{"id":"https://openalex.org/W4210343847","doi":"https://doi.org/10.32657/10356/154930","title":"Long non-coding RNA functional annotation : machine learning approaches","display_name":"Long non-coding RNA functional annotation : machine learning approaches","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W4210343847","doi":"https://doi.org/10.32657/10356/154930"},"language":"en","primary_location":{"id":"doi:10.32657/10356/154930","is_oa":true,"landing_page_url":"https://doi.org/10.32657/10356/154930","pdf_url":"https://dr.ntu.edu.sg/bitstream/10356/154930/2/main_thesis.pdf","source":null,"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanyang Technological University","raw_type":"dissertation"},"type":"dissertation","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://dr.ntu.edu.sg/bitstream/10356/154930/2/main_thesis.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075131520","display_name":"Yu Zhang","orcid":"https://orcid.org/0000-0003-4952-8095"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Zhang, Yu","raw_affiliation_strings":["School of Computer Science and Engineering"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5075131520"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9819999933242798,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9769999980926514,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chromatin","display_name":"Chromatin","score":0.6708487868309021},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.615961492061615},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5944611430168152},{"id":"https://openalex.org/keywords/exon","display_name":"Exon","score":0.5797076225280762},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.5278544425964355},{"id":"https://openalex.org/keywords/transcription","display_name":"Transcription (linguistics)","score":0.46432676911354065},{"id":"https://openalex.org/keywords/rna-splicing","display_name":"RNA splicing","score":0.45879173278808594},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.45406338572502136},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.39375922083854675},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.200944185256958}],"concepts":[{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.6708487868309021},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.615961492061615},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5944611430168152},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.5797076225280762},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.5278544425964355},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.46432676911354065},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.45879173278808594},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.45406338572502136},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.39375922083854675},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.200944185256958},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.32657/10356/154930","is_oa":true,"landing_page_url":"https://doi.org/10.32657/10356/154930","pdf_url":"https://dr.ntu.edu.sg/bitstream/10356/154930/2/main_thesis.pdf","source":null,"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanyang Technological University","raw_type":"dissertation"},{"id":"pmh:oai:dr.ntu.edu.sg:10356/154930","is_oa":true,"landing_page_url":"https://hdl.handle.net/10356/154930","pdf_url":null,"source":{"id":"https://openalex.org/S4306402609","display_name":"DR-NTU (Nanyang Technological University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I172675005","host_organization_name":"Nanyang Technological University","host_organization_lineage":["https://openalex.org/I172675005"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis-Doctor of Philosophy"}],"best_oa_location":{"id":"doi:10.32657/10356/154930","is_oa":true,"landing_page_url":"https://doi.org/10.32657/10356/154930","pdf_url":"https://dr.ntu.edu.sg/bitstream/10356/154930/2/main_thesis.pdf","source":null,"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanyang Technological