{"id":"https://openalex.org/W4406228799","doi":"https://doi.org/10.3389/fbinf.2024.1332782","title":"Detection of reproducible liver cancer specific ligand-receptor signaling in blood","display_name":"Detection of reproducible liver cancer specific ligand-receptor signaling in blood","publication_year":2025,"publication_date":"2025-01-09","ids":{"openalex":"https://openalex.org/W4406228799","doi":"https://doi.org/10.3389/fbinf.2024.1332782","pmid":"https://pubmed.ncbi.nlm.nih.gov/39850635"},"language":"en","primary_location":{"id":"doi:10.3389/fbinf.2024.1332782","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2024.1332782","pdf_url":null,"source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3389/fbinf.2024.1332782","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025013067","display_name":"Aram Safrastyan","orcid":"https://orcid.org/0000-0003-0325-6549"},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]},{"id":"https://openalex.org/I4210127789","display_name":"Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)","ror":"https://ror.org/039a53269","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210127789"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Aram Safrastyan","raw_affiliation_strings":["Genetics and Epigenetics of Aging, Leibniz Institute on Aging-Fritz Lipmann Institute (FLI), Jena, Germany","RNA Bioinformatics and High Throughput Analysis, Friedrich Schiller University Jena, Jena, Germany"],"affiliations":[{"raw_affiliation_string":"Genetics and Epigenetics of Aging, Leibniz Institute on Aging-Fritz Lipmann Institute (FLI), Jena, Germany","institution_ids":["https://openalex.org/I4210127789"]},{"raw_affiliation_string":"RNA Bioinformatics and High Throughput Analysis, Friedrich Schiller University Jena, Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047811783","display_name":"Damian Wollny","orcid":"https://orcid.org/0000-0003-0562-3226"},"institutions":[{"id":"https://openalex.org/I4210127789","display_name":"Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)","ror":"https://ror.org/039a53269","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210127789"]},{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]},{"id":"https://openalex.org/I4210118560","display_name":"Max Planck Institute for Evolutionary Anthropology","ror":"https://ror.org/02a33b393","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210118560"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Damian Wollny","raw_affiliation_strings":["Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany","Genetics and Epigenetics of Aging, Leibniz Institute on Aging-Fritz Lipmann Institute (FLI), Jena, Germany","RNA Bioinformatics and High Throughput Analysis, Friedrich Schiller University Jena, Jena, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany","institution_ids":["https://openalex.org/I4210118560"]},{"raw_affiliation_string":"Genetics and Epigenetics of Aging, Leibniz Institute on Aging-Fritz Lipmann Institute (FLI), Jena, Germany","institution_ids":["https://openalex.org/I4210127789"]},{"raw_affiliation_string":"RNA Bioinformatics and High Throughput Analysis, Friedrich Schiller University Jena, Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5025013067","https://openalex.org/A5047811783"],"corresponding_institution_ids":["https://openalex.org/I4210118560","https://openalex.org/I4210127789","https://openalex.org/I76198965"],"apc_list":{"value":1900,"currency":"USD","value_usd":1900},"apc_paid":{"value":1900,"currency":"USD","value_usd":1900},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00386983,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"4","issue":null,"first_page":"1332782","last_page":"1332782"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9958999752998352,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autocrine-signalling","display_name":"Autocrine signalling","score":0.7224908471107483},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.57940274477005},{"id":"https://openalex.org/keywords/liver-cancer","display_name":"Liver cancer","score":0.5713193416595459},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5580847263336182},{"id":"https://openalex.org/keywords/hepatocyte","display_name":"Hepatocyte","score":0.5294879078865051},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.4953688383102417},{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.4891853630542755},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4879171550273895},{"id":"https://openalex.org/keywords/liver-cell","display_name":"Liver cell","score":0.48002567887306213},{"id":"https://openalex.org/keywords/cancer-cell","display_name":"Cancer cell","score":0.47891533374786377},{"id":"https://openalex.org/keywords/hepatic-stellate-cell","display_name":"Hepatic stellate