{"id":"https://openalex.org/W1627028742","doi":"https://doi.org/10.3233/isb-2009-0396","title":"An Emergent Self-Organizing Map Based Analysis Pipeline for Comparative Metabolome Studies","display_name":"An Emergent Self-Organizing Map Based Analysis Pipeline for Comparative Metabolome Studies","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W1627028742","doi":"https://doi.org/10.3233/isb-2009-0396","mag":"1627028742","pmid":"https://pubmed.ncbi.nlm.nih.gov/20109147"},"language":"en","primary_location":{"id":"doi:10.3233/isb-2009-0396","is_oa":false,"landing_page_url":"https://doi.org/10.3233/isb-2009-0396","pdf_url":null,"source":{"id":"https://openalex.org/S120694666","display_name":"In Silico Biology","issn_l":"1386-6338","issn":["1386-6338","1434-3207"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://orbilu.uni.lu/handle/10993/17740","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049656724","display_name":"Isam Haddad","orcid":null},"institutions":[{"id":"https://openalex.org/I94509681","display_name":"Technische Universit\u00e4t Braunschweig","ror":"https://ror.org/010nsgg66","country_code":"DE","type":"education","lineage":["https://openalex.org/I94509681"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Isam Haddad","raw_affiliation_strings":["Technische Universit\u00e4t Braunschweig, Institute of\r\t\t\t Microbiology, Braunschweig, Germany","Technische Universit\u00e4t Braunschweig, Institute of Microbiology, Braunschweig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute of\r\t\t\t Microbiology, Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute of Microbiology, Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077222776","display_name":"Karsten Hiller","orcid":"https://orcid.org/0000-0001-9322-5820"},"institutions":[{"id":"https://openalex.org/I186903577","display_name":"University of Luxembourg","ror":"https://ror.org/036x5ad56","country_code":"LU","type":"education","lineage":["https://openalex.org/I186903577"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["LU","US"],"is_corresponding":false,"raw_author_name":"Karsten Hiller","raw_affiliation_strings":["Massachusetts Institute of Technology, Department of\r\t\t\t Chemical Engineering, Cambridge, MA 02140, USA","University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > > ; Massachusetts Institute of Technology, Department of Chemical Engineering, Cambridge, MA 02140, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology, Department of\r\t\t\t Chemical Engineering, Cambridge, MA 02140, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > > ; Massachusetts Institute of Technology, Department of Chemical Engineering, Cambridge, MA 02140, USA","institution_ids":["https://openalex.org/I63966007","https://openalex.org/I186903577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082083860","display_name":"Eliane Frimmersdorf","orcid":null},"institutions":[{"id":"https://openalex.org/I94509681","display_name":"Technische Universit\u00e4t Braunschweig","ror":"https://ror.org/010nsgg66","country_code":"DE","type":"education","lineage":["https://openalex.org/I94509681"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Eliane Frimmersdorf","raw_affiliation_strings":["Technische Universit\u00e4t Braunschweig, Department of\r\t\t\t Bioinformatics and Biochemistry, Braunschweig, Germany","Technische Universit\u00e4t Braunschweig, Department of Bioinformatics and Biochemistry, Braunschweig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Department of\r\t\t\t Bioinformatics and Biochemistry, Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Department of Bioinformatics and Biochemistry, Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086827945","display_name":"Beatrice Benkert","orcid":null},"institutions":[{"id":"https://openalex.org/I94509681","display_name":"Technische Universit\u00e4t Braunschweig","ror":"https://ror.org/010nsgg66","country_code":"DE","type":"education","lineage":["https://openalex.org/I94509681"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Beatrice Benkert","raw_affiliation_strings":["Technische Universit\u00e4t Braunschweig, Institute of\r\t\t\t Microbiology, Braunschweig, Germany","Technische Universit\u00e4t Braunschweig, Institute of Microbiology, Braunschweig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute of\r\t\t\t Microbiology, Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute of Microbiology, Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043042218","display_name":"Dietmar Schomburg","orcid":"https://orcid.org/0000-0002-3354-822X"},"institutions":[{"id":"https://openalex.org/I94509681","display_name":"Technische Universit\u00e4t Braunschweig","ror":"https://ror.org/010nsgg66","country_code":"DE","type":"education","lineage":["https://openalex.org/I94509681"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dietmar Schomburg","raw_affiliation_strings":["Technische Universit\u00e4t Braunschweig, Department of\r\t\t\t Bioinformatics and Biochemistry, Braunschweig, Germany","Technische Universit\u00e4t Braunschweig, Department of