{"id":"https://openalex.org/W2295768910","doi":"https://doi.org/10.15439/2015f399","title":"Predicting Thyrotoxicosis in Patients Using a Set of Routine Tests: Adding their Rate of Annual Time-Series Variations to Self-Organizing Map-Based Predictive Model Improves Diagnostic Accuracy","display_name":"Predicting Thyrotoxicosis in Patients Using a Set of Routine Tests: Adding their Rate of Annual Time-Series Variations to Self-Organizing Map-Based Predictive Model Improves Diagnostic Accuracy","publication_year":2015,"publication_date":"2015-10-11","ids":{"openalex":"https://openalex.org/W2295768910","doi":"https://doi.org/10.15439/2015f399","mag":"2295768910"},"language":"en","primary_location":{"id":"doi:10.15439/2015f399","is_oa":true,"landing_page_url":"https://doi.org/10.15439/2015f399","pdf_url":"https://2024.fedcsis.org/proceedings/2015/pliks/399.pdf","source":{"id":"https://openalex.org/S4220651875","display_name":"Annals of Computer Science and Information Systems","issn_l":"2300-5963","issn":["2300-5963"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":"https://openalex.org/P4310317484","host_organization_name":"Polskie Towarzystwo Informatyczne","host_organization_lineage":["https://openalex.org/P4310317484"],"host_organization_lineage_names":["Polskie Towarzystwo Informatyczne"],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Computer Science and Information Systems","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://2024.fedcsis.org/proceedings/2015/pliks/399.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009746444","display_name":"Sorama Aoki","orcid":"https://orcid.org/0000-0002-1148-2688"},"institutions":[{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]},{"id":"https://openalex.org/I882656400","display_name":"Komatsu (Japan)","ror":"https://ror.org/03s23ay81","country_code":"JP","type":"company","lineage":["https://openalex.org/I882656400"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Sorama Aoki","raw_affiliation_strings":["Medical and Pharmaceutical Information Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical and Pharmaceutical Information Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan","institution_ids":["https://openalex.org/I85324120","https://openalex.org/I882656400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059259805","display_name":"Sono Nishizaka","orcid":null},"institutions":[{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]},{"id":"https://openalex.org/I882656400","display_name":"Komatsu (Japan)","ror":"https://ror.org/03s23ay81","country_code":"JP","type":"company","lineage":["https://openalex.org/I882656400"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Sono Nishizaka","raw_affiliation_strings":["Medical and Pharmaceutical Information Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical and Pharmaceutical Information Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan","institution_ids":["https://openalex.org/I85324120","https://openalex.org/I882656400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101608370","display_name":"Kenichi Sato","orcid":"https://orcid.org/0000-0002-3909-3326"},"institutions":[{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]},{"id":"https://openalex.org/I882656400","display_name":"Komatsu (Japan)","ror":"https://ror.org/03s23ay81","country_code":"JP","type":"company","lineage":["https://openalex.org/I882656400"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenichi Sato","raw_affiliation_strings":["Medical and Pharmaceutical Information Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical and Pharmaceutical Information Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan","institution_ids":["https://openalex.org/I85324120","https://openalex.org/I882656400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019016117","display_name":"Kenji Hoshi","orcid":"https://orcid.org/0000-0001-9531-6005"},"institutions":[{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]},{"id":"https://openalex.org/I882656400","display_name":"Komatsu (Japan)","ror":"https://ror.org/03s23ay81","country_code":"JP","type":"company","lineage":["https://openalex.org/I882656400"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenji Hoshi","raw_affiliation_strings":["Medical and Pharmaceutical Information Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical and Pharmaceutical Information Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan","institution_ids":["https://openalex.org/I85324120","https://openalex.org/I882656400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108430876","display_name":"Junko Kawakami","orcid":null},"institutions":[{"id":"https://openalex.org/I882656400","display_name":"Komatsu (Japan)","ror":"https://ror.org/03s23ay81","country_code":"JP","type":"company","lineage":["https://openalex.org/I882656400"]},{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Junko