{"id":"https://openalex.org/W2807864099","doi":"https://doi.org/10.1515/jib-2018-0009","title":"Mesoscopic Rigid Body Modelling of the Extracellular Matrix Self-Assembly","display_name":"Mesoscopic Rigid Body Modelling of the Extracellular Matrix Self-Assembly","publication_year":2018,"publication_date":"2018-06-01","ids":{"openalex":"https://openalex.org/W2807864099","doi":"https://doi.org/10.1515/jib-2018-0009","mag":"2807864099","pmid":"https://pubmed.ncbi.nlm.nih.gov/29886454"},"language":"en","primary_location":{"id":"doi:10.1515/jib-2018-0009","is_oa":true,"landing_page_url":"https://doi.org/10.1515/jib-2018-0009","pdf_url":"https://www.degruyter.com/document/doi/10.1515/jib-2018-0009/pdf","source":{"id":"https://openalex.org/S4393917359","display_name":"Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics","issn_l":"1432-4385","issn":["1432-4385","1613-4516"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Integrative Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.degruyter.com/document/doi/10.1515/jib-2018-0009/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020995546","display_name":"Hua Wong","orcid":"https://orcid.org/0000-0002-6362-7228"},"institutions":[{"id":"https://openalex.org/I4210125654","display_name":"Maison de la Simulation","ror":"https://ror.org/03jv6w209","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I195731000","https://openalex.org/I2738703131","https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I277688954","https://openalex.org/I4210113668","https://openalex.org/I4210125654","https://openalex.org/I4210159245"]},{"id":"https://openalex.org/I96226040","display_name":"Universit\u00e9 de Reims Champagne-Ardenne","ror":"https://ror.org/03hypw319","country_code":"FR","type":"education","lineage":["https://openalex.org/I96226040"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Hua Wong","raw_affiliation_strings":["Plateau de Mod\u00e9lisation Mol\u00e9culaire Multi-Echelle (P3M), Maison de la Simulation de Champagne-Ardenne (MaSCA) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plateau de Mod\u00e9lisation Mol\u00e9culaire Multi-Echelle (P3M), Maison de la Simulation de Champagne-Ardenne (MaSCA) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","institution_ids":["https://openalex.org/I96226040","https://openalex.org/I4210125654"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019467241","display_name":"Jessica Jonquet","orcid":"https://orcid.org/0000-0001-7420-7002"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4387155780","display_name":"Matrice Extracellulaire et Dynamique Cellulaire MEDyC","ror":"https://ror.org/017p6sq53","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4387155780","https://openalex.org/I96226040"]},{"id":"https://openalex.org/I96226040","display_name":"Universit\u00e9 de Reims Champagne-Ardenne","ror":"https://ror.org/03hypw319","country_code":"FR","type":"education","lineage":["https://openalex.org/I96226040"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jessica Pr\u00e9voteau-Jonquet","raw_affiliation_strings":["UMR URCA/CNRS 7369, Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), Equipe Mod\u00e9lisation et Imagerie Multi-Echelles (MIME) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UMR URCA/CNRS 7369, Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), Equipe Mod\u00e9lisation et Imagerie Multi-Echelles (MIME) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","institution_ids":["https://openalex.org/I96226040","https://openalex.org/I4387155780","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084564692","display_name":"St\u00e9phanie Baud","orcid":"https://orcid.org/0000-0002-4436-0652"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210125654","display_name":"Maison de la Simulation","ror":"https://ror.org/03jv6w209","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I195731000","https://openalex.org/I2738703131","https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I277688954","https://openalex.org/I4210113668","https://openalex.org/I4210125654","https://openalex.org/I4210159245"]},{"id":"https://openalex.org/I4387155780","display_name":"Matrice Extracellulaire et Dynamique Cellulaire MEDyC","ror":"https://ror.org/017p6sq53","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4387155780","https://openalex.org/I96226040"]},{"id":"https://openalex.org/I96226040","display_name":"Universit\u00e9 de Reims Champagne-Ardenne","ror":"https://ror.org/03hypw319","country_code":"FR","type":"education","lineage":["https://openalex.org/I96226040"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"St\u00e9phanie Baud","raw_affiliation_strings":["Plateau de Mod\u00e9lisation Mol\u00e9culaire Multi-Echelle (P3M), Maison de la Simulation de Champagne-Ardenne (MaSCA) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","UMR URCA/CNRS 7369, Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), Equipe Mod\u00e9lisation et Imagerie Multi-Echelles (MIME) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plateau de Mod\u00e9lisation Mol\u00e9culaire Multi-Echelle (P3M), Maison de la Simulation de Champagne-Ardenne (MaSCA) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","institution_ids":["https://openalex.org/I96226040","https://openalex.org/I4210125654"]},{"raw_affiliation_string":"UMR URCA/CNRS 7369, Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), Equipe Mod\u00e9lisation et Imagerie Multi-Echelles (MIME) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","institution_ids":["https://openalex.org/I96226040","https://openalex.org/I4387155780","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016118429","display_name":"Manuel Dauchez","orcid":"https://orcid.org/0000-0002-6743-7915"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210125654","display_name":"Maison de la Simulation","ror":"https://ror.org/03jv6w209","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I195731000","https://openalex.org/I2738703131","https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I277688954","https://openalex.org/I4210113668","https://openalex.org/I4210125654","https://openalex.org/I4210159245"]},{"id":"https://openalex.org/I4387155780","display_name":"Matrice Extracellulaire et Dynamique Cellulaire MEDyC","ror":"https://ror.org/017p6sq53","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4387155780","https://openalex.org/I96226040"]},{"id":"https://openalex.org/I96226040","display_name":"Universit\u00e9 de Reims Champagne-Ardenne","ror":"https://ror.org/03hypw319","country_code":"FR","type":"education","lineage":["https://openalex.org/I96226040"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Manuel Dauchez","raw_affiliation_strings":["Plateau de Mod\u00e9lisation Mol\u00e9culaire Multi-Echelle (P3M), Maison de la Simulation de Champagne-Ardenne (MaSCA) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","UMR URCA/CNRS 7369, Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), Equipe Mod\u00e9lisation et Imagerie Multi-Echelles (MIME) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plateau de Mod\u00e9lisation Mol\u00e9culaire Multi-Echelle (P3M), Maison de la Simulation de Champagne-Ardenne (MaSCA) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","institution_ids":["https://openalex.org/I96226040","https://openalex.org/I4210125654"]},{"raw_affiliation_string":"UMR URCA/CNRS 7369, Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), Equipe Mod\u00e9lisation et Imagerie Multi-Echelles (MIME) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","institution_ids":["https://openalex.org/I96226040","https://openalex.org/I4387155780","https://openalex.org/I1294671590"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012502452","display_name":"Nicolas Belloy","orcid":"https://orcid.org/0000-0002-6003-3184"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210125654","display_name":"Maison de la Simulation","ror":"https://ror.org/03jv6w209","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I195731000","https://openalex.org/I2738703131","https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I277688954","https://openalex.org/I4210113668","https://openalex.org/I4210125654","https://openalex.org/I4210159245"]},{"id":"https://openalex.org/I4387155780","display_name":"Matrice Extracellulaire et Dynamique Cellulaire MEDyC","ror":"https://ror.org/017p6sq53","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4387155780","https://openalex.org/I96226040"]},{"id":"https://openalex.org/I96226040","display_name":"Universit\u00e9 de Reims Champagne-Ardenne","ror":"https://ror.org/03hypw319","country_code":"FR","type":"education","lineage":["https://openalex.org/I96226040"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Nicolas Belloy","raw_affiliation_strings":["Plateau de Mod\u00e9lisation Mol\u00e9culaire Multi-Echelle (P3M), Maison de la Simulation de Champagne-Ardenne (MaSCA) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","UMR URCA/CNRS 7369, Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), Equipe Mod\u00e9lisation et Imagerie Multi-Echelles (MIME) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France"],"raw_orcid":"https://orcid.org/0000-0002-6003-3184","affiliations":[{"raw_affiliation_string":"Plateau de Mod\u00e9lisation Mol\u00e9culaire Multi-Echelle (P3M), Maison de la Simulation de Champagne-Ardenne (MaSCA) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","institution_ids":["https://openalex.org/I96226040","https://openalex.org/I4210125654"]},{"raw_affiliation_string":"UMR URCA/CNRS 7369, Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), Equipe Mod\u00e9lisation et Imagerie Multi-Echelles (MIME) , Universit\u00e9 de Reims Champagne-Ardenne , 51687 Reims Cedex 2 , France","institution_ids":["https://openalex.org/I96226040","https://openalex.org/I4387155780","https://openalex.org/I1294671590"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5012502452"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210125654","https://openalex.org/I4387155780","https://openalex.org/I96226040"],"apc_list":null,"apc_paid":null,"fwci":0.5882,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.63832785,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"15","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11737","display_name":"Advanced Materials and Mechanics","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mesoscopic-physics","display_name":"Mesoscopic