{"id":"https://openalex.org/W4213154744","doi":"https://doi.org/10.21105/joss.03951","title":"OpenCADD-KLIFS: A Python package to fetch kinase data from the KLIFS database","display_name":"OpenCADD-KLIFS: A Python package to fetch kinase data from the KLIFS database","publication_year":2022,"publication_date":"2022-02-17","ids":{"openalex":"https://openalex.org/W4213154744","doi":"https://doi.org/10.21105/joss.03951"},"language":"en","primary_location":{"id":"doi:10.21105/joss.03951","is_oa":true,"landing_page_url":"https://doi.org/10.21105/joss.03951","pdf_url":"https://joss.theoj.org/papers/10.21105/joss.03951.pdf","source":{"id":"https://openalex.org/S4210214273","display_name":"The Journal of Open Source Software","issn_l":"2475-9066","issn":["2475-9066"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315853","host_organization_name":"Open Journals","host_organization_lineage":["https://openalex.org/P4310315853"],"host_organization_lineage_names":["Open Journals"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Open Source Software","raw_type":"journal-article"},"type":"software-paper","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://joss.theoj.org/papers/10.21105/joss.03951.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071001630","display_name":"Dominique Sydow","orcid":"https://orcid.org/0000-0003-4205-8705"},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dominique Sydow","raw_affiliation_strings":["In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charit -Universittsmedizin Berlin, corporate member of Freie Universitt Berlin and Humboldt-Universitt zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany","In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charit\u00e9 -Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0003-4205-8705","affiliations":[{"raw_affiliation_string":"In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charit -Universittsmedizin Berlin, corporate member of Freie Universitt Berlin and Humboldt-Universitt zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany","institution_ids":["https://openalex.org/I39343248"]},{"raw_affiliation_string":"In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charit\u00e9 -Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany","institution_ids":["https://openalex.org/I39343248","https://openalex.org/I75951250","https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101741282","display_name":"Jaime Rodr\u0131\u0301guez-Guerra","orcid":"https://orcid.org/0000-0001-8974-1566"},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jaime Rodr\u00edguez-Guerra","raw_affiliation_strings":["In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charit\u00e9 -Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0001-8974-1566","affiliations":[{"raw_affiliation_string":"In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charit\u00e9 -Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany","institution_ids":["https://openalex.org/I39343248","https://openalex.org/I75951250","https://openalex.org/I7877124"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057416678","display_name":"Andrea Volkamer","orcid":"https://orcid.org/0000-0002-3760-580X"},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andrea Volkamer","raw_affiliation_strings":["In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charit -Universittsmedizin Berlin, corporate member of Freie Universitt Berlin and Humboldt-Universitt zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany","In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charit\u00e9 -Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0002-3760-580X","affiliations":[{"raw_affiliation_string":"In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charit -Universittsmedizin Berlin, corporate member of Freie Universitt Berlin and Humboldt-Universitt zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany","institution_ids":["https://openalex.org/I39343248"]},{"raw_affiliation_string":"In Silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charit\u00e9 -Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany","institution_ids":["https://openalex.org/I39343248","https://openalex.org/I75951250","https://openalex.org/I7877124"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"70","first_page":"3951","last_page":"3951"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9909999966621399,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9902999997138977,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/python","display_name":"Python (programming language)","score":0.69545578956604},{"id":"https://openalex.org/keywords/fetch","display_name":"Fetch","score":0.6484602689743042},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.6058935523033142},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5927994251251221},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.30680081248283386},{"id":"https://openalex.org/keywords/geology","display_name":"Geology","score":0.0957036018371582},{"id":"https://openalex.org/keywords/oceanography","display_name":"Oceanography","score":0.046540766954422}],"concepts":[{"id":"https://openalex.org/C519991488","wikidata":"https://www.wikidata.org/wiki/Q28865","display_name":"Python (programming language)","level":2,"score":0.69545578956604},{"id":"https://openalex.org/C131918245","wikidata":"https://www.wikidata.org/wiki/Q1409090","display_name":"Fetch","level":2,"score":0.6484602689743042},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.6058935523033142},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5927994251251221},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.30680081248283386},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0957036018371582},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.046540766954422}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21105/joss.03951","is_oa":true,"landing_page_url":"https://doi.org/10.21105/joss.03951","pdf_url":"https://joss.theoj.org/papers/10.21105/joss.03951.pdf","source":{"id":"https://openalex.org/S4210214273","display_name":"The Journal of Open Source Software","issn_l":"2475-9066","issn":["2475-9066"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315853","host_organization_name":"Open Journals","host_organization_lineage":["https://openalex.org/P4310315853"],"host_organization_lineage_names":["Open Journals"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Open Source Software","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.21105/joss.03951","is_oa":true,"landing_page_url":"https://doi.org/10.21105/joss.03951","pdf_url":"https://joss.theoj.org/papers/10.21105/joss.03951.pdf","source":{"id":"https://openalex.org/S4210214273","display_name":"The Journal of Open Source Software","issn_l":"2475-9066","issn":["2475-9066"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315853","host_organization_name":"Open Journals","host_organization_lineage":["https://openalex.org/P4310315853"],"host_organization_lineage_names":["Open Journals"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Open Source Software","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4213154744.pdf","grobid_xml":"https://content.openalex.org/works/W4213154744.grobid-xml"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W1975436091","https://openalex.org/W2582341846","https://openalex.org/W2621473099","https://openalex.org/W2764282369","https://openalex.org/W2782910903","https://openalex.org/W2797137144","https://openalex.org/W2900090807","https://openalex.org/W3093634533","https://openalex.org/W3161074857","https://openalex.org/W6969259846"],"related_works":["https://openalex.org/W1906486629","https://openalex.org/W4318619745","https://openalex.org/W3021560500","https://openalex.org/W2166247150","https://openalex.org/W4243252198","https://openalex.org/W656686947","https://openalex.org/W3007645298","https://openalex.org/W2584070953","https://openalex.org/W3160881136","https://openalex.org/W1825954513"],"abstract_inverted_index":{"Protein":[0],"kinases":[1,18,47,76],"are":[2],"involved":[3],"in":[4,14,36],"most":[5],"aspects":[6],"of":[7,54,88],"cell":[8],"life":[9],"due":[10],"to":[11,50,94],"their":[12],"role":[13],"signal":[15],"transduction.":[16],"Dysregulated":[17],"can":[19],"cause":[20],"severe":[21],"diseases":[22],"such":[23],"as":[24],"cancer,":[25],"inflammation,":[26],"and":[27,71,77],"neurodegeneration,":[28],"which":[29,67],"has":[30,48],"made":[31],"them":[32,62],"a":[33,85],"frequent":[34],"target":[35],"drug":[37],"discovery":[38],"for":[39],"the":[40,64,89],"last":[41],"decades":[42],"The":[43,80],"immense":[44],"research":[45],"on":[46,69,75],"led":[49],"an":[51],"increasing":[52],"amount":[53],"kinase":[55,97],"resources":[56],"(Kooistra":[57],"&":[58],"Volkamer,":[59],"2017).":[60],"Among":[61],"is":[63],"KLIFS":[65,90],"database,":[66],"focuses":[68],"storing":[70],"analyzing":[72],"structural":[73],"data":[74,91],"interacting":[78],"ligands":[79],"OpenCADD-KLIFS":[81],"Python":[82],"module":[83],"offers":[84],"convenient":[86],"integration":[87],"into":[92],"workflows":[93],"facilitate":[95],"computational":[96],"research.":[98]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}