{"id":"https://openalex.org/W4404773777","doi":"https://doi.org/10.3389/fams.2024.1465153","title":"Optimizing microbe-infected mosquito release: a stochastic model for malaria prevention","display_name":"Optimizing microbe-infected mosquito release: a stochastic model for malaria prevention","publication_year":2024,"publication_date":"2024-11-27","ids":{"openalex":"https://openalex.org/W4404773777","doi":"https://doi.org/10.3389/fams.2024.1465153"},"language":"en","primary_location":{"id":"doi:10.3389/fams.2024.1465153","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fams.2024.1465153","pdf_url":null,"source":{"id":"https://openalex.org/S2597085352","display_name":"Frontiers in Applied Mathematics and Statistics","issn_l":"2297-4687","issn":["2297-4687"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Applied Mathematics and Statistics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3389/fams.2024.1465153","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026150542","display_name":"Steeven Belvinos Affognon","orcid":"https://orcid.org/0000-0002-3302-7926"},"institutions":[{"id":"https://openalex.org/I12859529","display_name":"University of Nairobi","ror":"https://ror.org/02y9nww90","country_code":"KE","type":"education","lineage":["https://openalex.org/I12859529"]}],"countries":["KE"],"is_corresponding":false,"raw_author_name":"Steeven Belvinos Affognon","raw_affiliation_strings":["University of Nairobi, Nairobi, Kenya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Nairobi, Nairobi, Kenya","institution_ids":["https://openalex.org/I12859529"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078578869","display_name":"Henri E. Z. Tonnang","orcid":"https://orcid.org/0000-0002-9424-9186"},"institutions":[{"id":"https://openalex.org/I168685008","display_name":"International Centre of Insect Physiology and Ecology","ror":"https://ror.org/03qegss47","country_code":"KE","type":"facility","lineage":["https://openalex.org/I168685008"]}],"countries":["KE"],"is_corresponding":false,"raw_author_name":"Henri E. Z. Tonnang","raw_affiliation_strings":["International Centre of Insect Physiology and Ecology (ICIPE), Nairobi, Kenya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre of Insect Physiology and Ecology (ICIPE), Nairobi, Kenya","institution_ids":["https://openalex.org/I168685008"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070036610","display_name":"Philip Ngare","orcid":null},"institutions":[{"id":"https://openalex.org/I12859529","display_name":"University of Nairobi","ror":"https://ror.org/02y9nww90","country_code":"KE","type":"education","lineage":["https://openalex.org/I12859529"]}],"countries":["KE"],"is_corresponding":false,"raw_author_name":"Philip Ngare","raw_affiliation_strings":["University of Nairobi, Nairobi, Kenya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Nairobi, Nairobi, Kenya","institution_ids":["https://openalex.org/I12859529"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114828238","display_name":"Benard Kipchumba Kiplangat","orcid":null},"institutions":[{"id":"https://openalex.org/I12859529","display_name":"University of Nairobi","ror":"https://ror.org/02y9nww90","country_code":"KE","type":"education","lineage":["https://openalex.org/I12859529"]}],"countries":["KE"],"is_corresponding":false,"raw_author_name":"Benard Kipchumba Kiplangat","raw_affiliation_strings":["University of Nairobi, Nairobi, Kenya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Nairobi, Nairobi, Kenya","institution_ids":["https://openalex.org/I12859529"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015945723","display_name":"Shirley Abelman","orcid":"https://orcid.org/0000-0001-8528-1101"},"institutions":[{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Shirley Abelman","raw_affiliation_strings":["University of the Witwatersrand, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of the Witwatersrand, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081604762","display_name":"Jeremy K. Herren","orcid":"https://orcid.org/0000-0003-2239-7275"},"institutions":[{"id":"https://openalex.org/I168685008","display_name":"International Centre of Insect Physiology and Ecology","ror":"https://ror.org/03qegss47","country_code":"KE","type":"facility","lineage":["https://openalex.org/I168685008"]}],"countries":["KE"],"is_corresponding":false,"raw_author_name":"Jeremy K. Herren","raw_affiliation_strings":["International Centre of Insect Physiology and Ecology (ICIPE), Nairobi, Kenya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Centre of Insect Physiology and Ecology (ICIPE), Nairobi, Kenya","institution_ids":["https://openalex.org/I168685008"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1150,"currency":"USD","value_usd":1150},"apc_paid":{"value":1150,"currency":"USD","value_usd":1150},"fwci":1.4109,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.82044117,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"10","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12134","display_name":"Insect symbiosis and bacterial influences","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12134","display_name":"Insect symbiosis and bacterial influences","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11436","display_name":"Entomopathogenic Microorganisms in Pest