{"id":"https://openalex.org/W4391229328","doi":"https://doi.org/10.3233/shti230947","title":"Phenotype Systemic Lupus Erythematosus Patients from EPIC Cosmos","display_name":"Phenotype Systemic Lupus Erythematosus Patients from EPIC Cosmos","publication_year":2024,"publication_date":"2024-01-25","ids":{"openalex":"https://openalex.org/W4391229328","doi":"https://doi.org/10.3233/shti230947","pmid":"https://pubmed.ncbi.nlm.nih.gov/38269785"},"language":"en","primary_location":{"id":"doi:10.3233/shti230947","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3233/shti230947","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI230947","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI230947","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013004150","display_name":"Jay S. Patel","orcid":"https://orcid.org/0000-0003-0559-5958"},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jay Patel","raw_affiliation_strings":["Department of Health Services Administration and Policy, College of Public Health Temple University, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Services Administration and Policy, College of Public Health Temple University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066989029","display_name":"Lixia Yao","orcid":"https://orcid.org/0000-0002-5187-6120"},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lixia Yao","raw_affiliation_strings":["Department of Health Services Administration and Policy, College of Public Health Temple University, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Services Administration and Policy, College of Public Health Temple University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088631049","display_name":"Ernest R. Vina","orcid":"https://orcid.org/0000-0001-8135-1731"},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ernest Vina","raw_affiliation_strings":["Division of Rheumatology, Temple University School of Medicine, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Rheumatology, Temple University School of Medicine, PA, USA","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015717769","display_name":"David Fleece","orcid":null},"institutions":[{"id":"https://openalex.org/I4210117083","display_name":"Temple University Hospital","ror":"https://ror.org/028rvnd71","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210117083"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Fleece","raw_affiliation_strings":["Temple University School of Medicine and Temple University Hospital, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Temple University School of Medicine and Temple University Hospital, PA, USA","institution_ids":["https://openalex.org/I4210117083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104929483","display_name":"Jayatilleke Arundathi","orcid":null},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jayatilleke Arundathi","raw_affiliation_strings":["Division of Rheumatology, Temple University School of Medicine, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Rheumatology, Temple University School of Medicine, PA, USA","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059691333","display_name":"Roberto Caricchio","orcid":"https://orcid.org/0000-0002-1379-1118"},"institutions":[{"id":"https://openalex.org/I1303243448","display_name":"UMass Memorial Health Care","ror":"https://ror.org/00pq96s96","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1303243448"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roberto Caricchio","raw_affiliation_strings":["Division of Rheumatology, UMass Memorial Health, Worcester, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Rheumatology, UMass Memorial Health, Worcester, MA, USA","institution_ids":["https://openalex.org/I1303243448"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011747432","display_name":"Huanmei Wu","orcid":"https://orcid.org/0000-0003-0346-6044"},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huanmei Wu","raw_affiliation_strings":["Department of Health Services Administration and Policy, College of Public Health Temple University, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Services Administration and Policy, College of Public Health Temple University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I84392919"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5013004150"],"corresponding_institution_ids":["https://openalex.org/I84392919"],"apc_list":null,"apc_paid":null,"fwci":3.0779,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.89664613,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"310","issue":null,"first_page":"159","last_page":"163"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.7853000164031982,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.7853000164031982,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.6690999865531921,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.63919997215271,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epic","display_name":"EPIC","score":0.7396055459976196},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.7256368398666382},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.46427175402641296},{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"Systemic lupus erythematosus","score":0.4286581873893738},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3100595474243164}],"concepts":[{"id":"https://openalex.org/C115519274","wikidata":"https://www.wikidata.org/wiki/Q267903","display_name":"EPIC","level":2,"score":0.7396055459976196},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7256368398666382},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.46427175402641296},{"id":"https://openalex.org/C2776912625","wikidata":"https://www.wikidata.org/wiki/Q1485","display_name":"Systemic lupus erythematosus","level":3,"score":0.4286581873893738},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3100595474243164},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0},{"id":"https://openalex.org/C124952713","wikidata":"https://www.wikidata.org/wiki/Q8242","display_name":"Literature","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000068598","descriptor_name":"Data Accuracy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000068598","descriptor_name":"Data Accuracy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000068598","descriptor_name":"Data Accuracy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010361","descriptor_name":"Patients","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010361","descriptor_name":"Patients","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010361","descriptor_name":"Patients","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038801","descriptor_name":"International Classification of Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038801","descriptor_name":"International Classification of Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038801","descriptor_name":"International Classification of Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3233/shti230947","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3233/shti230947","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI230947","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},{"id":"pmid:38269785","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38269785","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in health technology and informatics","raw_type":null},{"id":"pmh:oai:scholarshare.temple.edu:20.500.12613/11732","is_oa":false,"landing_page_url":"https://scholarshare.temple.edu/handle/20.500.12613/11732","pdf_url":null,"source":{"id":"https://openalex.org/S4306402624","display_name":"TUScholarShare (Temple University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I84392919","host_organization_name":"Temple University","host_organization_lineage":["https://openalex.org/I84392919"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal article"}],"best_oa_location":{"id":"doi:10.3233/shti230947","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3233/shti230947","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI230947","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6000000238418579}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4391229328.pdf","grobid_xml":"https://content.openalex.org/works/W4391229328.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W2016318369","https://openalex.org/W2130077869","https://openalex.org/W2965565685","https://openalex.org/W3010620429","https://openalex.org/W3025283816","https://openalex.org/W3138036524","https://openalex.org/W3157887920","https://openalex.org/W4225773444"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W2586801360","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W1489783725"],"abstract_inverted_index":{"Systemic":[0],"Lupus":[1],"Erythematosus":[2],"(SLE)":[3],"is":[4,13],"a":[5,89],"widespread":[6],"autoimmune":[7],"disease":[8],"for":[9,35],"which":[10],"early":[11],"diagnosis":[12],"paramount":[14],"in":[15,86],"improving":[16],"clinical":[17,62,69],"outcomes.":[18],"In":[19],"this":[20],"project,":[21],"we":[22],"used":[23],"the":[24,32,42,51,76,92],"de-identified":[25],"patients":[26],"from":[27],"Epic":[28],"Cosmos":[29],"to":[30,49,74],"retrieve":[31],"ICD":[33],"code":[34],"SLE,":[36],"checked":[37],"data":[38,81],"quality":[39],"based":[40],"on":[41,58],"EULAR/ACR":[43],"classification":[44,94],"systems,":[45],"created":[46],"an":[47],"approach":[48],"determine":[50],"SLE":[52],"patients,":[53],"and":[54,61],"performed":[55],"statistical":[56],"analyses":[57],"lab":[59],"tests":[60],"characteristics.":[63],"Our":[64],"preliminary":[65],"results":[66],"showed":[67],"that":[68],"notes":[70],"must":[71],"be":[72],"reviewed":[73],"improve":[75],"completeness,":[77],"as":[78],"structured":[79],"EHR":[80],"fields":[82],"provide":[83],"limited":[84],"information":[85],"determining":[87],"if":[88],"patient":[90],"meets":[91],"established":[93],"criteria.":[95]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-05-25T08:39:21.599409","created_date":"2025-10-10T00:00:00"}