cell","score":0.43505024909973145},{"id":"https://openalex.org/keywords/blood-cell","display_name":"Blood cell","score":0.4314068555831909},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.39233070611953735},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.36830031871795654},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.35633423924446106},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.32036951184272766},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.29126113653182983},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.25739964842796326},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.2431868314743042},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.20868229866027832},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.14884865283966064},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.141606867313385},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.1115846037864685},{"id":"https://openalex.org/keywords/in-vitro","display_name":"In vitro","score":0.07262283563613892}],"concepts":[{"id":"https://openalex.org/C128240485","wikidata":"https://www.wikidata.org/wiki/Q786998","display_name":"Autocrine signalling","level":3,"score":0.7224908471107483},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.57940274477005},{"id":"https://openalex.org/C2776231280","wikidata":"https://www.wikidata.org/wiki/Q623031","display_name":"Liver cancer","level":3,"score":0.5713193416595459},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5580847263336182},{"id":"https://openalex.org/C2776200302","wikidata":"https://www.wikidata.org/wiki/Q827450","display_name":"Hepatocyte","level":3,"score":0.5294879078865051},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4953688383102417},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.4891853630542755},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4879171550273895},{"id":"https://openalex.org/C2992672570","wikidata":"https://www.wikidata.org/wiki/Q827450","display_name":"Liver cell","level":2,"score":0.48002567887306213},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.47891533374786377},{"id":"https://openalex.org/C176891718","wikidata":"https://www.wikidata.org/wiki/Q1997459","display_name":"Hepatic stellate cell","level":2,"score":0.43505024909973145},{"id":"https://openalex.org/C2779979121","wikidata":"https://www.wikidata.org/wiki/Q211709","display_name":"Blood cell","level":2,"score":0.4314068555831909},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.39233070611953735},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.36830031871795654},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.35633423924446106},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32036951184272766},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29126113653182983},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.25739964842796326},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2431868314743042},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.20868229866027832},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14884865283966064},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.141606867313385},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1115846037864685},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.07262283563613892}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fbinf.2024.1332782","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2024.1332782","pdf_url":null,"source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39850635","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39850635","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11754192","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11754192","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Front Bioinform","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:0e5cc25b26ce4af5a0b8cf7a7bff6f8d","is_oa":true,"landing_page_url":"https://doaj.org/article/0e5cc25b26ce4af5a0b8cf7a7bff6f8d","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bioinformatics, Vol 4 (2025)","raw_type":"article"},{"id":"pmh:oai:www.db-thueringen.de:dbt_mods_00064465","is_oa":true,"landing_page_url":"https://nbn-resolving.org/urn:nbn:de:gbv:27-dbt-64465-7","pdf_url":null,"source":{"id":"https://openalex.org/S4306400120","display_name":"Common Library Network (Der Gemeinsame Bibliotheksverbund)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210149878","host_organization_name":"Verbundzentrale des GBV","host_organization_lineage":["https://openalex.org/I4210149878"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doc-type:Article"}],"best_oa_location":{"id":"doi:10.3389/fbinf.2024.1332782","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbinf.2024.1332782","pdf_url":null,"source":{"id":"https://openalex.org/S4210219554","display_name":"Frontiers