{"id":"https://openalex.org/W4382562090","doi":"https://doi.org/10.23919/mipro57284.2023.10159716","title":"Fortuna Detects Novel Splicing in Drosophila scRNASeq Data","display_name":"Fortuna Detects Novel Splicing in Drosophila scRNASeq Data","publication_year":2023,"publication_date":"2023-05-22","ids":{"openalex":"https://openalex.org/W4382562090","doi":"https://doi.org/10.23919/mipro57284.2023.10159716"},"language":"en","primary_location":{"id":"doi:10.23919/mipro57284.2023.10159716","is_oa":false,"landing_page_url":"http://dx.doi.org/10.23919/mipro57284.2023.10159716","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 46th MIPRO ICT and Electronics Convention (MIPRO)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032326611","display_name":"Bartol Borozan","orcid":null},"institutions":[{"id":"https://openalex.org/I51314090","display_name":"University of Osijek","ror":"https://ror.org/05sw4wc49","country_code":"HR","type":"education","lineage":["https://openalex.org/I51314090"]}],"countries":["HR"],"is_corresponding":true,"raw_author_name":"B. Borozan","raw_affiliation_strings":["University of Osijek,Department of mathematics,Osijek,Croatia","Department of mathematics, University of Osijek, Osijek, Croatia"],"affiliations":[{"raw_affiliation_string":"University of Osijek,Department of mathematics,Osijek,Croatia","institution_ids":["https://openalex.org/I51314090"]},{"raw_affiliation_string":"Department of mathematics, University of Osijek, Osijek, Croatia","institution_ids":["https://openalex.org/I51314090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038862875","display_name":"Luka Borozan","orcid":"https://orcid.org/0009-0001-4728-8481"},"institutions":[{"id":"https://openalex.org/I51314090","display_name":"University of Osijek","ror":"https://ror.org/05sw4wc49","country_code":"HR","type":"education","lineage":["https://openalex.org/I51314090"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"L. Borozan","raw_affiliation_strings":["University of Osijek,Department of mathematics,Osijek,Croatia","Department of mathematics, University of Osijek, Osijek, Croatia"],"affiliations":[{"raw_affiliation_string":"University of Osijek,Department of mathematics,Osijek,Croatia","institution_ids":["https://openalex.org/I51314090"]},{"raw_affiliation_string":"Department of mathematics, University of Osijek, Osijek, Croatia","institution_ids":["https://openalex.org/I51314090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063986948","display_name":"Domagoj \u0160everdija","orcid":"https://orcid.org/0000-0001-9501-1025"},"institutions":[{"id":"https://openalex.org/I51314090","display_name":"University of Osijek","ror":"https://ror.org/05sw4wc49","country_code":"HR","type":"education","lineage":["https://openalex.org/I51314090"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"D. \u0160everdija","raw_affiliation_strings":["University of Osijek,Department of mathematics,Osijek,Croatia","Department of mathematics, University of Osijek, Osijek, Croatia"],"affiliations":[{"raw_affiliation_string":"University of Osijek,Department of mathematics,Osijek,Croatia","institution_ids":["https://openalex.org/I51314090"]},{"raw_affiliation_string":"Department of mathematics, University of Osijek, Osijek, Croatia","institution_ids":["https://openalex.org/I51314090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036002844","display_name":"Domagoj Matijevi\u0107","orcid":"https://orcid.org/0000-0003-3390-9467"},"institutions":[{"id":"https://openalex.org/I51314090","display_name":"University of Osijek","ror":"https://ror.org/05sw4wc49","country_code":"HR","type":"education","lineage":["https://openalex.org/I51314090"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"D. Matijevi\u0107","raw_affiliation_strings":["University of Osijek,Department of mathematics,Osijek,Croatia","Department of mathematics, University of Osijek, Osijek, Croatia"],"affiliations":[{"raw_affiliation_string":"University of Osijek,Department of mathematics,Osijek,Croatia","institution_ids":["https://openalex.org/I51314090"]},{"raw_affiliation_string":"Department of mathematics, University of Osijek, Osijek, Croatia","institution_ids":["https://openalex.org/I51314090"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055704933","display_name":"Stefan Canzar","orcid":"https://orcid.org/0000-0003-4719-8010"},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Canzar","raw_affiliation_strings":["Pennsylvania State University, University Park,Department of Computer Science and Engineering,PA,USA","Department of Computer Science and Engineering, Pennsylvania State University, University Park, PA, USA"],"affiliations":[{"raw_affiliation_string":"Pennsylvania State University, University Park,Department of Computer Science and Engineering,PA,USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, Pennsylvania State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5032326611"],"corresponding_institution_ids":["https://openalex.org/I51314090"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.25932172,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"410","last_page":"415"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9950000047683716,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drosophila-melanogaster","display_name":"Drosophila melanogaster","score":0.6757907271385193},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.6500197649002075},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.554054856300354},{"id":"https://openalex.org/keywords/rna-splicing","display_name":"RNA