{"id":"https://openalex.org/W2909211499","doi":"https://doi.org/10.3233/fi-2019-1762","title":"DNA Ion Detector and Logic Circulation Amplification Model Based on Mercury and Silver Ions","display_name":"DNA Ion Detector and Logic Circulation Amplification Model Based on Mercury and Silver Ions","publication_year":2019,"publication_date":"2019-01-16","ids":{"openalex":"https://openalex.org/W2909211499","doi":"https://doi.org/10.3233/fi-2019-1762","mag":"2909211499"},"language":"en","primary_location":{"id":"doi:10.3233/fi-2019-1762","is_oa":false,"landing_page_url":"https://doi.org/10.3233/fi-2019-1762","pdf_url":null,"source":{"id":"https://openalex.org/S39012697","display_name":"Fundamenta Informaticae","issn_l":"0169-2968","issn":["0169-2968","1875-8681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fundamenta Informaticae","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111671156","display_name":"Bingjie Guo","orcid":"https://orcid.org/0000-0002-9478-025X"},"institutions":[{"id":"https://openalex.org/I88830068","display_name":"Shaanxi Normal University","ror":"https://ror.org/0170z8493","country_code":"CN","type":"education","lineage":["https://openalex.org/I88830068"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bingjie Guo","raw_affiliation_strings":["Department of Life Science, Shaanxi Normal University, Xi\u2019an 710119, China. 862248582@qq.com, wangluhui@snnu.edu.cn, wu_tao@snnu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Science, Shaanxi Normal University, Xi\u2019an 710119, China. 862248582@qq.com, wangluhui@snnu.edu.cn, wu_tao@snnu.edu.cn","institution_ids":["https://openalex.org/I88830068"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101879470","display_name":"Luhui Wang","orcid":"https://orcid.org/0000-0002-3582-7265"},"institutions":[{"id":"https://openalex.org/I88830068","display_name":"Shaanxi Normal University","ror":"https://ror.org/0170z8493","country_code":"CN","type":"education","lineage":["https://openalex.org/I88830068"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Luhui Wang","raw_affiliation_strings":["Department of Life Science, Shaanxi Normal University, Xi\u2019an 710119, China. 862248582@qq.com, wangluhui@snnu.edu.cn, wu_tao@snnu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Science, Shaanxi Normal University, Xi\u2019an 710119, China. 862248582@qq.com, wangluhui@snnu.edu.cn, wu_tao@snnu.edu.cn","institution_ids":["https://openalex.org/I88830068"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026178999","display_name":"Tao Wu","orcid":"https://orcid.org/0000-0002-0629-8421"},"institutions":[{"id":"https://openalex.org/I88830068","display_name":"Shaanxi Normal University","ror":"https://ror.org/0170z8493","country_code":"CN","type":"education","lineage":["https://openalex.org/I88830068"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tao Wu","raw_affiliation_strings":["Department of Life Science, Shaanxi Normal University, Xi\u2019an 710119, China. 862248582@qq.com, wangluhui@snnu.edu.cn, wu_tao@snnu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Science, Shaanxi Normal University, Xi\u2019an 710119, China. 862248582@qq.com, wangluhui@snnu.edu.cn, wu_tao@snnu.edu.cn","institution_ids":["https://openalex.org/I88830068"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008347393","display_name":"Yafei Dong","orcid":"https://orcid.org/0000-0002-1702-2260"},"institutions":[{"id":"https://openalex.org/I88830068","display_name":"Shaanxi Normal University","ror":"https://ror.org/0170z8493","country_code":"CN","type":"education","lineage":["https://openalex.org/I88830068"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yafei Dong","raw_affiliation_strings":["Department of Life Science & National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, Shaanxi Normal University, Xi\u2019an 710119, China. dongyf@snnu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Science & National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, Shaanxi Normal University, Xi\u2019an 