{"id":"https://openalex.org/W2794904257","doi":"https://doi.org/10.22489/cinc.2017.312-025","title":"One-dimensional Simulation of Alternating Conduction under Hyperkalaemic Conditions","display_name":"One-dimensional Simulation of Alternating Conduction under Hyperkalaemic Conditions","publication_year":2017,"publication_date":"2017-09-14","ids":{"openalex":"https://openalex.org/W2794904257","doi":"https://doi.org/10.22489/cinc.2017.312-025","mag":"2794904257"},"language":"en","primary_location":{"id":"doi:10.22489/cinc.2017.312-025","is_oa":true,"landing_page_url":"http://doi.org/10.22489/cinc.2017.312-025","pdf_url":"https://doi.org/10.22489/cinc.2017.312-025","source":{"id":"https://openalex.org/S4220650825","display_name":"Computing in cardiology","issn_l":"2325-8861","issn":["2325-8861","2325-887X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320439","host_organization_name":"IEEE Computer Society","host_organization_lineage":["https://openalex.org/P4310320439","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Computer Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computing in Cardiology Conference (CinC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.22489/cinc.2017.312-025","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100390383","display_name":"Jiaqi Liu","orcid":"https://orcid.org/0009-0004-9262-3754"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jiaqi Liu","raw_affiliation_strings":["Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101636346","display_name":"Yuan Gao","orcid":"https://orcid.org/0000-0002-8305-5466"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan Gao","raw_affiliation_strings":["Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029627686","display_name":"Yinglan Gong","orcid":"https://orcid.org/0000-0003-1533-1446"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yinglan Gong","raw_affiliation_strings":["Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073559766","display_name":"Ling Xia","orcid":"https://orcid.org/0000-0002-1937-9693"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ling Xia","raw_affiliation_strings":["Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103077480","display_name":"Wenlong Xu","orcid":"https://orcid.org/0000-0002-7485-8638"},"institutions":[{"id":"https://openalex.org/I55538621","display_name":"China Jiliang University","ror":"https://ror.org/05v1y0t93","country_code":"CN","type":"education","lineage":["https://openalex.org/I55538621"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenlong Xu","raw_affiliation_strings":["China Jiliang University, Hangzhou 310018, China"],"affiliations":[{"raw_affiliation_string":"China Jiliang University, Hangzhou 310018, China","institution_ids":["https://openalex.org/I55538621"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002822938","display_name":"Mingfeng Jiang","orcid":"https://orcid.org/0000-0003-3013-4790"},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingfeng Jiang","raw_affiliation_strings":["Zhejiang Sci-Tech University, Hangzhou 310018, China"],"affiliations":[{"raw_affiliation_string":"Zhejiang Sci-Tech University, Hangzhou 310018, China","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035068745","display_name":"Gangmin Ning","orcid":"https://orcid.org/0000-0001-9107-5785"},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gangmin Ning","raw_affiliation_strings":["Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5100390383"],"corresponding_institution_ids":["https://openalex.org/I76130692"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.32083221,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12495","display_name":"Electrostatic Discharge in Electronics","score":0.9745000004768372,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thermal-conduction","display_name":"Thermal conduction","score":0.6025867462158203},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.473811537027359},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.3513230085372925},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2155064344406128},{"id":"https://openalex.org/keywords/thermodynamics","display_name":"Thermodynamics","score":0.2119472324848175}],"concepts":[{"id":"https://openalex.org/C172100665","wikidata":"https://www.wikidata.org/wiki/Q7465774","display_name":"Thermal conduction","level":2,"score":0.6025867462158203},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.473811537027359},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3513230085372925},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2155064344406128},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.2119472324848175}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.22489/cinc.2017.312-025","is_oa":true,"landing_page_url":"http://doi.org/10.22489/cinc.2017.312-025","pdf_url":"https://doi.org/10.22489/cinc.2017.312-025","source":{"id":"https://openalex.org/S4220650825","display_name":"Computing in cardiology","issn_l":"2325-8861","issn":["2325-8861","2325-887X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320439","host_organization_name":"IEEE Computer Society","host_organization_lineage":["https://openalex.org/P4310320439","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Computer Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computing in Cardiology Conference (CinC)","raw_type":"proceedings-article"}],"best_oa_location":{"id":"doi:10.22489/cinc.2017.312-025","is_oa":true,"landing_page_url":"http://doi.org/10.22489/cinc.2017.312-025","pdf_url":"https://doi.org/10.22489/cinc.2017.312-025","source":{"id":"https://openalex.org/S4220650825","display_name":"Computing in cardiology","issn_l":"2325-8861","issn":["2325-8861","2325-887X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320439","host_organization_name":"IEEE Computer Society","host_organization_lineage":["https://openalex.org/P4310320439","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Computer Society","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computing in Cardiology Conference (CinC)","raw_type":"proceedings-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2794904257.pdf","grobid_xml":"https://content.openalex.org/works/W2794904257.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W121250741","https://openalex.org/W2037707962","https://openalex.org/W2045202588","https://openalex.org/W2061651758","https://openalex.org/W2071537189","https://openalex.org/W2072672465","https://openalex.org/W2077352542","https://openalex.org/W2090696765","https://openalex.org/W2101711656","https://openalex.org/W2124916848","https://openalex.org/W2130321115","https://openalex.org/W2130680932","https://openalex.org/W2144148024","https://openalex.org/W2150113001","https://openalex.org/W2167728992","https://openalex.org/W2304661108","https://openalex.org/W2565076951","https://openalex.org/W7073538202"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2898370298","https://openalex.org/W4292492973","https://openalex.org/W2744391499","https://openalex.org/W3120461830","https://openalex.org/W4230250635","https://openalex.org/W3041790586","https://openalex.org/W2018879842","https://openalex.org/W3144504424"],"abstract_inverted_index":{"Hyperkalaemic":[0,44],"conditions":[1],"belonged":[2],"to":[3,28,47,53,79],"one":[4],"of":[5,17,23,37,83,91,104],"changes":[6],"brought":[7],"by":[8,42],"ischemia.":[9],"Hyperkalaemia":[10],"is":[11],"identified":[12],"as":[13,101],"a":[14,102],"major":[15],"determinant":[16],"ventricular":[18],"arrhythmias.":[19],"Onedimensional":[20],"fiber":[21],"model":[22],"transmural":[24],"cells":[25,49],"was":[26,50],"used":[27],"simulate":[29],"regional":[30,106],"hyperkalaemic":[31],"conditions.":[32],"We":[33],"investigated":[34],"the":[35,81,89],"process":[36,90],"alternating":[38,96],"conduction":[39,56,62,97],"developing":[40],"induced":[41],"hyperkalaemia.":[43],"region":[45],"closer":[46],"Endo":[48],"more":[51],"likely":[52],"cause":[54],"2:1":[55],"blocks.":[57],"Increased":[58],"depolarization":[59,84],"time":[60],"and":[61],"delay":[63],"were":[64],"essential":[65],"for":[66],"blocks":[67],"developing.":[68],"The":[69],"L-type":[70],"calcium":[71],"current":[72],"(I":[73],"CaL":[74],")":[75],"became":[76],"too":[77],"small":[78],"maintain":[80],"phase":[82],"every":[85],"other":[86],"beat":[87],"during":[88],"conduction.":[92],"Alternans":[93],"associated":[94],"with":[95],"could":[98],"be":[99],"considered":[100],"marker":[103],"acute":[105],"ischemia/hyperkalaemia.":[107]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
