{"id":"https://openalex.org/W78700891","doi":"https://doi.org/10.3233/978-1-60750-044-5-794","title":"Fractal Behaviour of Heart Rate Variability Reflects Severity in Stroke Patients","display_name":"Fractal Behaviour of Heart Rate Variability Reflects Severity in Stroke Patients","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W78700891","doi":"https://doi.org/10.3233/978-1-60750-044-5-794","mag":"78700891","pmid":"https://pubmed.ncbi.nlm.nih.gov/19745422"},"language":"en","primary_location":{"id":"doi:10.3233/978-1-60750-044-5-794","is_oa":true,"landing_page_url":"https://doi.org/10.3233/978-1-60750-044-5-794","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.3233/978-1-60750-044-5-794","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"D'Addio Gianni","orcid":null},"institutions":[{"id":"https://openalex.org/I4210105320","display_name":"Fondazione Salvatore Maugeri","ror":"https://ror.org/01e8tvg28","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210105320","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"D'Addio Gianni","raw_affiliation_strings":["S. Maugeri Foundation, Telese - Pavia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"S. Maugeri Foundation, Telese - Pavia, Italy","institution_ids":["https://openalex.org/I4210105320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069896436","display_name":"Graziamaria Corbi","orcid":"https://orcid.org/0000-0002-3441-889X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Corbi Graziamaria","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001761612","display_name":"Accardo Agostino","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Accardo Agostino","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Russo Giovanna","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Russo Giovanna","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072479964","display_name":"Nicola Ferrara","orcid":"https://orcid.org/0000-0001-8200-4942"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ferrara Nicola","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Mazzoleni M. Cristina","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mazzoleni M. Cristina","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5060208618","display_name":"Tanja Princi","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Princi Tanja","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.0614,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.93680463,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"150","issue":null,"first_page":"794","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11667","display_name":"Advanced Chemical Sensor Technologies","score":0.9825999736785889,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9803000092506409,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"Heart rate variability","score":0.7805896997451782},{"id":"https://openalex.org/keywords/fractal","display_name":"Fractal","score":0.6880043148994446},{"id":"https://openalex.org/keywords/fractal-dimension","display_name":"Fractal dimension","score":0.6718032956123352},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5196629762649536},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.5184645056724548},{"id":"https://openalex.org/keywords/stroke","display_name":"Stroke (engine)","score":0.5158716440200806},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.46042370796203613},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.43556949496269226},{"id":"https://openalex.org/keywords/lesion","display_name":"Lesion","score":0.42538702487945557},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3792005777359009},{"id":"https://openalex.org/keywords/surgery","display_name":"Surgery","score":0.14893698692321777},{"id":"https://openalex.org/keywords/mathematical-analysis","display_name":"Mathematical analysis","score":0.11976948380470276},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.0970468819141388}],"concepts":[{"id":"https://openalex.org/C71635504","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"Heart rate variability","level":4,"score":0.7805896997451782},{"id":"https://openalex.org/C40636538","wikidata":"https://www.wikidata.org/wiki/Q81392","display_name":"Fractal","level":2,"score":0.6880043148994446},{"id":"https://openalex.org/C26546657","wikidata":"https://www.wikidata.org/wiki/Q1412452","display_name":"Fractal dimension","level":3,"score":0.6718032956123352},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5196629762649536},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5184645056724548},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.5158716440200806},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.46042370796203613},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.43556949496269226},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.42538702487945557},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3792005777359009},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.14893698692321777},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.11976948380470276},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0970468819141388},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015599","descriptor_name":"Trauma