{"id":"https://openalex.org/W2794873808","doi":"https://doi.org/10.22489/cinc.2017.332-298","title":"Effect of Chronic Hypoxia on Autonomic Nervous System of Fetal Mice","display_name":"Effect of Chronic Hypoxia on Autonomic Nervous System of Fetal Mice","publication_year":2017,"publication_date":"2017-09-14","ids":{"openalex":"https://openalex.org/W2794873808","doi":"https://doi.org/10.22489/cinc.2017.332-298","mag":"2794873808"},"language":"en","primary_location":{"id":"doi:10.22489/cinc.2017.332-298","is_oa":true,"landing_page_url":"http://doi.org/10.22489/cinc.2017.332-298","pdf_url":"https://doi.org/10.22489/cinc.2017.332-298","source":{"id":"https://openalex.org/S4220650825","display_name":"Computing in cardiology","issn_l":"2325-8861","issn":["2325-8861","2325-887X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320439","host_organization_name":"IEEE Computer Society","host_organization_lineage":["https://openalex.org/P4310320439","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Computer Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computing in Cardiology Conference (CinC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.22489/cinc.2017.332-298","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053525471","display_name":"Ahsan H. Khandoker","orcid":"https://orcid.org/0000-0002-0636-1646"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I176601375","display_name":"Khalifa University of Science and Technology","ror":"https://ror.org/05hffr360","country_code":"AE","type":"education","lineage":["https://openalex.org/I176601375"]}],"countries":["AE","AU"],"is_corresponding":true,"raw_author_name":"Ahsan Khandoker","raw_affiliation_strings":["Khalifa University, Abu Dhabi, UAE","The University of Melbourne, Parkville, Australia"],"affiliations":[{"raw_affiliation_string":"Khalifa University, Abu Dhabi, UAE","institution_ids":["https://openalex.org/I176601375"]},{"raw_affiliation_string":"The University of Melbourne, Parkville, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025112995","display_name":"Thuraia Al Khoori","orcid":null},"institutions":[{"id":"https://openalex.org/I176601375","display_name":"Khalifa University of Science and Technology","ror":"https://ror.org/05hffr360","country_code":"AE","type":"education","lineage":["https://openalex.org/I176601375"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Thuraia Al Khoori","raw_affiliation_strings":["Khalifa University, Abu Dhabi, UAE"],"affiliations":[{"raw_affiliation_string":"Khalifa University, Abu Dhabi, UAE","institution_ids":["https://openalex.org/I176601375"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078727618","display_name":"Takahiro Minato","orcid":"https://orcid.org/0000-0003-4381-3741"},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takahiro Minato","raw_affiliation_strings":["Tohoku University, Sendai, Japan"],"affiliations":[{"raw_affiliation_string":"Tohoku University, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110088249","display_name":"Takuya Ito","orcid":null},"institutions":[{"id":"https://openalex.org/I146500386","display_name":"Jichi Medical University","ror":"https://ror.org/010hz0g26","country_code":"JP","type":"education","lineage":["https://openalex.org/I146500386"]},{"id":"https://openalex.org/I4210153031","display_name":"Jichi Medical University Hospital","ror":"https://ror.org/04at0zw32","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210153031"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takuya Ito","raw_affiliation_strings":["Jichi Medical University, Japan"],"affiliations":[{"raw_affiliation_string":"Jichi Medical University, Japan","institution_ids":["https://openalex.org/I146500386","https://openalex.org/I4210153031"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101900764","display_name":"Yoshitaka Kimura","orcid":"https://orcid.org/0000-0002-1719-9357"},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshitaka Kimura","raw_affiliation_strings":["Tohoku University, Sendai, Japan"],"affiliations":[{"raw_affiliation_string":"Tohoku University, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5053525471"],"corresponding_institution_ids":["https://openalex.org/I165779595","https://openalex.org/I176601375"],"apc_list":null,"apc_paid":null,"fwci":0.2321,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.50156567,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9908999800682068,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autonomic-nervous-system","display_name":"Autonomic nervous system","score":0.7250303626060486},{"id":"https://openalex.org/keywords/hypoxia","display_name":"Hypoxia (environmental)","score":0.7075898051261902},{"id":"https://openalex.org/keywords/fetus","display_name":"Fetus","score":0.5495967268943787},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4657370150089264},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.35964435338974},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.32099175453186035},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2494150996208191},{"id":"https://openalex.org/keywords/pregnancy","display_name":"Pregnancy","score":0.16422370076179504},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.13032731413841248},{"id":"https://openalex.org/keywords/oxygen","display_name":"Oxygen","score":0.1153496503829956},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.08175024390220642},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.06865385174751282}],"concepts":[{"id":"https://openalex.org/C2777372248","wikidata":"https://www.wikidata.org/wiki/Q171064","display_name":"Autonomic