University","raw_type":"dissertation"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4210343847.pdf","grobid_xml":"https://content.openalex.org/works/W4210343847.grobid-xml"},"referenced_works_count":211,"referenced_works":["https://openalex.org/W181368058","https://openalex.org/W297888808","https://openalex.org/W1494484168","https://openalex.org/W1528730016","https://openalex.org/W1535005173","https://openalex.org/W1567701663","https://openalex.org/W1577822803","https://openalex.org/W1759437670","https://openalex.org/W1946086926","https://openalex.org/W1966498224","https://openalex.org/W1967417833","https://openalex.org/W1969451832","https://openalex.org/W1975847255","https://openalex.org/W1979768717","https://openalex.org/W1980069210","https://openalex.org/W1985621639","https://openalex.org/W1988896110","https://openalex.org/W1992212213","https://openalex.org/W1998422171","https://openalex.org/W2000672459","https://openalex.org/W2010231497","https://openalex.org/W2012589963","https://openalex.org/W2014108956","https://openalex.org/W2017435800","https://openalex.org/W2034784092","https://openalex.org/W2046792302","https://openalex.org/W2048194168","https://openalex.org/W2052503008","https://openalex.org/W2056419701","https://openalex.org/W2056593219","https://openalex.org/W2061548680","https://openalex.org/W2065337281","https://openalex.org/W2075320162","https://openalex.org/W2078644058","https://openalex.org/W2079983771","https://openalex.org/W2080052447","https://openalex.org/W2087377443","https://openalex.org/W2088017477","https://openalex.org/W2088296450","https://openalex.org/W2098927868","https://openalex.org/W2108012214","https://openalex.org/W2109458623","https://openalex.org/W2111988174","https://openalex.org/W2112250822","https://openalex.org/W2118258530","https://openalex.org/W2127081697","https://openalex.org/W2127640118","https://openalex.org/W2129375421","https://openalex.org/W2129795133","https://openalex.org/W2135302954","https://openalex.org/W2138370010","https://openalex.org/W2139658526","https://openalex.org/W2141337702","https://openalex.org/W2141451151","https://openalex.org/W2142205294","https://openalex.org/W2144015117","https://openalex.org/W2152623715","https://openalex.org/W2153268494","https://openalex.org/W2154624139","https://openalex.org/W2156125289","https://openalex.org/W2156270929","https://openalex.org/W2161700404","https://openalex.org/W2162417400","https://openalex.org/W2166810745","https://openalex.org/W2167827628","https://openalex.org/W2169416332","https://openalex.org/W2169861237","https://openalex.org/W2170747616","https://openalex.org/W2173732482","https://openalex.org/W2174605830","https://openalex.org/W2177321125","https://openalex.org/W2185236314","https://openalex.org/W2245239316","https://openalex.org/W2278525075","https://openalex.org/W2280316621","https://openalex.org/W2290556776","https://openalex.org/W2388201280","https://openalex.org/W2399707041","https://openalex.org/W2415774299","https://openalex.org/W2462108616","https://openalex.org/W2472711401","https://openalex.org/W2493878338","https://openalex.org/W2507399124","https://openalex.org/W2512299449","https://openalex.org/W2538571252","https://openalex.org/W2540331622","https://openalex.org/W2551929191","https://openalex.org/W2555896787","https://openalex.org/W2557367671","https://openalex.org/W2562878668","https://openalex.org/W2563570294","https://openalex.org/W2570194029","https://openalex.org/W2571489439","https://openalex.org/W2580790464","https://openalex.org/W2584523489","https://openalex.org/W2604975057","https://openalex.org/W2610159395","https://openalex.org/W2610181528","https://openalex.org/W2612076232","https://openalex.org/W2614461365","https://openalex.org/W2615786037","https://openalex.org/W2624274298","https://openalex.org/W2626688982","https://openalex.org/W2733926486","https://openalex.org/W2734798616","https://openalex.org/W2734870195","https://openalex.org/W2735741666","https://openalex.org/W2743636198","https://openalex.org/W2763652018","https://openalex.org/W2765094054","https://openalex.org/W2765241643","https://openalex.org/W2767826728","https://openalex.org/W2771511520","https://openalex.org/W2772832167","https://openalex.org/W2774855547","https://openalex.org/W2776574140","https://openalex.org/W2782521778","https://openalex.org/W2786294422","https://openalex.org/W2794896638","https://openalex.org/W2799820278","https://openalex.org/W2805813857","https://openalex.org/W2806904888","https://openalex.org/W2808086198","https://openalex.org/W2882997339","https://openalex.org/W2883874637","https://openalex.org/W2886900083","https://openalex.org/W2889245200","https://openalex.org/W2891866117","https://openalex.org/W2898598946","https://openalex.org/W2901082097","https://openalex.org/W2902499476","https://openalex.org/W2904230974","https://openalex.org/W2904828342","https://openalex.org/W2907027444","https://openalex.org/W2911561283","https://openalex.org/W2912031480","https