{"id":"https://openalex.org/W4236549833","doi":"https://doi.org/10.15302/j-qb-021-0262","title":"Phase separation in synthetic biology","display_name":"Phase separation in synthetic biology","publication_year":2021,"publication_date":"2021-07-30","ids":{"openalex":"https://openalex.org/W4236549833","doi":"https://doi.org/10.15302/j-qb-021-0262"},"language":"en","primary_location":{"id":"doi:10.15302/j-qb-021-0262","is_oa":true,"landing_page_url":"https://doi.org/10.15302/j-qb-021-0262","pdf_url":"https://journal.hep.com.cn/qb/EN/PDF/10.15302/J-QB-021-0262","source":{"id":"https://openalex.org/S4210172333","display_name":"Quantitative Biology","issn_l":"2095-4689","issn":["2095-4689","2095-4697"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quantitative Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://journal.hep.com.cn/qb/EN/PDF/10.15302/J-QB-021-0262","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5093452849","display_name":"Shi Shuyu","orcid":null},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shi Shuyu","raw_affiliation_strings":["<!--1--> Undergraduate Program of Medicine Peking University Third Hospital Beijing 100191 China","1. Undergraduate Program of Medicine, Peking University Third Hospital, Beijing 100191, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--1--> Undergraduate Program of Medicine Peking University Third Hospital Beijing 100191 China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210141942"]},{"raw_affiliation_string":"1. Undergraduate Program of Medicine, Peking University Third Hospital, Beijing 100191, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210141942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101901037","display_name":"Wen Si","orcid":"https://orcid.org/0000-0002-5095-9573"},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210160507","display_name":"Center for Life Sciences","ror":"https://ror.org/05kje8j93","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570","https://openalex.org/I4210160507","https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Si Wen","raw_affiliation_strings":["<!--2--> Academy for Advanced Interdisciplinary Studies Peking University Beijing 100871 China","2. Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--2--> Academy for Advanced Interdisciplinary Studies Peking University Beijing 100871 China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210160507"]},{"raw_affiliation_string":"2. Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093452850","display_name":"Ouyang Xiaoyi","orcid":null},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ouyang Xiaoyi","raw_affiliation_strings":["<!--3--> School of Physics Peking University Beijing 100871 China","3. School of Physics, Peking University, Beijing 100871, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--3--> School of Physics Peking University Beijing 100871 China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"3. School of Physics, Peking University, Beijing 100871, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"last","author":{"id":null,"display_name":"Wei Ping","orcid":null},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]},{"id":"https://openalex.org/I4210160507","display_name":"Center for Life Sciences","ror":"https://ror.org/05kje8j93","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570","https://openalex.org/I4210160507","https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Ping","raw_affiliation_strings":["<!--4--> Center for Quantitative Biology Academy for Advanced Interdisciplinary Studies Peking University Beijing 100871 China","<!--5--> Center for Cell and Gene Circuit Design CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China","5. Center for Cell and Gene Circuit Design, CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China","4. Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--4--> Center for Quantitative Biology Academy for Advanced Interdisciplinary Studies Peking University Beijing 100871 China","institution_ids":["https://openalex.org/I4210160507"]},{"raw_affiliation_string":"<!--5--> Center for Cell and Gene Circuit Design CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China","institution_ids":["https://openalex.org/I4210145761"]},{"raw_affiliation_string":"5. Center for Cell and Gene Circuit Design, CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China","institution_ids":["https://openalex.org/I4210145761"]},{"raw_affiliation_string":"4. Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China","institution_ids":["https://openalex.org/I20231570"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.15347204,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"9","issue":"4","first_page":"378","last_page":"399"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9413999915122986,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9380999803543091,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/synthetic-biology","display_name":"Synthetic biology","score":0.7877304553985596},{"id":"https://openalex.org/keywords/separation","display_name":"Separation (statistics)","score":0.608641505241394},{"id":"https://openalex.org/keywords/phase","display_name":"Phase (matter)","score":0.5435000658035278},{"id":"https://openalex.org/keywords/separation-method","display_name":"Separation method","score":0.4274277687072754},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.374284029006958},{"id":"https://openalex.org/keywords/biochemical-engineering","display_name":"Biochemical engineering","score":0.3510622978210449},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3427320122718811},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.31675535440444946},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3160368800163269},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.27507686614990234},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.10740125179290771},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.09246930480003357},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08058929443359375}],"concepts":[{"id":"https://openalex.org/C191908910","wikidata":"https://www.wikidata.org/wiki/Q862838","display_name":"Synthetic biology","level":2,"score":0.7877304553985596},{"id":"https://openalex.org/C2776061190","wikidata":"https://www.wikidata.org/wiki/Q7451805","display_name":"Separation (statistics)","level":2,"score":0.608641505241394},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.5435000658035278},{"id":"https://openalex.org/C3018256011","wikidata":"https://www.wikidata.org/wiki/Q898987","display_name":"Separation method","level":2,"score":0.4274277687072754},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.374284029006958},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.3510622978210449},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3427320122718811},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.31675535440444946},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3160368800163269},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27507686614990234},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.10740125179290771},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.09246930480003357},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08058929443359375},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.15302/j-qb-021-0262","is_oa":true,"landing_page_url":"https://doi.org/10.15302/j-qb-021-0262","pdf_url":"https://journal.hep.com.cn/qb/EN/PDF/10.15302/J-QB-021-0262","source":{"id":"https://openalex.org/S4210172333","display_name":"Quantitative Biology","issn_l":"2095-4689","issn":["2095-4689","2095-4697"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quantitative Biology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.15302/j-qb-021-0262","is_oa":true,"landing_page_url":"https://doi.org/10.15302/j-qb-021-0262","pdf_url":"https://journal.hep.com.cn/qb/EN/PDF/10.15302/J-QB-021-0262","source":{"id":"https://openalex.org/S4210172333","display_name":"Quantitative Biology","issn_l":"2095-4689","issn":["2095-4689","2095-4697"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quantitative Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3354268643","display_name":null,"funder_award_id":"31622022","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6486624941","display_name":null,"funder_award_id":"31470819","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4236549833.pdf","grobid_xml":"https://content.openalex.org/works/W4236549833.grobid-xml"},"referenced_works_count":177,"referenced_works":["https://openalex.org/W285093818","https://openalex.org/W834977926","https://openalex.org/W1509466986","https://openalex.org/W1551786110","https://openalex.org/W1823263094","https://openalex.org/W1834588461","https://openalex.org/W1837454