{"id":"https://openalex.org/W92319542","doi":"https://doi.org/10.3233/978-1-60750-044-5-767","title":"GeneMining: Identification, Visualization, and Interpretation of Brain Ageing Signatures","display_name":"GeneMining: Identification, Visualization, and Interpretation of Brain Ageing Signatures","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W92319542","doi":"https://doi.org/10.3233/978-1-60750-044-5-767","mag":"92319542","pmid":"https://pubmed.ncbi.nlm.nih.gov/19745414"},"language":"en","primary_location":{"id":"doi:10.3233/978-1-60750-044-5-767","is_oa":false,"landing_page_url":"https://doi.org/10.3233/978-1-60750-044-5-767","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111973950","display_name":"Paola Salle","orcid":null},"institutions":[{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4210101743","display_name":"Laboratoire d'Informatique, de Robotique et de Micro\u00e9lectronique de Montpellier","ror":"https://ror.org/013yean28","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I151295451","https://openalex.org/I19894307","https://openalex.org/I4210101743","https://openalex.org/I4210159245","https://openalex.org/I4405261681"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Salle Paola","raw_affiliation_strings":["Montpellier Laboratory of Informatics, Robotics, and Microelectronics, Montpellier 2 University, National Center for Scientific Research, 34392 Montpellier, France. paola.salle@lirmm.fr"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Montpellier Laboratory of Informatics, Robotics, and Microelectronics, Montpellier 2 University, National Center for Scientific Research, 34392 Montpellier, France. paola.salle@lirmm.fr","institution_ids":["https://openalex.org/I19894307","https://openalex.org/I4210101743"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Bringay Sandra","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bringay Sandra","raw_affiliation_strings":["Fouille de donn\u00e9es environnementales"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fouille de donn\u00e9es environnementales","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075318719","display_name":"Maguelonne Teisseire","orcid":"https://orcid.org/0000-0001-9313-6414"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Teisseire Maguelonne","raw_affiliation_strings":["Fouille de donn\u00e9es environnementales"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fouille de donn\u00e9es environnementales","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011411710","display_name":"Feirouz Chakkour","orcid":null},"institutions":[{"id":"https://openalex.org/I4210101743","display_name":"Laboratoire d'Informatique, de Robotique et de Micro\u00e9lectronique de Montpellier","ror":"https://ror.org/013yean28","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I151295451","https://openalex.org/I19894307","https://openalex.org/I4210101743","https://openalex.org/I4210159245","https://openalex.org/I4405261681"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Chakkour Feirouz","raw_affiliation_strings":["Laboratoire d'Informatique de Robotique et de Micro\u00e9lectronique de Montpellier"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'Informatique de Robotique et de Micro\u00e9lectronique de Montpellier","institution_ids":["https://openalex.org/I4210101743"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Roche Mathieu","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Roche Mathieu","raw_affiliation_strings":["Exploration et exploitation de donn\u00e9es textuelles"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Exploration et exploitation de donn\u00e9es textuelles","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rassoul Ronza Abdel","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rassoul Ronza Abdel","raw_affiliation_strings":["Microbiologie et Pathologie Cellulaire Infectieuse"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiologie et Pathologie Cellulaire Infectieuse","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075186690","display_name":"Jean\u2010Michel Verdier","orcid":"https://orcid.org/0000-0002-7252-1556"},"institutions":[{"id":"https://openalex.org/I4387152481","display_name":"M\u00e9canismes mol\u00e9culaires dans les d\u00e9mences neurod\u00e9g\u00e9n\u00e9ratives","ror":"https://ror.org/008qs6838","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I159885104","https://openalex.org/I19894307","https://openalex.org/I2746051580","https://openalex.org/I4387152481"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Verdier Jean-Michel","raw_affiliation_strings":["M\u00e9canismes mol\u00e9culaires dans les d\u00e9mences neurod\u00e9g\u00e9n\u00e9ratives"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M\u00e9canismes mol\u00e9culaires dans les d\u00e9mences neurod\u00e9g\u00e9n\u00e9ratives","institution_ids":["https://openalex.org/I4387152481"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011865615","display_name":"Gina Devau","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Devau Gina","raw_affiliation_strings":["Microbiologie et Pathologie Cellulaire Infectieuse"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiologie et Pathologie Cellulaire