{"id":"https://openalex.org/W4410447695","doi":"https://doi.org/10.3233/shti250563","title":"Sociodemographic Profile of People with Diagnosed Pancreatic Cancer in the UK: Retrospective Sentinel Network Cohort Study","display_name":"Sociodemographic Profile of People with Diagnosed Pancreatic Cancer in the UK: Retrospective Sentinel Network Cohort Study","publication_year":2025,"publication_date":"2025-05-15","ids":{"openalex":"https://openalex.org/W4410447695","doi":"https://doi.org/10.3233/shti250563","pmid":"https://pubmed.ncbi.nlm.nih.gov/40380668"},"language":"en","primary_location":{"id":"doi:10.3233/shti250563","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti250563","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI250563","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI250563","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056940844","display_name":"Claire A. Price","orcid":"https://orcid.org/0000-0003-3060-9821"},"institutions":[{"id":"https://openalex.org/I134421475","display_name":"National Physical Laboratory","ror":"https://ror.org/015w2mp89","country_code":"GB","type":"facility","lineage":["https://openalex.org/I134421475"]},{"id":"https://openalex.org/I28290843","display_name":"University of Surrey","ror":"https://ror.org/00ks66431","country_code":"GB","type":"education","lineage":["https://openalex.org/I28290843"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Claire A. Price","raw_affiliation_strings":["Data Science Department, National Physical Laboratory, Teddington, UK","School of Health Sciences, University of Surrey, Guildford, UK"],"raw_orcid":"https://orcid.org/0000-0003-3060-9821","affiliations":[{"raw_affiliation_string":"Data Science Department, National Physical Laboratory, Teddington, UK","institution_ids":["https://openalex.org/I134421475"]},{"raw_affiliation_string":"School of Health Sciences, University of Surrey, Guildford, UK","institution_ids":["https://openalex.org/I28290843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013014513","display_name":"Freda Mold","orcid":"https://orcid.org/0000-0002-6279-5537"},"institutions":[{"id":"https://openalex.org/I28290843","display_name":"University of Surrey","ror":"https://ror.org/00ks66431","country_code":"GB","type":"education","lineage":["https://openalex.org/I28290843"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Freda Mold","raw_affiliation_strings":["School of Health Sciences, University of Surrey, Guildford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Health Sciences, University of Surrey, Guildford, UK","institution_ids":["https://openalex.org/I28290843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006687609","display_name":"Simon de Lusignan","orcid":"https://orcid.org/0000-0002-8553-2641"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Simon de Lusignan","raw_affiliation_strings":["Nuffield Department of Primary Care Health Sciences, University of Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nuffield Department of Primary Care Health Sciences, University of Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072157603","display_name":"Nadia Smith","orcid":"https://orcid.org/0000-0002-6503-3001"},"institutions":[{"id":"https://openalex.org/I4210146582","display_name":"Royal Surrey NHS Foundation Trust","ror":"https://ror.org/050bd8661","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210146582"]},{"id":"https://openalex.org/I4210146647","display_name":"T\u00dcV S\u00dcD (United Kingdom)","ror":"https://ror.org/049zsmy36","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210115964","https://openalex.org/I4210146647"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nadia A.S. Smith","raw_affiliation_strings":["Royal Surrey NHS Foundation Trust, Scientific Computing, Egerton Road, Guildford, UK","T\u00dcV S\u00dcD UK, Chadwick House, Warrington Road, Warrington, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Surrey NHS Foundation Trust, Scientific Computing, Egerton Road, Guildford, UK","institution_ids":["https://openalex.org/I4210146582"]},{"raw_affiliation_string":"T\u00dcV S\u00dcD UK, Chadwick House, Warrington Road, Warrington, UK","institution_ids":["https://openalex.org/I4210146647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052155666","display_name":"Martyn Winn","orcid":"https://orcid.org/0000-0003-0496-6796"},"institutions":[{"id":"https://openalex.org/I162524378","display_name":"Science and Technology Facilities Council","ror":"https://ror.org/057g20z61","country_code":"GB","type":"government","lineage":["https://openalex.org/I162524378","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Martyn Winn","raw_affiliation_strings":["Scientific Computing Department, Science & Technology Facilities Council, Didcot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scientific Computing Department, Science & Technology Facilities Council, Didcot, UK","institution_ids":["https://openalex.org/I162524378"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087145085","display_name":"Agnieszka Lema\u0144ska","orcid":"https://orcid.org/0000-0003-4849-2430"},"institutions":[{"id":"https://openalex.org/I134421475","display_name":"National Physical Laboratory","ror":"https://ror.org/015w2mp89","country_code":"GB","type":"facility","lineage":["https://openalex.org/I134421475"]},{"id":"https://openalex.org/I28290843","display_name":"University of Surrey","ror":"https://ror.org/00ks66431","country_code":"GB","type":"education","lineage":["https://openalex.org/I28290843"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Agnieszka Lemanska","raw_affiliation_strings":["Data Science Department, National Physical Laboratory, Teddington, UK","School of Health Sciences, University of Surrey, Guildford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Data Science Department, National Physical Laboratory, Teddington, UK","institution_ids":["https://openalex.org/I134421475"]},{"raw_affiliation_string":"School of Health Sciences, University of Surrey, Guildford, UK","institution_ids":["https://openalex.org/I28290843"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.24211909,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"327","issue":null,"first_page":"1115","last_page":"1119"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12708","display_name":"Economic and Financial Impacts of