nervous system","level":4,"score":0.7250303626060486},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.7075898051261902},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.5495967268943787},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4657370150089264},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35964435338974},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.32099175453186035},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2494150996208191},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.16422370076179504},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.13032731413841248},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.1153496503829956},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.08175024390220642},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.06865385174751282},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.22489/cinc.2017.332-298","is_oa":true,"landing_page_url":"http://doi.org/10.22489/cinc.2017.332-298","pdf_url":"https://doi.org/10.22489/cinc.2017.332-298","source":{"id":"https://openalex.org/S4220650825","display_name":"Computing in cardiology","issn_l":"2325-8861","issn":["2325-8861","2325-887X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320439","host_organization_name":"IEEE Computer Society","host_organization_lineage":["https://openalex.org/P4310320439","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Computer Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computing in Cardiology Conference (CinC)","raw_type":"proceedings-article"}],"best_oa_location":{"id":"doi:10.22489/cinc.2017.332-298","is_oa":true,"landing_page_url":"http://doi.org/10.22489/cinc.2017.332-298","pdf_url":"https://doi.org/10.22489/cinc.2017.332-298","source":{"id":"https://openalex.org/S4220650825","display_name":"Computing in cardiology","issn_l":"2325-8861","issn":["2325-8861","2325-887X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320439","host_organization_name":"IEEE Computer Society","host_organization_lineage":["https://openalex.org/P4310320439","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Computer Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computing in Cardiology Conference (CinC)","raw_type":"proceedings-article"},"sustainable_development_goals":[{"score":0.6100000143051147,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322334","display_name":"Khalifa University of Science, Technology and Research","ror":"https://ror.org/05hffr360"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2794873808.pdf","grobid_xml":"https://content.openalex.org/works/W2794873808.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W1551890621","https://openalex.org/W1974202399","https://openalex.org/W1989022363","https://openalex.org/W2032024298","https://openalex.org/W2036521161","https://openalex.org/W2078510393","https://openalex.org/W2111988227","https://openalex.org/W2123183805","https://openalex.org/W2128466264","https://openalex.org/W2133589238","https://openalex.org/W2535967169"],"related_works":["https://openalex.org/W1966504330","https://openalex.org/W1979139803","https://openalex.org/W2037631372","https://openalex.org/W2073527559","https://openalex.org/W2030889776","https://openalex.org/W2159000141","https://openalex.org/W2070567609","https://openalex.org/W1974041167","https://openalex.org/W2391409986","https://openalex.org/W1978297557"],"abstract_inverted_index":{"The":[0],"aim":[1],"of":[2,33,140,156],"this":[3],"study":[4],"is":[5,143],"to":[6,74,145],"investigate":[7],"how":[8],"chronic":[9,47,51,77,130,141,178],"hypoxia":[10,48,52,131,142,179],"could":[11],"affect":[12],"the":[13,61,126,153,170],"autonomic":[14],"nervous":[15,175],"system":[16,176],"in":[17,72,84,122,129,152,161,172,184],"fetal":[18,166,185],"mouse":[19],"(at":[20],"gestational":[21],"day":[22,55],"17.5)":[23],"by":[24,101],"using":[25,102],"an":[26,103],"invasive":[27,104],"Fetal":[28],"Electrocardiography":[29],"(FECG)":[30],"technique.":[31],"Total":[32],"33":[34],"pregnant":[35],"female":[36],"mice":[37,53,80,167],"were":[38,58,65,81,96],"divided":[39],"into":[40],"two":[41,108],"groups":[42],"(sham":[43],"control":[44],"(N=13)":[45],"and":[46,111],"(N=20)).":[49],"In":[50],"at":[54],"15.5,":[56],"ligations":[57],"placed":[59],"around":[60],"uterine":[62],"vessels":[63],"that":[64,116],"tied":[66],"with":[67],"nylon":[68],"thread":[69],"0.5":[70],"mm":[71],"diameter":[73],"induce":[75],"partially":[76],"hypoxia.":[78],"Sham":[79],"operated":[82],"on":[83,149,164],"a":[85,112],"fashion":[86],"similarly":[87],"but":[88],"without":[89],"ligation.":[90],"On":[91,125],"17.5-day":[92],"beat-to-beat":[93],"heart":[94],"intervals":[95],"measured":[97],"for":[98],"20":[99],"minutes":[100],"FECG":[105],"techniques":[106],"inserting":[107],"needle":[109],"electrodes":[110],"ground.":[113],"Results":[114],"show":[115],"tone":[117,133,150],"decreases":[118],"when":[119,135],"entropy":[120,136,157],"increases":[121,134],"sham":[123],"group.":[124],"other":[127],"hand":[128],"group":[132],"increases.":[137],"Therefore,":[138],"effect":[139,163],"shown":[144],"have":[146],"more":[147,181],"pronounced":[148],"values":[151,158],"higher":[154],"range":[155],"(4.2~6.0).":[159],"Differences":[160],"hypoxic":[162],"individual":[165],"might":[168],"represent":[169],"differences":[171],"maturating":[173],"sympathetic":[174,182],"because":[177],"induces":[180],"influences":[183],"mice.":[186]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}