Infectieuse","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.8211,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.83917361,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"150","issue":null,"first_page":"767","last_page":"71"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10538","display_name":"Data Mining Algorithms and Applications","score":0.9940000176429749,"subfield":{"id":"https://openalex.org/subfields/1710","display_name":"Information Systems"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6928849220275879},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.6625028848648071},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.631729006767273},{"id":"https://openalex.org/keywords/exploit","display_name":"Exploit","score":0.6216503381729126},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5375030040740967},{"id":"https://openalex.org/keywords/multidisciplinary-approach","display_name":"Multidisciplinary approach","score":0.5369341969490051},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.4979991912841797},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.24945205450057983},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11037465929985046}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6928849220275879},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6625028848648071},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.631729006767273},{"id":"https://openalex.org/C165696696","wikidata":"https://www.wikidata.org/wiki/Q11287","display_name":"Exploit","level":2,"score":0.6216503381729126},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5375030040740967},{"id":"https://openalex.org/C22467394","wikidata":"https://www.wikidata.org/wiki/Q849359","display_name":"Multidisciplinary approach","level":2,"score":0.5369341969490051},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4979991912841797},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.24945205450057983},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11037465929985046},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3233/978-1-60750-044-5-767","is_oa":false,"landing_page_url":"https://doi.org/10.3233/978-1-60750-044-5-767","pdf_url":null,"source":{"id":"https://openalex.org/S4210179765","display_name":"Studies in health technology and informatics","issn_l":"0926-9630","issn":["0926-9630","1879-8365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Health Technology and Informatics","raw_type":"book-chapter"},{"id":"pmid:19745414","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19745414","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in health technology and informatics","raw_type":null},{"id":"pmh:oai:HAL:lirmm-00395142v1","is_oa":false,"landing_page_url":"https://hal-lirmm.ccsd.cnrs.fr/lirmm-00395142","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.mie2009.org/","raw_type":"info:eu-repo/semantics/bookPart"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4699999988079071,"display_name":"Industry, innovation and infrastructure","id":"https://metadata.un.org/sdg/9"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W37503237","https://openalex.org/W1518700327","https://openalex.org/W1642278221","https://openalex.org/W1877868027","https://openalex.org/W1985659039","https://openalex.org/W1985802523","https://openalex.org/W1999486930","https://openalex.org/W2015370254","https://openalex.org/W2107139603","https://openalex.org/W2118843309","https://openalex.org/W2126703991","https://openalex.org/W2144544802","https://openalex.org/W2150926065","https://openalex.org/W2157795344","https://openalex.org/W2267898329","https://openalex.org/W2487292128","https://openalex.org/W4298339663"],"related_works":["https://openalex.org/W17155033","https://openalex.org/W3207760230","https://openalex.org/W1496222301","https://openalex.org/W4312814274","https://openalex.org/W1590307681","https://openalex.org/W2536018345","https://openalex.org/W4285370786","https://openalex.org/W2296488620","https://openalex.org/W2358353312","https://openalex.org/W2353836703"],"abstract_inverted_index":{"Transcriptomic":[0],"technologies":[1,22],"are":[2,30],"promising":[3],"tools":[4,58,87],"for":[5],"identifying":[6],"new":[7,48,92],"genes":[8],"involved":[9],"in":[10,14],"cerebral":[11],"ageing":[12,68,79],"or":[13],"neurodegenerative":[15],"diseases":[16],"such":[17,52],"as":[18],"Alzheimer's":[19],"disease.":[20],"These":[21],"produce":[23],"massive":[24],"biological":[25],"data,":[26,53],"which":[27,44],"so":[28],"far":[29],"extremely":[31],"difficult":[32],"to":[33,50,55,59,62,72,90],"exploit.":[34],"In":[35,70],"this":[36],"context,":[37],"we":[38,82],"propose":[39],"GeneMining,":[40],"a":[41,91],"multidisciplinary":[42],"methodology,":[43],"aims":[45],"at":[46],"developing":[47],"strategies":[49],"analyse":[51],"and":[54,65,84],"design":[56],"interactive":[57],"help":[60],"biologists":[61],"identify,":[63],"visualize":[64],"interpret":[66],"brain":[67,78],"signatures.":[69],"order":[71],"address":[73],"the":[74],"specific":[75],"problem":[76],"of":[77],"signatures":[80],"discovery,":[81],"combine":[83],"apply":[85],"existing":[86],"with":[88],"emphasis":[89],"efficient":[93],"data":[94],"mining":[95],"method":[96],"based":[97],"on":[98],"sequential":[99],"patterns.":[100]},"counts_by_year":[],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}