{"id":"https://openalex.org/W4206476188","doi":"https://doi.org/10.23919/cinc53138.2021.9662939","title":"Changes in RR Series Characteristics During Atrial Fibrillation: An AV Node Simulation Study","display_name":"Changes in RR Series Characteristics During Atrial Fibrillation: An AV Node Simulation Study","publication_year":2021,"publication_date":"2021-09-13","ids":{"openalex":"https://openalex.org/W4206476188","doi":"https://doi.org/10.23919/cinc53138.2021.9662939"},"language":"en","primary_location":{"id":"doi:10.23919/cinc53138.2021.9662939","is_oa":false,"landing_page_url":"https://doi.org/10.23919/cinc53138.2021.9662939","pdf_url":null,"source":{"id":"https://openalex.org/S4363605378","display_name":"2021 Computing in Cardiology (CinC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 Computing in Cardiology (CinC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054936780","display_name":"Felix Plappert","orcid":"https://orcid.org/0000-0002-1028-4276"},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Felix Plappert","raw_affiliation_strings":["Department of Biomedical Engineering, Lund University, Lund, Sweden"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075530576","display_name":"Mikael Wallman","orcid":"https://orcid.org/0000-0002-2519-736X"},"institutions":[{"id":"https://openalex.org/I4210139723","display_name":"Fraunhofer Chalmers Research Centre for Industrial Mathematics","ror":"https://ror.org/03tqh5n18","country_code":"SE","type":"nonprofit","lineage":["https://openalex.org/I4210139723","https://openalex.org/I4923324"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Mikael Wallman","raw_affiliation_strings":["Department of Systems and Data Analysis, Fraunhofer-Chalmers Centre, Sweden"],"affiliations":[{"raw_affiliation_string":"Department of Systems and Data Analysis, Fraunhofer-Chalmers Centre, Sweden","institution_ids":["https://openalex.org/I4210139723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044689027","display_name":"Pyotr G. Platonov","orcid":"https://orcid.org/0000-0002-5592-8717"},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Pyotr Platonov","raw_affiliation_strings":["Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden"],"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072258666","display_name":"Frida Sandberg","orcid":"https://orcid.org/0000-0002-1956-6333"},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Frida Sandberg","raw_affiliation_strings":["Department of Biomedical Engineering, Lund University, Lund, Sweden"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5054936780"],"corresponding_institution_ids":["https://openalex.org/I187531555"],"apc_list":null,"apc_paid":null,"fwci":0.3451,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.49557522,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11021","display_name":"ECG Monitoring and Analysis","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sample-entropy","display_name":"Sample entropy","score":0.6855556964874268},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"Atrial fibrillation","score":0.63861083984375},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.5367305278778076},{"id":"https://openalex.org/keywords/linear-regression","display_name":"Linear regression","score":0.524206280708313},{"id":"https://openalex.org/keywords/standard-deviation","display_name":"Standard deviation","score":0.5240473747253418},{"id":"https://openalex.org/keywords/atrioventricular-node","display_name":"Atrioventricular node","score":0.48494890332221985},{"id":"https://openalex.org/keywords/refractory-period","display_name":"Refractory period","score":0.4699918031692505},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.4674103558063507},{"id":"https://openalex.org/keywords/electrocardiography","display_name":"Electrocardiography","score":0.4394308924674988},{"id":"https://openalex.org/keywords/impulse","display_name":"Impulse (physics)","score":0.43813008069992065},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4042118191719055},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.29757797718048096},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.24472364783287048},{"id":"https://openalex.org/keywords/time-series","display_name":"Time series","score":0.18492141366004944},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.10217297077178955},{"id":"https://openalex.org/keywords/tachycardia","display_name":"Tachycardia","score":0.1013597846031189}],"concepts":[{"id":"https://openalex.org/C66696666","wikidata":"https://www.wikidata.org/wiki/Q17105612","display_name":"Sample entropy","level":3,"score":0.6855556964874268},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.63861083984375},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5367305278778076},{"id":"https://openalex.org/C48921125","wikidata":"https://www.wikidata.org/wiki/Q10861030","display_name":"Linear regression","level":2,"score":0.524206280708313},{"id":"https://openalex.org/C22679943","wikidata":"https://www.wikidata.org/wiki/Q159375","display_name":"Standard