{"id":"https://openalex.org/W2898328971","doi":"https://doi.org/10.23919/iconac.2018.8748972","title":"SNPs-based Hypertension Disease Detection via Machine Learning Techniques","display_name":"SNPs-based Hypertension Disease Detection via Machine Learning Techniques","publication_year":2018,"publication_date":"2018-09-01","ids":{"openalex":"https://openalex.org/W2898328971","doi":"https://doi.org/10.23919/iconac.2018.8748972","mag":"2898328971"},"language":"en","primary_location":{"id":"doi:10.23919/iconac.2018.8748972","is_oa":false,"landing_page_url":"https://doi.org/10.23919/iconac.2018.8748972","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 24th International Conference on Automation and Computing (ICAC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://durham-repository.worktribe.com/output/1140421","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040647752","display_name":"Raid Alzubi","orcid":"https://orcid.org/0000-0002-6651-8342"},"institutions":[{"id":"https://openalex.org/I868834043","display_name":"University of the West of Scotland","ror":"https://ror.org/04w3d2v20","country_code":"GB","type":"education","lineage":["https://openalex.org/I868834043"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Raid Alzubi","raw_affiliation_strings":["School of Engineering and Computing, University of the West of Scotland, Paisley, United Kingdom"],"affiliations":[{"raw_affiliation_string":"School of Engineering and Computing, University of the West of Scotland, Paisley, United Kingdom","institution_ids":["https://openalex.org/I868834043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080291510","display_name":"Naeem Ramzan","orcid":"https://orcid.org/0000-0002-5088-1462"},"institutions":[{"id":"https://openalex.org/I868834043","display_name":"University of the West of Scotland","ror":"https://ror.org/04w3d2v20","country_code":"GB","type":"education","lineage":["https://openalex.org/I868834043"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Naeem Ramzan","raw_affiliation_strings":["School of Engineering and Computing, University of the West of Scotland, Paisley, United Kingdom"],"affiliations":[{"raw_affiliation_string":"School of Engineering and Computing, University of the West of Scotland, Paisley, United Kingdom","institution_ids":["https://openalex.org/I868834043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013434100","display_name":"Hadeel Alzoubi","orcid":"https://orcid.org/0000-0002-0846-4075"},"institutions":[{"id":"https://openalex.org/I868834043","display_name":"University of the West of Scotland","ror":"https://ror.org/04w3d2v20","country_code":"GB","type":"education","lineage":["https://openalex.org/I868834043"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hadeel Alzoubi","raw_affiliation_strings":["School of Engineering and Computing, University of the West of Scotland, Paisley, United Kingdom"],"affiliations":[{"raw_affiliation_string":"School of Engineering and Computing, University of the West of Scotland, Paisley, United Kingdom","institution_ids":["https://openalex.org/I868834043"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005052027","display_name":"Stamos Katsigiannis","orcid":"https://orcid.org/0000-0001-9190-0941"},"institutions":[{"id":"https://openalex.org/I868834043","display_name":"University of the West of Scotland","ror":"https://ror.org/04w3d2v20","country_code":"GB","type":"education","lineage":["https://openalex.org/I868834043"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stamos Katsigiannis","raw_affiliation_strings":["School of Engineering and Computing, University of the West of Scotland, Paisley, United Kingdom"],"affiliations":[{"raw_affiliation_string":"School of Engineering and Computing, University of the West of Scotland, Paisley, United Kingdom","institution_ids":["https://openalex.org/I868834043"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5040647752"],"corresponding_institution_ids":["https://openalex.org/I868834043"],"apc_list":null,"apc_paid":null,"fwci":0.2758,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.57312209,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.97079998254776,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9674000144004822,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.7492244839668274},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7330955862998962},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.653501033782959},{"id":"https://openalex.org/keywords/naive-bayes-classifier","display_name":"Naive Bayes classifier","score":0.6066495776176453},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5706465840339661},{"id":"https://openalex.org/keywords/linear-discriminant-analysis","display_name":"Linear discriminant analysis","score":0.5579313635826111},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.49474188685417175},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.475063294172287},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.4404502213001251},{"id":"https://openalex.org/keywords/statistical-classification","display_name":"Statistical classification","score":0.4280582666397095},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.09586003422737122},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.09428966045379639},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.0836523175239563}],"concepts":[{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.7492244839668274},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7330955862998962},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.653501033782959},{"id":"https://openalex.org/C52001869","wikidata":"https://www.wikidata.org/wiki/Q812530","display_name":"Naive Bayes classifier","level":3,"score":0.6066495776176453},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5706465840339661},{"id":"https://openalex.org/C69738355","wikidata":"https://www.wikidata.org/wiki/Q1228929","display_name":"Linear