://openalex.org/W2914698725","https://openalex.org/W2921199159","https://openalex.org/W2924070408","https://openalex.org/W2928692244","https://openalex.org/W2933099477","https://openalex.org/W2939481835","https://openalex.org/W2941697964","https://openalex.org/W2944319490","https://openalex.org/W2944814365","https://openalex.org/W2947402939","https://openalex.org/W2948726969","https://openalex.org/W2951413354","https://openalex.org/W2954519497","https://openalex.org/W2961398236","https://openalex.org/W2970315054","https://openalex.org/W2984302209","https://openalex.org/W2993820226","https://openalex.org/W2994100438","https://openalex.org/W2995297562","https://openalex.org/W2996885618","https://openalex.org/W2999589659","https://openalex.org/W3000568989","https://openalex.org/W3003415212","https://openalex.org/W3003739334","https://openalex.org/W3003876331","https://openalex.org/W3003920946","https://openalex.org/W3005454931","https://openalex.org/W3013495013","https://openalex.org/W3014454282","https://openalex.org/W3018132922","https://openalex.org/W3024406398","https://openalex.org/W3025946183","https://openalex.org/W3032843171","https://openalex.org/W3036421265","https://openalex.org/W3042358042","https://openalex.org/W3042475334","https://openalex.org/W3043627137","https://openalex.org/W3045879648","https://openalex.org/W3045910546","https://openalex.org/W3090653878","https://openalex.org/W3093314943","https://openalex.org/W3100930093","https://openalex.org/W3113747263","https://openalex.org/W3115880421","https://openalex.org/W3119465258","https://openalex.org/W3124068996","https://openalex.org/W3147833596","https://openalex.org/W3179561651","https://openalex.org/W3179817109","https://openalex.org/W3194220893","https://openalex.org/W4200273574","https://openalex.org/W4247109861","https://openalex.org/W4253162298","https://openalex.org/W4309999671","https://openalex.org/W6607291129","https://openalex.org/W6634617903","https://openalex.org/W6648275475","https://openalex.org/W6672525023","https://openalex.org/W6678965508","https://openalex.org/W6681387118","https://openalex.org/W6684438377","https://openalex.org/W6690541797","https://openalex.org/W6695214302","https://openalex.org/W6728889701","https://openalex.org/W6729533813","https://openalex.org/W6731298883","https://openalex.org/W6733487261","https://openalex.org/W6757828608","https://openalex.org/W6761593949","https://openalex.org/W6770259774","https://openalex.org/W6781248163","https://openalex.org/W6786479588","https://openalex.org/W6902611651","https://openalex.org/W6939935060","https://openalex.org/W7073531415"],"related_works":["https://openalex.org/W2361861616","https://openalex.org/W2352780564","https://openalex.org/W2263699433","https://openalex.org/W2377979023","https://openalex.org/W2951456844","https://openalex.org/W2218034408","https://openalex.org/W2130439870","https://openalex.org/W2151954452","https://openalex.org/W178291922","https://openalex.org/W2000278701"],"abstract_inverted_index":{"Long":[0],"Non-coding":[1],"RNA":[2,9],"(lncRNA)":[3],"is":[4,110],"an":[5],"enormous":[6],"class":[7],"of":[8,48,82,103,107],"molecules":[10],"with":[11],"transcript":[12],"length":[13],"longer":[14],"than":[15],"200":[16],"nucleotides.":[17],"lncRNAs":[18,83],"play":[19],"dominant":[20],"roles":[21,42],"in":[22],"complex":[23],"pathological":[24],"and":[25,28,63,77,93],"physiological":[26],"processes,":[27],"they":[29],"are":[30,50,75],"implicated":[31],"to":[32,35,100,111],"be":[33],"related":[34],"diseases.":[36],"Although":[37],"functional":[38,54,73,115],"studies":[39],"suggest":[40],"significant":[41],"for":[43,71],"lncRNAs,":[44],"only":[45],"a":[46],"few":[47],"them":[49],"well":[51],"characterized.":[52],"lncRNA":[53,61,65,72,114],"annotation":[55,74,116],"mainly":[56],"includes":[57],"two":[58],"parts:":[59],"1)":[60],"annotation,":[62],"2)":[64],"function":[66],"exploration.":[67],"The":[68,105],"biological":[69],"experiments":[70],"costly":[76],"time-intensive.":[78],"Moreover,":[79],"the":[80,86,101,113],"characteristics":[81],"such":[84],"as":[85],"high":[87],"biogenesis":[88],"diversity,":[89],"low":[90,94],"conservation":[91],"levels,":[92],"expression":[95],"levels":[96],"pose":[97],"further":[98],"challenges":[99],"understanding":[102],"lncRNAs.":[104],"goal":[106],"this":[108],"thesis":[109],"explore":[112],"using":[117],"machine":[118],"learning":[119],"approaches.":[120]},"counts_by_year":[],"updated_date":"2026-03-25T13:04:00.132906","created_date":"2025-10-10T00:00:00"}