{"id":"https://openalex.org/W2782535620","doi":"https://doi.org/10.1504/ijdmb.2017.10010188","title":"Pattern recognition of chemical compounds using multiple dose-response curves","display_name":"Pattern recognition of chemical compounds using multiple dose-response curves","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2782535620","doi":"https://doi.org/10.1504/ijdmb.2017.10010188","mag":"2782535620"},"language":"en","primary_location":{"id":"doi:10.1504/ijdmb.2017.10010188","is_oa":false,"landing_page_url":"https://doi.org/10.1504/ijdmb.2017.10010188","pdf_url":null,"source":{"id":"https://openalex.org/S35771696","display_name":"International Journal of Data Mining and Bioinformatics","issn_l":"1748-5673","issn":["1748-5673","1748-5681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310317825","host_organization_name":"Inderscience Publishers","host_organization_lineage":["https://openalex.org/P4310317825"],"host_organization_lineage_names":["Inderscience Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Data Mining and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110963270","display_name":"Xiaobo Zou","orcid":null},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaobo Zou","raw_affiliation_strings":["School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China"],"affiliations":[{"raw_affiliation_string":"School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China","institution_ids":["https://openalex.org/I115592961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062951448","display_name":"Tianhong Pan","orcid":"https://orcid.org/0000-0002-0993-3937"},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tianhong Pan","raw_affiliation_strings":["School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China","institution_ids":["https://openalex.org/I115592961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027584014","display_name":"Kaili Xu","orcid":"https://orcid.org/0000-0001-5054-1241"},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kaili Xu","raw_affiliation_strings":["School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China","institution_ids":["https://openalex.org/I115592961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100369731","display_name":"Shan Chen","orcid":"https://orcid.org/0000-0001-7613-3940"},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shan Chen","raw_affiliation_strings":["School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China","institution_ids":["https://openalex.org/I115592961"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100441171","display_name":"Jiao Chen","orcid":"https://orcid.org/0000-0003-2367-4369"},"institutions":[{"id":"https://openalex.org/I4210108723","display_name":"Changzhou Institute of Technology","ror":"https://ror.org/020mrfq61","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210108723"]},{"id":"https://openalex.org/I4210153482","display_name":"Changzhou University","ror":"https://ror.org/04ymgwq66","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210153482"]},{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]},{"id":"https://openalex.org/I4210144214","display_name":"Jiangsu University of Technology","ror":"https://ror.org/04jabhf80","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210144214"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiao Chen","raw_affiliation_strings":["School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China; School of Electronics and Electrical Engineering, Changzhou College of Information Technology, Changzhou, Jiangsu 213164, China","School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China","School of Electronics and Electrical Engineering, Changzhou College of Information Technology, Changzhou, Jiangsu 213164, China"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China; School of Electronics and Electrical Engineering, Changzhou College of Information Technology, Changzhou, Jiangsu 213164, China","institution_ids":["https://openalex.org/I4210144214","https://openalex.org/I115592961","https://openalex.org/I4210153482"]},{"raw_affiliation_string":"School of Electrical and Information Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China","institution_ids":["https://openalex.org/I115592961"]},{"raw_affiliation_string":"School of Electronics and Electrical Engineering, Changzhou College of Information Technology, Changzhou, Jiangsu 213164, China","institution_ids":["https://openalex.org/I4210108723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5110963270"],"corresponding_institution_ids":["https://openalex.org/I115592961"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.1903925,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"19","issue":"2","first_page":"97","last_page":"97"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11667","display_name":"Advanced Chemical Sensor Technologies","score":0.9850999712944031,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11667","display_name":"Advanced Chemical Sensor