{"id":"https://openalex.org/W4387489389","doi":"https://doi.org/10.23919/spa59660.2023.10274460","title":"Synthetic Image Generation With a Fine-Tuned Latent Diffusion Model for Organ on Chip Cell Image Classification","display_name":"Synthetic Image Generation With a Fine-Tuned Latent Diffusion Model for Organ on Chip Cell Image Classification","publication_year":2023,"publication_date":"2023-09-20","ids":{"openalex":"https://openalex.org/W4387489389","doi":"https://doi.org/10.23919/spa59660.2023.10274460"},"language":"en","primary_location":{"id":"doi:10.23919/spa59660.2023.10274460","is_oa":false,"landing_page_url":"https://doi.org/10.23919/spa59660.2023.10274460","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 Signal Processing: Algorithms, Architectures, Arrangements, and Applications (SPA)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013367714","display_name":"Maksims Ivanovs","orcid":"https://orcid.org/0000-0003-2477-7327"},"institutions":[{"id":"https://openalex.org/I4210162447","display_name":"Institute of Electronics and Computer Science","ror":"https://ror.org/05bsp2531","country_code":"LV","type":"facility","lineage":["https://openalex.org/I4210162447","https://openalex.org/I70055295"]}],"countries":["LV"],"is_corresponding":true,"raw_author_name":"Maksims Ivanovs","raw_affiliation_strings":["Institute of Electronics and Computer Science,Riga,Latvia","Institute of Electronics and Computer Science, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Institute of Electronics and Computer Science,Riga,Latvia","institution_ids":["https://openalex.org/I4210162447"]},{"raw_affiliation_string":"Institute of Electronics and Computer Science, Riga, Latvia","institution_ids":["https://openalex.org/I4210162447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012019325","display_name":"Laura Leja","orcid":null},"institutions":[{"id":"https://openalex.org/I4210162447","display_name":"Institute of Electronics and Computer Science","ror":"https://ror.org/05bsp2531","country_code":"LV","type":"facility","lineage":["https://openalex.org/I4210162447","https://openalex.org/I70055295"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Laura Leja","raw_affiliation_strings":["Institute of Electronics and Computer Science,Riga,Latvia","Institute of Electronics and Computer Science, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Institute of Electronics and Computer Science,Riga,Latvia","institution_ids":["https://openalex.org/I4210162447"]},{"raw_affiliation_string":"Institute of Electronics and Computer Science, Riga, Latvia","institution_ids":["https://openalex.org/I4210162447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093034427","display_name":"K\u0101rlis Gustavs Zviedris","orcid":null},"institutions":[{"id":"https://openalex.org/I4210162447","display_name":"Institute of Electronics and Computer Science","ror":"https://ror.org/05bsp2531","country_code":"LV","type":"facility","lineage":["https://openalex.org/I4210162447","https://openalex.org/I70055295"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"K\u0101rlis Zviedris","raw_affiliation_strings":["Institute of Electronics and Computer Science,Riga,Latvia","Institute of Electronics and Computer Science, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Institute of Electronics and Computer Science,Riga,Latvia","institution_ids":["https://openalex.org/I4210162447"]},{"raw_affiliation_string":"Institute of Electronics and Computer Science, Riga, Latvia","institution_ids":["https://openalex.org/I4210162447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089552837","display_name":"Roberts Rim\u0161a","orcid":"https://orcid.org/0000-0002-8915-5361"},"institutions":[{"id":"https://openalex.org/I91123046","display_name":"University of Latvia","ror":"https://ror.org/05g3mes96","country_code":"LV","type":"education","lineage":["https://openalex.org/I91123046"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Roberts Rimsa","raw_affiliation_strings":["Cellbox Labs,Riga,Latvia","Cellbox Labs, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Cellbox Labs,Riga,Latvia","institution_ids":["https://openalex.org/I91123046"]},{"raw_affiliation_string":"Cellbox Labs, Riga, Latvia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017338915","display_name":"Kar\u012bna Narbute","orcid":"https://orcid.org/0000-0002-5358-6194"},"institutions":[{"id":"https://openalex.org/I141777705","display_name":"Latvian Biomedical Research and Study