{"id":"https://openalex.org/W2146392361","doi":"https://doi.org/10.1504/ijdmb.2013.056616","title":"A robust hidden semi-Markov model with application to aCGH data processing","display_name":"A robust hidden semi-Markov model with application to aCGH data processing","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2146392361","doi":"https://doi.org/10.1504/ijdmb.2013.056616","mag":"2146392361","pmid":"https://pubmed.ncbi.nlm.nih.gov/24400520"},"language":"en","primary_location":{"id":"doi:10.1504/ijdmb.2013.056616","is_oa":false,"landing_page_url":"https://doi.org/10.1504/ijdmb.2013.056616","pdf_url":null,"source":{"id":"https://openalex.org/S35771696","display_name":"International Journal of Data Mining and Bioinformatics","issn_l":"1748-5673","issn":["1748-5673","1748-5681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310317825","host_organization_name":"Inderscience Publishers","host_organization_lineage":["https://openalex.org/P4310317825"],"host_organization_lineage_names":["Inderscience Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Data Mining and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050542674","display_name":"Jiarui Ding","orcid":"https://orcid.org/0000-0003-3670-7764"},"institutions":[{"id":"https://openalex.org/I1287378978","display_name":"University of British Columbia Hospital","ror":"https://ror.org/00frst980","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1287378978","https://openalex.org/I141074466","https://openalex.org/I141074466","https://openalex.org/I141945490","https://openalex.org/I2799475292"]},{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jiarui Ding","raw_affiliation_strings":["Department of Computer Science, University of British Columbia, Vancouver, Canada. jiaruid@cs.ubc.ca","Department of Computer Science, University of British Columbia; Department of Molecular Biology, BC Cancer Agency, Vancouver, BC, V5T 4E6, Canada#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of British Columbia, Vancouver, Canada. jiaruid@cs.ubc.ca","institution_ids":["https://openalex.org/I1287378978","https://openalex.org/I141945490"]},{"raw_affiliation_string":"Department of Computer Science, University of British Columbia; Department of Molecular Biology, BC Cancer Agency, Vancouver, BC, V5T 4E6, Canada#TAB#","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033441782","display_name":"Sohrab P. Shah","orcid":"https://orcid.org/0000-0001-6402-523X"},"institutions":[{"id":"https://openalex.org/I1289530486","display_name":"BC Cancer Agency","ror":"https://ror.org/03sfybe47","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1289530486"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Sohrab Shah","raw_affiliation_strings":["Department of Computer Science, University of British Columbia, Vancouver, Canada","Department of Computer Science, University of British Columbia; Department of Molecular Biology, BC Cancer Agency; Department of Pathology, University of British Columbia, Vancouver, BC, V5T 4E6, ...#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of British Columbia, Vancouver, Canada","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"Department of Computer Science, University of British Columbia; Department of Molecular Biology, BC Cancer Agency; Department of Pathology, University of British Columbia, Vancouver, BC, V5T 4E6, ...#TAB#","institution_ids":["https://openalex.org/I1289530486","https://openalex.org/I141945490"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2752,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.60223714,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"8","issue":"4","first_page":"427","last_page":"427"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11901","display_name":"Bayesian Methods and Mixture Models","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/outlier","display_name":"Outlier","score":0.7983849048614502},{"id":"https://openalex.org/keywords/hidden-markov-model","display_name":"Hidden Markov model","score":0.7056238055229187},{"id":"https://openalex.org/keywords/markov-model","display_name":"Markov model","score":0.6390561461448669},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5968201160430908},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.5820563435554504},{"id":"https://openalex.org/keywords/glioblastoma","display_name":"Glioblastoma","score":0.5392483472824097},{"id":"https://openalex.org/keywords/comparative-genomic-hybridization","display_name":"Comparative genomic hybridization","score":0.5281971096992493},{"id":"https://openalex.org/keywords/markov-chain","display_name":"Markov chain","score":0.4858545958995819},{"id":"https://openalex.org/keywords/reliability","display_name":"Reliability (semiconductor)","score":0.4673236906528473},{"id":"https://openalex.org/keywords/data-driven","display_name":"Data-driven","score":0.4290667474269867},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4206019341945648},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.38363635540008545},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.2546251714229584},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1473749577999115},{"id":"https://openalex.org/keywords/power","display_name":"Power (physics)","score":0.12873366475105286}],"concepts":[{"id":"https://openalex.org/C79337645","wikidata":"https://www.wikidata.org/wiki/Q779824","display_name":"Outlier","level":2,"score":0.7983849048614502},{"id":"https://openalex.org/C23224414","wikidata":"https://www.wikidata.org/wiki/Q176769","display_name":"Hidden