{"id":"https://openalex.org/W1750115510","doi":"https://doi.org/10.23919/ecc.2013.6669467","title":"State estimation for gene networks with intrinsic and extrinsic noise: A case study on E.coli arabinose uptake dynamics","display_name":"State estimation for gene networks with intrinsic and extrinsic noise: A case study on E.coli arabinose uptake dynamics","publication_year":2013,"publication_date":"2013-07-01","ids":{"openalex":"https://openalex.org/W1750115510","doi":"https://doi.org/10.23919/ecc.2013.6669467","mag":"1750115510"},"language":"en","primary_location":{"id":"doi:10.23919/ecc.2013.6669467","is_oa":false,"landing_page_url":"https://doi.org/10.23919/ecc.2013.6669467","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 European Control Conference (ECC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079628168","display_name":"Alfonso Carta","orcid":null},"institutions":[{"id":"https://openalex.org/I1326498283","display_name":"Institut national de recherche en informatique et en automatique","ror":"https://ror.org/02kvxyf05","country_code":"FR","type":"funder","lineage":["https://openalex.org/I1326498283"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Alfonso Carta","raw_affiliation_strings":["BIOCORE, Inria Sophia-Antipolis, France","Team BIOCORE, BIOCORE at Inria Sophia-Antipolis, Sophia-Antipolis, France"],"affiliations":[{"raw_affiliation_string":"BIOCORE, Inria Sophia-Antipolis, France","institution_ids":["https://openalex.org/I1326498283"]},{"raw_affiliation_string":"Team BIOCORE, BIOCORE at Inria Sophia-Antipolis, Sophia-Antipolis, France","institution_ids":["https://openalex.org/I1326498283"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010375183","display_name":"Eugenio Cinquemani","orcid":"https://orcid.org/0000-0003-3353-6525"},"institutions":[{"id":"https://openalex.org/I1326498283","display_name":"Institut national de recherche en informatique et en automatique","ror":"https://ror.org/02kvxyf05","country_code":"FR","type":"funder","lineage":["https://openalex.org/I1326498283"]},{"id":"https://openalex.org/I899635006","display_name":"Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/02rx3b187","country_code":"FR","type":"education","lineage":["https://openalex.org/I899635006"]},{"id":"https://openalex.org/I4210101348","display_name":"Centre Inria de l'Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/00n8d6z93","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1326498283","https://openalex.org/I4210101348"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Eugenio Cinquemani","raw_affiliation_strings":["IBIS, Inria - Grenoble Rh\u00f4ne-Alpes, France","IBIS, Inria, Grenoble, France"],"affiliations":[{"raw_affiliation_string":"IBIS, Inria - Grenoble Rh\u00f4ne-Alpes, France","institution_ids":["https://openalex.org/I1326498283","https://openalex.org/I4210101348","https://openalex.org/I899635006"]},{"raw_affiliation_string":"IBIS, Inria, Grenoble, France","institution_ids":["https://openalex.org/I1326498283","https://openalex.org/I4210101348"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5079628168"],"corresponding_institution_ids":["https://openalex.org/I1326498283"],"apc_list":null,"apc_paid":null,"fwci":0.2995,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.60625823,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"3658","last_page":"3663"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kalman-filter","display_name":"Kalman filter","score":0.7298346757888794},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.6339606046676636},{"id":"https://openalex.org/keywords/stochastic-differential-equation","display_name":"Stochastic differential equation","score":0.5943102836608887},{"id":"https://openalex.org/keywords/particle-filter","display_name":"Particle filter","score":0.533256471157074},{"id":"https://openalex.org/keywords/stochastic-process","display_name":"Stochastic process","score":0.5309471487998962},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4959307610988617},{"id":"https://openalex.org/keywords/filter","display_name":"Filter (signal processing)","score":0.4276294410228729},{"id":"https://openalex.org/keywords/estimation-theory","display_name":"Estimation theory","score":0.41334718465805054},{"id":"https://openalex.org/keywords/control-theory","display_name":"Control theory (sociology)","score":0.3970036208629608},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.38983413577079773},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.349836140871048},{"id":"https://openalex.org/keywords/applied-mathematics","display_name":"Applied mathematics","score":0.31992197036743164},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.26451215147972107},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.23560887575149536},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.19122380018234253},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.14711475372314453},{"id":"https://openalex.org/keywords/control","display_name":"Control (management)","score":0.11361613869667053}],"concepts":[{"id":"https://openalex.org/C157286648","wikidata":"https://www.wikidata.org/wiki/Q846780","display_name":"Kalman