{"id":"https://openalex.org/W2399480997","doi":"https://doi.org/10.3233/978-1-61499-432-9-111","title":"Adverse Drug Event Notification on a Semantic Interoperability Framework","display_name":"Adverse Drug Event Notification on a Semantic Interoperability Framework","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2399480997","doi":"https://doi.org/10.3233/978-1-61499-432-9-111","mag":"2399480997","pmid":"https://pubmed.ncbi.nlm.nih.gov/25160156"},"language":"en","primary_location":{"id":"doi:10.3233/978-1-61499-432-9-111","is_oa":false,"landing_page_url":"https://doi.org/10.3233/978-1-61499-432-9-111","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073313278","display_name":"Tobias Krahn","orcid":"https://orcid.org/0009-0001-5619-8138"},"institutions":[{"id":"https://openalex.org/I202367325","display_name":"Oldenburger Institut f\u00fcr Informatik","ror":"https://ror.org/003sav189","country_code":"DE","type":"facility","lineage":["https://openalex.org/I202367325"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Krahn Tobias","raw_affiliation_strings":["OFFIS - Institute for Information Technology, Oldenburg, Germany"],"affiliations":[{"raw_affiliation_string":"OFFIS - Institute for Information Technology, Oldenburg, Germany","institution_ids":["https://openalex.org/I202367325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062961780","display_name":"Marco Eichelberg","orcid":"https://orcid.org/0000-0002-8590-3318"},"institutions":[{"id":"https://openalex.org/I202367325","display_name":"Oldenburger Institut f\u00fcr Informatik","ror":"https://ror.org/003sav189","country_code":"DE","type":"facility","lineage":["https://openalex.org/I202367325"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Eichelberg Marco","raw_affiliation_strings":["OFFIS - Institute for Information Technology, Oldenburg, Germany"],"affiliations":[{"raw_affiliation_string":"OFFIS - Institute for Information Technology, Oldenburg, Germany","institution_ids":["https://openalex.org/I202367325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112100736","display_name":"Frerk M\u00fcller","orcid":null},"institutions":[{"id":"https://openalex.org/I202367325","display_name":"Oldenburger Institut f\u00fcr Informatik","ror":"https://ror.org/003sav189","country_code":"DE","type":"facility","lineage":["https://openalex.org/I202367325"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Müller Frerk","raw_affiliation_strings":["OFFIS - Institute for Information Technology, Oldenburg, Germany"],"affiliations":[{"raw_affiliation_string":"OFFIS - Institute for Information Technology, Oldenburg, Germany","institution_ids":["https://openalex.org/I202367325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059170956","display_name":"Suat G\u00f6n\u00fcl","orcid":"https://orcid.org/0000-0002-7352-8848"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gönül Suat","raw_affiliation_strings":["SRDC - Software Research and Development Center"],"affiliations":[{"raw_affiliation_string":"SRDC - Software Research and Development Center","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047907795","display_name":"G\u00f6k\u00e7e Banu Laleci Ert\u00fcrkmen","orcid":"https://orcid.org/0000-0002-6201-3849"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laleci Erturkmen Gokce B.","raw_affiliation_strings":["SRDC - Software Research and Development Center"],"affiliations":[{"raw_affiliation_string":"SRDC - Software Research and Development Center","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032773700","display_name":"Ali An\u0131l S\u0131nac\u0131","orcid":"https://orcid.org/0000-0003-4397-3382"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sinaci A. Anil","raw_affiliation_strings":["SRDC - Software Research and Development Center"],"affiliations":[{"raw_affiliation_string":"SRDC - Software Research and Development Center","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113846499","display_name":"H.-J\u00fcrgen Appelrath","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Appelrath H.-Jürgen","raw_affiliation_strings":["University of Oldenburg, Department of Computer Science"],"affiliations":[{"raw_affiliation_string":"University of Oldenburg, Department of Computer Science","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5073313278"],"corresponding_institution_ids":["https://openalex.org/I202367325"],"apc_list":null,"apc_paid":null,"fwci":0.6925,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.73249245,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"205","issue":null,"first_page":"111","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10215","display_name":"Semantic Web and Ontologies","score":0.9205999970436096,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10215","display_name":"Semantic Web and Ontologies","score":0.9205999970436096,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10703","display_name":"Business Process Modeling and Analysis","score":0.9146999716758728,"subfield":{"id":"https://openalex.org/subfields/1404","display_name":"Management Information Systems"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9067999720573425,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interoperability","display_name":"Interoperability","score":0.8152589201927185},{"id":"https://openalex.org/keywords/semantic-interoperability","display_name":"Semantic interoperability","score":0.6170241832733154},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6015720367431641},{"id":"https://openalex.org/keywords/event","display_name":"Event (particle physics)","score":0.5088493824005127},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.3025796413421631}],"concepts":[{"id":"https://openalex.org/C20136886","wikidata":"https://www.wikidata.org/wiki/Q749647","display_name":"Interoperability","level":2,"score":0.8152589201927185},{"id":"https://openalex.org/C192800085","wikidata":"https://www.wikidata.org/wiki/Q5258530","display_name":"Semantic