601430","https://openalex.org/I63346067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110944750","display_name":"Sunil Kanti Mondal","orcid":null},"institutions":[{"id":"https://openalex.org/I132359460","display_name":"University of Burdwan","ror":"https://ror.org/05cyd8v32","country_code":"IN","type":"education","lineage":["https://openalex.org/I132359460"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sunil Kanti Mondal","raw_affiliation_strings":["Department of Biotechnology, University of Burdwan, Bardhaman, India"],"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, University of Burdwan, Bardhaman, India","institution_ids":["https://openalex.org/I132359460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042290681","display_name":"Md Abul Kalam","orcid":"https://orcid.org/0000-0003-4236-8519"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Abul Kalam","raw_affiliation_strings":["Bidhannagar College, Kolkata, West Bengal, India"],"affiliations":[{"raw_affiliation_string":"Bidhannagar College, Kolkata, West Bengal, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002040649","display_name":"S Rehan Ahmad","orcid":"https://orcid.org/0000-0003-0796-5238"},"institutions":[{"id":"https://openalex.org/I2801424531","display_name":"Government of West Bengal","ror":"https://ror.org/044jr0f96","country_code":"IN","type":"government","lineage":["https://openalex.org/I2801424531"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"S. Rehan Ahmad","raw_affiliation_strings":["Hiralal Mazumdar Memorial College for Women, West Bengal State University, Government of West Bengal, Kolkata, West Bengal, India"],"affiliations":[{"raw_affiliation_string":"Hiralal Mazumdar Memorial College for Women, West Bengal State University, Government of West Bengal, Kolkata, West Bengal, India","institution_ids":["https://openalex.org/I2801424531"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019235020","display_name":"Chittabrata Mal","orcid":"https://orcid.org/0000-0001-5802-7474"},"institutions":[{"id":"https://openalex.org/I63346067","display_name":"Maulana Abul Kalam Azad Institute of Asian Studies","ror":"https://ror.org/007j02p07","country_code":"IN","type":"facility","lineage":["https://openalex.org/I63346067"]},{"id":"https://openalex.org/I99601430","display_name":"Maulana Abul Kalam Azad University of Technology, West Bengal","ror":"https://ror.org/030tcae29","country_code":"IN","type":"education","lineage":["https://openalex.org/I99601430"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Chittabrata Mal","raw_affiliation_strings":["Department of Bioinformatics, Maulana Abul Kalam Azad University of Technology, West Bengal, Haringhata, India"],"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Maulana Abul Kalam Azad University of Technology, West Bengal, Haringhata, India","institution_ids":["https://openalex.org/I99601430","https://openalex.org/I63346067"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5002040649","https://openalex.org/A5019235020","https://openalex.org/A5029703041"],"corresponding_institution_ids":["https://openalex.org/I2801424531","https://openalex.org/I63346067","https://openalex.org/I82952536","https://openalex.org/I99601430"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.35068714,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":null,"first_page":"1567748","last_page":"1567748"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13779","display_name":"Cancer Mechanisms and Therapy","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13779","display_name":"Cancer Mechanisms and Therapy","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.993399977684021,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9933000206947327,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.8371000289916992},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6284000277519226},{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.5824999809265137},{"id":"https://openalex.org/keywords/underpinning","display_name":"Underpinning","score":0.43059998750686646},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.41620001196861267},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.3856000006198883},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"Precision medicine","score":0.33660000562667847},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.3271999955177307}],"concepts":[{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.8371000289916992},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6965000033378601},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6284000277519226},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.5824999809265137},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48100000619888306},{"id":"https://openalex.org/C2780871342","wikidata":"https://www.wikidata.org/wiki/Q7883752","display_name":"Underpinning","level":2,"score":0.43059998750686646},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.41620001196861267},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.3856000006198883},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.36390000581741333},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.33660000562667847},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.3271999955177307},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.32120001316070557},{"id":"https://openalex.org/C3019646584","wikidata":"https://www.wikidata.org/wiki/Q2311855","display_name":"Molecular biomarkers","level":2,"score":0.3149999976158142},{"id":"https://openalex.org/C137866125","wikidata":"https://www.wikidata.org/wiki/Q4299308","display_name":"Modelling biological