Control","score":0.9508000016212463,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malaria","display_name":"Malaria","score":0.8052331805229187},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.5100904107093811},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.41215625405311584},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.20497354865074158}],"concepts":[{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.8052331805229187},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5100904107093811},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41215625405311584},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.20497354865074158}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3389/fams.2024.1465153","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fams.2024.1465153","pdf_url":null,"source":{"id":"https://openalex.org/S2597085352","display_name":"Frontiers in Applied Mathematics and Statistics","issn_l":"2297-4687","issn":["2297-4687"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Applied Mathematics and Statistics","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:5b1dbdeadf074bb8959d05b09c8bf628","is_oa":true,"landing_page_url":"https://doaj.org/article/5b1dbdeadf074bb8959d05b09c8bf628","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Applied Mathematics and Statistics, Vol 10 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fams.2024.1465153","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fams.2024.1465153","pdf_url":null,"source":{"id":"https://openalex.org/S2597085352","display_name":"Frontiers in Applied Mathematics and Statistics","issn_l":"2297-4687","issn":["2297-4687"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Applied Mathematics and Statistics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5400000214576721,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W131268427","https://openalex.org/W211650693","https://openalex.org/W1836565328","https://openalex.org/W1979521727","https://openalex.org/W1982672713","https://openalex.org/W1986775557","https://openalex.org/W2003268306","https://openalex.org/W2013041444","https://openalex.org/W2017054741","https://openalex.org/W2026670356","https://openalex.org/W2057890761","https://openalex.org/W2064454178","https://openalex.org/W2081187491","https://openalex.org/W2085111749","https://openalex.org/W2120174687","https://openalex.org/W2131045169","https://openalex.org/W2144944770","https://openalex.org/W2171659341","https://openalex.org/W2252904607","https://openalex.org/W2316788245","https://openalex.org/W2510683294","https://openalex.org/W2807698378","https://openalex.org/W2900545792","https://openalex.org/W2920979574","https://openalex.org/W2936315711","https://openalex.org/W3021796150","https://openalex.org/W3038089874","https://openalex.org/W3109104305","https://openalex.org/W3117988481","https://openalex.org/W3159624917","https://openalex.org/W3165477802","https://openalex.org/W3214026489","https://openalex.org/W4281640023","https://openalex.org/W4291538878","https://openalex.org/W4367053834","https://openalex.org/W4367396057","https://openalex.org/W4376955209","https://openalex.org/W4381550339","https://openalex.org/W4386365456","https://openalex.org/W4391315666","https://openalex.org/W4392674256","https://openalex.org/W4393500585"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W2013243191","https://openalex.org/W1971568933"],"abstract_inverted_index":{"Malaria":[0],"remains":[1],"a":[2,16,29],"critical":[3],"public":[4,146],"health":[5,147],"challenge":[6],"in":[7,114],"Africa,":[8],"demanding":[9],"innovative":[10],"control":[11,27],"strategies.":[12,37],"This":[13],"study":[14],"introduces":[15],"novel":[17],"approach":[18],"using":[19],"Microsporidia":[20,44,126],"MB":[21,45,127],"-infected":[22],"mosquitoes":[23],"and":[24,94,123],"stochastic":[25],"optimal":[26],"within":[28,47],"L\u00e9vy":[30,58],"process":[31],"framework":[32],"to":[33,42,50,54],"regulate":[34],"mosquito":[35,48,70,135],"release":[36,84],"The":[38,75],"primary":[39],"goal":[40],"is":[41],"optimize":[43],"prevalence":[46],"populations":[49],"disrupt":[51],"Plasmodium":[52],"transmission":[53],"humans.":[55],"By":[56],"incorporating":[57],"noise":[59],"into":[60],"the":[61,66,79,108],"modeling":[62],"process,":[63],"we":[64],"capture":[65],"inherent":[67],"randomness":[68],"of":[69],"dynamics,":[71],"improving":[72],"intervention":[73,100],"accuracy.":[74],"model,":[76],"guided":[77],"by":[78],"Hamilton\u2013Jacobi\u2013Bellman":[80],"(HJB)":[81],"equation,":[82],"optimizes":[83],"protocols":[85],"while":[86],"accounting":[87],"for":[88,110,145],"key":[89],"environmental":[90],"factors":[91],"like":[92],"seasonality":[93],"temperature":[95],"fluctuations.":[96],"Results":[97],"show":[98],"that":[99,133],"success":[101],"depends":[102],"on":[103],"local":[104],"climatic":[105],"conditions,":[106],"underscoring":[107],"need":[109],"flexible,":[111],"region-specific":[112],"strategies":[113],"malaria-endemic":[115],"areas.":[116],"Focus":[117],"regions":[118],"include":[119],"Kenya,":[120],"Ghana,":[121],"Niger,":[122],"Benin,":[124],"where":[125],"has":[128],"been":[129],"confirmed.":[130],"Findings":[131],"suggest":[132],"targeted":[134],"releases":[136],"could":[137],"significantly":[138],"reduce":[139],"malaria":[140],"transmission,":[141],"offering":[142],"valuable":[143],"insights":[144],"efforts.":[148]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}