{"id":"https://openalex.org/W1860088740","doi":"https://doi.org/10.3233/isb-2010-0426","title":"POODLE-I: Disordered Region Prediction by Integrating POODLE Series and Structural Information Predictors Based on a Workflow Approach","display_name":"POODLE-I: Disordered Region Prediction by Integrating POODLE Series and Structural Information Predictors Based on a Workflow Approach","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W1860088740","doi":"https://doi.org/10.3233/isb-2010-0426","mag":"1860088740","pmid":"https://pubmed.ncbi.nlm.nih.gov/22430291"},"language":"en","primary_location":{"id":"doi:10.3233/isb-2010-0426","is_oa":false,"landing_page_url":"https://doi.org/10.3233/isb-2010-0426","pdf_url":null,"source":{"id":"https://openalex.org/S120694666","display_name":"In Silico Biology","issn_l":"1386-6338","issn":["1386-6338","1434-3207"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039198984","display_name":"Shuichi Hirose","orcid":null},"institutions":[{"id":"https://openalex.org/I73613424","display_name":"National Institute of Advanced Industrial Science and Technology","ror":"https://ror.org/01703db54","country_code":"JP","type":"government","lineage":["https://openalex.org/I73613424"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Shuichi Hirose","raw_affiliation_strings":["Computational Biology Research Center (CBRC), National\r\t\t\t Institute of Advanced Industrial Science and Technology (AIST), Tokyo,\r\t\t\t Japan","Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Research Center (CBRC), National\r\t\t\t Institute of Advanced Industrial Science and Technology (AIST), Tokyo,\r\t\t\t Japan","institution_ids":["https://openalex.org/I73613424"]},{"raw_affiliation_string":"Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan","institution_ids":["https://openalex.org/I73613424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043657069","display_name":"Kana Shimizu","orcid":"https://orcid.org/0000-0001-6452-9091"},"institutions":[{"id":"https://openalex.org/I73613424","display_name":"National Institute of Advanced Industrial Science and Technology","ror":"https://ror.org/01703db54","country_code":"JP","type":"government","lineage":["https://openalex.org/I73613424"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kana Shimizu","raw_affiliation_strings":["Computational Biology Research Center (CBRC), National\r\t\t\t Institute of Advanced Industrial Science and Technology (AIST), Tokyo,\r\t\t\t Japan","Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Research Center (CBRC), National\r\t\t\t Institute of Advanced Industrial Science and Technology (AIST), Tokyo,\r\t\t\t Japan","institution_ids":["https://openalex.org/I73613424"]},{"raw_affiliation_string":"Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan","institution_ids":["https://openalex.org/I73613424"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112493012","display_name":"Tamotsu Noguchi","orcid":null},"institutions":[{"id":"https://openalex.org/I73613424","display_name":"National Institute of Advanced Industrial Science and Technology","ror":"https://ror.org/01703db54","country_code":"JP","type":"government","lineage":["https://openalex.org/I73613424"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tamotsu Noguchi","raw_affiliation_strings":["Computational Biology Research Center (CBRC), National\r\t\t\t Institute of Advanced Industrial Science and Technology (AIST), Tokyo,\r\t\t\t Japan","Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Research Center (CBRC), National\r\t\t\t Institute of Advanced Industrial Science and Technology (AIST), Tokyo,\r\t\t\t Japan","institution_ids":["https://openalex.org/I73613424"]},{"raw_affiliation_string":"Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan","institution_ids":["https://openalex.org/I73613424"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5039198984"],"corresponding_institution_ids":["https://openalex.org/I73613424"],"apc_list":null,"apc_paid":null,"fwci":1.2254,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.77135102,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"10","issue":"3-4","first_page":"185","last_page":"191"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9289000034332275,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.5593713521957397},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.522629976272583},{"id":"https://openalex.org/keywords/perspective","display_name":"Perspective (graphical)","score":0.5116710662841797},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4912852644920349},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.33766624331474304},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.33606353402137756},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.32151246070861816},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.21347180008888245},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.0716044008731842}],"concepts":[{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.5593713521957397},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.522629976272583},{"id":"https://openalex.org/C12713177","wikidata":"https://www.wikidata.org/wiki/Q1900281","display_name":"Perspective (graphical)","level":2,"score":0.5116710662841797},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4912852644920349},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33766624331474304},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.33606353402137756},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.32151246070861816},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.21347180008888245},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0716044008731842}],"mesh":[{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053181","descriptor_name":"Caspase 8","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D053181","descriptor_name":"Caspase 8","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D053181","descriptor_name":"Caspase 8","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3233/isb-2010-0426","is_oa":false,"landing_page_url":"https://doi.org/10.3233/isb-2010-0426","pdf_url":null,"source":{"id":"https://openalex.org/S120694666","display_name":"In Silico Biology","issn_l":"1386-6338","issn":["1386-6338","1434-3207"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation","raw_type":"journal-article"},{"id":"pmid:22430291","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22430291","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In silico biology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Industry, innovation and infrastructure","score":0.4699999988079071,"id":"https://metadata.un.org/sdg/9"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320337380","display_name":"Division of Mathematical Sciences","ror":"https://ror.org/051fftw81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2546704476","https://openalex.org/W2081035100","https://openalex.org/W2884654900","https://openalex.org/W2327228951","https://openalex.org/W2497175360","https://openalex.org/W1544898319","https://openalex.org/W3118799476","https://openalex.org/W1767718647","https://openalex.org/W2795043317"],"abstract_inverted_index":{"Under":[0],"physiological":[1],"conditions,":[2],"many":[3],"proteins":[4,180],"that":[5,81,119,133,150],"include":[6],"a":[7,32,64,96,142],"region":[8,99,112],"lacking":[9],"well-defined":[10],"three-dimensional":[11,52],"structures":[12,53],"have":[13,62],"been":[14],"identified,":[15],"especially":[16],"in":[17,69,154,166,179],"eukaryotes.":[18],"These":[19],"regions":[20,61,124,178],"often":[21],"play":[22],"an":[23,42,172],"important":[24],"biological":[25],"cellular":[26],"role,":[27],"although":[28],"they":[29,36,45],"cannot":[30],"form":[31],"stable":[33],"structure.":[34],"Therefore,":[35],"are":[37,82],"biologically":[38],"remarkable":[39],"phenomena.":[40],"From":[41],"industrial":[43],"perspective,":[44],"can":[46],"provide":[47,79],"useful":[48,83],"information":[49,134,138],"for":[50,84,93,175],"determining":[51],"or":[54],"designing":[55],"drugs.":[56],"For":[57],"these":[58],"reasons,":[59],"disordered":[60,98,111,123,177],"attracted":[63],"great":[65],"deal":[66],"of":[67,87,110,122,141],"attention":[68],"recent":[70],"years.":[71],"Their":[72],"accurate":[73],"prediction":[74,100,104],"is":[75,95,171,189],"therefore":[76],"anticipated":[77],"to":[78,127],"annotations":[80],"wide":[85],"range":[86],"applications.":[88],"POODLE-I":[89,102,131,156,170],"(where":[90],"\"I\"":[91],"stands":[92],"integration)":[94],"web-based":[97],"system.":[101],"integrates":[103],"results":[105],"obtained":[106],"from":[107,116,182],"three":[108],"kinds":[109],"predictors":[113],"(POODLEs)":[114],"developed":[115],"the":[117,120,159,163,183],"viewpoint":[118],"characteristics":[121],"change":[125],"according":[126],"their":[128],"length.":[129],"Furthermore,":[130],"combines":[132],"with":[135,147],"predicted":[136],"structural":[137],"by":[139],"application":[140,188],"workflow":[143],"approach.":[144],"When":[145],"compared":[146],"server":[148],"teams":[149],"showed":[151],"best":[152],"performance":[153,165],"CASP8,":[155],"ranked":[157],"among":[158],"top":[160],"and":[161],"exhibited":[162],"highest":[164],"predicting":[167],"unfolded":[168],"proteins.":[169],"efficient":[173],"tool":[174],"detecting":[176],"solely":[181],"amino":[184],"acid":[185],"sequence.":[186],"The":[187],"freely":[190],"available":[191],"at":[192],"http://mbs.cbrc.jp/poodle/poodle-i.html.":[193]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5}],"updated_date":"2026-06-23T06:36:01.041984","created_date":"2025-10-10T00:00:00"}