{"id":"https://openalex.org/W4382632318","doi":"https://doi.org/10.3233/shti230469","title":"Use of Real-World Data to Support Adverse Drug Reactions Prevention During ePrescription","display_name":"Use of Real-World Data to Support Adverse Drug Reactions Prevention During ePrescription","publication_year":2023,"publication_date":"2023-06-29","ids":{"openalex":"https://openalex.org/W4382632318","doi":"https://doi.org/10.3233/shti230469","pmid":"https://pubmed.ncbi.nlm.nih.gov/37387003"},"language":"en","primary_location":{"id":"doi:10.3233/shti230469","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti230469","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI230469","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI230469","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008584791","display_name":"Vlasios K. Dimitriadis","orcid":"https://orcid.org/0000-0003-2544-8728"},"institutions":[{"id":"https://openalex.org/I4210134249","display_name":"Centre for Research and Technology Hellas","ror":"https://ror.org/03bndpq63","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210134249"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Vlasios Dimitriadis","raw_affiliation_strings":["Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece"],"raw_orcid":"https://orcid.org/0000-0003-2544-8728","affiliations":[{"raw_affiliation_string":"Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece","institution_ids":["https://openalex.org/I4210134249"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047992148","display_name":"Achilleas Chytas","orcid":"https://orcid.org/0000-0001-8486-011X"},"institutions":[{"id":"https://openalex.org/I4210134249","display_name":"Centre for Research and Technology Hellas","ror":"https://ror.org/03bndpq63","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210134249"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Achilleas Chytas","raw_affiliation_strings":["Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece"],"raw_orcid":"https://orcid.org/0000-0001-8486-011X","affiliations":[{"raw_affiliation_string":"Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece","institution_ids":["https://openalex.org/I4210134249"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019576975","display_name":"Margarita Grammatikopoulou","orcid":"https://orcid.org/0000-0003-1064-9439"},"institutions":[{"id":"https://openalex.org/I4210093649","display_name":"Information Technologies Institute","ror":"https://ror.org/0069akp70","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093649"]},{"id":"https://openalex.org/I4210134249","display_name":"Centre for Research and Technology Hellas","ror":"https://ror.org/03bndpq63","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210134249"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Margarita Grammatikopoulou","raw_affiliation_strings":["Information Technologies Institute, Centre for Research and Technology Hellas, Thessaloniki, Greece"],"raw_orcid":"https://orcid.org/0000-0003-1064-9439","affiliations":[{"raw_affiliation_string":"Information Technologies Institute, Centre for Research and Technology Hellas, Thessaloniki, Greece","institution_ids":["https://openalex.org/I4210093649","https://openalex.org/I4210134249"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061839512","display_name":"George Nikolaidis","orcid":"https://orcid.org/0000-0002-2380-9959"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"George Nikolaidis","raw_affiliation_strings":["Ergobyte SA, Thessaloniki, Greece"],"raw_orcid":"https://orcid.org/0000-0002-2380-9959","affiliations":[{"raw_affiliation_string":"Ergobyte SA, Thessaloniki, Greece","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091980465","display_name":"Jenny Pliatsika","orcid":"https://orcid.org/0000-0002-2584-2541"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jenny Pliatsika","raw_affiliation_strings":["Ergobyte SA, Thessaloniki, Greece"],"raw_orcid":"https://orcid.org/0000-0002-2584-2541","affiliations":[{"raw_affiliation_string":"Ergobyte SA, Thessaloniki, Greece","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091980466","display_name":"Martha Zachariadou","orcid":"https://orcid.org/0000-0001-7469-156X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martha Zachariadou","raw_affiliation_strings":["Ergobyte SA, Thessaloniki, Greece"],"raw_orcid":"https://orcid.org/0000-0001-7469-156X","affiliations":[{"raw_affiliation_string":"Ergobyte SA, Thessaloniki, Greece","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091570867","display_name":"Spiros Nikolopoulos","orcid":"https://orcid.org/0000-0002-1367-5133"},"institutions":[{"id":"https://openalex.org/I4210093649","display_name":"Information