710119, China. dongyf@snnu.edu.cn","institution_ids":["https://openalex.org/I88830068"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111671156"],"corresponding_institution_ids":["https://openalex.org/I88830068"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00282832,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"164","issue":"2-3","first_page":"195","last_page":"205"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/logic-gate","display_name":"Logic gate","score":0.7900902032852173},{"id":"https://openalex.org/keywords/detector","display_name":"Detector","score":0.6144357919692993},{"id":"https://openalex.org/keywords/and-gate","display_name":"AND gate","score":0.5592129230499268},{"id":"https://openalex.org/keywords/or-gate","display_name":"OR gate","score":0.5470600128173828},{"id":"https://openalex.org/keywords/and-or-invert","display_name":"AND-OR-Invert","score":0.4853019118309021},{"id":"https://openalex.org/keywords/cascade","display_name":"Cascade","score":0.48138144612312317},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4667155146598816},{"id":"https://openalex.org/keywords/logic-family","display_name":"Logic family","score":0.4434872269630432},{"id":"https://openalex.org/keywords/pass-transistor-logic","display_name":"Pass transistor logic","score":0.4198456406593323},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.41069096326828003},{"id":"https://openalex.org/keywords/electronic-engineering","display_name":"Electronic engineering","score":0.3243488669395447},{"id":"https://openalex.org/keywords/logic-synthesis","display_name":"Logic synthesis","score":0.3231545686721802},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.2620290517807007},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.2493012249469757},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.19918522238731384},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.17650213837623596},{"id":"https://openalex.org/keywords/voltage","display_name":"Voltage","score":0.16428184509277344},{"id":"https://openalex.org/keywords/transistor","display_name":"Transistor","score":0.12886646389961243},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.10218513011932373},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.061312854290008545}],"concepts":[{"id":"https://openalex.org/C131017901","wikidata":"https://www.wikidata.org/wiki/Q170451","display_name":"Logic gate","level":2,"score":0.7900902032852173},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.6144357919692993},{"id":"https://openalex.org/C10418432","wikidata":"https://www.wikidata.org/wiki/Q560370","display_name":"AND gate","level":3,"score":0.5592129230499268},{"id":"https://openalex.org/C58140894","wikidata":"https://www.wikidata.org/wiki/Q560398","display_name":"OR gate","level":4,"score":0.5470600128173828},{"id":"https://openalex.org/C130126468","wikidata":"https://www.wikidata.org/wiki/Q4652943","display_name":"AND-OR-Invert","level":5,"score":0.4853019118309021},{"id":"https://openalex.org/C34146451","wikidata":"https://www.wikidata.org/wiki/Q5048094","display_name":"Cascade","level":2,"score":0.48138144612312317},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4667155146598816},{"id":"https://openalex.org/C162454741","wikidata":"https://www.wikidata.org/wiki/Q173359","display_name":"Logic family","level":4,"score":0.4434872269630432},{"id":"https://openalex.org/C198521697","wikidata":"https://www.wikidata.org/wiki/Q7142438","display_name":"Pass transistor logic","level":4,"score":0.4198456406593323},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.41069096326828003},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.3243488669395447},{"id":"https://openalex.org/C157922185","wikidata":"https://www.wikidata.org/wiki/Q173198","display_name":"Logic synthesis","level":3,"score":0.3231545686721802},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2620290517807007},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2493012249469757},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.19918522238731384},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.17650213837623596},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.16428184509277344},{"id":"https://openalex.org/C172385210","wikidata":"https://www.wikidata.org/wiki/Q5339","display_name":"Transistor","level":3,"score":0.12886646389961243},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.10218513011932373},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.061312854290008545},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3233/fi-2019-1762","is_oa":false,"landing_page_url":"https://doi.org/10.3233/fi-2019-1762","pdf_url":null,"source":{"id":"https://openalex.org/S39012697","display_name":"Fundamenta