systems","level":3,"score":0.2906000018119812},{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.2874999940395355},{"id":"https://openalex.org/C66782513","wikidata":"https://www.wikidata.org/wiki/Q864601","display_name":"Biomedicine","level":2,"score":0.27810001373291016},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.27790001034736633},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27250000834465027},{"id":"https://openalex.org/C93231420","wikidata":"https://www.wikidata.org/wiki/Q841450","display_name":"Toxicogenomics","level":4,"score":0.271699994802475},{"id":"https://openalex.org/C124535831","wikidata":"https://www.wikidata.org/wiki/Q4915074","display_name":"Biomarker discovery","level":4,"score":0.2630999982357025}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fbinf.2025.1567748","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1567748","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1567748/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:41048345","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41048345","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in bioinformatics","raw_type":null},{"id":"pmh:oai:doaj.org/article:7711f0785d914f3fa180e7f98475d945","is_oa":true,"landing_page_url":"https://doaj.org/article/7711f0785d914f3fa180e7f98475d945","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bioinformatics, Vol 5 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:11301752","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12491263","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:12491263","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12491263/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3389/fbinf.2025.1567748","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2025.1567748","pdf_url":"https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2025.1567748/pdf","source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4414364593.pdf"},"referenced_works_count":92,"referenced_works":["https://openalex.org/W59526888","https://openalex.org/W118179289","https://openalex.org/W301654875","https://openalex.org/W1489237918","https://openalex.org/W1864967712","https://openalex.org/W1969423849","https://openalex.org/W2003494512","https://openalex.org/W2009867031","https://openalex.org/W2014858249","https://openalex.org/W2014946189","https://openalex.org/W2018851752","https://openalex.org/W2019079280","https://openalex.org/W2026976753","https://openalex.org/W2043668344","https://openalex.org/W2044172327","https://openalex.org/W2048239644","https://openalex.org/W2051210555","https://openalex.org/W2068777980","https://openalex.org/W2081492752","https://openalex.org/W2099887488","https://openalex.org/W2103501749","https://openalex.org/W2114520383","https://openalex.org/W2123673510","https://openalex.org/W2125411036","https://openalex.org/W2127322768","https://openalex.org/W2139455421","https://openalex.org/W2147301894","https://openalex.org/W2152630148","https://openalex.org/W2165711991","https://openalex.org/W2317719637","https://openalex.org/W2516611199","https://openalex.org/W2589236205","https://openalex.org/W2592895660","https://openalex.org/W2606142660","https://openalex.org/W2618584271","https://openalex.org/W2797197180","https://openalex.org/W2892113269","https://openalex.org/W2898321218","https://openalex.org/W2901086483","https://openalex.org/W2908514932","https://openalex.org/W2912201468","https://openalex.org/W2914371319","https://openalex.org/W2942084807","https://openalex.org/W2944634887","https://openalex.org/W2965022702","https://openalex.org/W2970196665","https://openalex.org/W2981883063","https://openalex.org/W3019361461","https://openalex.org/W3022950633","https://openalex.org/W3028004908","https://openalex.org/W3033251065","https://openalex.org/W3040511351","https://openalex.org/W3077460447","https://openalex.org/W3092280908","https://openalex.org/W3094348707","https://openalex.org/W3107895035","https://openalex.org/W3109877004","https://openalex.org/W3128683638","https://openalex.org/W3158830501","https://openalex.org/W3160190585","https://openalex.org/W3194221043","https://openalex.org/W3215871153","https://openalex.org/W3216238012","https://openalex.org/W3216888722","https://openalex.org/W4212770653","https://openalex.org/W4223598592","https://openalex.org/W4224210739","https://openalex.org/W4225386201","https://openalex.org/W4226026265","https://openalex.org/W4229872748","https://openalex.org/W4283169283","https://openalex.org/W4283643136","https://openalex.org/W4285806900","https://openalex.org/W4297902614","https://openalex.org/W4303984105","https://openalex.org/W4306832107","https://openalex.org/W4307881321","https://openalex.org/W4310230736","https://openalex.org/W4313487531","https://openalex.org/W4321610320","https://openalex.org/W4380852869","https://openalex.org/W4385462668","https://openalex.org/W4392198542","https://openalex.org/W4393935425","https://openalex.org/W4393936599","https://openalex.org/W4395010444","https://openalex.org/W4401467410","https://openalex.org/W4403616708","https://openalex.org/W4403867190","https://openalex.org/W4406633026","https://openalex.org/W4406805525","https://openalex.org/W4409180339"],"related_works":[],"abstract_inverted_index":{"This":[0],"study":[1],"enhances":[2],"our":[3],"understanding":[4],"of":[5,38],"HCC":[6],"biology":[7],"and":[8,25,35,47],"offers":[9],"new":[10],"insights":[11],"into":[12,29],"drug":[13],"interactions.":[14],"It":[15],"presents":[16],"several":[17],"promising":[18],"biomarkers":[19,41],"for":[20,50],"the":[21,36,39],"early":[22],"diagnosis,":[23],"prognosis,":[24],"therapy.":[26],"Further":[27],"investigation":[28],"CDK1/CKS2":[30],"as":[31],"a":[32],"therapeutic":[33,48],"target":[34],"role":[37],"identified":[40],"could":[42],"contribute":[43],"to":[44],"improved":[45],"diagnostic":[46],"strategies":[49],"HCC.":[51]},"counts_by_year":[],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-09-20T00:00:00"}
