{"id":"https://openalex.org/W4200483735","doi":"https://doi.org/10.1515/bams-2021-0183","title":"Novel biomarker and drug delivery systems for theranostics\u00a0\u2013 extracellular vesicles","display_name":"Novel biomarker and drug delivery systems for theranostics\u00a0\u2013 extracellular vesicles","publication_year":2021,"publication_date":"2021-12-01","ids":{"openalex":"https://openalex.org/W4200483735","doi":"https://doi.org/10.1515/bams-2021-0183"},"language":"en","primary_location":{"id":"doi:10.1515/bams-2021-0183","is_oa":false,"landing_page_url":"https://doi.org/10.1515/bams-2021-0183","pdf_url":null,"source":{"id":"https://openalex.org/S2764861201","display_name":"Bio-Algorithms and Med-Systems","issn_l":"1895-9091","issn":["1895-9091","1896-530X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bio-Algorithms and Med-Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ruj.uj.edu.pl/xmlui/handle/item/289165","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090813957","display_name":"Ewa St\u0119pie\u0144","orcid":"https://orcid.org/0000-0003-3589-1715"},"institutions":[{"id":"https://openalex.org/I126596746","display_name":"Jagiellonian University","ror":"https://ror.org/03bqmcz70","country_code":"PL","type":"education","lineage":["https://openalex.org/I126596746"]},{"id":"https://openalex.org/I4210086947","display_name":"Institute of Physics","ror":"https://ror.org/000sfad56","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210086947","https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Ewa \u0141. St\u0119pie\u0144","raw_affiliation_strings":["M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University , Krakow , Poland","Theranostics Center, Jagiellonian University , Krak\u00f3w , Poland","Total-Body Jagiellonian-PET Laboratory, Jagiellonian University , Krak\u00f3w , Poland"],"raw_orcid":"https://orcid.org/0000-0003-3589-1715","affiliations":[{"raw_affiliation_string":"M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University , Krakow , Poland","institution_ids":["https://openalex.org/I126596746","https://openalex.org/I4210086947"]},{"raw_affiliation_string":"Theranostics Center, Jagiellonian University , Krak\u00f3w , Poland","institution_ids":["https://openalex.org/I126596746"]},{"raw_affiliation_string":"Total-Body Jagiellonian-PET Laboratory, Jagiellonian University , Krak\u00f3w , Poland","institution_ids":["https://openalex.org/I126596746"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008243968","display_name":"Carina Rz\u0105ca","orcid":"https://orcid.org/0000-0002-7288-383X"},"institutions":[{"id":"https://openalex.org/I126596746","display_name":"Jagiellonian University","ror":"https://ror.org/03bqmcz70","country_code":"PL","type":"education","lineage":["https://openalex.org/I126596746"]},{"id":"https://openalex.org/I4210086947","display_name":"Institute of Physics","ror":"https://ror.org/000sfad56","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210086947","https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Carina Rz\u0105ca","raw_affiliation_strings":["M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University , Krakow , Poland","Theranostics Center, Jagiellonian University , Krak\u00f3w , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University , Krakow , Poland","institution_ids":["https://openalex.org/I126596746","https://openalex.org/I4210086947"]},{"raw_affiliation_string":"Theranostics Center, Jagiellonian University , Krak\u00f3w , Poland","institution_ids":["https://openalex.org/I126596746"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038931314","display_name":"P. Moskal","orcid":"https://orcid.org/0000-0002-4229-3548"},"institutions":[{"id":"https://openalex.org/I126596746","display_name":"Jagiellonian University","ror":"https://ror.org/03bqmcz70","country_code":"PL","type":"education","lineage":["https://openalex.org/I126596746"]},{"id":"https://openalex.org/I4210086947","display_name":"Institute of Physics","ror":"https://ror.org/000sfad56","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210086947","https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Pawe\u0142 Moskal","raw_affiliation_strings":["M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University , Krakow , Poland","Theranostics Center, Jagiellonian University , Krak\u00f3w , Poland","Total-Body Jagiellonian-PET Laboratory, Jagiellonian University , Krak\u00f3w , Poland"],"raw_orcid":"https://orcid.org/0000-0002-4229-3548","affiliations":[{"raw_affiliation_string":"M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University , Krakow , Poland","institution_ids":["https://openalex.org/I126596746","https://openalex.org/I4210086947"]},{"raw_affiliation_string":"Theranostics Center, Jagiellonian University , Krak\u00f3w , Poland","institution_ids":["https://openalex.org/I126596746"]},{"raw_affiliation_string":"Total-Body Jagiellonian-PET Laboratory, Jagiellonian University , Krak\u00f3w , Poland","institution_ids":["https://openalex.org/I126596746"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5090813957"],"corresponding_institution_ids":["https://openalex.org/I126596746","https://openalex.org/I4210086947"],"apc_list":null,"apc_paid":null,"fwci":0.8948,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.73634677,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"17","issue":"4","first_page":"301","last_page":"309"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9905999898910522,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9894999861717224,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-delivery","display_name":"Drug delivery","score":0.8086366057395935},{"id":"https://openalex.org/keywords/biocompatibility","display_name":"Biocompatibility","score":0.785382866859436},{"id":"https://openalex.org/keywords/extracellular-vesicles","display_name":"Extracellular vesicles","score":0.7816579341888428},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5929363965988159},{"id":"https://openalex.org/keywords/positron-emission-tomography","display_name":"Positron emission tomography","score":0.5799132585525513},{"id":"https://openalex.org/keywords/extracellular-vesicle","display_name":"Extracellular vesicle","score":0.42485305666923523},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.37712952494621277},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.34103769063949585},{"id":"https://openalex.org/keywords/microvesicles","display_name":"Microvesicles","score":0.2831032872200012},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.16310551762580872},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.13064050674438477},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.11963805556297302},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11799246072769165},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.1156458854675293}],"concepts":[{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.8086366057395935},{"id":"https://openalex.org/C2777230088","wikidata":"https://www.wikidata.org/wiki/Q864426","display_name":"Biocompatibility","level":2,"score":0.785382866859436},{"id":"https://openalex.org/C2992929900","wikidata":"https://www.wikidata.org/wiki/Q21097485","display_name":"Extracellular vesicles","level":2,"score":0.7816579341888428},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5929363965988159},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.5799132585525513},{"id":"https://openalex.org/C2908689518","wikidata":"https://www.wikidata.org/wiki/Q21097485","display_name":"Extracellular vesicle","level":5,"score":0.42485305666923523},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37712952494621277},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.34103769063949585},{"id":"https://openalex.org/C20518536","wikidata":"https://www.wikidata.org/wiki/Q6840469","display_name":"Microvesicles","level":4,"score":0.2831032872200012},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16310551762580872},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.13064050674438477},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11963805556297302},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11799246072769165},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.1156458854675293},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1515/bams-2021-0183","is_oa":false,"landing_page_url":"https://doi.org/10.1515/bams-2021-0183","pdf_url":null,"source":{"id":"https://openalex.org/S2764861201","display_name":"Bio-Algorithms and Med-Systems","issn_l":"1895-9091","issn":["1895-9091","1896-530X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bio-Algorithms and Med-Systems","raw_type":"journal-article"},{"id":"pmh:oai:ruj.uj.edu.pl:item/289165","is_oa":true,"landing_page_url":"https://ruj.uj.edu.pl/xmlui/handle/item/289165","pdf_url":null,"source":{"id":"https://openalex.org/S4306401249","display_name":"Jagiellonian University Repository (Jagiellonian University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I126596746","host_organization_name":"Jagiellonian University","host_organization_lineage":["https://openalex.org/I126596746"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"artyku\u0142 w czasopi\u015bmie"}],"best_oa_location":{"id":"pmh:oai:ruj.uj.edu.pl:item/289165","is_oa":true,"landing_page_url":"https://ruj.uj.edu.pl/xmlui/handle/item/289165","pdf_url":null,"source":{"id":"https://openalex.org/S4306401249","display_name":"Jagiellonian University Repository (Jagiellonian University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I126596746","host_organization_name":"Jagiellonian