Centre","ror":"https://ror.org/01gckhp53","country_code":"LV","type":"facility","lineage":["https://openalex.org/I141777705"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Karina Narbute","raw_affiliation_strings":["Latvian Biomedical Research and Study Centre,Riga,Latvia","Latvian Biomedical Research and Study Centre, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre,Riga,Latvia","institution_ids":["https://openalex.org/I141777705"]},{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre, Riga, Latvia","institution_ids":["https://openalex.org/I141777705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093034428","display_name":"Val\u0113rija Mov\u010dana","orcid":"https://orcid.org/0009-0001-7234-9100"},"institutions":[{"id":"https://openalex.org/I141777705","display_name":"Latvian Biomedical Research and Study Centre","ror":"https://ror.org/01gckhp53","country_code":"LV","type":"facility","lineage":["https://openalex.org/I141777705"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Valerija Movcana","raw_affiliation_strings":["Latvian Biomedical Research and Study Centre,Riga,Latvia","Latvian Biomedical Research and Study Centre, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre,Riga,Latvia","institution_ids":["https://openalex.org/I141777705"]},{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre, Riga, Latvia","institution_ids":["https://openalex.org/I141777705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058521240","display_name":"F\u0113likss R\u016bmnieks","orcid":"https://orcid.org/0000-0003-3745-3575"},"institutions":[{"id":"https://openalex.org/I141777705","display_name":"Latvian Biomedical Research and Study Centre","ror":"https://ror.org/01gckhp53","country_code":"LV","type":"facility","lineage":["https://openalex.org/I141777705"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Felikss Rumnieks","raw_affiliation_strings":["Latvian Biomedical Research and Study Centre,Riga,Latvia","Latvian Biomedical Research and Study Centre, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre,Riga,Latvia","institution_ids":["https://openalex.org/I141777705"]},{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre, Riga, Latvia","institution_ids":["https://openalex.org/I141777705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051603181","display_name":"Arnis Strods","orcid":"https://orcid.org/0000-0002-6550-2605"},"institutions":[{"id":"https://openalex.org/I141777705","display_name":"Latvian Biomedical Research and Study Centre","ror":"https://ror.org/01gckhp53","country_code":"LV","type":"facility","lineage":["https://openalex.org/I141777705"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Arnis Strods","raw_affiliation_strings":["Latvian Biomedical Research and Study Centre,Riga,Latvia","Latvian Biomedical Research and Study Centre, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre,Riga,Latvia","institution_ids":["https://openalex.org/I141777705"]},{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre, Riga, Latvia","institution_ids":["https://openalex.org/I141777705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093034429","display_name":"K\u00e9vin Gillois","orcid":null},"institutions":[{"id":"https://openalex.org/I141777705","display_name":"Latvian Biomedical Research and Study Centre","ror":"https://ror.org/01gckhp53","country_code":"LV","type":"facility","lineage":["https://openalex.org/I141777705"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Kevin Gillois","raw_affiliation_strings":["Latvian Biomedical Research and Study Centre,Riga,Latvia","Latvian Biomedical Research and Study Centre, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre,Riga,Latvia","institution_ids":["https://openalex.org/I141777705"]},{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre, Riga, Latvia","institution_ids":["https://openalex.org/I141777705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081500939","display_name":"Gatis Mozo\u013cevskis","orcid":"https://orcid.org/0000-0001-7418-9123"},"institutions":[{"id":"https://openalex.org/I91123046","display_name":"University of Latvia","ror":"https://ror.org/05g3mes96","country_code":"LV","type":"education","lineage":["https://openalex.org/I91123046"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Gatis Mozolevskis","raw_affiliation_strings":["Cellbox Labs,Riga,Latvia","Cellbox Labs, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Cellbox Labs,Riga,Latvia","institution_ids":["https://openalex.org/I91123046"]},{"raw_affiliation_string":"Cellbox