Kawakami","raw_affiliation_strings":["Medical and Pharmaceutical Information Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical and Pharmaceutical Information Science, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan","institution_ids":["https://openalex.org/I85324120","https://openalex.org/I882656400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102057526","display_name":"Kouki Mori","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kouki Mori","raw_affiliation_strings":["Center for Health Promotion, JR Sendai Hospital Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Health Promotion, JR Sendai Hospital Sendai, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113592184","display_name":"Yoshinori Nakagawa","orcid":"https://orcid.org/0009-0006-6126-6250"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yoshinori Nakagawa","raw_affiliation_strings":["Sendai Thyroid Clinic Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sendai Thyroid Clinic Sendai, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087726338","display_name":"Wataru Hida","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wataru Hida","raw_affiliation_strings":["Department of Health Supervision, Tohoku Kosai Hospital Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Supervision, Tohoku Kosai Hospital Sendai, Japan","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110005941","display_name":"Katsumi Yoshida","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katsumi Yoshida","raw_affiliation_strings":["Department of Health Supervision, Tohoku Kosai Hospital Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Supervision, Tohoku Kosai Hospital Sendai, Japan","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5009746444"],"corresponding_institution_ids":["https://openalex.org/I85324120","https://openalex.org/I882656400"],"apc_list":null,"apc_paid":null,"fwci":8.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.95744681,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"6","issue":null,"first_page":"3","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.958299994468689,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.9513000249862671,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/false-positive-paradox","display_name":"False positive paradox","score":0.8161662817001343},{"id":"https://openalex.org/keywords/series","display_name":"Series (stratigraphy)","score":0.6143025159835815},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.555317223072052},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5260434150695801},{"id":"https://openalex.org/keywords/data-set","display_name":"Data set","score":0.4820469319820404},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.46770426630973816},{"id":"https://openalex.org/keywords/true-positive-rate","display_name":"True positive rate","score":0.44787225127220154},{"id":"https://openalex.org/keywords/self-organizing-map","display_name":"Self-organizing map","score":0.41353681683540344},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.40743309259414673},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.39994415640830994},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.3219299018383026},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.18243703246116638}],"concepts":[{"id":"https://openalex.org/C64869954","wikidata":"https://www.wikidata.org/wiki/Q1859747","display_name":"False positive paradox","level":2,"score":0.8161662817001343},{"id":"https://openalex.org/C143724316","wikidata":"https://www.wikidata.org/wiki/Q312468","display_name":"Series (stratigraphy)","level":2,"score":0.6143025159835815},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.555317223072052},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5260434150695801},{"id":"https://openalex.org/C58489278","wikidata":"https://www.wikidata.org/wiki/Q1172284","display_name":"Data set","level":2,"score":0.4820469319820404},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.46770426630973816},{"id":"https://openalex.org/C2989486834","wikidata":"https://www.wikidata.org/wiki/Q3808900","display_name":"True positive rate","level":2,"score":0.44787225127220154},{"id":"https://openalex.org/C111168008","wikidata":"https://www.wikidata.org/wiki/Q1136838","display_name":"Self-organizing map","level":3,"score":0.41353681683540344},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.40743309259414673},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.39994415640830994},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.3219299018383026},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.18243703246116638},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.15439/2015f399","is_oa":true,"landing_page_url":"https://doi.org/10.15439/2015f399","pdf_url":"https://2024.fedcsis.org/proceedings/2015/pliks/399.pdf","source":{"id":"https://openalex.org/S4220651875","display_name":"Annals