in Bioinformatics","issn_l":"2673-7647","issn":["2673-7647"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7699999809265137,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G446763019","display_name":null,"funder_award_id":"512648189","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W1016059894","https://openalex.org/W1810028515","https://openalex.org/W1973094248","https://openalex.org/W2000730994","https://openalex.org/W2036789909","https://openalex.org/W2038625523","https://openalex.org/W2062386210","https://openalex.org/W2094079572","https://openalex.org/W2107940314","https://openalex.org/W2133521804","https://openalex.org/W2508129332","https://openalex.org/W2607092126","https://openalex.org/W2614986146","https://openalex.org/W2624710378","https://openalex.org/W2782684648","https://openalex.org/W2811009228","https://openalex.org/W2896518632","https://openalex.org/W2899540665","https://openalex.org/W2900958958","https://openalex.org/W2901322776","https://openalex.org/W2907514116","https://openalex.org/W2918023653","https://openalex.org/W2949225171","https://openalex.org/W2952615074","https://openalex.org/W2954673706","https://openalex.org/W2962630610","https://openalex.org/W2974869474","https://openalex.org/W3000890074","https://openalex.org/W3007935255","https://openalex.org/W3012498554","https://openalex.org/W3085788829","https://openalex.org/W3092076936","https://openalex.org/W3101614498","https://openalex.org/W3126257077","https://openalex.org/W3132661792","https://openalex.org/W3132946151","https://openalex.org/W3134691885","https://openalex.org/W3138073470","https://openalex.org/W3141445177","https://openalex.org/W3153517214","https://openalex.org/W3155038581","https://openalex.org/W3164692211","https://openalex.org/W3178440915","https://openalex.org/W3198666770","https://openalex.org/W3213324311","https://openalex.org/W3215717056","https://openalex.org/W4210915535","https://openalex.org/W4220903131","https://openalex.org/W4281483810","https://openalex.org/W4281716326","https://openalex.org/W4285032110","https://openalex.org/W4290072634","https://openalex.org/W4293065133","https://openalex.org/W4318595810","https://openalex.org/W4362632619","https://openalex.org/W4372331648","https://openalex.org/W4378611196","https://openalex.org/W4387369311","https://openalex.org/W4399546757","https://openalex.org/W4399584857"],"related_works":["https://openalex.org/W2417912960","https://openalex.org/W2095959177","https://openalex.org/W3123033141","https://openalex.org/W2419034385","https://openalex.org/W3157506044","https://openalex.org/W2017179498","https://openalex.org/W2460183528","https://openalex.org/W2393672160","https://openalex.org/W4252330808","https://openalex.org/W2607348441"],"abstract_inverted_index":{"Cell-cell":[0],"communication":[1],"mediated":[2],"by":[3],"ligand-receptor":[4],"interactions":[5,124],"(LRI)":[6],"is":[7],"critical":[8],"to":[9,108,145],"coordinating":[10],"diverse":[11],"biological":[12,166],"processes":[13,23],"in":[14,100,115,125,160],"homeostasis":[15],"and":[16,80,89,96,162],"disease.":[17],"Lately,":[18],"our":[19,151],"understanding":[20,167],"of":[21,30,45,56,67,103,118,133,156,168],"these":[22,50],"has":[24],"greatly":[25],"expanded":[26],"through":[27],"the":[28,43,54,65,72,82,101,116,154,165],"inference":[29],"cellular":[31],"communication,":[32],"utilizing":[33],"RNA":[34,59,78],"extracted":[35],"from":[36,61],"bulk":[37],"tissue":[38,47],"or":[39],"individual":[40],"cells.":[41],"Considering":[42],"challenge":[44],"obtaining":[46],"biopsies":[48],"for":[49],"approaches,":[51],"we":[52,70,93],"considered":[53],"potential":[55],"studying":[57],"cell-free":[58,77,169],"obtained":[60],"blood.":[62],"To":[63],"test":[64],"feasibility":[66],"this":[68],"approach,":[69],"used":[71],"BulkSignalR":[73],"algorithm":[74],"across":[75,85],"295":[76],"samples":[79],"compared":[81,107],"LRI":[83],"profiles":[84],"multiple":[86],"cancer":[87,105,127,143],"types":[88],"healthy":[90,109],"donors.":[91,110],"Interestingly,":[92],"detected":[94],"specific":[95],"reproducible":[97],"LRIs":[98,137,159],"particularly":[99],"blood":[102,147,161],"liver":[104,126,135,142,158],"patients":[106],"We":[111],"found":[112],"an":[113],"increase":[114],"magnitude":[117],"hepatocyte":[119,122],"interactions,":[120],"notably":[121],"autocrine":[123],"patients.":[128],"Additionally,":[129],"a":[130,139],"robust":[131],"panel":[132],"30":[134],"cancer-specific":[136],"presents":[138],"bridge":[140],"linking":[141],"pathogenesis":[144],"discernible":[146],"markers.":[148],"In":[149],"summary,":[150],"approach":[152],"shows":[153],"plausibility":[155],"detecting":[157],"builds":[163],"upon":[164],"transcriptomes.":[170]},"counts_by_year":[],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}