interoperability","level":3,"score":0.6170241832733154},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6015720367431641},{"id":"https://openalex.org/C2779662365","wikidata":"https://www.wikidata.org/wiki/Q5416694","display_name":"Event (particle physics)","level":2,"score":0.5088493824005127},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.3025796413421631},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005060","descriptor_name":"Europe","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005060","descriptor_name":"Europe","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005060","descriptor_name":"Europe","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008498","descriptor_name":"Medical Record Linkage","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008498","descriptor_name":"Medical Record Linkage","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008498","descriptor_name":"Medical Record Linkage","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009323","descriptor_name":"Natural Language Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009323","descriptor_name":"Natural Language Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009323","descriptor_name":"Natural Language Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012660","descriptor_name":"Semantics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012660","descriptor_name":"Semantics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012660","descriptor_name":"Semantics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012985","descriptor_name":"Software Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012985","descriptor_name":"Software Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012985","descriptor_name":"Software Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016247","descriptor_name":"Information Storage and Retrieval","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":false},{"descriptor_ui":"D016907","descriptor_name":"Adverse Drug Reaction Reporting Systems","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":false},{"descriptor_ui":"D018875","descriptor_name":"Vocabulary, Controlled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018875","descriptor_name":"Vocabulary, Controlled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018875","descriptor_name":"Vocabulary, Controlled","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":false},{"descriptor_ui":"D057286","descriptor_name":"Electronic Health Records","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3233/978-1-61499-432-9-111","is_oa":false,"landing_page_url":"https://doi.org/10.3233/978-1-61499-432-9-111","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},{"id":"pmid:25160156","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25160156","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in health technology and informatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Industry, innovation and infrastructure","score":0.5400000214576721,"id":"https://metadata.un.org/sdg/9"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W4386953431","https://openalex.org/W2355850745","https://openalex.org/W2109385585","https://openalex.org/W2157800466","https://openalex.org/W2388051831","https://openalex.org/W4292980915","https://openalex.org/W2531681040","https://openalex.org/W2908350895","https://openalex.org/W1983403677"],"abstract_inverted_index":{"Adverse":[0],"drug":[1,18],"events":[2],"(ADEs)":[3],"are":[4,22,57],"common,":[5],"costly":[6],"and":[7,92,146,168],"one":[8],"of":[9,40,63,74,97,111,181],"the":[10,72,75,112,131,143,155,179],"most":[11],"important":[12],"issues":[13],"in":[14,50,127,134,152,160,178],"contemporary":[15],"pharmacotherapy.":[16],"Current":[17],"safety":[19],"surveillance":[20],"methods":[21],"largely":[23],"based":[24],"on":[25,46,61,108],"spontaneous":[26],"reports.":[27],"However,":[28],"this":[29],"is":[30,37],"known":[31],"to":[32,81,123,129,164],"be":[33,158],"rather":[34],"ineffective.":[35],"There":[36],"a":[38,88,135,175],"lack":[39],"automated":[41],"systems":[42,56,67,101],"checking":[43],"potential":[44],"ADEs":[45],"routine":[47],"data":[48,96,133,137],"captured":[49],"electronic":[51],"health":[52],"records":[53],"(EHRs);":[54],"present":[55],"usually":[58],"built":[59],"directly":[60],"top":[62],"specific":[64],"clinical":[65,94,99,162],"information":[66,100],"through":[68],"proprietary":[69],"interfaces.":[70],"In":[71],"context":[73],"European":[76],"project":[77],"\"SALUS\",":[78],"we":[79],"aim":[80],"provide":[82,130],"an":[83,121],"infrastructure":[84],"as":[85,87],"well":[86],"tool-set":[89],"for":[90,139],"accessing":[91],"analyzing":[93],"patient":[95,132],"heterogeneous":[98],"utilizing":[102],"standard":[103],"methods.":[104],"This":[105],"paper":[106],"focuses":[107],"two":[109],"components":[110],"SALUS":[113],"architecture:":[114],"The":[115,150],"\"Semantic":[116],"Interoperability":[117],"Layer\"":[118],"(SIL)":[119],"enables":[120],"access":[122],"disparate":[124],"EHR":[125],"sources":[126],"order":[128],"common":[136],"model":[138],"ADE":[140,166],"detection":[141,167],"within":[142],"\"ADE":[144],"Detection":[145],"Notification":[147],"Tool\"":[148],"(ANT).":[149],"SIL":[151],"combination":[153],"with":[154],"ANT":[156],"can":[157],"used":[159],"different":[161],"environments":[163],"increase":[165],"reporting":[169],"rates.":[170],"Thus,":[171],"our":[172],"approach":[173],"promises":[174],"profound":[176],"impact":[177],"domain":[180],"pharmacovigilance.":[182]},"counts_by_year":[{"year":2023,"cited_by_count":6},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}