splicing","score":0.5337309241294861},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5048473477363586},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4970300495624542},{"id":"https://openalex.org/keywords/drosophila","display_name":"Drosophila (subgenus)","score":0.4935213327407837},{"id":"https://openalex.org/keywords/intron","display_name":"Intron","score":0.434139609336853},{"id":"https://openalex.org/keywords/on-the-fly","display_name":"On the fly","score":0.4197264611721039},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3170455992221832},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.3140655755996704},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.15956330299377441}],"concepts":[{"id":"https://openalex.org/C2780104201","wikidata":"https://www.wikidata.org/wiki/Q130888","display_name":"Drosophila melanogaster","level":3,"score":0.6757907271385193},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.6500197649002075},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.554054856300354},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.5337309241294861},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5048473477363586},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4970300495624542},{"id":"https://openalex.org/C2776041557","wikidata":"https://www.wikidata.org/wiki/Q3715451","display_name":"Drosophila (subgenus)","level":3,"score":0.4935213327407837},{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.434139609336853},{"id":"https://openalex.org/C2781020372","wikidata":"https://www.wikidata.org/wiki/Q533093","display_name":"On the fly","level":2,"score":0.4197264611721039},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3170455992221832},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.3140655755996704},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15956330299377441},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.23919/mipro57284.2023.10159716","is_oa":false,"landing_page_url":"http://dx.doi.org/10.23919/mipro57284.2023.10159716","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 46th MIPRO ICT and Electronics Convention (MIPRO)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W70742678","https://openalex.org/W1989762673","https://openalex.org/W2011920499","https://openalex.org/W2013340095","https://openalex.org/W2108234281","https://openalex.org/W2140729960","https://openalex.org/W2155804510","https://openalex.org/W2169456326","https://openalex.org/W2267092331","https://openalex.org/W2323326409","https://openalex.org/W2592811885","https://openalex.org/W2800410670","https://openalex.org/W2887117829","https://openalex.org/W2909194804","https://openalex.org/W2951506174","https://openalex.org/W2964849163","https://openalex.org/W3042475334","https://openalex.org/W4214861448","https://openalex.org/W4280598116","https://openalex.org/W4383873231","https://openalex.org/W6602827161","https://openalex.org/W6799580545","https://openalex.org/W6854556209"],"related_works":["https://openalex.org/W2018569889","https://openalex.org/W4236915199","https://openalex.org/W4238688176","https://openalex.org/W2078833601","https://openalex.org/W2004898077","https://openalex.org/W1986280646","https://openalex.org/W2163285239","https://openalex.org/W2054641857","https://openalex.org/W4235196958","https://openalex.org/W1991679818"],"abstract_inverted_index":{"Recent":[0],"developments":[1],"in":[2,38,120],"single-cell":[3,147],"RNA":[4],"sequencing":[5],"techniques":[6],"(scRNASeq)":[7],"have":[8],"made":[9],"large":[10],"quantities":[11],"of":[12,24,42,109,124,133],"sequenced":[13],"data":[14,61,148],"available":[15],"across":[16],"numerous":[17],"species":[18,132],"and":[19,30,34,93,114],"tissues.":[20],"Alternative":[21],"splicing":[22,117],"(AS)":[23],"pre-mRNA":[25],"introns":[26],"varies":[27],"between":[28,32],"tissues":[29],"even":[31],"cell-types":[33],"can":[35],"be":[36],"altered":[37],"disease.":[39],"The":[40],"study":[41],"novel":[43,83,95],"AS,":[44],"using":[45],"standard":[46],"RNASeq":[47],"data,":[48],"has":[49,62],"been":[50,63],"extensively":[51],"studied":[52],"for":[53],"many":[54],"years,":[55],"while":[56],"similar":[57,119],"work":[58],"on":[59,144],"scRNASeq":[60,100],"scarce,":[64],"despite":[65],"its":[66,104],"potential":[67],"to":[68,98,103,122,136],"offer":[69],"a":[70,82,88,131],"broader":[71],"insight":[72],"into":[73],"cell-type":[74],"specific":[75],"processes.":[76],"In":[77],"this":[78],"paper,":[79],"we":[80,139],"propose":[81],"pipeline":[84,143],"that":[85,90],"uses":[86],"fortuna,":[87],"method":[89],"efficiently":[91],"classifies":[92],"quantifies":[94],"AS":[96],"events,":[97],"process":[99],"samples.":[101],"Due":[102],"short":[105],"lifespan,":[106],"high":[107],"number":[108],"progeny,":[110],"low":[111],"maintenance":[112],"cost,":[113],"intricate":[115],"alternative":[116],"patterns":[118],"complexity":[121],"those":[123],"mammals,":[125],"Drosophila":[126,146],"Melanogaster":[127],"(fruit":[128],"fly)":[129],"is":[130],"particular":[134],"interest":[135],"researchers.":[137],"Therefore,":[138],"experimentally":[140],"evaluate":[141],"our":[142],"real-world":[145],"samples":[149],"from":[150],"the":[151],"Fly":[152],"Cell":[153],"Atlas.":[154]},"counts_by_year":[],"updated_date":"2025-12-24T23:09:58.560324","created_date":"2025-10-10T00:00:00"}