physics","score":0.6738736033439636},{"id":"https://openalex.org/keywords/testbed","display_name":"Testbed","score":0.6159964799880981},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.594095766544342},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"Extracellular matrix","score":0.5778031945228577},{"id":"https://openalex.org/keywords/dissipative-particle-dynamics","display_name":"Dissipative particle dynamics","score":0.520366370677948},{"id":"https://openalex.org/keywords/virtual-reality","display_name":"Virtual reality","score":0.5099107027053833},{"id":"https://openalex.org/keywords/sandbox","display_name":"Sandbox (software development)","score":0.4987797737121582},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.4704899787902832},{"id":"https://openalex.org/keywords/matrix","display_name":"Matrix (chemical analysis)","score":0.45264649391174316},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.3745797872543335},{"id":"https://openalex.org/keywords/distributed-computing","display_name":"Distributed computing","score":0.32103538513183594},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.29896247386932373},{"id":"https://openalex.org/keywords/human\u2013computer-interaction","display_name":"Human\u2013computer interaction","score":0.280098021030426},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.2162564992904663},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.20680531859397888},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.14679616689682007},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.10430273413658142}],"concepts":[{"id":"https://openalex.org/C177731217","wikidata":"https://www.wikidata.org/wiki/Q2622244","display_name":"Mesoscopic physics","level":2,"score":0.6738736033439636},{"id":"https://openalex.org/C31395832","wikidata":"https://www.wikidata.org/wiki/Q1318674","display_name":"Testbed","level":2,"score":0.6159964799880981},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.594095766544342},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.5778031945228577},{"id":"https://openalex.org/C45594756","wikidata":"https://www.wikidata.org/wiki/Q5282784","display_name":"Dissipative particle dynamics","level":3,"score":0.520366370677948},{"id":"https://openalex.org/C194969405","wikidata":"https://www.wikidata.org/wiki/Q170519","display_name":"Virtual reality","level":2,"score":0.5099107027053833},{"id":"https://openalex.org/C167981075","wikidata":"https://www.wikidata.org/wiki/Q2667186","display_name":"Sandbox (software development)","level":2,"score":0.4987797737121582},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.4704899787902832},{"id":"https://openalex.org/C106487976","wikidata":"https://www.wikidata.org/wiki/Q685816","display_name":"Matrix (chemical analysis)","level":2,"score":0.45264649391174316},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3745797872543335},{"id":"https://openalex.org/C120314980","wikidata":"https://www.wikidata.org/wiki/Q180634","display_name":"Distributed computing","level":1,"score":0.32103538513183594},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.29896247386932373},{"id":"https://openalex.org/C107457646","wikidata":"https://www.wikidata.org/wiki/Q207434","display_name":"Human\u2013computer interaction","level":1,"score":0.280098021030426},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2162564992904663},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.20680531859397888},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14679616689682007},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.10430273413658142},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.0},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.0},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000076142","descriptor_name":"Virtual Reality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000076142","descriptor_name":"Virtual Reality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000076142","descriptor_name":"Virtual Reality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019812","descriptor_name":"Heparan Sulfate Proteoglycans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019812","descriptor_name":"Heparan Sulfate Proteoglycans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019812","descriptor_name":"Heparan Sulfate Proteoglycans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1515/jib-2018-0009","is_oa":true,"landing_page_url":"https://doi.org/10.1515/jib-2018-0009","pdf_url":"https://www.degruyter.com/document/doi/10.1515/jib-2018-0009/pdf","source":{"id":"https://openalex.org/S4393917359","display_name":"Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics","issn_l":"1432-4385","issn":["1432-4385","1613-4516"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Integrative Bioinformatics","raw_type":"journal-article"},{"id":"pmid:29886454","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29886454","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of integrative bioinformatics","raw_type":null},{"id":"pmh:oai:HAL:hal-01821593v1","is_oa":false,"landing_page_url":"https://hal.univ-reims.fr/hal-01821593","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Integrative