Labs, Riga, Latvia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088401493","display_name":"Art\u016brs \u0100bols","orcid":null},"institutions":[{"id":"https://openalex.org/I91123046","display_name":"University of Latvia","ror":"https://ror.org/05g3mes96","country_code":"LV","type":"education","lineage":["https://openalex.org/I91123046"]},{"id":"https://openalex.org/I141777705","display_name":"Latvian Biomedical Research and Study Centre","ror":"https://ror.org/01gckhp53","country_code":"LV","type":"facility","lineage":["https://openalex.org/I141777705"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Arturs Abols","raw_affiliation_strings":["Cellbox Labs,Riga,Latvia","Cellbox Labs, Riga, Latvia","Latvian Biomedical Research and Study Centre, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Cellbox Labs,Riga,Latvia","institution_ids":["https://openalex.org/I91123046"]},{"raw_affiliation_string":"Cellbox Labs, Riga, Latvia","institution_ids":[]},{"raw_affiliation_string":"Latvian Biomedical Research and Study Centre, Riga, Latvia","institution_ids":["https://openalex.org/I141777705"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073394716","display_name":"Roberts Kadi\u0137is","orcid":"https://orcid.org/0000-0001-6845-4381"},"institutions":[{"id":"https://openalex.org/I4210162447","display_name":"Institute of Electronics and Computer Science","ror":"https://ror.org/05bsp2531","country_code":"LV","type":"facility","lineage":["https://openalex.org/I4210162447","https://openalex.org/I70055295"]}],"countries":["LV"],"is_corresponding":false,"raw_author_name":"Roberts Kadikis","raw_affiliation_strings":["Institute of Electronics and Computer Science,Riga,Latvia","Institute of Electronics and Computer Science, Riga, Latvia"],"affiliations":[{"raw_affiliation_string":"Institute of Electronics and Computer Science,Riga,Latvia","institution_ids":["https://openalex.org/I4210162447"]},{"raw_affiliation_string":"Institute of Electronics and Computer Science, Riga, Latvia","institution_ids":["https://openalex.org/I4210162447"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5013367714"],"corresponding_institution_ids":["https://openalex.org/I4210162447"],"apc_list":null,"apc_paid":null,"fwci":1.0983,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.84240216,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"148","last_page":"153"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10775","display_name":"Generative Adversarial Networks and Image Synthesis","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7537041306495667},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6726282835006714},{"id":"https://openalex.org/keywords/adaptation","display_name":"Adaptation (eye)","score":0.6479968428611755},{"id":"https://openalex.org/keywords/synthetic-data","display_name":"Synthetic data","score":0.6095110177993774},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.6041359901428223},{"id":"https://openalex.org/keywords/rank","display_name":"Rank (graph theory)","score":0.5991179943084717},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5322988033294678},{"id":"https://openalex.org/keywords/data-modeling","display_name":"Data modeling","score":0.4970903694629669},{"id":"https://openalex.org/keywords/diffusion","display_name":"Diffusion","score":0.46713757514953613},{"id":"https://openalex.org/keywords/training-set","display_name":"Training set","score":0.4579225480556488},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.4538908004760742},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3490495979785919},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.33447587490081787},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.32317379117012024},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.09180572628974915},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.09098458290100098}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7537041306495667},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6726282835006714},{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.6479968428611755},{"id":"https://openalex.org/C160920958","wikidata":"https://www.wikidata.org/wiki/Q7662746","display_name":"Synthetic data","level":2,"score":0.6095110177993774},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.6041359901428223},{"id":"https://openalex.org/C164226766","wikidata":"https://www.wikidata.org/wiki/Q7293202","display_name":"Rank (graph