{"id":"https://openalex.org/W4407833452","doi":"https://doi.org/10.3233/978-1-60750-588-4-1090","title":"The ObTiMA System – Ontology-based Managing of Clinical Trials","display_name":"The ObTiMA System – Ontology-based Managing of Clinical Trials","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W4407833452","doi":"https://doi.org/10.3233/978-1-60750-588-4-1090"},"language":"en","primary_location":{"id":"doi:10.3233/978-1-60750-588-4-1090","is_oa":true,"landing_page_url":"https://doi.org/10.3233/978-1-60750-588-4-1090","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.3233/978-1-60750-588-4-1090","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054197674","display_name":"Holger Stenzhorn","orcid":"https://orcid.org/0000-0001-9744-174X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stenzhorn Holger","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116374015","display_name":"Weiler Gabriele","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Weiler Gabriele","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047229883","display_name":"Mathias Brochhausen","orcid":"https://orcid.org/0000-0003-1834-3856"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brochhausen Mathias","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Schera Fatima","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Schera Fatima","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116374016","display_name":"Kritsotakis Vangelis","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kritsotakis Vangelis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087123353","display_name":"Manolis Tsiknakis","orcid":"https://orcid.org/0000-0001-8454-1450"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tsiknakis Manolis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116374017","display_name":"Kiefer Stephan","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kiefer Stephan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5029830172","display_name":"Norbert Graf","orcid":"https://orcid.org/0000-0002-2248-323X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Graf Norbert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4523,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.87006839,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10215","display_name":"Semantic Web and Ontologies","score":0.9573000073432922,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9509000182151794,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.7246156930923462},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5225524306297302},{"id":"https://openalex.org/keywords/epistemology","display_name":"Epistemology","score":0.08877992630004883},{"id":"https://openalex.org/keywords/philosophy","display_name":"Philosophy","score":0.08540278673171997}],"concepts":[{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.7246156930923462},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5225524306297302},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.08877992630004883},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.08540278673171997}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3233/978-1-60750-588-4-1090","is_oa":true,"landing_page_url":"https://doi.org/10.3233/978-1-60750-588-4-1090","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},{"id":"pmh:oai:fraunhofer.de:N-149088","is_oa":false,"landing_page_url":"http://publica.fraunhofer.de/documents/N-149088.html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400801","display_name":"Publikationsdatenbank der Fraunhofer-Gesellschaft (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Fraunhofer IBMT","raw_type":"Conference Paper"},{"id":"pmh:oai:publica.fraunhofer.de:publica/367816","is_oa":false,"landing_page_url":"https://publica.fraunhofer.de/handle/publica/367816","pdf_url":null,"source":{"id":"https://openalex.org/S4306400318","display_name":"Fraunhofer-Publica (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"conference paper"}],"best_oa_location":{"id":"doi:10.3233/978-1-60750-588-4-1090","is_oa":true,"landing_page_url":"https://doi.org/10.3233/978-1-60750-588-4-1090","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Clinical":[0],"Trial":[1],"Management":[2],"Systems":[3],"promise":[4],"to":[5,58],"help":[6],"researchers":[7],"in":[8,16,81,117],"managing":[9],"the":[10,51,82,85,121],"large":[11],"amounts":[12],"of":[13,84,91],"data":[14,29,53,77,103,109],"occurring":[15],"clinical":[17,96],"trials.":[18,63,105],"In":[19],"such":[20,47],"systems":[21],"Case":[22],"Report":[23],"Forms":[24],"for":[25,35,94,100],"capturing":[26],"all":[27],"patient":[28,102],"can":[30],"usually":[31],"be":[32,55],"defined":[33,116],"freely":[34],"a":[36,92],"given":[37],"trial.":[38],"But":[39],"if":[40],"database":[41],"definitions":[42,49],"are":[43],"automatically":[44],"derived":[45],"from":[46],"trial-specific":[48],"then":[50],"collected":[52],"cannot":[54],"easily":[56],"compared":[57],"or":[59],"integrated":[60],"into":[61],"other":[62],"We":[64],"address":[65],"this":[66],"interoperability":[67],"issue":[68],"with":[69],"an":[70,118],"approach":[71],"based":[72],"on":[73,113],"ontology":[74,119],"and":[75,98,125],"semantic":[76],"mediation.":[78],"This":[79],"resulted":[80],"development":[83],"ObTiMA":[86],"system":[87],"which":[88],"is":[89],"composed":[90],"component":[93],"setting-up":[95],"trials":[97],"another":[99],"handling":[101],"during":[104],"Both":[106],"components":[107],"offer":[108],"reusability":[110],"by":[111],"relying":[112],"shared":[114],"concepts":[115],"covering":[120],"whole":[122],"cancer":[123],"care":[124],"research":[126],"spectrum.":[127]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-02-22T00:00:00"}