973","https://openalex.org/W1854281301","https://openalex.org/W1912455695","https://openalex.org/W1952608303","https://openalex.org/W1964478423","https://openalex.org/W1976603396","https://openalex.org/W1978210814","https://openalex.org/W1990171977","https://openalex.org/W1993084790","https://openalex.org/W2002373110","https://openalex.org/W2014185980","https://openalex.org/W2017593971","https://openalex.org/W2031087599","https://openalex.org/W2034611537","https://openalex.org/W2036008741","https://openalex.org/W2036459564","https://openalex.org/W2038052314","https://openalex.org/W2044821390","https://openalex.org/W2054352933","https://openalex.org/W2063534825","https://openalex.org/W2067427915","https://openalex.org/W2071262787","https://openalex.org/W2078821795","https://openalex.org/W2078929441","https://openalex.org/W2083431317","https://openalex.org/W2085978470","https://openalex.org/W2087786655","https://openalex.org/W2090429649","https://openalex.org/W2108663777","https://openalex.org/W2109879947","https://openalex.org/W2111796925","https://openalex.org/W2112940322","https://openalex.org/W2120156669","https://openalex.org/W2125272201","https://openalex.org/W2128314421","https://openalex.org/W2139066576","https://openalex.org/W2144588155","https://openalex.org/W2145200068","https://openalex.org/W2146151986","https://openalex.org/W2146634463","https://openalex.org/W2146926661","https://openalex.org/W2147516046","https://openalex.org/W2164995160","https://openalex.org/W2168639701","https://openalex.org/W2168958678","https://openalex.org/W2172098255","https://openalex.org/W2192789229","https://openalex.org/W2222857089","https://openalex.org/W2235988210","https://openalex.org/W2313094648","https://openalex.org/W2396545524","https://openalex.org/W2402791934","https://openalex.org/W2403526287","https://openalex.org/W2461977200","https://openalex.org/W2475032329","https://openalex.org/W2509111410","https://openalex.org/W2509859037","https://openalex.org/W2510545519","https://openalex.org/W2516935932","https://openalex.org/W2517158470","https://openalex.org/W2517195794","https://openalex.org/W2553996574","https://openalex.org/W2566521622","https://openalex.org/W2590568317","https://openalex.org/W2593862218","https://openalex.org/W2594707272","https://openalex.org/W2615201923","https://openalex.org/W2694038906","https://openalex.org/W2722642526","https://openalex.org/W2734958598","https://openalex.org/W2742396220","https://openalex.org/W2743471889","https://openalex.org/W2745326990","https://openalex.org/W2750569114","https://openalex.org/W2755105920","https://openalex.org/W2756821926","https://openalex.org/W2758396775","https://openalex.org/W2765486298","https://openalex.org/W2782081342","https://openalex.org/W2782130029","https://openalex.org/W2784297130","https://openalex.org/W2785420592","https://openalex.org/W2786469974","https://openalex.org/W2788827529","https://openalex.org/W2790286335","https://openalex.org/W2791574316","https://openalex.org/W2792129356","https://openalex.org/W2792541660","https://openalex.org/W2794654572","https://openalex.org/W2795649462","https://openalex.org/W2802390799","https://openalex.org/W2802667264","https://openalex.org/W2803508083","https://openalex.org/W2804270751","https://openalex.org/W2808121690","https://openalex.org/W2809057270","https://openalex.org/W2810246680","https://openalex.org/W2810350665","https://openalex.org/W2810866092","https://openalex.org/W2854081253","https://openalex.org/W2884216445","https://openalex.org/W2886239953","https://openalex.org/W2887353309","https://openalex.org/W2893743826","https://openalex.org/W2894343849","https://openalex.org/W2901209536","https://openalex.org/W2901758876","https://openalex.org/W2902026154","https://openalex.org/W2902553806","https://openalex.org/W2902709687","https://openalex.org/W2903264039","https://openalex.org/W2904764917","https://openalex.org/W2908663603","https://openalex.org/W2914208030","https://openalex.org/W2914618466","https://openalex.org/W2914907359","https://openalex.org/W2921134191","https://openalex.org/W2921733160","https://openalex.org/W2922246560","https://openalex.org/W2923609388","https://openalex.org/W2931894123","https://openalex.org/W2942604302","https://openalex.org/W2943858683","https://openalex.org/W2948379537","https://openalex.org/W2949837580","https://openalex.org/W2952516695","https://openalex.org/W2952667761","