discriminant analysis","level":2,"score":0.5579313635826111},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.49474188685417175},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.475063294172287},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.4404502213001251},{"id":"https://openalex.org/C110083411","wikidata":"https://www.wikidata.org/wiki/Q1744628","display_name":"Statistical classification","level":2,"score":0.4280582666397095},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09586003422737122},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09428966045379639},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0836523175239563},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.23919/iconac.2018.8748972","is_oa":false,"landing_page_url":"https://doi.org/10.23919/iconac.2018.8748972","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 24th International Conference on Automation and Computing (ICAC)","raw_type":"proceedings-article"},{"id":"pmh:oai:durham-repository.worktribe.com:1140421","is_oa":true,"landing_page_url":"https://durham-repository.worktribe.com/output/1140421","pdf_url":null,"source":{"id":"https://openalex.org/S4306400188","display_name":"Durham Research Online (Durham University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I190082696","host_organization_name":"Durham University","host_organization_lineage":["https://openalex.org/I190082696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Presentation / Conference Contribution"}],"best_oa_location":{"id":"pmh:oai:durham-repository.worktribe.com:1140421","is_oa":true,"landing_page_url":"https://durham-repository.worktribe.com/output/1140421","pdf_url":null,"source":{"id":"https://openalex.org/S4306400188","display_name":"Durham Research Online (Durham University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I190082696","host_organization_name":"Durham University","host_organization_lineage":["https://openalex.org/I190082696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Presentation / Conference Contribution"},"sustainable_development_goals":[{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.6800000071525574}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1437423","https://openalex.org/W1658688950","https://openalex.org/W1802506671","https://openalex.org/W1963700405","https://openalex.org/W1986913015","https://openalex.org/W2042308063","https://openalex.org/W2078133899","https://openalex.org/W2085039669","https://openalex.org/W2112917490","https://openalex.org/W2119387367","https://openalex.org/W2121514846","https://openalex.org/W2126009609","https://openalex.org/W2134783591","https://openalex.org/W2142594886","https://openalex.org/W2149454242","https://openalex.org/W2150825072","https://openalex.org/W2153127576","https://openalex.org/W2156504490","https://openalex.org/W2213087239","https://openalex.org/W2277388844","https://openalex.org/W2324255546","https://openalex.org/W2420474086","https://openalex.org/W2551994708","https://openalex.org/W2552381855","https://openalex.org/W2554948173","https://openalex.org/W2558077163","https://openalex.org/W2598903256","https://openalex.org/W2762503377","https://openalex.org/W2770646541","https://openalex.org/W2997674406","https://openalex.org/W6682686508","https://openalex.org/W6730318000"],"related_works":["https://openalex.org/W2086889680","https://openalex.org/W4246466849","https://openalex.org/W3153505674","https://openalex.org/W2997511728","https://openalex.org/W2998259334","https://openalex.org/W4381745996","https://openalex.org/W2119349310","https://openalex.org/W2995276271","https://openalex.org/W4312478656","https://openalex.org/W3168126470"],"abstract_inverted_index":{"Machine":[0],"learning":[1],"and":[2,57,120,157,166],"data":[3],"mining":[4],"techniques":[5,49],"have":[6,41,50,102],"recently":[7],"gained":[8],"more":[9],"popularity":[10],"in":[11,74,88],"the":[12,19,22,27,81,94,141,150,154,161,171,174,178],"field":[13],"of":[14,21,26,31,60,80,96,140,173,180],"Medical":[15],"diagnosis,":[16],"especially":[17],"for":[18,53,93,177],"analysis":[20],"human":[23,32,46],"genome.":[24],"One":[25],"most":[28,82],"significant":[29],"sources":[30],"genome":[33],"variation":[34],"is":[35],"Single":[36],"Nucleotide":[37],"Polymorphisms":[38],"(SNPs),":[39],"which":[40],"been":[42,51,72,103],"associated":[43],"with":[44,89,126],"multiple":[45],"diseases.":[47],"Several":[48],"developed":[52],"distinguishing":[54],"between":[55],"affected":[56],"healthy":[58],"samples":[59],"SNP":[61],"data.":[62,185],"In":[63],"this":[64],"study,":[65],"conditional":[66],"mutual":[67],"information":[68],"maximisation":[69],"(CMIM)":[70],"has":[71],"employed":[73],"order":[75],"to":[76,85],"identify":[77],"a":[78],"subset":[79],"informative":[83],"SNPs":[84,184],"be":[86],"used":[87],"various":[90],"classifications":[91],"algorithms":[92,101],"detection":[95,179],"hypertension":[97,181],"disease.":[98],"Five":[99],"classification":[100,135,146,163],"evaluated,":[104],"namely":[105],"k-Nearest":[106],"Neighbours":[107],"(KNN),":[108],"Artificial":[109],"Neural":[110],"Networks":[111],"(ANN),":[112],"Naive":[113],"Bayes":[114],"(NB),":[115],"Linear":[116],"Discriminant":[117],"Analysis":[118],"(LDA)":[119],"Support":[121],"Vector":[122],"Machines":[123],"(SVM),":[124],"along":[125],"their":[127],"combination":[128],"into":[129],"an":[130],"unweighted":[131],"majority":[132],"voting":[133],"ensemble":[134,151],"scheme.":[136],"The":[137],"experimental":[138],"evaluation":[139],"proposed":[142,175],"approach":[143,152,176],"via":[144],"supervised":[145],"experiments":[147],"showed":[148],"that":[149],"using":[153],"SVM,":[155],"5-NN,":[156],"NB":[158],"classifiers":[159],"achieves":[160],"highest":[162],"accuracy":[164],"(93.21%)":[165],"F1":[167],"score":[168],"(91.72%),":[169],"demonstrating":[170],"suitability":[172],"disease":[182],"from":[183]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}