{"id":"https://openalex.org/W4281492287","doi":"https://doi.org/10.3233/shti220505","title":"Towards the Improvement of Clinical Guidelines Based on Real World Data","display_name":"Towards the Improvement of Clinical Guidelines Based on Real World Data","publication_year":2022,"publication_date":"2022-05-25","ids":{"openalex":"https://openalex.org/W4281492287","doi":"https://doi.org/10.3233/shti220505","pmid":"https://pubmed.ncbi.nlm.nih.gov/35612126"},"language":"en","primary_location":{"id":"doi:10.3233/shti220505","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti220505","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI220505","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI220505","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065973515","display_name":"Elisa Henke","orcid":"https://orcid.org/0000-0002-5002-2676"},"institutions":[{"id":"https://openalex.org/I78650965","display_name":"TU Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]},{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Elisa Henke","raw_affiliation_strings":["Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universit\u00e4t Dresden, Dresden, Germany"],"affiliations":[{"raw_affiliation_string":"Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I4210162051","https://openalex.org/I78650965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010149968","display_name":"Ines Reinecke","orcid":"https://orcid.org/0000-0003-0154-2867"},"institutions":[{"id":"https://openalex.org/I78650965","display_name":"TU Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]},{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ines Reinecke","raw_affiliation_strings":["Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universit\u00e4t Dresden, Dresden, Germany"],"affiliations":[{"raw_affiliation_string":"Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I4210162051","https://openalex.org/I78650965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047827763","display_name":"Mich\u00e9le Zoch","orcid":"https://orcid.org/0000-0002-5577-7760"},"institutions":[{"id":"https://openalex.org/I78650965","display_name":"TU Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]},{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michele Zoch","raw_affiliation_strings":["Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universit\u00e4t Dresden, Dresden, Germany"],"affiliations":[{"raw_affiliation_string":"Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I4210162051","https://openalex.org/I78650965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072891251","display_name":"Martin Sedlmayr","orcid":"https://orcid.org/0000-0002-9888-8460"},"institutions":[{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]},{"id":"https://openalex.org/I78650965","display_name":"TU Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin Sedlmayr","raw_affiliation_strings":["Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universit\u00e4t Dresden, Dresden, Germany"],"affiliations":[{"raw_affiliation_string":"Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I4210162051","https://openalex.org/I78650965"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077252997","display_name":"Franziska Bathelt","orcid":"https://orcid.org/0000-0002-4139-5489"},"institutions":[{"id":"https://openalex.org/I78650965","display_name":"TU Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]},{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Franziska Bathelt","raw_affiliation_strings":["Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universit\u00e4t Dresden, Dresden, Germany"],"affiliations":[{"raw_affiliation_string":"Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I4210162051","https://openalex.org/I78650965"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5065973515"],"corresponding_institution_ids":["https://openalex.org/I4210162051","https://openalex.org/I78650965"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.18573735,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"294","issue":null,"first_page":"480","last_page":"484"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12664","display_name":"Clinical practice guidelines implementation","score":0.9696999788284302,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12664","display_name":"Clinical practice guidelines implementation","score":0.9696999788284302,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10703","display_name":"Business Process Modeling and Analysis","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/1404","display_name":"Management Information Systems"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9362000226974487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7037841081619263},{"id":"https://openalex.org/keywords/business-process-model-and-notation","display_name":"Business Process Model and Notation","score":0.6205928921699524},{"id":"https://openalex.org/keywords/notation","display_name":"Notation","score":0.5311381220817566},{"id":"https://openalex.org/keywords/observational-study","display_name":"Observational study","score":0.5161114931106567},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.506452202796936},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5027697086334229},{"id":"https://openalex.org/keywords/flexibility","display_name":"Flexibility (engineering)","score":0.49803805351257324},{"id":"https://openalex.org/keywords/transferability","display_name":"Transferability","score":0.47336456179618835},{"id":"https://openalex.org/keywords/software-engineering","display_name":"Software engineering","score":0.44983160495758057},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.4464433491230011},{"id":"https://openalex.org/keywords/general-partnership","display_name":"General partnership","score":0.4179397225379944},{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.4166907072067261},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3897840082645416},{"id":"https://openalex.org/keywords/business-process","display_name":"Business process","score":0.38146910071372986},{"id":"https://openalex.org/keywords/process-management","display_name":"Process management","score":0.37868592143058777},{"id":"https://openalex.org/keywords/business-process-modeling","display_name":"Business process modeling","score":0.2990414500236511},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.229859858751297},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.19076818227767944},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.19075950980186462},{"id":"https://openalex.org/keywords/work-in-process","display_name":"Work