Technologies Institute","ror":"https://ror.org/0069akp70","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093649"]},{"id":"https://openalex.org/I4210134249","display_name":"Centre for Research and Technology Hellas","ror":"https://ror.org/03bndpq63","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210134249"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Spiros Nikolopoulos","raw_affiliation_strings":["Information Technologies Institute, Centre for Research and Technology Hellas, Thessaloniki, Greece"],"raw_orcid":"https://orcid.org/0000-0002-1367-5133","affiliations":[{"raw_affiliation_string":"Information Technologies Institute, Centre for Research and Technology Hellas, Thessaloniki, Greece","institution_ids":["https://openalex.org/I4210093649","https://openalex.org/I4210134249"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036029445","display_name":"Pantelis Natsiavas","orcid":"https://orcid.org/0000-0002-4061-9815"},"institutions":[{"id":"https://openalex.org/I4210134249","display_name":"Centre for Research and Technology Hellas","ror":"https://ror.org/03bndpq63","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210134249"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Pantelis Natsiavas","raw_affiliation_strings":["Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece"],"raw_orcid":"https://orcid.org/0000-0002-4061-9815","affiliations":[{"raw_affiliation_string":"Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece","institution_ids":["https://openalex.org/I4210134249"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5008584791"],"corresponding_institution_ids":["https://openalex.org/I4210134249"],"apc_list":null,"apc_paid":null,"fwci":0.2829,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.77916667,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"305","issue":null,"first_page":"226","last_page":"229"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.9211999773979187,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.9211999773979187,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/testbed","display_name":"Testbed","score":0.8251413106918335},{"id":"https://openalex.org/keywords/software-deployment","display_name":"Software deployment","score":0.7010870575904846},{"id":"https://openalex.org/keywords/health-records","display_name":"Health records","score":0.6859062910079956},{"id":"https://openalex.org/keywords/drug-reaction","display_name":"Drug reaction","score":0.5635247826576233},{"id":"https://openalex.org/keywords/raw-data","display_name":"Raw data","score":0.5594719648361206},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.540470540523529},{"id":"https://openalex.org/keywords/clinical-decision-support-system","display_name":"Clinical decision support system","score":0.5309996604919434},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.517551600933075},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4893776774406433},{"id":"https://openalex.org/keywords/decision-support-system","display_name":"Decision support system","score":0.4741846024990082},{"id":"https://openalex.org/keywords/adverse-drug-reaction","display_name":"Adverse drug reaction","score":0.4683622121810913},{"id":"https://openalex.org/keywords/health-data","display_name":"Health data","score":0.4370809495449066},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3909264802932739},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.377765953540802},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.37138932943344116},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.23829200863838196},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.2154732346534729},{"id":"https://openalex.org/keywords/health-care","display_name":"Health care","score":0.1626495122909546},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.15865889191627502},{"id":"https://openalex.org/keywords/software-engineering","display_name":"Software engineering","score":0.11685806512832642}],"concepts":[{"id":"https://openalex.org/C31395832","wikidata":"https://www.wikidata.org/wiki/Q1318674","display_name":"Testbed","level":2,"score":0.8251413106918335},{"id":"https://openalex.org/C105339364","wikidata":"https://www.wikidata.org/wiki/Q2297740","display_name":"Software deployment","level":2,"score":0.7010870575904846},{"id":"https://openalex.org/C3019952477","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Health records","level":3,"score":0.6859062910079956},{"id":"https://openalex.org/C2993432071","wikidata":"https://www.wikidata.org/wiki/Q45959","display_name":"Drug reaction","level":3,"score":0.5635247826576233},{"id":"https://openalex.org/C132964779","wikidata":"https://www.wikidata.org/wiki/Q2110223","display_name":"Raw