Bioinformatics, 2018, ⟨10.1515/jib-2018-0009⟩","raw_type":"Journal articles"},{"id":"pmh:oai:doaj.org/article:a118cf72595a497189e07595a061c844","is_oa":true,"landing_page_url":"https://doaj.org/article/a118cf72595a497189e07595a061c844","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Integrative Bioinformatics, Vol 15, Iss 2, Pp 690-1 (2018)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:5327992","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6167044","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1515/jib-2018-0009","is_oa":true,"landing_page_url":"https://doi.org/10.1515/jib-2018-0009","pdf_url":"https://www.degruyter.com/document/doi/10.1515/jib-2018-0009/pdf","source":{"id":"https://openalex.org/S4393917359","display_name":"Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics","issn_l":"1432-4385","issn":["1432-4385","1613-4516"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Integrative Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2807864099.pdf","grobid_xml":"https://content.openalex.org/works/W2807864099.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1480522400","https://openalex.org/W1484342162","https://openalex.org/W1496520030","https://openalex.org/W1536187379","https://openalex.org/W1951218128","https://openalex.org/W1972325477","https://openalex.org/W1973976569","https://openalex.org/W1974035453","https://openalex.org/W1976837011","https://openalex.org/W1985023614","https://openalex.org/W2019681680","https://openalex.org/W2025733563","https://openalex.org/W2025747372","https://openalex.org/W2029667189","https://openalex.org/W2037158103","https://openalex.org/W2050765870","https://openalex.org/W2059069305","https://openalex.org/W2064982295","https://openalex.org/W2073879953","https://openalex.org/W2080993455","https://openalex.org/W2084282121","https://openalex.org/W2092614862","https://openalex.org/W2102225353","https://openalex.org/W2126364917","https://openalex.org/W2130479394","https://openalex.org/W2131717149","https://openalex.org/W2138671124","https://openalex.org/W2147529042","https://openalex.org/W2152029916","https://openalex.org/W2154957104","https://openalex.org/W2163416267","https://openalex.org/W2187985754","https://openalex.org/W2188060873","https://openalex.org/W2211765673","https://openalex.org/W2256212941","https://openalex.org/W2408449031","https://openalex.org/W2418246280","https://openalex.org/W2738606079","https://openalex.org/W4238861095","https://openalex.org/W4246579642","https://openalex.org/W4297723481"],"related_works":["https://openalex.org/W2033352828","https://openalex.org/W2355810117","https://openalex.org/W3098313552","https://openalex.org/W70177500","https://openalex.org/W2546418048","https://openalex.org/W2076427967","https://openalex.org/W3212184609","https://openalex.org/W2105095141","https://openalex.org/W2004303496","https://openalex.org/W2187513553"],"abstract_inverted_index":{"The":[0],"extracellular":[1],"matrix":[2],"(ECM)":[3],"plays":[4],"an":[5],"important":[6],"role":[7,18],"in":[8,19,45,120,148,188],"supporting":[9],"tissues":[10],"and":[11,21,41,87,138,157],"organs.":[12],"It":[13],"even":[14],"has":[15],"a":[16,26,52,97,179,189],"functional":[17],"morphogenesis":[20],"differentiation":[22],"by":[23],"acting":[24],"as":[25,105,132],"source":[27],"of":[28,38,58,70,108,140,191],"active":[29],"molecules":[30,104,143],"(matrikines).":[31],"Many":[32],"diseases":[33],"are":[34,175],"linked":[35],"to":[36,100,113,177],"dysfunction":[37],"ECM":[39,72,117],"components":[40,118],"fragments":[42],"or":[43,78,135],"changes":[44],"their":[46],"structures.":[47],"As":[48],"such":[49,131],"it":[50],"is":[51,73],"prime":[53],"target":[54],"for":[55,61],"drugs.":[56],"Because":[57],"technological":[59],"limitations":[60],"observations":[62],"at":[63],"mesoscopic":[64,122],"scales,":[65],"the":[66,71,84,121,136,149,153,167,170],"precise":[67],"structural":[68],"organisation":[69],"not":[74],"well-known,":[75],"with":[76,91,162,184],"sparse":[77],"fuzzy":[79],"experimental":[80],"observables.":[81],"Based":[82],"on":[83],"Unity3D":[85,154],"game":[86,155],"physics":[88],"engines,":[89],"along":[90],"rigid":[92,109],"body":[93],"dynamics,":[94],"we":[95,165],"propose":[96],"virtual":[98,158,181],"sandbox":[99,182],"model":[101],"large":[102,185],"biological":[103],"dynamic":[106],"chains":[107],"bodies":[110],"interacting":[111],"together":[112],"gain":[114],"insight":[115],"into":[116],"behaviour":[119],"range.":[123],"We":[124],"have":[125],"preliminary":[126],"results":[127],"showing":[128],"how":[129],"parameters":[130],"fibre":[133],"flexibility":[134],"nature":[137],"number":[139],"interactions":[141],"between":[142],"can":[144],"induce":[145],"different":[146],"structures":[147],"basement":[150],"membrane.":[151],"Using":[152],"engine":[156],"reality":[159],"headset":[160],"coupled":[161],"haptic":[163],"controllers,":[164],"immerse":[166],"user":[168],"inside":[169],"corresponding":[171],"simulation.":[172],"Untrained":[173],"users":[174],"able":[176],"navigate":[178],"complex":[180],"crowded":[183],"biomolecules":[186],"models":[187],"matter":[190],"seconds.":[192]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}