{"id":"https://openalex.org/W4385894277","doi":"https://doi.org/10.25080/gerudo-f2bc6f59-00d","title":"itk-elastix: Medical image registration in Python","display_name":"itk-elastix: Medical image registration in Python","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4385894277","doi":"https://doi.org/10.25080/gerudo-f2bc6f59-00d"},"language":"en","primary_location":{"id":"doi:10.25080/gerudo-f2bc6f59-00d","is_oa":true,"landing_page_url":"https://doi.org/10.25080/gerudo-f2bc6f59-00d","pdf_url":"https://conference.scipy.org/proceedings/scipy2023/pdfs/konstantinos_ntatsis.pdf","source":{"id":"https://openalex.org/S4220651651","display_name":"Proceedings of the Python in Science Conferences","issn_l":"2575-9752","issn":["2575-9752"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Python in Science Conference","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://conference.scipy.org/proceedings/scipy2023/pdfs/konstantinos_ntatsis.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025493773","display_name":"Konstantinos Ntatsis","orcid":null},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Konstantinos Ntatsis","raw_affiliation_strings":["Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059039994","display_name":"Niels Dekker","orcid":null},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Niels Dekker","raw_affiliation_strings":["Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053133916","display_name":"Viktor van der Valk","orcid":"https://orcid.org/0000-0002-8077-9274"},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Viktor van der Valk","raw_affiliation_strings":["Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065233547","display_name":"Tom Birdsong","orcid":null},"institutions":[{"id":"https://openalex.org/I74786994","display_name":"Kitware (United States)","ror":"https://ror.org/02s2acn37","country_code":"US","type":"company","lineage":["https://openalex.org/I74786994"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tom Birdsong","raw_affiliation_strings":["Medical Computing Group, Kitware, Inc, Carrboro, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Computing Group, Kitware, Inc, Carrboro, NC, USA","institution_ids":["https://openalex.org/I74786994"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011631962","display_name":"D\u017eenan Zuki\u0107","orcid":"https://orcid.org/0000-0002-9546-9703"},"institutions":[{"id":"https://openalex.org/I74786994","display_name":"Kitware (United States)","ror":"https://ror.org/02s2acn37","country_code":"US","type":"company","lineage":["https://openalex.org/I74786994"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D\u017eenan Zuki\u0107","raw_affiliation_strings":["Medical Computing Group, Kitware, Inc, Carrboro, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Computing Group, Kitware, Inc, Carrboro, NC, USA","institution_ids":["https://openalex.org/I74786994"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052901925","display_name":"Stefan Klein","orcid":"https://orcid.org/0000-0003-4449-6784"},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2801952686"]},{"id":"https://openalex.org/I913958620","display_name":"Erasmus University Rotterdam","ror":"https://ror.org/057w15z03","country_code":"NL","type":"education","lineage":["https://openalex.org/I913958620"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Stefan Klein","raw_affiliation_strings":["Biomedical Imaging Group Rotterdam, Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Imaging Group Rotterdam, Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I913958620","https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025788902","display_name":"Marius Staring","orcid":"https://orcid.org/0000-0003-2885-5812"},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Marius Staring","raw_affiliation_strings":["Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064472371","display_name":"Matthew McCormick","orcid":"https://orcid.org/0000-0001-9475-3756"},"institutions":[{"id":"https://openalex.org/I74786994","display_name":"Kitware (United States)","ror":"https://ror.org/02s2acn37","country_code":"US","type":"company","lineage":["https://openalex.org/I74786994"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew McCormick","raw_affiliation_strings":["Medical Computing Group, Kitware, Inc, Carrboro, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Computing Group, Kitware, Inc, Carrboro, NC, USA","institution_ids":["https://openalex.org/I74786994"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5025493773"],"corresponding_institution_ids":["https://openalex.org/I2800006345"],"apc_list":null,"apc_paid":null,"fwci":2.7117,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.92139283,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":null,"issue":null,"first_page":"101","last_page":"105"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11775","display_name":"COVID-19 diagnosis using AI","score":0.9588000178337097,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.8638020753860474},{"id":"https://openalex.org/keywords/image-registration","display_name":"Image registration","score":0.8474030494689941},{"id":"https://openalex.org/keywords/toolbox","display_name":"Toolbox","score":0.8148237466812134},{"id":"https://openalex.org/keywords/affine-transformation","display_name":"Affine transformation","score":0.7800641059875488},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7778325080871582},{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.706690788269043},{"id":"https://openalex.org/keywords/modular-design","display_name":"Modular design","score":0.7038334012031555},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5962088108062744},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5947648286819458},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.46016332507133484},{"id":"https://openalex.org/keywords/plug-in","display_name":"Plug-in","score":0.43373340368270874},{"id":"https://openalex.org/keywords/computer-graphics","display_name":"Computer