of Computer Science and Information Systems","issn_l":"2300-5963","issn":["2300-5963"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":"https://openalex.org/P4310317484","host_organization_name":"Polskie Towarzystwo Informatyczne","host_organization_lineage":["https://openalex.org/P4310317484"],"host_organization_lineage_names":["Polskie Towarzystwo Informatyczne"],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Computer Science and Information Systems","raw_type":"proceedings-article"},{"id":"pmh:oai:doaj.org/article:e1b806a8f71d47d88f12b79ad7a82991","is_oa":false,"landing_page_url":"https://doaj.org/article/e1b806a8f71d47d88f12b79ad7a82991","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Annals of computer science and information systems, Vol 6, Pp 3-9 (2015)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.15439/2015f399","is_oa":true,"landing_page_url":"https://doi.org/10.15439/2015f399","pdf_url":"https://2024.fedcsis.org/proceedings/2015/pliks/399.pdf","source":{"id":"https://openalex.org/S4220651875","display_name":"Annals of Computer Science and Information Systems","issn_l":"2300-5963","issn":["2300-5963"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":"https://openalex.org/P4310317484","host_organization_name":"Polskie Towarzystwo Informatyczne","host_organization_lineage":["https://openalex.org/P4310317484"],"host_organization_lineage_names":["Polskie Towarzystwo Informatyczne"],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Computer Science and Information Systems","raw_type":"proceedings-article"},"sustainable_development_goals":[{"score":0.7200000286102295,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1509711742","display_name":"Development of the new method to assist diagnosing thyroid dysfunction adopting a combination of routine test data that was already measured during health-checkup, and its clinical application","funder_award_id":"23590811","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7628028789","display_name":"New method for aiding detection of abnormal thyroid function in patients making use of set of routine tests – applying it in screening during general health check-ups or visiting hospitals","funder_award_id":"26460777","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2295768910.pdf","grobid_xml":"https://content.openalex.org/works/W2295768910.grobid-xml"},"referenced_works_count":6,"referenced_works":["https://openalex.org/W1978362173","https://openalex.org/W1986432079","https://openalex.org/W2028907465","https://openalex.org/W2096524107","https://openalex.org/W2111051539","https://openalex.org/W2140936682"],"related_works":["https://openalex.org/W2027184711","https://openalex.org/W1557094818","https://openalex.org/W4287692494","https://openalex.org/W3129715955","https://openalex.org/W3047594718","https://openalex.org/W2953243682","https://openalex.org/W3027053746","https://openalex.org/W4299651861","https://openalex.org/W4386222044","https://openalex.org/W2099261052"],"abstract_inverted_index":{"Difficulties":[0],"have":[1],"been":[2],"associated":[3],"with":[4,8],"accurately":[5],"diagnosing":[6],"patients":[7],"thyroid":[9,14],"dysfunction":[10],"(PTD);":[11],"however,":[12],"measuring":[13],"hormone":[15],"levels":[16],"in":[17,69,75,88,118],"all":[18],"individuals":[19],"is":[20],"challenging.":[21],"We":[22,91,108],"successfully":[23],"constructed":[24,92],"a":[25,36],"prediction":[26],"model":[27,80],"for":[28],"PTD":[29,47,103],"by":[30,81],"adopting":[31],"pattern":[32],"recognition":[33],"methods":[34],"using":[35,48,96],"combination":[37],"of":[38,85,101,113,129,138],"six":[39],"routine":[40,70,89],"laboratory":[41],"tests,":[42],"and":[43,104,124],"identified":[44],"21":[45],"new":[46,140],"our":[49,119,139],"screening":[50],"method,":[51],"which":[52],"was":[53],"executed":[54],"at":[55],"two":[56],"health":[57],"check-up":[58],"centers.":[59],"In":[60],"the":[61,79,83,97,111,127,136],"present":[62],"study,":[63],"we":[64],"newly":[65],"introduced":[66],"time-series":[67,98],"variations":[68],"tests":[71],"as":[72],"additional":[73],"parameters":[74],"order":[76],"to":[77],"develop":[78],"eliminating":[82],"influence":[84],"individual":[86],"differences":[87],"tests.":[90],"self-organizing":[93],"maps":[94],"(SOM)":[95],"traceable":[99],"data":[100],"13":[102],"45":[105],"healthy":[106],"individuals.":[107],"then":[109],"investigated":[110],"locations":[112],"140":[114],"projected":[115],"false":[116,130],"positives":[117,131],"previous":[120],"study":[121],"on":[122],"SOM":[123],"found":[125],"that":[126],"number":[128],"markedly":[132],"decreased,":[133],"thereby":[134],"demonstrating":[135],"progression":[137],"model.":[141]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}