Severity Indices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015599","descriptor_name":"Trauma Severity Indices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015599","descriptor_name":"Trauma Severity Indices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017709","descriptor_name":"Fractals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017709","descriptor_name":"Fractals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017709","descriptor_name":"Fractals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3233/978-1-60750-044-5-794","is_oa":true,"landing_page_url":"https://doi.org/10.3233/978-1-60750-044-5-794","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},{"id":"pmid:19745422","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19745422","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in health technology and informatics","raw_type":null},{"id":"pmh:oai:arts.units.it:11368/2286443","is_oa":true,"landing_page_url":"http://hdl.handle.net/11368/2286443","pdf_url":"http://ebooks.iospress.nl/publication/12775","source":{"id":"https://openalex.org/S4306400480","display_name":"ArTS Archivio della ricerca di Trieste (University of Trieste https://www.units.it/)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I142444530","host_organization_name":"University of Trieste","host_organization_lineage":["https://openalex.org/I142444530"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":{"id":"doi:10.3233/978-1-60750-044-5-794","is_oa":true,"landing_page_url":"https://doi.org/10.3233/978-1-60750-044-5-794","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6600000262260437,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1587895598","https://openalex.org/W1963902765","https://openalex.org/W1971318718","https://openalex.org/W1988157458","https://openalex.org/W1994233698","https://openalex.org/W2001129310","https://openalex.org/W2036171391","https://openalex.org/W2063255044","https://openalex.org/W2081313132","https://openalex.org/W2098592970","https://openalex.org/W2119120808","https://openalex.org/W2127732410","https://openalex.org/W2133589238","https://openalex.org/W2147437705","https://openalex.org/W2155362783","https://openalex.org/W2167723706","https://openalex.org/W2225785221","https://openalex.org/W2566350558","https://openalex.org/W2795191337"],"related_works":["https://openalex.org/W2394117909","https://openalex.org/W2896054214","https://openalex.org/W2355197944","https://openalex.org/W2017118246","https://openalex.org/W2354661593","https://openalex.org/W2382240109","https://openalex.org/W2368475191","https://openalex.org/W2391311021","https://openalex.org/W2389188284","https://openalex.org/W2026209355"],"abstract_inverted_index":{"Non-linear":[0],"parameters":[1,28],"obtained":[2],"from":[3,57,117,148,175],"heart":[4,21],"rate":[5,22],"variability":[6],"(HRV)":[7],"analysis":[8,160],"has":[9],"recently":[10],"been":[11],"recognized":[12],"to":[13,30,69,96,123,143,165,171,182],"provide":[14],"valuable":[15],"information":[16,163],"for":[17],"physiological":[18],"interpretation":[19],"of":[20,34],"fluctuation.":[23],"Among":[24],"the":[25,31,35,45,48,53,58,71,125,132,138,145,149,153],"numerous":[26],"non-linear":[27],"related":[29,164],"fractal":[32,65,77,112,126,159],"behaviour":[33],"HRV":[36,150,167],"signal,":[37],"two":[38,93],"classes":[39],"have":[40],"gained":[41],"wide":[42],"interest":[43],"in":[44,92,121,129,152],"last":[46],"years:":[47],"beta":[49],"exponent":[50],"based":[51,63],"on":[52,64],"1/f-like":[54,114],"relationship,":[55],"starting":[56],"spectral":[59],"power,":[60],"and":[61,76,83,113,186],"that":[62,141,158,169],"dimension.":[66],"In":[67],"order":[68],"evaluate":[70,124],"relationship":[72],"between":[73,184],"lesion's":[74,191],"severity":[75],"behaviour,":[78],"20":[79],"first-ever":[80],"stroke":[81,176,187],"subjects":[82,86,105,174,188],"10":[84],"healthy":[85],"were":[87,90],"studied.":[88],"Patients":[89],"divided":[91],"groups":[94],"according":[95],"single":[97],"or":[98],"multiple":[99],"medium":[100],"cerebral":[101],"artery":[102],"lesions.":[103],"All":[104],"underwent":[106],"24-hour":[107],"Holter":[108],"recording":[109],"analysed":[110],"by":[111,136],"techniques.":[115],"Differently":[116],"methods":[118],"usually":[119],"used":[120],"literature":[122],"dimension":[127],"(FD),":[128],"this":[130],"work":[131],"FD":[133,178],"was":[134],"extracted":[135],"using":[137],"Higuchi's":[139],"algorithm":[140],"permits":[142,170],"calculate":[144],"parameter":[146],"directly":[147],"sequences":[151],"time":[154],"domain.":[155],"Results":[156],"show":[157],"contains":[161],"relevant":[162],"different":[166,190],"dynamics":[168],"separate":[172],"normal":[173,185],"patients.":[177],"is":[179],"also":[180],"able":[181],"distinguish":[183],"with":[189],"severity.":[192]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-08-04T08:18:43.703281","created_date":"2025-10-10T00:00:00"}