data","level":2,"score":0.5594719648361206},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.540470540523529},{"id":"https://openalex.org/C63527458","wikidata":"https://www.wikidata.org/wiki/Q5133829","display_name":"Clinical decision support system","level":3,"score":0.5309996604919434},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.517551600933075},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4893776774406433},{"id":"https://openalex.org/C107327155","wikidata":"https://www.wikidata.org/wiki/Q330268","display_name":"Decision support system","level":2,"score":0.4741846024990082},{"id":"https://openalex.org/C2780542314","wikidata":"https://www.wikidata.org/wiki/Q45959","display_name":"Adverse drug reaction","level":3,"score":0.4683622121810913},{"id":"https://openalex.org/C3017977704","wikidata":"https://www.wikidata.org/wiki/Q18745135","display_name":"Health data","level":3,"score":0.4370809495449066},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3909264802932739},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.377765953540802},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.37138932943344116},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23829200863838196},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2154732346534729},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.1626495122909546},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.15865889191627502},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.11685806512832642},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011634","descriptor_name":"Public Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011634","descriptor_name":"Public Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011634","descriptor_name":"Public Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020000","descriptor_name":"Decision Support Systems, Clinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020000","descriptor_name":"Decision Support Systems, Clinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020000","descriptor_name":"Decision Support Systems, Clinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.3233/shti230469","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti230469","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI230469","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},{"id":"pmid:37387003","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37387003","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in health technology and informatics","raw_type":null}],"best_oa_location":{"id":"doi:10.3233/shti230469","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti230469","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI230469","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4382632318.pdf"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W2396881363","https://openalex.org/W2809741215","https://openalex.org/W2886144609","https://openalex.org/W2966194224","https://openalex.org/W3164214534","https://openalex.org/W3199469512","https://openalex.org/W3202649559"],"related_works":["https://openalex.org/W2014723379","https://openalex.org/W2373667733","https://openalex.org/W2994173949","https://openalex.org/W2384569975","https://openalex.org/W2347501567","https://openalex.org/W2352051165","https://openalex.org/W2378247705","https://openalex.org/W2032488286","https://openalex.org/W2072738775","https://openalex.org/W4382632318"],"abstract_inverted_index":{"Adverse":[0],"Drug":[1],"Reactions":[2],"(ADRs)":[3],"are":[4],"a":[5,58,104],"crucial":[6],"public":[7],"health":[8,14],"issue":[9],"due":[10],"to":[11,47,56,77],"the":[12,34,73,84,89,95,101],"significant":[13],"and":[15,40,69],"monetary":[16],"burden":[17],"that":[18],"they":[19,42],"can":[20,32],"impose.":[21],"Real-World":[22],"Data":[23],"(RWD),":[24],"e.g.,":[25],"Electronic":[26],"Health":[27],"Records,":[28],"claims":[29],"data,":[30],"etc.,":[31],"support":[33],"identification":[35],"of":[36,97],"potentially":[37],"unknown":[38],"ADRs":[39],"thus,":[41],"could":[43],"provide":[44],"raw":[45],"data":[46,75],"mine":[48,78],"ADR":[49,65,79],"prevention":[50,66,80],"rules.":[51],"The":[52],"PrescIT":[53],"project":[54],"aims":[55],"create":[57],"Clinical":[59],"Decision":[60],"Support":[61],"System":[62],"(CDSS)":[63],"for":[64],"during":[67],"ePrescription":[68],"uses":[70],"OMOP-CDM":[71,98],"as":[72,103],"main":[74],"model":[76],"rules,":[81],"based":[82],"on":[83],"software":[85],"stack":[86],"provided":[87],"by":[88],"OHDSI":[90],"initiative.":[91],"This":[92],"paper":[93],"presents":[94],"deployment":[96],"infrastructure":[99],"using":[100],"MIMIC-III":[102],"testbed.":[105]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}