https://openalex.org/W2953749471","https://openalex.org/W2953933961","https://openalex.org/W2955829592","https://openalex.org/W2965952834","https://openalex.org/W2966567728","https://openalex.org/W2971594646","https://openalex.org/W2973290848","https://openalex.org/W2973602800","https://openalex.org/W2975196800","https://openalex.org/W2977849281","https://openalex.org/W2978569560","https://openalex.org/W2979404777","https://openalex.org/W2979601486","https://openalex.org/W2980597982","https://openalex.org/W2980646921","https://openalex.org/W2981071222","https://openalex.org/W2981272131","https://openalex.org/W2988445595","https://openalex.org/W2991067665","https://openalex.org/W2997051198","https://openalex.org/W2998775495","https://openalex.org/W3008231862","https://openalex.org/W3008604026","https://openalex.org/W3010423197","https://openalex.org/W3010929769","https://openalex.org/W3011599658","https://openalex.org/W3013781039","https://openalex.org/W3015118917","https://openalex.org/W3017715131","https://openalex.org/W3023602638","https://openalex.org/W3030627391","https://openalex.org/W3034018673","https://openalex.org/W3035241254","https://openalex.org/W3044505383","https://openalex.org/W3046158099","https://openalex.org/W3085471727","https://openalex.org/W3092508309","https://openalex.org/W3112669250","https://openalex.org/W3116814341","https://openalex.org/W3127276052","https://openalex.org/W3131479422","https://openalex.org/W3135639803","https://openalex.org/W3137617968","https://openalex.org/W4211125927"],"related_works":["https://openalex.org/W2120971204","https://openalex.org/W2166646476","https://openalex.org/W2530775458","https://openalex.org/W2626881661","https://openalex.org/W2140005900","https://openalex.org/W4367368619","https://openalex.org/W2361398959","https://openalex.org/W2693899803","https://openalex.org/W2384308427","https://openalex.org/W1593372860"],"abstract_inverted_index":{"Background":[0],"The":[1,153],"concept":[2],"of":[3,54,83,93,117,126,187,196],"phase":[4,24,55,68,84,94,110,127,136,151,189],"separation":[5,69,85,95,128,137,190],"has":[6],"been":[7],"used":[8,159],"to":[9,42,63,101,108,120],"describe":[10],"and":[11,38,47,105,112,124,145,149,173,183],"interpret":[12],"physicochemical":[13],"phenomena":[14],"in":[15,31,86,96,129,138,160],"biological":[16,48],"systems":[17],"for":[18,70],"decades.":[19],"Many":[20],"intracellular":[21],"macromolecules":[22],"undergo":[23],"separation,":[25,56,111],"where":[26],"it":[27],"plays":[28],"important":[29],"roles":[30],"gene":[32,169],"regulation,":[33],"cellular":[34],"signaling,":[35],"metabolic":[36,167],"reactions":[37],"so":[39],"on,":[40],"due":[41],"its":[43],"unique":[44],"dynamic":[45],"properties":[46],"effects.":[49],"As":[50],"the":[51,61,65,80,122,193],"noticeable":[52],"importance":[53],"pioneer":[57],"researchers":[58],"have":[59],"explored":[60],"possibility":[62],"introduce":[64],"synthetically":[66],"engineered":[67],"applicable":[71],"cell":[72],"function.":[73],"Results":[74],"In":[75],"this":[76,197],"article,":[77],"we":[78],"illustrated":[79],"application":[81],"value":[82],"synthetic":[87,103,130,139,188],"biology.":[88,131,140],"We":[89],"described":[90],"main":[91],"states":[92],"detail,":[97],"summarized":[98],"some":[99],"ways":[100],"implement":[102,135],"condensates":[104,156],"several":[106],"methods":[107],"regulate":[109,150],"provided":[113],"a":[114],"substantial":[115],"amount":[116],"identical":[118],"examples":[119],"illuminate":[121],"applications":[123],"perspectives":[125],"Conclusions":[132],"Multivalent":[133],"interactions":[134,147],"Small":[141],"molecules,":[142],"light":[143],"control":[144,186],"spontaneous":[146],"induce":[148],"separation.":[152],"sy":[154],"nthetic":[155],"are":[157],"widely":[158],"signal":[161],"amplifications,":[162],"designer":[163],"orthogonally":[164],"non\u2010membrane\u2010bound":[165],"organelles,":[166],"pathways,":[168],"regulations,":[170],"signaling":[171],"transductions":[172],"controllable":[174],"platforms.":[175],"Studies":[176],"on":[177],"quantitative":[178],"analysis,":[179],"more":[180],"standardized":[181],"modules":[182],"precise":[184],"spatiotemporal":[185],"may":[191],"promote":[192],"further":[194],"development":[195],"field.":[198]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3}],"updated_date":"2026-06-23T06:36:01.041984","created_date":"2025-10-10T00:00:00"}