{"id":"https://openalex.org/W4396705599","doi":"https://doi.org/10.1515/auto-2023-0206","title":"A switching lung mechanics model for detection of expiratory flow limitation","display_name":"A switching lung mechanics model for detection of expiratory flow limitation","publication_year":2024,"publication_date":"2024-05-01","ids":{"openalex":"https://openalex.org/W4396705599","doi":"https://doi.org/10.1515/auto-2023-0206"},"language":"en","primary_location":{"id":"doi:10.1515/auto-2023-0206","is_oa":false,"landing_page_url":"https://doi.org/10.1515/auto-2023-0206","pdf_url":null,"source":{"id":"https://openalex.org/S4210170077","display_name":"at - Automatisierungstechnik","issn_l":"0178-2312","issn":["0178-2312","2196-677X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319967","host_organization_name":"R. Oldenbourg Verlag","host_organization_lineage":["https://openalex.org/P4310319967"],"host_organization_lineage_names":["R. Oldenbourg Verlag"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"at - Automatisierungstechnik","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031269872","display_name":"Carlotta Hennigs","orcid":"https://orcid.org/0000-0002-2227-8316"},"institutions":[{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Carlotta Hennigs","raw_affiliation_strings":["9191 Institute of Electrical Engineering in Medicine, Universit\u00e4t zu L\u00fcbeck , Luebeck , Germany"],"raw_orcid":"https://orcid.org/0000-0002-2227-8316","affiliations":[{"raw_affiliation_string":"9191 Institute of Electrical Engineering in Medicine, Universit\u00e4t zu L\u00fcbeck , Luebeck , Germany","institution_ids":["https://openalex.org/I9341345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001981594","display_name":"Franziska Bilda","orcid":"https://orcid.org/0000-0003-3230-1898"},"institutions":[{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Franziska Bilda","raw_affiliation_strings":["9191 Institute of Electrical Engineering in Medicine, Universit\u00e4t zu L\u00fcbeck , Luebeck , Germany"],"raw_orcid":"https://orcid.org/0000-0003-3230-1898","affiliations":[{"raw_affiliation_string":"9191 Institute of Electrical Engineering in Medicine, Universit\u00e4t zu L\u00fcbeck , Luebeck , Germany","institution_ids":["https://openalex.org/I9341345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003265327","display_name":"Jan Gra\u00dfhoff","orcid":"https://orcid.org/0000-0002-6528-0950"},"institutions":[{"id":"https://openalex.org/I4210130518","display_name":"Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering","ror":"https://ror.org/039c0bt50","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4210130518","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jan Gra\u00dfhoff","raw_affiliation_strings":["Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering , Luebeck , Germany"],"raw_orcid":"https://orcid.org/0000-0002-6528-0950","affiliations":[{"raw_affiliation_string":"Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering , Luebeck , Germany","institution_ids":["https://openalex.org/I4210130518"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043243321","display_name":"Stephan Walterspacher","orcid":"https://orcid.org/0000-0003-3061-1251"},"institutions":[{"id":"https://openalex.org/I155976169","display_name":"Witten/Herdecke University","ror":"https://ror.org/00yq55g44","country_code":"DE","type":"education","lineage":["https://openalex.org/I155976169"]},{"id":"https://openalex.org/I4210138844","display_name":"Klinikum Konstanz","ror":"https://ror.org/03z5ka349","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210138844"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stephan Walterspacher","raw_affiliation_strings":["Medical Clinic \u2013 Dept of Pneumology, Klinikum Konstanz, Germany and Faculty of Health/School of Medicine , Witten/Herdecke University , Witten , Germany"],"raw_orcid":"https://orcid.org/0000-0003-3061-1251","affiliations":[{"raw_affiliation_string":"Medical Clinic \u2013 Dept of Pneumology, Klinikum Konstanz, Germany and Faculty of Health/School of Medicine , Witten/Herdecke University , Witten , Germany","institution_ids":["https://openalex.org/I4210138844","https://openalex.org/I155976169"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011641162","display_name":"Philipp Rostalski","orcid":"https://orcid.org/0000-0003-0326-168X"},"institutions":[{"id":"https://openalex.org/I4210130518","display_name":"Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering","ror":"https://ror.org/039c0bt50","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4210130518","https://openalex.org/I4923324"]},{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Philipp Rostalski","raw_affiliation_strings":["9191 Institute of Electrical Engineering in Medicine, Universit\u00e4t zu L\u00fcbeck , Luebeck , Germany","Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering , Luebeck , Germany","Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering, Luebeck, Germany"],"raw_orcid":"https://orcid.org/0000-0003-0326-168X","affiliations":[{"raw_affiliation_string":"9191 Institute of Electrical Engineering in Medicine, Universit\u00e4t zu L\u00fcbeck , Luebeck , Germany","institution_ids":["https://openalex.org/I9341345"]},{"raw_affiliation_string":"Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering , Luebeck , Germany","institution_ids":["https://openalex.org/I4210130518"]},{"raw_affiliation_string":"Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering, Luebeck, Germany","institution_ids":["https://openalex.org/I4210130518"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5031269872"],"corresponding_institution_ids":["https://openalex.org/I9341345"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.1333931,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"72","issue":"5","first_page":"417","last_page":"428"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":0.9934999942779541,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/expiration","display_name":"Expiration","score":0.7075785398483276},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4883272349834442},{"id":"https://openalex.org/keywords/clinical-practice","display_name":"Clinical Practice","score":0.4349607229232788},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.29109853506088257},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.15410369634628296},{"id":"https://openalex.org/keywords/respiratory-system","display_name":"Respiratory system","score":0.11347529292106628}],"concepts":[{"id":"https://openalex.org/C2776164194","wikidata":"https://www.wikidata.org/wiki/Q2501440","display_name":"Expiration","level":3,"score":0.7075785398483276},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4883272349834442},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.4349607229232788},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29109853506088257},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15410369634628296},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.11347529292106628},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1515/auto-2023-0206","is_oa":false,"landing_page_url":"https://doi.org/10.1515/auto-2023-0206","pdf_url":null,"source":{"id":"https://openalex.org/S4210170077","display_name":"at - Automatisierungstechnik","issn_l":"0178-2312","issn":["0178-2312","2196-677X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319967","host_organization_name":"R. Oldenbourg Verlag","host_organization_lineage":["https://openalex.org/P4310319967"],"host_organization_lineage_names":["R. Oldenbourg Verlag"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"at - Automatisierungstechnik","raw_type":"journal-article"},{"id":"pmh:oai:publica.fraunhofer.de:publica/474197","is_oa":false,"landing_page_url":"https://publica.fraunhofer.de/handle/publica/474197","pdf_url":null,"source":{"id":"https://openalex.org/S4306400318","display_name":"Fraunhofer-Publica (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.44999998807907104,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1862464476","https://openalex.org/W1984822101","https://openalex.org/W1998764444","https://openalex.org/W2008932324","https://openalex.org/W2019453384","https://openalex.org/W2042688108","https://openalex.org/W2055053369","https://openalex.org/W2096290318","https://openalex.org/W2115258294","https://openalex.org/W2123758797","https://openalex.org/W2125078269","https://openalex.org/W2125761526","https://openalex.org/W2127951128","https://openalex.org/W2177222627","https://openalex.org/W2754596981","https://openalex.org/W2766492659","https://openalex.org/W2790682405","https://openalex.org/W2801979497","https://openalex.org/W2806026049","https://openalex.org/W2958760774","https://openalex.org/W3023978259","https://openalex.org/W3040358118","https://openalex.org/W3205425043","https://openalex.org/W4200211878","https://openalex.org/W4210499430","https://openalex.org/W4226460904","https://openalex.org/W4241391200","https://openalex.org/W4311694669"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2748952813","https://openalex.org/W2334334908","https://openalex.org/W2185059918","https://openalex.org/W2388729234","https://openalex.org/W1968959651","https://openalex.org/W2044460202","https://openalex.org/W1483562105","https://openalex.org/W2068155189","https://openalex.org/W2020946025"],"abstract_inverted_index":{"Abstract":[0],"Expiratory":[1],"flow":[2,25,73],"limitation":[3,74,85],"(EFL)":[4],"is":[5,21,31,53,117],"an":[6,122],"often":[7],"unrecognized":[8],"clinical":[9,64,128],"condition":[10],"with":[11,38],"a":[12,32,39,56,118],"multitude":[13],"of":[14,66,92,105,112,125,136],"negative":[15],"implications.":[16],"A":[17],"mathematical":[18],"EFL":[19,29,51,114,126],"model":[20,30,37,58],"proposed":[22],"to":[23,43,133],"detect":[24],"limitations":[26],"automatically.":[27],"The":[28,50],"switching":[33],"one-compartment":[34],"lung":[35],"mechanics":[36],"volume-dependent":[40],"airway":[41],"resistance":[42],"simulate":[44],"the":[45,71,83,93,101,110,113],"dynamic":[46],"behavior":[47],"during":[48],"expiration.":[49],"detection":[52,103,124],"based":[54],"on":[55,63,100],"breath-by-breath":[57],"parameter":[59],"identification":[60],"and":[61,81,130],"validated":[62],"data":[65],"mechanically":[67],"ventilated":[68],"patients.":[69],"In":[70],"severe":[72],"group":[75,86],"93.9":[76],"%":[77,80,88,91],"\u00b1":[78,89],"5":[79],"in":[82,127],"no":[84],"10.2":[87],"13.7":[90],"breaths":[94],"are":[95],"detected":[96],"as":[97],"EFL.":[98,137],"Based":[99],"high":[102],"rate":[104],"EFL,":[106],"these":[107],"results":[108],"support":[109],"usefulness":[111],"detection.":[115],"It":[116],"first":[119],"step":[120],"toward":[121],"automated":[123],"applications":[129],"may":[131],"help":[132],"reduce":[134],"underdiagnosis":[135]},"counts_by_year":[],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}