{"id":"https://openalex.org/W2884734736","doi":"https://doi.org/10.1515/bams-2018-0015","title":"Brain stem modeling at a system level \u2013 chances and limitations","display_name":"Brain stem modeling at a system level \u2013 chances and limitations","publication_year":2018,"publication_date":"2018-06-01","ids":{"openalex":"https://openalex.org/W2884734736","doi":"https://doi.org/10.1515/bams-2018-0015","mag":"2884734736"},"language":"en","primary_location":{"id":"doi:10.1515/bams-2018-0015","is_oa":false,"landing_page_url":"https://doi.org/10.1515/bams-2018-0015","pdf_url":null,"source":{"id":"https://openalex.org/S2764861201","display_name":"Bio-Algorithms and Med-Systems","issn_l":"1895-9091","issn":["1895-9091","1896-530X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bio-Algorithms and Med-Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086266633","display_name":"Dariusz Miko\u0142ajewski","orcid":"https://orcid.org/0000-0003-4157-2796"},"institutions":[{"id":"https://openalex.org/I149592570","display_name":"Kazimierz Wielki University in Bydgoszcz","ror":"https://ror.org/018zpxs61","country_code":"PL","type":"education","lineage":["https://openalex.org/I149592570"]},{"id":"https://openalex.org/I3019271933","display_name":"Nicolaus Copernicus University","ror":"https://ror.org/0102mm775","country_code":"PL","type":"education","lineage":["https://openalex.org/I3019271933"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Dariusz Mikolajewski","raw_affiliation_strings":["Centre for Modern Interdisciplinary Technologies , Nicolaus Copernicus University \u2013 Neurocognitive Laboratory , Torun , Poland","Institute of Mechanics and Applied Computer Science, Kazimierz Wielki University , Bydgoszcz , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Modern Interdisciplinary Technologies , Nicolaus Copernicus University \u2013 Neurocognitive Laboratory , Torun , Poland","institution_ids":["https://openalex.org/I3019271933"]},{"raw_affiliation_string":"Institute of Mechanics and Applied Computer Science, Kazimierz Wielki University , Bydgoszcz , Poland","institution_ids":["https://openalex.org/I149592570"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081855156","display_name":"W\u0142odzis\u0142aw Duch","orcid":"https://orcid.org/0000-0001-7882-4729"},"institutions":[{"id":"https://openalex.org/I3019271933","display_name":"Nicolaus Copernicus University","ror":"https://ror.org/0102mm775","country_code":"PL","type":"education","lineage":["https://openalex.org/I3019271933"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"W\u0142odzis\u0142aw Duch","raw_affiliation_strings":["Centre for Modern Interdisciplinary Technologies , Nicolaus Copernicus University \u2013 Neurocognitive Laboratory , Torun , Poland","Department of Informatics, Faculty of Physics, Astronomy and Informatics , Nicolaus Copernicus University , Torun , Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Modern Interdisciplinary Technologies , Nicolaus Copernicus University \u2013 Neurocognitive Laboratory , Torun , Poland","institution_ids":["https://openalex.org/I3019271933"]},{"raw_affiliation_string":"Department of Informatics, Faculty of Physics, Astronomy and Informatics , Nicolaus Copernicus University , Torun , Poland","institution_ids":["https://openalex.org/I3019271933"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5086266633"],"corresponding_institution_ids":["https://openalex.org/I149592570","https://openalex.org/I3019271933"],"apc_list":null,"apc_paid":null,"fwci":0.2079,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.48199345,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"14","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9919999837875366,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.9883999824523926,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.7541642785072327},{"id":"https://openalex.org/keywords/neurorehabilitation","display_name":"Neurorehabilitation","score":0.6400049924850464},{"id":"https://openalex.org/keywords/computational-model","display_name":"Computational model","score":0.5937910079956055},{"id":"https://openalex.org/keywords/computational-neuroscience","display_name":"Computational neuroscience","score":0.5784593224525452},{"id":"https://openalex.org/keywords/stem-cell","display_name":"Stem cell","score":0.47689488530158997},{"id":"https://openalex.org/keywords/neurology","display_name":"Neurology","score":0.4540596008300781},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.41960686445236206},{"id":"https://openalex.org/keywords/cognitive-science","display_name":"Cognitive science","score":0.3913375735282898},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3715531826019287},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2641547918319702},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.16332599520683289},{"id":"https://openalex.org/keywords/rehabilitation","display_name":"Rehabilitation","score":0.14169567823410034}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7541642785072327},{"id":"https://openalex.org/C47177892","wikidata":"https://www.wikidata.org/wiki/Q3510101","display_name":"Neurorehabilitation","level":3,"score":0.6400049924850464},{"id":"https://openalex.org/C66024118","wikidata":"https://www.wikidata.org/wiki/Q1122506","display_name":"Computational