Informaticae","issn_l":"0169-2968","issn":["0169-2968","1875-8681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fundamenta Informaticae","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1916790358","https://openalex.org/W1980026607","https://openalex.org/W1980451925","https://openalex.org/W1984139638","https://openalex.org/W1984687418","https://openalex.org/W1985548882","https://openalex.org/W1988808142","https://openalex.org/W2000914047","https://openalex.org/W2003523669","https://openalex.org/W2005461604","https://openalex.org/W2012384562","https://openalex.org/W2012575164","https://openalex.org/W2020243879","https://openalex.org/W2030198190","https://openalex.org/W2032118018","https://openalex.org/W2035792726","https://openalex.org/W2045751236","https://openalex.org/W2053080832","https://openalex.org/W2059331722","https://openalex.org/W2064267134","https://openalex.org/W2067557961","https://openalex.org/W2076322071","https://openalex.org/W2078342889","https://openalex.org/W2084513472","https://openalex.org/W2098263168","https://openalex.org/W2108243350","https://openalex.org/W2126160338","https://openalex.org/W2311199093","https://openalex.org/W2313270208","https://openalex.org/W2374290597","https://openalex.org/W2395250299","https://openalex.org/W2421456512","https://openalex.org/W2474945984","https://openalex.org/W2555649532","https://openalex.org/W2593869148","https://openalex.org/W2768734115"],"related_works":["https://openalex.org/W2789662562","https://openalex.org/W1576731273","https://openalex.org/W1504140885","https://openalex.org/W2029162371","https://openalex.org/W2997751809","https://openalex.org/W1017999001","https://openalex.org/W2140883167","https://openalex.org/W1979361505","https://openalex.org/W2290310756","https://openalex.org/W2073510429"],"abstract_inverted_index":{"Here,":[0],"two":[1,23,54,79,110],"two-way":[2],"ion":[3,28,81],"detector":[4],"(TWID)":[5],"and":[6,12,26,39,94,166,191],"one":[7],"DNA":[8,176],"cascade":[9],"logic":[10,88,104,111,114,121,129,136,152,177],"circuit":[11],"signal":[13,144],"amplifier":[14],"model":[15,115,188],"had":[16],"been":[17],"created.":[18],"Firstly,":[19],"we":[20,99,182],"have":[21],"constructed":[22,100],"bidirectional":[24,80],"mercury":[25,38],"silver":[27,40],"detectors,":[29],"both":[30],"of":[31,56,67,86,119,126,143,160,172,186],"which":[32,131],"can":[33,52],"be":[34],"used":[35],"to":[36,149],"detect":[37,53],"ions":[41,59],"at":[42,60],"the":[43,61,68,78,84,87,108,117,124,127,135,141,151,158,170,184],"same":[44,62],"time,":[45],"that":[46],"means":[47],"a":[48,101,163,173],"single":[49],"mol":[50],"ecule":[51],"kinds":[55],"heavy":[57],"metal":[58],"time.":[63],"The":[64],"unique":[65],"design":[66,85,171],"switches":[69],"offers":[70],"significant":[71],"advantages":[72],"over":[73],"existing":[74],"methods.":[75],"In":[76],"addition,":[77],"detectors":[82],"enable":[83],"gates":[89],"(OR,":[90],"AND)":[91],"using":[92],"Ag+":[93],"Hg2+":[95],"as":[96,123],"inputs.":[97],"Secondly,":[98],"two-level":[102],"\u201cAND\u201d":[103],"gate":[105,122],"by":[106,156,189],"combining":[107],"above":[109],"gates.":[112],"This":[113],"takes":[116],"output":[118,153],"\u201cOR\u201d":[120],"input":[125],"next":[128],"gate,":[130],"not":[132],"only":[133],"realizes":[134],"operation,":[137],"but":[138],"also":[139],"achieves":[140],"function":[142],"amplification.":[145],"We":[146],"are":[147],"able":[148],"recognize":[150],"signals":[154],"effortlessly":[155],"observing":[157],"amount":[159],"fluorescence.":[161],"It\u2019s":[162],"simple,":[164],"economic":[165],"safe":[167],"approach":[168],"for":[169],"complex":[174],"multiple-input":[175],"circulation":[178],"amplification":[179],"model.":[180],"Finally,":[181],"proved":[183],"feasibility":[185],"our":[187],"PAGE":[190],"fluorescence":[192],"alteration.":[193]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}