deviation","level":2,"score":0.5240473747253418},{"id":"https://openalex.org/C2776024998","wikidata":"https://www.wikidata.org/wiki/Q509053","display_name":"Atrioventricular node","level":3,"score":0.48494890332221985},{"id":"https://openalex.org/C70616116","wikidata":"https://www.wikidata.org/wiki/Q1736732","display_name":"Refractory period","level":2,"score":0.4699918031692505},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4674103558063507},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.4394308924674988},{"id":"https://openalex.org/C70836080","wikidata":"https://www.wikidata.org/wiki/Q837940","display_name":"Impulse (physics)","level":2,"score":0.43813008069992065},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4042118191719055},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.29757797718048096},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.24472364783287048},{"id":"https://openalex.org/C151406439","wikidata":"https://www.wikidata.org/wiki/Q186588","display_name":"Time series","level":2,"score":0.18492141366004944},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10217297077178955},{"id":"https://openalex.org/C2780283014","wikidata":"https://www.wikidata.org/wiki/Q209583","display_name":"Tachycardia","level":2,"score":0.1013597846031189},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.23919/cinc53138.2021.9662939","is_oa":false,"landing_page_url":"https://doi.org/10.23919/cinc53138.2021.9662939","pdf_url":null,"source":{"id":"https://openalex.org/S4363605378","display_name":"2021 Computing in Cardiology (CinC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 Computing in Cardiology (CinC)","raw_type":"proceedings-article"},{"id":"pmh:oai:lup.lub.lu.se:4c36a2a3-4817-4e0c-9be4-e7df8d7fe8a6","is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/4c36a2a3-4817-4e0c-9be4-e7df8d7fe8a6","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 2325-8861","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8399999737739563,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1862394037","https://openalex.org/W2026889608","https://openalex.org/W2062654881","https://openalex.org/W2100710400","https://openalex.org/W2126798028","https://openalex.org/W2342420743","https://openalex.org/W2580499703","https://openalex.org/W2734337887","https://openalex.org/W2772601205","https://openalex.org/W2896576092","https://openalex.org/W2947158333","https://openalex.org/W3082188176","https://openalex.org/W6782723006"],"related_works":["https://openalex.org/W2125586748","https://openalex.org/W2097536423","https://openalex.org/W2097173052","https://openalex.org/W2164710760","https://openalex.org/W2002205477","https://openalex.org/W2019030800","https://openalex.org/W1989961089","https://openalex.org/W2130761297","https://openalex.org/W2025921108","https://openalex.org/W2358977804"],"abstract_inverted_index":{"The":[0,47,60],"atrioventricular":[1],"node":[2],"(AVN)":[3],"plays":[4],"an":[5,113,123],"important":[6],"role":[7],"in":[8,23,36,115,125,135,145,150,165,172,180,185,193],"rate":[9,44,188],"control":[10,45,189],"during":[11,41],"atrial":[12,61,158,195],"fibrillation":[13],"(AF).":[14],"To":[15],"further":[16],"our":[17],"understanding":[18],"of":[19,50,58,92,129,156],"the":[20,51,86,93,116,126,130,151,157,194,203],"AVN":[21,31,52],"function":[22],"AF,":[24],"we":[25],"present":[26],"a":[27,56,67],"model-based":[28],"study,":[29],"relating":[30],"electrophysiological":[32],"characteristics":[33,39],"to":[34,187,206],"changes":[35,134,144,149,164,171,179,192],"RR":[37,95,117,136,139,166,173,181],"series":[38,63,96,182],"observed":[40,83,184],"treatment":[42],"with":[43,66,75,122,143,163,170,209],"drugs.":[46],"dual-pathway":[48],"physiology":[49],"was":[53,64,119],"modelled":[54,65],"using":[55,108],"network":[57],"nodes.":[59],"impulse":[62,159],"Pearson":[68],"Type":[69],"IV":[70],"distribution.":[71],"Simulations":[72],"were":[73,97,141,161],"performed":[74],"randomly":[76],"generated":[77],"model":[78],"parameters":[79],"based":[80],"on":[81],"clinically":[82],"ranges":[84],"and":[85,90,103,138,153,198],"heart":[87],"rate,":[88],"variability":[89,137],"irregularity":[91,140,167],"resulting":[94],"quantified":[98],"by":[99],"their":[100],"mean,":[101],"rmssd":[102],"sample":[104],"entropy,":[105],"respectively.":[106],"Analysis":[107],"linear":[109],"regression":[110],"showed":[111],"that":[112,178],"increase":[114,124],"mean":[118,152],"predominantly":[120],"associated":[121,142,162],"refractory":[127],"period":[128],"slow":[131],"pathway,":[132],"whereas":[133],"conduction":[146,200],"delay.":[147],"Notably,":[148],"standard":[154],"deviation":[155],"intervals":[160],"but":[168],"not":[169],"variability.":[174],"Our":[175],"results":[176,204],"suggest":[177],"dynamics":[183],"response":[186],"drugs":[190],"reflect":[191],"electrical":[196],"activity":[197],"AV":[199],"delay,":[201],"however":[202],"needs":[205],"be":[207],"verified":[208],"clinical":[210],"data.":[211]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}