University","host_organization_lineage":["https://openalex.org/I126596746"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"artyku\u0142 w czasopi\u015bmie"},"sustainable_development_goals":[{"score":0.7900000214576721,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":85,"referenced_works":["https://openalex.org/W94975780","https://openalex.org/W1518948065","https://openalex.org/W1543484487","https://openalex.org/W1545033903","https://openalex.org/W1674139320","https://openalex.org/W1972070926","https://openalex.org/W1973175384","https://openalex.org/W1973894250","https://openalex.org/W1980593265","https://openalex.org/W1980712639","https://openalex.org/W2000864558","https://openalex.org/W2005700555","https://openalex.org/W2010498435","https://openalex.org/W2017269547","https://openalex.org/W2026448131","https://openalex.org/W2037876980","https://openalex.org/W2040344708","https://openalex.org/W2062313115","https://openalex.org/W2062359734","https://openalex.org/W2070951546","https://openalex.org/W2086752790","https://openalex.org/W2111778115","https://openalex.org/W2122187912","https://openalex.org/W2134921841","https://openalex.org/W2170866255","https://openalex.org/W2255402501","https://openalex.org/W2281134225","https://openalex.org/W2334994929","https://openalex.org/W2471151834","https://openalex.org/W2471537403","https://openalex.org/W2550737778","https://openalex.org/W2552356858","https://openalex.org/W2561664203","https://openalex.org/W2706098188","https://openalex.org/W2765701791","https://openalex.org/W2767001807","https://openalex.org/W2770941870","https://openalex.org/W2771457674","https://openalex.org/W2786514708","https://openalex.org/W2787963369","https://openalex.org/W2806514836","https://openalex.org/W2810857568","https://openalex.org/W2813096576","https://openalex.org/W2893560612","https://openalex.org/W2903872251","https://openalex.org/W2905270996","https://openalex.org/W2909117814","https://openalex.org/W2909484970","https://openalex.org/W2912992980","https://openalex.org/W2920862005","https://openalex.org/W2939992495","https://openalex.org/W2951827335","https://openalex.org/W2975244376","https://openalex.org/W2976566869","https://openalex.org/W2996570510","https://openalex.org/W3019432882","https://openalex.org/W3020850248","https://openalex.org/W3030779614","https://openalex.org/W3044909776","https://openalex.org/W3046148594","https://openalex.org/W3048476253","https://openalex.org/W3081421293","https://openalex.org/W3093210051","https://openalex.org/W3095322863","https://openalex.org/W3099550905","https://openalex.org/W3100376982","https://openalex.org/W3109744624","https://openalex.org/W3118996078","https://openalex.org/W3127512504","https://openalex.org/W3133141774","https://openalex.org/W3147582525","https://openalex.org/W3164272096","https://openalex.org/W3165539291","https://openalex.org/W3170068038","https://openalex.org/W3178919463","https://openalex.org/W3184065957","https://openalex.org/W3184279022","https://openalex.org/W3200048715","https://openalex.org/W3202778286","https://openalex.org/W3207803940","https://openalex.org/W3212049551","https://openalex.org/W3212764783","https://openalex.org/W4200400228","https://openalex.org/W4231810863","https://openalex.org/W4247847065"],"related_works":["https://openalex.org/W2076500439","https://openalex.org/W4248868287","https://openalex.org/W4391232704","https://openalex.org/W4391036707","https://openalex.org/W4389489847","https://openalex.org/W4205183504","https://openalex.org/W4214502885","https://openalex.org/W3047759831","https://openalex.org/W4224434456","https://openalex.org/W3030780191"],"abstract_inverted_index":{"Abstract":[0],"Extracellular":[1],"vesicles":[2],"(EVs)":[3],"are":[4],"nano-":[5],"and":[6,16,25,55,73],"micro-sized":[7],"double-layered":[8],"membrane":[9],"entities":[10],"derived":[11],"from":[12],"most":[13],"cell":[14],"types":[15],"released":[17],"into":[18],"biological":[19],"fluids.":[20],"Biological":[21],"properties":[22],"(cell-uptake,":[23],"biocompatibility),":[24],"chemical":[26],"(composition,":[27],"structure)":[28],"or":[29],"physical":[30],"(size,":[31],"density)":[32],"characteristics":[33],"make":[34],"EVs":[35,50,70],"a":[36,77],"good":[37],"candidate":[38],"for":[39],"drug":[40],"delivery":[41],"systems":[42],"(DDS).":[43],"Recent":[44],"advances":[45],"in":[46,71,80],"the":[47],"field":[48],"of":[49,57,68],"(e.g.,":[51],"scaling-up":[52],"production,":[53],"purification)":[54],"developments":[56],"new":[58],"imaging":[59],"methods":[60],"(total-body":[61],"positron":[62],"emission":[63],"tomography":[64],"[PET])":[65],"revealed":[66],"benefits":[67],"radiolabeled":[69],"diagnostic":[72],"interventional":[74],"medicine":[75],"as":[76],"potential":[78],"DDs":[79],"theranostics.":[81]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}