filter","level":2,"score":0.7298346757888794},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.6339606046676636},{"id":"https://openalex.org/C51955184","wikidata":"https://www.wikidata.org/wiki/Q1545585","display_name":"Stochastic differential equation","level":2,"score":0.5943102836608887},{"id":"https://openalex.org/C52421305","wikidata":"https://www.wikidata.org/wiki/Q1151499","display_name":"Particle filter","level":3,"score":0.533256471157074},{"id":"https://openalex.org/C8272713","wikidata":"https://www.wikidata.org/wiki/Q176737","display_name":"Stochastic process","level":2,"score":0.5309471487998962},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4959307610988617},{"id":"https://openalex.org/C106131492","wikidata":"https://www.wikidata.org/wiki/Q3072260","display_name":"Filter (signal processing)","level":2,"score":0.4276294410228729},{"id":"https://openalex.org/C167928553","wikidata":"https://www.wikidata.org/wiki/Q1376021","display_name":"Estimation theory","level":2,"score":0.41334718465805054},{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.3970036208629608},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.38983413577079773},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.349836140871048},{"id":"https://openalex.org/C28826006","wikidata":"https://www.wikidata.org/wiki/Q33521","display_name":"Applied mathematics","level":1,"score":0.31992197036743164},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.26451215147972107},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.23560887575149536},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.19122380018234253},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.14711475372314453},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.11361613869667053},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.23919/ecc.2013.6669467","is_oa":false,"landing_page_url":"https://doi.org/10.23919/ecc.2013.6669467","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 European Control Conference (ECC)","raw_type":"proceedings-article"},{"id":"pmh:oai:HAL:hal-00818902v1","is_oa":false,"landing_page_url":"https://inria.hal.science/hal-00818902","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6669467&isnumber=6669080","raw_type":"Conference papers"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1483307070","https://openalex.org/W1499965417","https://openalex.org/W1973239973","https://openalex.org/W1988791304","https://openalex.org/W1994794118","https://openalex.org/W1998586062","https://openalex.org/W2018435536","https://openalex.org/W2046451925","https://openalex.org/W2051501315","https://openalex.org/W2057107775","https://openalex.org/W2097610177","https://openalex.org/W2099579103","https://openalex.org/W2106411386","https://openalex.org/W2122121413","https://openalex.org/W2123487311","https://openalex.org/W2124202837","https://openalex.org/W2127740987","https://openalex.org/W2138163236","https://openalex.org/W2157886837","https://openalex.org/W2164343005","https://openalex.org/W2915445490","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2015530857","https://openalex.org/W2556064263","https://openalex.org/W1991846142","https://openalex.org/W1583020711","https://openalex.org/W4252024964","https://openalex.org/W4253883008","https://openalex.org/W2370409284","https://openalex.org/W171914860","https://openalex.org/W2060317829","https://openalex.org/W4249297485"],"abstract_inverted_index":{"We":[0,14,36],"address":[1],"state":[2,133],"estimation":[3,134],"for":[4,60],"gene":[5],"regulatory":[6],"networks":[7],"at":[8],"the":[9,38,53,61,87,118,122],"level":[10],"of":[11,24,32,55,63,86,109,124],"single":[12],"cells.":[13],"consider":[15,71],"models":[16],"that":[17,103,108,121],"include":[18],"both":[19],"intrinsic":[20],"noise,":[21,29],"in":[22,30,93],"terms":[23,31],"stochastic":[25,56],"dynamics,":[26],"and":[27,51,120],"extrinsic":[28],"random":[33,44],"parameter":[34,127],"values.":[35],"take":[37],"Chemical":[39,81],"Master":[40],"Equation":[41,83],"(CME)":[42],"with":[43],"parameters":[45],"as":[46,97],"a":[47,72,80,98,110],"reference":[48],"modeling":[49],"approach,":[50],"investigate":[52],"use":[54,123],"differential":[57],"model":[58],"approximations":[59],"construction":[62],"practical":[64],"real-time":[65],"filters.":[66],"To":[67],"this":[68],"aim":[69],"we":[70,101],"Square-Root":[73],"Unscented":[74],"Kalman":[75],"Filter":[76],"(SRUKF)":[77],"built":[78,115],"on":[79,117],"Langevin":[82],"(CLE)":[84],"approximation":[85],"CME.":[88],"Using":[89],"arabinose":[90],"uptake":[91],"regulation":[92],"Escherichia":[94],"coli":[95],"bacteria":[96],"case":[99],"study,":[100],"show":[102],"performance":[104],"is":[105],"comparable":[106],"to":[107,131],"(computationally":[111],"heavier)":[112],"particle":[113],"filter":[114],"directly":[116],"CME,":[119],"information":[125],"about":[126],"uncertainty":[128],"allows":[129],"one":[130],"improve":[132],"performance.":[135]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}