theory)","level":2,"score":0.5991179943084717},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5322988033294678},{"id":"https://openalex.org/C67186912","wikidata":"https://www.wikidata.org/wiki/Q367664","display_name":"Data modeling","level":2,"score":0.4970903694629669},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.46713757514953613},{"id":"https://openalex.org/C51632099","wikidata":"https://www.wikidata.org/wiki/Q3985153","display_name":"Training set","level":2,"score":0.4579225480556488},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.4538908004760742},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3490495979785919},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.33447587490081787},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.32317379117012024},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.09180572628974915},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.09098458290100098},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.23919/spa59660.2023.10274460","is_oa":false,"landing_page_url":"https://doi.org/10.23919/spa59660.2023.10274460","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 Signal Processing: Algorithms, Architectures, Arrangements, and Applications (SPA)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1861492603","https://openalex.org/W1959608418","https://openalex.org/W2108598243","https://openalex.org/W2129069237","https://openalex.org/W2755577605","https://openalex.org/W2893531431","https://openalex.org/W2918598741","https://openalex.org/W2955425717","https://openalex.org/W2964168257","https://openalex.org/W2975317124","https://openalex.org/W3013589844","https://openalex.org/W3036167779","https://openalex.org/W3043188797","https://openalex.org/W3100819185","https://openalex.org/W3129576130","https://openalex.org/W3138791055","https://openalex.org/W3168053944","https://openalex.org/W3168867926","https://openalex.org/W3186197713","https://openalex.org/W4223899585","https://openalex.org/W4285029380","https://openalex.org/W4285819920","https://openalex.org/W4286642328","https://openalex.org/W4298289240","https://openalex.org/W4312933868","https://openalex.org/W4321504560","https://openalex.org/W6637568146","https://openalex.org/W6639102338","https://openalex.org/W6738543193","https://openalex.org/W6747888389","https://openalex.org/W6762718338","https://openalex.org/W6779823529","https://openalex.org/W6788990321","https://openalex.org/W6790978476"],"related_works":["https://openalex.org/W4312659495","https://openalex.org/W3175965105","https://openalex.org/W4385366257","https://openalex.org/W3101007570","https://openalex.org/W4387910575","https://openalex.org/W3109499659","https://openalex.org/W3091312527","https://openalex.org/W1555087354","https://openalex.org/W4287865546","https://openalex.org/W3007306981"],"abstract_inverted_index":{"Augmentation":[0],"of":[1,4,18,22,48,57,60,100,113,120,123,128,136,148,155],"the":[2,16,19,34,58,66,74,79,89,95,101,118,121,124,137,146,153],"datasets":[3],"authentic":[5,75],"microscopy":[6],"images":[7,10,59,69,76],"with":[8,104],"synthetic":[9,68,96],"is":[11,141],"a":[12,39,54,133],"promising":[13],"solution":[14],"to":[15,52,73,117,143],"problem":[17],"limited":[20],"availability":[21],"biomedical":[23,156],"data":[24,97,115],"for":[25,152],"training":[26,88],"deep":[27],"neural":[28],"network":[29],"(DNN)":[30],"based":[31],"classifiers.":[32],"In":[33],"present":[35],"study,":[36],"we":[37,84],"use":[38,145],"text-to-image":[40],"latent":[41,149],"stable":[42],"diffusion":[43,150],"model":[44,92],"fine-tuned":[45],"by":[46],"means":[47],"low-rank":[49,80,138],"adaptation":[50,81,139],"(LoRA)":[51],"augment":[53],"small":[55],"dataset":[56,103],"organ":[61],"on":[62,77,94],"chip":[63],"cells.":[64],"While":[65],"resulting":[67],"appear":[70],"quite":[71],"similar":[72],"which":[78],"was":[82],"performed,":[83],"find":[85],"that":[86,132],"neither":[87],"EfficientNetB7":[90],"DNN":[91],"solely":[93],"nor":[98],"augmentation":[99],"real-world":[102],"different":[105],"proportions":[106],"(10,":[107],"25,":[108],"50,":[109],"and":[110],"75":[111],"percent)":[112],"these":[114],"leads":[116],"improvement":[119],"accuracy":[122],"model.":[125],"The":[126],"findings":[127],"our":[129],"study":[130],"suggest":[131],"further":[134],"exploration":[135],"options":[140],"needed":[142],"fully":[144],"capacity":[147],"models":[151],"synthesis":[154],"images.":[157]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}