Bioinformatics and Biochemistry, Braunschweig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Department of\r\t\t\t Bioinformatics and Biochemistry, Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Department of Bioinformatics and Biochemistry, Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041916369","display_name":"Dieter Jahn","orcid":"https://orcid.org/0000-0002-4064-9205"},"institutions":[{"id":"https://openalex.org/I94509681","display_name":"Technische Universit\u00e4t Braunschweig","ror":"https://ror.org/010nsgg66","country_code":"DE","type":"education","lineage":["https://openalex.org/I94509681"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dieter Jahn","raw_affiliation_strings":["Technische Universit\u00e4t Braunschweig, Institute of\r\t\t\t Microbiology, Braunschweig, Germany","Technische Universit\u00e4t Braunschweig, Institute of Microbiology, Braunschweig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute of\r\t\t\t Microbiology, Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute of Microbiology, Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6847,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.68317473,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"9","issue":"4","first_page":"163","last_page":"178"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolome","display_name":"Metabolome","score":0.7662386894226074},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.6920776963233948},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.46621188521385193},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.407992959022522},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.38297224044799805},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.222116619348526},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.20402002334594727},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.16847756505012512},{"id":"https://openalex.org/keywords/metabolomics","display_name":"Metabolomics","score":0.1458020806312561}],"concepts":[{"id":"https://openalex.org/C135870905","wikidata":"https://www.wikidata.org/wiki/Q903667","display_name":"Metabolome","level":3,"score":0.7662386894226074},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.6920776963233948},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.46621188521385193},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.407992959022522},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38297224044799805},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.222116619348526},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.20402002334594727},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.16847756505012512},{"id":"https://openalex.org/C21565614","wikidata":"https://www.wikidata.org/wiki/Q12149006","display_name":"Metabolomics","level":2,"score":0.1458020806312561},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008433","descriptor_name":"Mathematics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008433","descriptor_name":"Mathematics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008433","descriptor_name":"Mathematics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D048230","descriptor_name":"Corynebacterium glutamicum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D048230","descriptor_name":"Corynebacterium glutamicum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D048230","descriptor_name":"Corynebacterium glutamicum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053719","descriptor_name":"Tandem Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053719","descriptor_name":"Tandem Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053719","descriptor_name":"Tandem Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055442","descriptor_name":"Metabolome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055442","descriptor_name":"Metabolome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055442","descriptor_name":"Metabolome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057166","descriptor_name":"High-Throughput Screening Assays","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057166","descriptor_name":"High-Throughput Screening Assays","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057166","descriptor_name":"High-Throughput Screening Assays","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3233/isb-2009-0396","is_oa":false,"landing_page_url":"https://doi.org/10.3233/isb-2009-0396","pdf_url":null,"source":{"id":"https://openalex.org/S120694666","display_name":"In Silico Biology","issn_l":"1386-6338","issn":["1386-6338","1434-3207"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation","raw_type":"journal-article"},{"id":"pmid:20109147","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20109147","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"In silico biology","raw_type":null},{"id":"pmh:oai:orbilu.uni.lu:10993/17740","is_oa":true,"landing_page_url":"http://orbilu.uni.lu/handle/10993/17740","pdf_url":null,"source":{"id":"https://openalex.org/S4306401815","display_name":"Open Repository and Bibliography (University of Luxembourg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I186903577","host_organization_name":"University of Luxembourg","host_organization_lineage":["https://openalex.org/I186903577"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"In Silico Biology. IOS Press (2009).","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:orbilu.uni.lu:10993/17740","is_oa":true,"landing_page_url":"http://orbilu.uni.lu/handle/10993/17740","pdf_url":null,"source":{"id":"https://openalex.org/S4306401815","display_name":"Open Repository and Bibliography (University of Luxembourg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I186903577","host_organization_name":"University of Luxembourg","host_organization_lineage":["https://openalex.org/I186903577"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"In Silico Biology. IOS Press (2009).","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W65738273","https://openalex.org/W565446105","https://openalex.org/W1549912426","https://openalex.org/W1556581371","https://openalex.org/W1594833373","https://openalex.org/W1656697623","https://openalex.org/W1946371345","https://openalex.org/W1966902043","https://openalex.org/W1978616194","https://openalex.org/W1986662234","https://openalex.org/W1987971958","https://openalex.org/W1993274386","https://openalex.org/W2013309732","https://openalex.org/W2034873249","https://openalex.org/W2042325710","https://openalex.org/W2055709457","https://openalex.org/W2061445382","https://openalex.org/W2061567983","https://openalex.org/W2072378785","https://openalex.org/W2074906123","https://openalex.org/W2084826641","https://openalex.org/W2095716650","https://openalex.org/W2098087167","https://openalex.org/W2100474154","https://openalex.org/W2106104287","https://openalex.org/W2118222199","https://openalex.org/W2124911115","https://openalex.org/W2129815183","https://openalex.org/W2135026494","https://openalex.org/W2135187880","https://openalex.org/W2137540340","https://openalex.org/W2142913541","https://openalex.org/W2150926065","https://openalex.org/W2151225518","https://openalex.org/W2159482845","https://openalex.org/W2159628188","https://openalex.org/W2160453515","https://openalex.org/W2162314707","https://openalex.org/W2164190876","https://openalex.org/W2169001593","https://openalex.org/W2308024112","https://openalex.org/W2432517183","https://openalex.org/W2883418803","https://openalex.org/W2981264952","https://openalex.org/W4211085285"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W3026037716","https://openalex.org/W4387653671","https://openalex.org/W3016783226","https://openalex.org/W4288081249","https://openalex.org/W2809568226","https://openalex.org/W3010372330","https://openalex.org/W2999239475"],"abstract_inverted_index":{"Modern":[0],"high-throughput":[1,52],"techniques":[2],"allow":[3],"for":[4,37,51,111,138,169,181],"the":[5,21,25,38,79,86,128,159,170,173,182],"identification":[6],"and":[7,27,70,99,119,186],"quantification":[8],"of":[9,11,20,29,40,60,88,148,172],"hundreds":[10],"metabolites":[12],"ofa":[13],"biological":[14],"system":[15],"which":[16],"cover":[17],"central":[18],"parts":[19],"metabolome.":[22],"Due":[23],"to":[24,77,126],"amount":[26],"complexity":[28],"obtained":[30,137],"data":[31,47,55,83,112,175],"there":[32],"is":[33,56,75],"an":[34],"increasing":[35],"need":[36],"development":[39],"appropriate":[41],"computational":[42],"interpretation":[43],"methods.":[44],"A":[45],"novel":[46],"analysis":[48,63,73,154],"pipeline":[49,155],"designed":[50],"determined":[53],"metabolomic":[54,82,135],"presented.":[57],"The":[58,153,164],"combination":[59],"principal":[61],"component":[62],"(PCA)":[64],"with":[65],"emergent":[66],"self-organizing":[67],"maps":[68],"(ESOM)":[69],"hierarchical":[71],"cluster":[72],"(HCA)algorithms":[74],"used":[76,168],"unravel":[78],"structure":[80],"underlying":[81],"sets,":[84],"including":[85],"detection":[87],"outliers.":[89],"Observed":[90],"differences":[91],"between":[92],"various":[93,115,144],"analyzed":[94,116,132,187],"metabolomes":[95],"are":[96],"automatically":[97],"mapped":[98],"visualized":[100],"using":[101],"KEGG":[102],"metabolic":[103,109,151],"pathway":[104],"maps.":[105],"This":[106],"way":[107],"typical":[108,180],"biomarker":[110],"sets":[113],"from":[114],"growth":[117,188],"conditions":[118],"genetic":[120],"backgrounds":[121],"become":[122],"visible.":[123],"In":[124],"order":[125],"validate":[127],"described":[129],"methods":[130],"we":[131],"time":[133],"resolved":[134],"datasets":[136],"Corynebacterium":[139],"glutamicum":[140],"cells":[141],"grown":[142],"on":[143],"carbon":[145,184],"sources":[146,185],"consisting":[147],"126":[149],"different":[150],"patterns.":[152],"was":[156,166],"implemented":[157],"in":[158],"user-friendly":[160],"Java":[161],"software":[162,165],"eSOMet.":[163],"successfully":[167],"clustering":[171],"metabolome":[174],"mentioned":[176],"above.":[177],"Metabolic":[178],"biomarkers":[179],"utilized":[183],"phases":[189],"were":[190],"identified.":[191]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}