Cancer","score":0.9822999835014343,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11141","display_name":"Childhood Cancer Survivors' Quality of Life","score":0.9635000228881836,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-cancer","display_name":"Pancreatic cancer","score":0.8261988759040833},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.8179515600204468},{"id":"https://openalex.org/keywords/underweight","display_name":"Underweight","score":0.7600901126861572},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.6137024164199829},{"id":"https://openalex.org/keywords/overweight","display_name":"Overweight","score":0.6079854965209961},{"id":"https://openalex.org/keywords/cohort","display_name":"Cohort","score":0.5499958395957947},{"id":"https://openalex.org/keywords/retrospective-cohort-study","display_name":"Retrospective cohort study","score":0.549911379814148},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"Diabetes mellitus","score":0.5287779569625854},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.41824784874916077},{"id":"https://openalex.org/keywords/pediatrics","display_name":"Pediatrics","score":0.3320573568344116},{"id":"https://openalex.org/keywords/obesity","display_name":"Obesity","score":0.31584787368774414}],"concepts":[{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.8261988759040833},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8179515600204468},{"id":"https://openalex.org/C2781121325","wikidata":"https://www.wikidata.org/wiki/Q1146902","display_name":"Underweight","level":4,"score":0.7600901126861572},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6137024164199829},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.6079854965209961},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5499958395957947},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.549911379814148},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5287779569625854},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41824784874916077},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3320573568344116},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.31584787368774414},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000091569","descriptor_name":"Sociodemographic Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000091569","descriptor_name":"Sociodemographic Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D011320","descriptor_name":"Primary Health Care","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D011320","descriptor_name":"Primary Health Care","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012959","descriptor_name":"Socioeconomic Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012959","descriptor_name":"Socioeconomic Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3233/shti250563","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti250563","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI250563","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},{"id":"pmid:40380668","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40380668","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in health technology and informatics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3233/shti250563","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti250563","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI250563","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8799999952316284}],"awards":[],"funders":[{"id":"https://openalex.org/F4320314707","display_name":"Government of the United Kingdom","ror":"https://ror.org/05wnh3t63"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320335277","display_name":"National Physical Laboratory","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410447695.pdf","grobid_xml":"https://content.openalex.org/works/W4410447695.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1897789714","https://openalex.org/W2520113602","https://openalex.org/W130814904","https://openalex.org/W2103497017","https://openalex.org/W2054438685","https://openalex.org/W2911488237","https://openalex.org/W798735226","https://openalex.org/W2166137611","https://openalex.org/W2411918094","https://openalex.org/W1752902896"],"abstract_inverted_index":{"Pancreatic":[0],"cancer":[1,12,143,180],"is":[2,7],"a":[3,94],"devasting":[4],"disease":[5],"which":[6],"an":[8],"increasing":[9],"cause":[10],"of":[11,16,31,44,61,89,98,105,130,154,165,169,176,196],"mortality.":[13],"The":[14,76],"aim":[15],"this":[17,197],"study":[18,39],"was":[19,81,122],"to":[20,55,190],"characterise,":[21],"using":[22],"descriptive":[23],"statistics,":[24],"the":[25,45,106,111,170,182],"sociodemographic,":[26,171],"risk":[27,172,195],"and":[28,86,102,145,159,173,187],"clinical":[29,174],"characteristics":[30,175],"who":[32,177],"develops":[33,178],"pancreatic":[34,74,115,142,179],"cancer.":[35,75,116,198],"This":[36],"retrospective":[37],"cohort":[38],"examined":[40],"data":[41],"from":[42,51],"one":[43],"largest":[46],"UK":[47],"primary":[48,63],"care":[49,64],"databases,":[50],"January":[52],"1st":[53],"2006":[54],"August":[56],"31st":[57],"2020.":[58],"A":[59],"total":[60],"573":[62],"practices":[65],"contributed":[66],"data.":[67],"There":[68],"were":[69,91,126,137,148,156],"9,267":[70],"people":[71,90,99,107,118,131,192],"diagnosed":[72],"with":[73,108,132],"median":[77],"age":[78],"at":[79,141,193],"diagnosis":[80,113,144],"73":[82],"years":[83],"(IQR":[84],"16)":[85],"49.8%":[87],"(4,616)":[88],"female.":[92],"Nearly":[93],"third":[95],"(30.2%,":[96],"2,798)":[97],"had":[100],"diabetes,":[101],"85.8%":[103],"(2,400)":[104],"diabetes":[109,112],"received":[110],"before":[114],"For":[117],"for":[119,184],"whom":[120],"ethnicity":[121],"recorded":[123,134],"94.4%":[124],"(5,979)":[125],"white.":[127],"Under":[128],"half":[129],"BMI":[133],"(41.9%,":[135],"571)":[136],"overweight":[138],"or":[139],"obese":[140],"5.9%":[146],"(80)":[147],"underweight.":[149],"In":[150],"addition,":[151],"12.6%":[152],"(1,168)":[153],"participants":[155],"active":[157],"smokers":[158],"1.4%":[160],"(130)":[161],"exceeded":[162],"recommended":[163],"limits":[164],"alcohol.":[166],"Improved":[167],"characterisation":[168],"highlights":[181],"opportunity":[183],"machine":[185],"learning":[186],"other":[188],"technologies":[189],"flag":[191],"high":[194]},"counts_by_year":[],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}