{"id":"https://openalex.org/W2284747174","doi":"https://doi.org/10.2312/egp.20151038","title":"A Computational Model of Light-Sheet Fluorescence Microscopy using Physically-based Rendering","display_name":"A Computational Model of Light-Sheet Fluorescence Microscopy using Physically-based Rendering","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2284747174","doi":"https://doi.org/10.2312/egp.20151038","mag":"2284747174"},"language":"en","primary_location":{"id":"doi:10.2312/egp.20151038","is_oa":true,"landing_page_url":"https://doi.org/10.2312/egp.20151038","pdf_url":null,"source":{"id":"https://openalex.org/S7407052899","display_name":"Eurographics","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},"type":"article","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.2312/egp.20151038","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011611586","display_name":"Marwan Abdellah","orcid":"https://orcid.org/0000-0003-0751-2300"},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Abdellah, Marwan","raw_affiliation_strings":["\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102843750","display_name":"Ahmet Bilgili","orcid":"https://orcid.org/0000-0002-5449-2114"},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Bilgili, Ahmet","raw_affiliation_strings":["\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068088058","display_name":"Stefan Eilemann","orcid":"https://orcid.org/0000-0002-1510-1109"},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Eilemann, Stefan","raw_affiliation_strings":["\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069964239","display_name":"Henry Markram","orcid":"https://orcid.org/0000-0001-6164-2590"},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Markram, Henry","raw_affiliation_strings":["\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088028124","display_name":"Felix Sch\u00fcrmann","orcid":null},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Sch\u00fcrmann, Felix","raw_affiliation_strings":["\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.8661999702453613,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.8661999702453613,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10481","display_name":"Computer Graphics and Visualization Techniques","score":0.8377000093460083,"subfield":{"id":"https://openalex.org/subfields/1704","display_name":"Computer Graphics and Computer-Aided Design"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/light-sheet-fluorescence-microscopy","display_name":"Light sheet fluorescence microscopy","score":0.8473004102706909},{"id":"https://openalex.org/keywords/rendering","display_name":"Rendering (computer graphics)","score":0.660571277141571},{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.6351762413978577},{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.5686710476875305},{"id":"https://openalex.org/keywords/fluorescence-microscope","display_name":"Fluorescence microscope","score":0.5600087642669678},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43200957775115967},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.386797159910202},{"id":"https://openalex.org/keywords/computer-graphics","display_name":"Computer graphics (images)","score":0.38662707805633545},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.3317209482192993},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.16874819993972778}],"concepts":[{"id":"https://openalex.org/C113976765","wikidata":"https://www.wikidata.org/wiki/Q1823502","display_name":"Light sheet fluorescence microscopy","level":4,"score":0.8473004102706909},{"id":"https://openalex.org/C205711294","wikidata":"https://www.wikidata.org/wiki/Q176953","display_name":"Rendering (computer graphics)","level":2,"score":0.660571277141571},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.6351762413978577},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.5686710476875305},{"id":"https://openalex.org/C169274487","wikidata":"https://www.wikidata.org/wiki/Q840211","display_name":"Fluorescence microscope","level":3,"score":0.5600087642669678},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43200957775115967},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.386797159910202},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.38662707805633545},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3317209482192993},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16874819993972778}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2312/egp.20151038","is_oa":true,"landing_page_url":"https://doi.org/10.2312/egp.20151038","pdf_url":null,"source":{"id":"https://openalex.org/S7407052899","display_name":"Eurographics","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.2312/egp.20151038","is_oa":true,"landing_page_url":"https://doi.org/10.2312/egp.20151038","pdf_url":null,"source":{"id":"https://openalex.org/S7407052899","display_name":"Eurographics","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},"sustainable_development_goals":[{"score":0.4099999964237213,"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2116042222","https://openalex.org/W2773956148","https://openalex.org/W2883399272","https://openalex.org/W2871729377","https://openalex.org/W2332744733","https://openalex.org/W2766337404","https://openalex.org/W2121331303","https://openalex.org/W2915400459","https://openalex.org/W1949884476","https://openalex.org/W2153437487","https://openalex.org/W3137325931","https://openalex.org/W2231575859","https://openalex.org/W2117511222","https://openalex.org/W2725774279","https://openalex.org/W3007071022","https://openalex.org/W1617087788","https://openalex.org/W2071954097","https://openalex.org/W2052661379","https://openalex.org/W2891955732","https://openalex.org/W2827545588"],"abstract_inverted_index":{"We":[0,79],"present":[1],"a":[2,88,99],"physically-based":[3],"computational":[4],"model":[5,92],"of":[6,32,49,76,83,98],"the":[7,25,33,46,69,95],"light":[8,57],"sheet":[9],"fluorescence":[10,39,70],"microscope":[11],"(LSFM).":[12],"Based":[13],"on":[14],"Monte":[15],"Carlo":[16],"ray":[17],"tracing":[18],"and":[19,28,73],"geometric":[20],"optics,":[21],"our":[22,84],"method":[23],"simulates":[24],"operational":[26],"aspects":[27],"image":[29],"formation":[30],"process":[31],"LSFM.":[34],"An":[35],"extension":[36,64],"for":[37,45],"previous":[38],"models":[40],"is":[41],"developed":[42],"to":[43,54,87],"account":[44],"intrinsic":[47],"characteristics":[48],"fluorescent":[50],"dyes":[51],"in":[52],"order":[53],"accurately":[55],"simulate":[56],"interaction":[58],"with":[59],"fluorescent-tagged":[60],"biological":[61],"specimen.":[62],"This":[63],"was":[65],"quantitatively":[66],"validated":[67],"against":[68],"brightness":[71],"equation":[72],"experimental":[74],"spectra":[75],"different":[77],"dyes.":[78],"demonstrate":[80],"first":[81],"results":[82],"rendering":[85],"pipeline":[86],"simplified":[89],"brain":[90],"tissue":[91],"reconstructed":[93],"from":[94],"somatosensory":[96],"cortex":[97],"young":[100],"rat.":[101]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}