Technologies","score":0.9850999712944031,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.9599000215530396,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.9569000005722046,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.649633526802063},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.6213620901107788},{"id":"https://openalex.org/keywords/collinearity","display_name":"Collinearity","score":0.5732431411743164},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5684118270874023},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"Cytotoxicity","score":0.4667176604270935},{"id":"https://openalex.org/keywords/singular-value-decomposition","display_name":"Singular value decomposition","score":0.46527808904647827},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.42783623933792114},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.40752243995666504},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3829079866409302},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.30146467685699463},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.27859020233154297},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2515680193901062},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.09746187925338745}],"concepts":[{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.649633526802063},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.6213620901107788},{"id":"https://openalex.org/C106192678","wikidata":"https://www.wikidata.org/wiki/Q1419761","display_name":"Collinearity","level":2,"score":0.5732431411743164},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5684118270874023},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.4667176604270935},{"id":"https://openalex.org/C22789450","wikidata":"https://www.wikidata.org/wiki/Q420904","display_name":"Singular value decomposition","level":2,"score":0.46527808904647827},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.42783623933792114},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.40752243995666504},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3829079866409302},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30146467685699463},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.27859020233154297},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2515680193901062},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09746187925338745},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1504/ijdmb.2017.10010188","is_oa":false,"landing_page_url":"https://doi.org/10.1504/ijdmb.2017.10010188","pdf_url":null,"source":{"id":"https://openalex.org/S35771696","display_name":"International Journal of Data Mining and Bioinformatics","issn_l":"1748-5673","issn":["1748-5673","1748-5681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310317825","host_organization_name":"Inderscience Publishers","host_organization_lineage":["https://openalex.org/P4310317825"],"host_organization_lineage_names":["Inderscience Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Data Mining and Bioinformatics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2159670039","https://openalex.org/W4226120311","https://openalex.org/W3016530894","https://openalex.org/W2058928070","https://openalex.org/W4233429336","https://openalex.org/W4235291650","https://openalex.org/W3196914014","https://openalex.org/W4256422528","https://openalex.org/W2140731556","https://openalex.org/W1647640974"],"abstract_inverted_index":{"To":[0],"determine":[1],"distinct":[2],"chemical":[3,141],"properties":[4],"characterised":[5],"by":[6,46],"Mechanism":[7],"of":[8,33,71,80,100],"Action":[9],"(MoA),":[10],"a":[11,52,62,122],"pattern":[12],"recognition":[13,142],"algorithm":[14],"using":[15],"multiple":[16],"dose-response":[17,63,86],"curves":[18],"is":[19,65,94,114],"developed":[20],"in":[21,42,60,102],"this":[22],"paper.":[23],"By":[24],"monitoring":[25],"the":[26,57,69,72,78,85,89,98,103,118,124,144],"dynamic":[27],"time-dependent":[28],"cellular":[29,145],"response":[30],"profiles":[31],"(TCRPs)":[32],"living":[34],"cells":[35],"via":[36],"Real":[37],"Time":[38],"Cellular":[39],"Analyser,":[40],"changes":[41],"cell":[43],"number":[44],"caused":[45],"different":[47],"MoAs":[48],"are":[49,82,127],"recorded":[50],"as":[51],"time":[53],"series.":[54],"Based":[55],"on":[56],"toxic-effect":[58],"observed":[59],"TCRPs,":[61],"curve":[64],"established,":[66],"which":[67,76],"reflect":[68,77],"cytotoxicity":[70],"tested":[73,125],"chemicals.":[74],"Features,":[75],"levels":[79],"cytotoxicity,":[81],"extracted":[83,104],"from":[84],"curves.":[87],"And":[88],"singular":[90],"value":[91],"decomposition":[92],"(SVD)":[93],"taken":[95],"to":[96,116],"reduce":[97],"effect":[99],"collinearity":[101],"features.":[105,120],"A":[106],"k-means":[107],"clustering":[108],"method":[109,134],"with":[110],"deterministic":[111],"initial":[112],"centres":[113],"employed":[115],"classify":[117],"compressed":[119],"As":[121],"result,":[123],"chemicals":[126],"classified":[128],"into":[129],"several":[130],"groups.":[131],"The":[132],"proposed":[133],"enables":[135],"relatively":[136],"high":[137],"throughput":[138],"screening":[139],"for":[140],"at":[143],"level.":[146]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}