{"id":"https://openalex.org/W1568721544","doi":"https://doi.org/10.3233/kes-2007-11407","title":"Automated recognition of cellular phenotypes by support vector machines with feature reduction","display_name":"Automated recognition of cellular phenotypes by support vector machines with feature reduction","publication_year":2007,"publication_date":"2007-09-18","ids":{"openalex":"https://openalex.org/W1568721544","doi":"https://doi.org/10.3233/kes-2007-11407","mag":"1568721544"},"language":"en","primary_location":{"id":"doi:10.3233/kes-2007-11407","is_oa":false,"landing_page_url":"https://doi.org/10.3233/kes-2007-11407","pdf_url":null,"source":{"id":"https://openalex.org/S133764092","display_name":"International Journal of Knowledge-based and Intelligent Engineering Systems","issn_l":"1327-2314","issn":["1327-2314","1875-8827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Knowledge-based and Intelligent Engineering Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Z. Xia","orcid":null},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Z. Xia","raw_affiliation_strings":["Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China","Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China","institution_ids":["https://openalex.org/I55712492"]},{"raw_affiliation_string":"Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China#TAB#","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032045674","display_name":"Xiao Zhou","orcid":"https://orcid.org/0000-0003-4493-2785"},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"X. Zhou","raw_affiliation_strings":["Harvard University, Harvard Center for Neurodegeneration and Repair, Harvard Medical School and Brigham and Women's Hospital, Harvard Medical School, 220 Longwood Avenue, Goldenson Building 524, Boston, MA 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard University, Harvard Center for Neurodegeneration and Repair, Harvard Medical School and Brigham and Women's Hospital, Harvard Medical School, 220 Longwood Avenue, Goldenson Building 524, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Z. Yin","orcid":null},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Z. Yin","raw_affiliation_strings":["Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China","Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China","institution_ids":["https://openalex.org/I55712492"]},{"raw_affiliation_string":"Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China#TAB#","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103201637","display_name":"Yi Sun","orcid":"https://orcid.org/0000-0002-7348-0231"},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Y. Sun","raw_affiliation_strings":["Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China","(Correspd. Tel.: +86 0571 87952010; E-mail: yxsun@iipc.zju.edu.cn) Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 3100 ...#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China","institution_ids":["https://openalex.org/I55712492"]},{"raw_affiliation_string":"(Correspd. Tel.: +86 0571 87952010; E-mail: yxsun@iipc.zju.edu.cn) Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 3100 ...#TAB#","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015077092","display_name":"Stephen T.C. Wong","orcid":"https://orcid.org/0000-0001-9188-6502"},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S.T.C. Wong","raw_affiliation_strings":["Harvard University, Harvard Center for Neurodegeneration and Repair, Harvard Medical School and Brigham and Women's Hospital, Harvard Medical School, 220 Longwood Avenue, Goldenson Building 524, Boston, MA 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard University, Harvard Center for Neurodegeneration and Repair, Harvard Medical School and Brigham and Women's Hospital, Harvard Medical School, 220 Longwood Avenue, Goldenson Building 524, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082634039","display_name":"Y. Mao","orcid":"https://orcid.org/0000-0003-1242-5949"},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Y. Mao","raw_affiliation_strings":["Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China","Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China","institution_ids":["https://openalex.org/I55712492"]},{"raw_affiliation_string":"Zhejiang University, National Laboratory of Industrial Control Technology, Institute of Industrial Process Control, Hangzhou 310027, P.R. China#TAB#","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1427,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.83431509,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":"4","first_page":"247","last_page":"253"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.6379489302635193},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.6294941902160645},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.6246674656867981},{"id":"https://openalex.org/keywords/reduction","display_name":"Reduction (mathematics)","score":0.6139361262321472},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.5936868190765381},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5334176421165466},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4817540645599365},{"id":"https://openalex.org/keywords/dimensionality-reduction","display_name":"Dimensionality reduction","score":0.43024811148643494},{"id":"https://openalex.org/keywords/vector","display_name":"Vector (molecular biology)","score":0.42830508947372437},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3701538145542145},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2692407965660095},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.17637228965759277},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1342809796333313},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.11111369729042053}],"concepts":[{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.6379489302635193},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.6294941902160645},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.6246674656867981},{"id":"https://openalex.org/C111335779","wikidata":"https://www.wikidata.org/wiki/Q3454686","display_name":"Reduction (mathematics)","level":2,"score":0.6139361262321472},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5936868190765381},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5334176421165466},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4817540645599365},{"id":"https://openalex.org/C70518039","wikidata":"https://www.wikidata.org/wiki/Q16000077","display_name":"Dimensionality reduction","level":2,"score":0.43024811148643494},{"id":"https://openalex.org/C92087593","wikidata":"https://www.wikidata.org/wiki/Q427389","display_name":"Vector (molecular biology)","level":4,"score":0.42830508947372437},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3701538145542145},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2692407965660095},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.17637228965759277},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1342809796333313},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11111369729042053},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3233/kes-2007-11407","is_oa":false,"landing_page_url":"https://doi.org/10.3233/kes-2007-11407","pdf_url":null,"source":{"id":"https://openalex.org/S133764092","display_name":"International Journal of Knowledge-based and Intelligent Engineering Systems","issn_l":"1327-2314","issn":["1327-2314","1875-8827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Knowledge-based and Intelligent Engineering Systems","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.41999998688697815,"id":"https://metadata.un.org/sdg/2"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W740415","https://openalex.org/W150916163","https://openalex.org/W1564419782","https://openalex.org/W1984643873","https://openalex.org/W1993669821","https://openalex.org/W2066944227","https://openalex.org/W2086936614","https://openalex.org/W2101355808","https://openalex.org/W2109126584","https://openalex.org/W2116633773","https://openalex.org/W2143426320","https://openalex.org/W2145752049","https://openalex.org/W2156909104","https://openalex.org/W2162686456"],"related_works":["https://openalex.org/W3176621072","https://openalex.org/W2090763504","https://openalex.org/W148178222","https://openalex.org/W1948992892","https://openalex.org/W2104657898","https://openalex.org/W1886884218","https://openalex.org/W1910826599","https://openalex.org/W1980100242","https://openalex.org/W2530420969","https://openalex.org/W2051187167"],"abstract_inverted_index":{"In":[0],"this":[1],"paper,":[2],"wrapper":[3],"based":[4],"feature":[5,26],"selection":[6],"by":[7],"support":[8],"vector":[9],"machine":[10],"is":[11],"used":[12,34],"for":[13],"cellular":[14],"multi-phenotypic":[15],"mitotic":[16],"analysis":[17],"(MMA)":[18],"in":[19],"high":[20],"content":[21],"screening":[22],"(HCS).":[23],"Haralick":[24],"texture":[25],"subset":[27,32],"and":[28],"Zernike":[29],"polynomial":[30],"moment":[31],"are":[33],"respe":[35]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}