in process","score":0.15715846419334412},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1352219581604004},{"id":"https://openalex.org/keywords/operations-management","display_name":"Operations management","score":0.1074097752571106},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.10638365149497986}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7037841081619263},{"id":"https://openalex.org/C179299601","wikidata":"https://www.wikidata.org/wiki/Q1017605","display_name":"Business Process Model and Notation","level":5,"score":0.6205928921699524},{"id":"https://openalex.org/C45357846","wikidata":"https://www.wikidata.org/wiki/Q2001982","display_name":"Notation","level":2,"score":0.5311381220817566},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.5161114931106567},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.506452202796936},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5027697086334229},{"id":"https://openalex.org/C2780598303","wikidata":"https://www.wikidata.org/wiki/Q65921492","display_name":"Flexibility (engineering)","level":2,"score":0.49803805351257324},{"id":"https://openalex.org/C61272859","wikidata":"https://www.wikidata.org/wiki/Q7834031","display_name":"Transferability","level":3,"score":0.47336456179618835},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.44983160495758057},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.4464433491230011},{"id":"https://openalex.org/C71750763","wikidata":"https://www.wikidata.org/wiki/Q646164","display_name":"General partnership","level":2,"score":0.4179397225379944},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.4166907072067261},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3897840082645416},{"id":"https://openalex.org/C85345410","wikidata":"https://www.wikidata.org/wiki/Q851587","display_name":"Business process","level":3,"score":0.38146910071372986},{"id":"https://openalex.org/C195094911","wikidata":"https://www.wikidata.org/wiki/Q14167904","display_name":"Process management","level":1,"score":0.37868592143058777},{"id":"https://openalex.org/C207505557","wikidata":"https://www.wikidata.org/wiki/Q4374012","display_name":"Business process modeling","level":4,"score":0.2990414500236511},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.229859858751297},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.19076818227767944},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.19075950980186462},{"id":"https://openalex.org/C174998907","wikidata":"https://www.wikidata.org/wiki/Q357662","display_name":"Work in process","level":2,"score":0.15715846419334412},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1352219581604004},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.1074097752571106},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10638365149497986},{"id":"https://openalex.org/C10138342","wikidata":"https://www.wikidata.org/wiki/Q43015","display_name":"Finance","level":1,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C94375191","wikidata":"https://www.wikidata.org/wiki/Q11205","display_name":"Arithmetic","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C140331021","wikidata":"https://www.wikidata.org/wiki/Q1868104","display_name":"Logit","level":2,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.3233/shti220505","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti220505","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI220505","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},{"id":"pmid:35612126","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35612126","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in health technology and informatics","raw_type":null}],"best_oa_location":{"id":"doi:10.3233/shti220505","is_oa":true,"landing_page_url":"https://doi.org/10.3233/shti220505","pdf_url":"https://ebooks.iospress.nl/pdf/doi/10.3233/SHTI220505","source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"sustainable_development_goals":[{"score":0.5600000023841858,"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4281492287.pdf","grobid_xml":"https://content.openalex.org/works/W4281492287.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1437651867","https://openalex.org/W1538114895","https://openalex.org/W2031779183","https://openalex.org/W2104030526","https://openalex.org/W2901300060","https://openalex.org/W2917622645","https://openalex.org/W2949944067","https://openalex.org/W2972837016","https://openalex.org/W2995764556","https://openalex.org/W3024869739","https://openalex.org/W3036754614","https://openalex.org/W3191775786","https://openalex.org/W3199469512","https://openalex.org/W6771934945","https://openalex.org/W6801592573"],"related_works":["https://openalex.org/W1588733350","https://openalex.org/W2595515738","https://openalex.org/W3121251068","https://openalex.org/W2403967028","https://openalex.org/W1778671501","https://openalex.org/W1557587181","https://openalex.org/W2904052985","https://openalex.org/W2036913131","https://openalex.org/W2115097704","https://openalex.org/W2009962318"],"abstract_inverted_index":{"Computerized":[0],"clinical":[1,30],"guidelines":[2],"(CCG)":[3],"are":[4],"effective":[5],"instruments":[6],"for":[7],"standardizing,":[8],"monitoring":[9],"and":[10,22,54,95],"optimizing":[11],"medical":[12],"treatment":[13,68],"processes.":[14],"Nevertheless,":[15],"due":[16],"to":[17,46,51,55,66],"barriers":[18],"in":[19,29],"flexibility,":[20],"transferability":[21],"acceptance,":[23],"the":[24,72,88],"widespread":[25],"use":[26,47],"of":[27],"CCG":[28,53],"practice":[31],"is":[32],"not":[33],"yet":[34],"common.":[35],"To":[36],"overcome":[37],"those":[38],"issues,":[39],"we":[40,62],"present":[41],"a":[42,59],"concept":[43],"on":[44,71],"how":[45],"real":[48],"world":[49],"data":[50],"evaluate":[52],"recommend":[56],"improvements.":[57],"As":[58],"first":[60],"result,":[61],"defined":[63],"an":[64],"algorithm":[65],"extract":[67],"processes":[69],"based":[70],"standardized":[73],"Observational":[74],"Medical":[75],"Outcomes":[76],"Partnership":[77],"(OMOP)":[78],"Common":[79],"Data":[80],"Model":[81,94],"as":[82,84],"well":[83],"their":[85],"visualization":[86],"using":[87],"graphical":[89],"modeling":[90],"language":[91],"Business":[92],"Process":[93],"Notation":[96],"(BPMN).":[97]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}