{"id":"https://openalex.org/W4413040189","doi":"https://doi.org/10.3233/shti250956","title":"Time-Series Bert for Sepsis Detection: Uncovering Patient Trajectories Through Vital Sign Embeddings","display_name":"Time-Series Bert for Sepsis Detection: Uncovering Patient Trajectories Through Vital Sign Embeddings","publication_year":2025,"publication_date":"2025-08-07","ids":{"openalex":"https://openalex.org/W4413040189","doi":"https://doi.org/10.3233/shti250956","pmid":"https://pubmed.ncbi.nlm.nih.gov/40775974"},"language":"en","primary_location":{"id":"doi:10.3233/shti250956","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti250956","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.3233/shti250956","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5118508786","display_name":"Roupen Minassian","orcid":null},"institutions":[{"id":"https://openalex.org/I114017466","display_name":"University of Technology Sydney","ror":"https://ror.org/03f0f6041","country_code":"AU","type":"education","lineage":["https://openalex.org/I114017466"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Roupen Minassian","raw_affiliation_strings":["University of Technology Sydney, Australia"],"affiliations":[{"raw_affiliation_string":"University of Technology Sydney, Australia","institution_ids":["https://openalex.org/I114017466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022976646","display_name":"Meera Radhakrishnan","orcid":"https://orcid.org/0000-0002-9884-1769"},"institutions":[{"id":"https://openalex.org/I114017466","display_name":"University of Technology Sydney","ror":"https://ror.org/03f0f6041","country_code":"AU","type":"education","lineage":["https://openalex.org/I114017466"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Meera Radhakrishnan","raw_affiliation_strings":["University of Technology Sydney, Australia"],"affiliations":[{"raw_affiliation_string":"University of Technology Sydney, Australia","institution_ids":["https://openalex.org/I114017466"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100664130","display_name":"Kun Yu","orcid":"https://orcid.org/0000-0001-5138-6749"},"institutions":[{"id":"https://openalex.org/I114017466","display_name":"University of Technology Sydney","ror":"https://ror.org/03f0f6041","country_code":"AU","type":"education","lineage":["https://openalex.org/I114017466"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Kun Yu","raw_affiliation_strings":["University of Technology Sydney, Australia"],"affiliations":[{"raw_affiliation_string":"University of Technology Sydney, Australia","institution_ids":["https://openalex.org/I114017466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5118508786"],"corresponding_institution_ids":["https://openalex.org/I114017466"],"apc_list":null,"apc_paid":null,"fwci":5.845,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.96196373,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"329","issue":null,"first_page":"830","last_page":"835"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12205","display_name":"Time Series Analysis and Forecasting","score":0.9397000074386597,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12205","display_name":"Time Series Analysis and Forecasting","score":0.9397000074386597,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sign","display_name":"Sign (mathematics)","score":0.7118643522262573},{"id":"https://openalex.org/keywords/series","display_name":"Series (stratigraphy)","score":0.6654173731803894},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6192958950996399},{"id":"https://openalex.org/keywords/vital-signs","display_name":"Vital signs","score":0.6050490140914917},{"id":"https://openalex.org/keywords/sepsis","display_name":"Sepsis","score":0.5976280570030212},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3621680438518524},{"id":"https://openalex.org/keywords/real-time-computing","display_name":"Real-time computing","score":0.3577476143836975},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.27968937158584595},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.16742858290672302},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.09668916463851929},{"id":"https://openalex.org/keywords/surgery","display_name":"Surgery","score":0.09126028418540955},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.07001537084579468},{"id":"https://openalex.org/keywords/paleontology","display_name":"Paleontology","score":0.04456773400306702}],"concepts":[{"id":"https://openalex.org/C139676723","wikidata":"https://www.wikidata.org/wiki/Q1193832","display_name":"Sign (mathematics)","level":2,"score":0.7118643522262573},{"id":"https://openalex.org/C143724316","wikidata":"https://www.wikidata.org/wiki/Q312468","display_name":"Series (stratigraphy)","level":2,"score":0.6654173731803894},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6192958950996399},{"id":"https://openalex.org/C2776890885","wikidata":"https://www.wikidata.org/wiki/Q1067560","display_name":"Vital signs","level":2,"score":0.6050490140914917},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.5976280570030212},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3621680438518524},{"id":"https://openalex.org/C79403827","wikidata":"https://www.wikidata.org/wiki/Q3988","display_name":"Real-time computing","level":1,"score":0.3577476143836975},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27968937158584595},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16742858290672302},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.09668916463851929},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.09126028418540955},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07001537084579468},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.04456773400306702},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003422","descriptor_name":"Critical Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003422","descriptor_name":"Critical Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D055986","descriptor_name":"Vital Signs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055986","descriptor_name":"Vital Signs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055986","descriptor_name":"Vital Signs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.3233/shti250956","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti250956","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},{"id":"pmid:40775974","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40775974","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in health technology and informatics","raw_type":null}],"best_oa_location":{"id":"doi:10.3233/shti250956","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti250956","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"sustainable_development_goals":[{"score":0.5799999833106995,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"},{"score":0.4099999964237213,"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2053514191","https://openalex.org/W30340901","https://openalex.org/W1660746341","https://openalex.org/W4205307318","https://openalex.org/W2162926135","https://openalex.org/W2087901682","https://openalex.org/W4285102294","https://openalex.org/W3948632","https://openalex.org/W2116507356","https://openalex.org/W3005991535"],"abstract_inverted_index":{"This":[0],"study":[1],"adapts":[2],"BERT":[3],"for":[4,88],"vital":[5],"sign":[6],"time-series":[7,87],"analysis":[8],"in":[9,41],"sepsis":[10,90],"detection.":[11],"Using":[12],"MIMIC-III":[13],"data,":[14],"our":[15],"model's":[16],"embeddings":[17],"reveal":[18],"patient":[19,71],"clusters":[20],"that":[21],"partition":[22],"septic":[23],"from":[24,85],"non-septic":[25],"cases":[26],"while":[27],"capturing":[28],"physiological":[29,75],"complexity":[30],"through":[31],"diagnosis":[32],"count":[33],"distributions.":[34],"The":[35],"BERT-based":[36],"classifier":[37],"achieves":[38],"robust":[39],"performance":[40],"both":[42],"Precision-Recall":[43],"Area":[44,59],"Under":[45,60],"Curve":[46,61],"(PR":[47],"AUC),":[48,63],"measuring":[49],"precision":[50],"maintenance":[51],"across":[52],"recall":[53],"thresholds,":[54],"and":[55],"Receiver":[56],"Operating":[57],"Characteristic":[58],"(ROC":[62],"quantifying":[64],"septic/non-septic":[65],"case":[66],"discrimination.":[67],"Unsupervised":[68],"learning":[69],"reveals":[70],"subgroups":[72],"with":[73],"distinct":[74],"profiles,":[76],"highlighting":[77],"transformer":[78],"architectures'":[79],"ability":[80],"to":[81],"extract":[82],"meaningful":[83],"patterns":[84],"medical":[86],"enhanced":[89],"monitoring.":[91]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}