model","level":2,"score":0.5937910079956055},{"id":"https://openalex.org/C15286952","wikidata":"https://www.wikidata.org/wiki/Q8037925","display_name":"Computational neuroscience","level":2,"score":0.5784593224525452},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.47689488530158997},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.4540596008300781},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.41960686445236206},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.3913375735282898},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3715531826019287},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2641547918319702},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.16332599520683289},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.14169567823410034},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1515/bams-2018-0015","is_oa":false,"landing_page_url":"https://doi.org/10.1515/bams-2018-0015","pdf_url":null,"source":{"id":"https://openalex.org/S2764861201","display_name":"Bio-Algorithms and Med-Systems","issn_l":"1895-9091","issn":["1895-9091","1896-530X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bio-Algorithms and Med-Systems","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/4","score":0.6600000262260437,"display_name":"Quality Education"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W72462972","https://openalex.org/W568454345","https://openalex.org/W1557947605","https://openalex.org/W1596839545","https://openalex.org/W1892724428","https://openalex.org/W1968184972","https://openalex.org/W1969288633","https://openalex.org/W1971167492","https://openalex.org/W1979388897","https://openalex.org/W1981577790","https://openalex.org/W1985869553","https://openalex.org/W2003862720","https://openalex.org/W2005254605","https://openalex.org/W2005912149","https://openalex.org/W2018870204","https://openalex.org/W2023362602","https://openalex.org/W2026468267","https://openalex.org/W2027763844","https://openalex.org/W2056205485","https://openalex.org/W2057889680","https://openalex.org/W2062178670","https://openalex.org/W2070201373","https://openalex.org/W2077930207","https://openalex.org/W2078098251","https://openalex.org/W2084458727","https://openalex.org/W2088101817","https://openalex.org/W2088977202","https://openalex.org/W2090457573","https://openalex.org/W2090515270","https://openalex.org/W2095596789","https://openalex.org/W2124865189","https://openalex.org/W2126757042","https://openalex.org/W2165096765","https://openalex.org/W2747235193","https://openalex.org/W4232952028","https://openalex.org/W4255229883"],"related_works":["https://openalex.org/W4252166826","https://openalex.org/W2887972576","https://openalex.org/W2324968893","https://openalex.org/W2340883203","https://openalex.org/W2062563783","https://openalex.org/W3105486044","https://openalex.org/W2586858905","https://openalex.org/W2064354742","https://openalex.org/W4289740581","https://openalex.org/W2949828687"],"abstract_inverted_index":{"Abstract":[0],"The":[1,103],"topic":[2],"of":[3,25,30,60,72,78,93,105,118,140,153],"brain":[4,21,50,95,120,142],"stem":[5,22,37,51,96,121,143],"computational":[6,94,119,147],"simulation":[7],"still":[8],"seems":[9,98],"understudied":[10],"in":[11,17,49,81,90,115],"contemporary":[12],"scientific":[13],"literature.":[14],"Current":[15],"advances":[16],"neuroscience":[18],"leave":[19],"the":[20,26,31,43,58,82,91,112,116,126,137,141],"as":[23],"one":[24],"least":[27],"known":[28],"parts":[29],"human":[32],"central":[33],"nervous":[34],"system.":[35],"Brain":[36],"lesions":[38],"are":[39,108],"particularly":[40],"damaging":[41],"to":[42,99,110,124,128],"most":[44],"important":[45,55],"physiological":[46],"functions.":[47],"Advances":[48],"modeling":[52],"may":[53,68,132],"influence":[54],"issues":[56],"within":[57],"core":[59,156],"neurology,":[61],"neurophysiology,":[62],"neurosurgery,":[63],"and":[64,74,76,123],"neurorehabilitation.":[65],"Direct":[66],"results":[67],"include":[69],"both":[70,109],"development":[71],"knowledge":[73],"optimization":[75],"objectivization":[77],"clinical":[79],"practice":[80],"aforementioned":[83],"medical":[84],"areas.":[85],"Despite":[86,135],"these":[87],"needs,":[88],"progress":[89],"area":[92,117],"models":[97,148],"be":[100,133],"too":[101],"slow.":[102],"aims":[104],"this":[106],"paper":[107],"recognize":[111],"strongest":[113],"limitations":[114],"simulations":[122],"assess":[125],"extent":[127],"which":[129],"current":[130],"opportunities":[131],"exploited.":[134],"limitations,":[136],"emerging":[138],"view":[139],"provided":[144],"by":[145],"its":[146],"enables":[149],"a":[150],"wide":[151],"repertoire":[152],"functions,":[154],"including":[155],"dynamic":[157],"behavior.":[158]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}