{"id":"https://openalex.org/W2885137364","doi":"https://doi.org/10.23919/acc.2018.8431668","title":"The Impact of a Responsive Endogenous Pancreas in Critical Care Glucose Control","display_name":"The Impact of a Responsive Endogenous Pancreas in Critical Care Glucose Control","publication_year":2018,"publication_date":"2018-06-01","ids":{"openalex":"https://openalex.org/W2885137364","doi":"https://doi.org/10.23919/acc.2018.8431668","mag":"2885137364"},"language":"en","primary_location":{"id":"doi:10.23919/acc.2018.8431668","is_oa":false,"landing_page_url":"https://doi.org/10.23919/acc.2018.8431668","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 Annual American Control Conference (ACC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003531394","display_name":"Robert S. Parker","orcid":"https://orcid.org/0000-0002-9913-4847"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert S. Parker","raw_affiliation_strings":["Department of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002202160","display_name":"Timothy D. Knab","orcid":null},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy D. Knab","raw_affiliation_strings":["Department of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082272833","display_name":"Gilles Clermont","orcid":"https://orcid.org/0000-0002-0163-1379"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. Clermont","raw_affiliation_strings":["Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":null,"apc_paid":null,"fwci":0.838,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.76782077,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"3595","last_page":"3601"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.9850999712944031,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intensive-care-unit","display_name":"Intensive care unit","score":0.6471331715583801},{"id":"https://openalex.org/keywords/artificial-pancreas","display_name":"Artificial pancreas","score":0.6441164612770081},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.6270769834518433},{"id":"https://openalex.org/keywords/pancreas","display_name":"Pancreas","score":0.5989017486572266},{"id":"https://openalex.org/keywords/pid-controller","display_name":"PID controller","score":0.5580036044120789},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5466727018356323},{"id":"https://openalex.org/keywords/intensive-care-medicine","display_name":"Intensive care medicine","score":0.538374125957489},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"Diabetes mellitus","score":0.511993944644928},{"id":"https://openalex.org/keywords/endogeny","display_name":"Endogeny","score":0.47083616256713867},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.38354435563087463},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.2788352072238922},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.2113170027732849},{"id":"https://openalex.org/keywords/control-engineering","display_name":"Control engineering","score":0.19655799865722656},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1330181062221527},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.12868747115135193},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"Type 1 diabetes","score":0.0931849479675293}],"concepts":[{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.6471331715583801},{"id":"https://openalex.org/C2780353609","wikidata":"https://www.wikidata.org/wiki/Q1569064","display_name":"Artificial pancreas","level":4,"score":0.6441164612770081},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6270769834518433},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.5989017486572266},{"id":"https://openalex.org/C47116090","wikidata":"https://www.wikidata.org/wiki/Q716829","display_name":"PID controller","level":3,"score":0.5580036044120789},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5466727018356323},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.538374125957489},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.511993944644928},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.47083616256713867},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38354435563087463},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2788352072238922},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2113170027732849},{"id":"https://openalex.org/C133731056","wikidata":"https://www.wikidata.org/wiki/Q4917288","display_name":"Control engineering","level":1,"score":0.19655799865722656},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1330181062221527},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.12868747115135193},{"id":"https://openalex.org/C2781232474","wikidata":"https://www.wikidata.org/wiki/Q124407","display_name":"Type 1 diabetes","level":3,"score":0.0931849479675293},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C536315585","wikidata":"https://www.wikidata.org/wiki/Q7698332","display_name":"Temperature control","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.23919/acc.2018.8431668","is_oa":false,"landing_page_url":"https://doi.org/10.23919/acc.2018.8431668","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 Annual American Control Conference (ACC)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1600232156","https://openalex.org/W1606245564","https://openalex.org/W1800997121","https://openalex.org/W1980717583","https://openalex.org/W1991725952","https://openalex.org/W2043841962","https://openalex.org/W2059279902","https://openalex.org/W2075805067","https://openalex.org/W2079028200","https://openalex.org/W2079569240","https://openalex.org/W2112298695","https://openalex.org/W2112668884","https://openalex.org/W2127277443","https://openalex.org/W2134293572","https://openalex.org/W2135854640","https://openalex.org/W2148568711","https://openalex.org/W2153777416","https://openalex.org/W2155352315","https://openalex.org/W2162557622","https://openalex.org/W2570825188","https://openalex.org/W6636121220"],"related_works":["https://openalex.org/W2002388147","https://openalex.org/W3098928304","https://openalex.org/W2394883510","https://openalex.org/W4392771688","https://openalex.org/W3045686306","https://openalex.org/W2150958483","https://openalex.org/W2165013373","https://openalex.org/W2922503265","https://openalex.org/W2023324176","https://openalex.org/W2121097709"],"abstract_inverted_index":{"Critical":[0],"care":[1,42,86,156,175],"patients":[2,89,141],"suffer":[3],"from":[4,9,79,84,143],"stress":[5],"hyperglycemia,":[6],"but":[7],"differ":[8],"ambulatory":[10],"diabetics":[11,25],"by":[12],"the":[13,35,52,59,70,81,110,128,147,169],"presence":[14],"of":[15,73,104,109,112,123,130,173],"a":[16,32,65],"working,":[17,53],"albeit":[18],"malfunctioning,":[19,98],"endogenous":[20,125],"pancreas.":[21],"Control":[22],"systems":[23],"for":[24,31],"can":[26],"be":[27,47,93],"designed":[28],"without":[29],"concern":[30],"pancreas,":[33],"as":[34,135],"pancreas":[36,57],"is":[37],"no":[38],"longer":[39],"responsive;":[40],"critical":[41,155,174],"glucose":[43,113],"control":[44,114],"algorithms":[45],"must":[46],"able":[48],"to":[49,51,68,92,137,149,160,167,171],"respond":[50],"and":[54,96,159],"presumably":[55],"healing,":[56],"in":[58,117,127,138,154],"recovering":[60],"patient.":[61],"We":[62],"construct":[63],"herein":[64],"PID-derived":[66],"algorithm":[67],"capture":[69],"pancreatic":[71],"response":[72],"ICU":[74,119,162],"patients.":[75,120,176],"Using":[76],"clinical":[77,144],"data":[78],"UPMC,":[80],"PID":[82],"parameters":[83],"intensive":[85],"unit":[87],"(ICU)":[88],"are":[90],"shown":[91],"both":[94],"variable,":[95],"potentially":[97],"e.g.,":[99],"possessing":[100],"an":[101],"integral":[102],"gain":[103],"0":[105],"-":[106],"clearly":[107],"demonstrative":[108],"loss":[111],"commonly":[115,131],"observed":[116],"post-surgical":[118],"The":[121],"impacts":[122],"this":[124,151],"responsivity,":[126],"context":[129],"employed":[132],"diabetic":[133],"challenges":[134],"administered":[136],"silico":[139],"virtual":[140],"developed":[142],"data,":[145],"demonstrate":[146],"need":[148],"incorporate":[150],"responsive":[152],"system":[153],"controller":[157],"design,":[158],"design":[161],"controllers":[163],"with":[164],"adaptive":[165],"elements":[166],"manage":[168],"return":[170],"health":[172]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}