graphics (images)","score":0.4313448667526245},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.38721275329589844},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.12491539120674133},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.09907308220863342},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.09134715795516968}],"concepts":[{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.8638020753860474},{"id":"https://openalex.org/C166704113","wikidata":"https://www.wikidata.org/wiki/Q861092","display_name":"Image registration","level":3,"score":0.8474030494689941},{"id":"https://openalex.org/C2777655017","wikidata":"https://www.wikidata.org/wiki/Q1501161","display_name":"Toolbox","level":2,"score":0.8148237466812134},{"id":"https://openalex.org/C92757383","wikidata":"https://www.wikidata.org/wiki/Q382497","display_name":"Affine transformation","level":2,"score":0.7800641059875488},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7778325080871582},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.706690788269043},{"id":"https://openalex.org/C101468663","wikidata":"https://www.wikidata.org/wiki/Q1620158","display_name":"Modular design","level":2,"score":0.7038334012031555},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5962088108062744},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5947648286819458},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.46016332507133484},{"id":"https://openalex.org/C4924752","wikidata":"https://www.wikidata.org/wiki/Q184148","display_name":"Plug-in","level":2,"score":0.43373340368270874},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.4313448667526245},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.38721275329589844},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.12491539120674133},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.09907308220863342},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.09134715795516968},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.25080/gerudo-f2bc6f59-00d","is_oa":true,"landing_page_url":"https://doi.org/10.25080/gerudo-f2bc6f59-00d","pdf_url":"https://conference.scipy.org/proceedings/scipy2023/pdfs/konstantinos_ntatsis.pdf","source":{"id":"https://openalex.org/S4220651651","display_name":"Proceedings of the Python in Science Conferences","issn_l":"2575-9752","issn":["2575-9752"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Python in Science Conference","raw_type":"proceedings-article"}],"best_oa_location":{"id":"doi:10.25080/gerudo-f2bc6f59-00d","is_oa":true,"landing_page_url":"https://doi.org/10.25080/gerudo-f2bc6f59-00d","pdf_url":"https://conference.scipy.org/proceedings/scipy2023/pdfs/konstantinos_ntatsis.pdf","source":{"id":"https://openalex.org/S4220651651","display_name":"Proceedings of the Python in Science Conferences","issn_l":"2575-9752","issn":["2575-9752"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Python in Science Conference","raw_type":"proceedings-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320315474","display_name":"Chan Zuckerberg Initiative","ror":"https://ror.org/02qenvm24"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4385894277.pdf"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1579634341","https://openalex.org/W1606938841","https://openalex.org/W1985586071","https://openalex.org/W2018919812","https://openalex.org/W2019836674","https://openalex.org/W2026616100","https://openalex.org/W2028911404","https://openalex.org/W2063815712","https://openalex.org/W2097110160","https://openalex.org/W2109115250","https://openalex.org/W2133287637","https://openalex.org/W2133584444","https://openalex.org/W2270820183","https://openalex.org/W2472803348","https://openalex.org/W2507987841","https://openalex.org/W3003257820","https://openalex.org/W3099878876","https://openalex.org/W3103145119","https://openalex.org/W4221155223","https://openalex.org/W4233882242","https://openalex.org/W4308610041","https://openalex.org/W6949831108","https://openalex.org/W6982728064"],"related_works":["https://openalex.org/W2940748022","https://openalex.org/W4385232743","https://openalex.org/W3209887338","https://openalex.org/W4287707351","https://openalex.org/W3085674040","https://openalex.org/W4296546738","https://openalex.org/W3045563283","https://openalex.org/W3163375306","https://openalex.org/W2024152175","https://openalex.org/W2536727263"],"abstract_inverted_index":{"Image":[0],"registration":[1,50,83],"plays":[2],"a":[3,21,42],"vital":[4],"role":[5],"in":[6,11,88],"understanding":[7],"changes":[8],"that":[9,24],"occur":[10],"2D":[12],"and":[13,58,80,85],"3D":[14],"scientific":[15],"imaging":[16,67],"datasets.":[17,68],"Registration":[18],"involves":[19],"finding":[20],"spatial":[22],"transformation":[23],"aligns":[25],"one":[26],"image":[27,33,89],"to":[28],"another":[29],"by":[30],"optimizing":[31],"relevant":[32],"similarity":[34],"metrics.":[35],"In":[36],"this":[37],"paper,":[38],"we":[39],"introduce":[40],"itk-elastix,":[41,75],"user-friendly":[43],"Python":[44],"wrapping":[45],"of":[46,74],"the":[47,71],"mature":[48],"elastix":[49],"toolbox.":[51],"The":[52],"open-source":[53],"tool":[54],"supports":[55],"rigid,":[56],"affine,":[57],"B-spline":[59],"deformable":[60],"registration,":[61],"making":[62],"it":[63],"versatile":[64],"for":[65],"various":[66],"By":[69],"utilizing":[70],"modular":[72],"design":[73],"users":[76],"can":[77],"efficiently":[78],"configure":[79],"compare":[81],"different":[82],"methods,":[84],"embed":[86],"these":[87],"analysis":[90],"workflows.":[91]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":2}],"updated_date":"2026-06-03T09:05:47.796612","created_date":"2025-10-10T00:00:00"}