Markov model","level":2,"score":0.7056238055229187},{"id":"https://openalex.org/C163836022","wikidata":"https://www.wikidata.org/wiki/Q6771326","display_name":"Markov model","level":3,"score":0.6390561461448669},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5968201160430908},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.5820563435554504},{"id":"https://openalex.org/C2776194525","wikidata":"https://www.wikidata.org/wiki/Q282142","display_name":"Glioblastoma","level":2,"score":0.5392483472824097},{"id":"https://openalex.org/C124942203","wikidata":"https://www.wikidata.org/wiki/Q656638","display_name":"Comparative genomic hybridization","level":4,"score":0.5281971096992493},{"id":"https://openalex.org/C98763669","wikidata":"https://www.wikidata.org/wiki/Q176645","display_name":"Markov chain","level":2,"score":0.4858545958995819},{"id":"https://openalex.org/C43214815","wikidata":"https://www.wikidata.org/wiki/Q7310987","display_name":"Reliability (semiconductor)","level":3,"score":0.4673236906528473},{"id":"https://openalex.org/C2780440489","wikidata":"https://www.wikidata.org/wiki/Q5227278","display_name":"Data-driven","level":2,"score":0.4290667474269867},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4206019341945648},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.38363635540008545},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.2546251714229584},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1473749577999115},{"id":"https://openalex.org/C163258240","wikidata":"https://www.wikidata.org/wiki/Q25342","display_name":"Power (physics)","level":2,"score":0.12873366475105286},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D001330","descriptor_name":"Electronic Data Processing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001330","descriptor_name":"Electronic Data Processing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001330","descriptor_name":"Electronic Data Processing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002877","descriptor_name":"Chromosomes, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002877","descriptor_name":"Chromosomes, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002877","descriptor_name":"Chromosomes, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008390","descriptor_name":"Markov Chains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055028","descriptor_name":"Comparative Genomic Hybridization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055028","descriptor_name":"Comparative Genomic Hybridization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055028","descriptor_name":"Comparative Genomic Hybridization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1504/ijdmb.2013.056616","is_oa":false,"landing_page_url":"https://doi.org/10.1504/ijdmb.2013.056616","pdf_url":null,"source":{"id":"https://openalex.org/S35771696","display_name":"International Journal of Data Mining and Bioinformatics","issn_l":"1748-5673","issn":["1748-5673","1748-5681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310317825","host_organization_name":"Inderscience Publishers","host_organization_lineage":["https://openalex.org/P4310317825"],"host_organization_lineage_names":["Inderscience Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Data Mining and Bioinformatics","raw_type":"journal-article"},{"id":"pmid:24400520","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24400520","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of data mining and bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323180","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1481143593","https://openalex.org/W1486632395","https://openalex.org/W1503398984","https://openalex.org/W1506806321","https://openalex.org/W1559899545","https://openalex.org/W1663973292","https://openalex.org/W1855901833","https://openalex.org/W1989844119","https://openalex.org/W2005028383","https://openalex.org/W2076618452","https://openalex.org/W2078130187","https://openalex.org/W2113574907","https://openalex.org/W2123452832","https://openalex.org/W2127710810","https://openalex.org/W2133174470","https://openalex.org/W2134012290","https://openalex.org/W2137971377","https://openalex.org/W2140170007","https://openalex.org/W2170510631"],"related_works":["https://openalex.org/W1510894296","https://openalex.org/W2134386692","https://openalex.org/W2082284720","https://openalex.org/W2194396582","https://openalex.org/W2116722627","https://openalex.org/W2537260108","https://openalex.org/W2379938888","https://openalex.org/W4233405330","https://openalex.org/W2792905593","https://openalex.org/W1977445474"],"abstract_inverted_index":{"Hidden":[0],"semi-Markov":[1,34],"models":[2,40],"are":[3],"effective":[4],"at":[5],"modelling":[6],"sequences":[7],"with":[8,36],"succession":[9],"of":[10,76],"homogenous":[11],"zones":[12],"by":[13],"choosing":[14],"appropriate":[15],"state":[16],"duration":[17],"distributions.":[18,44],"To":[19],"compensate":[20],"for":[21],"model":[22,35,51],"mis-specification":[23],"and":[24,69],"provide":[25],"protection":[26],"against":[27],"outliers,":[28],"we":[29],"design":[30],"a":[31],"robust":[32],"hidden":[33],"Student's":[37],"t":[38],"mixture":[39],"as":[41],"the":[42,61,65,74,77],"emission":[43],"The":[45],"proposed":[46],"approach":[47],"is":[48],"used":[49],"to":[50],"array":[52],"based":[53],"comparative":[54],"genomic":[55],"hybridization":[56],"data.":[57],"Experiments":[58],"conducted":[59],"on":[60],"benchmark":[62],"data":[63,72],"from":[64],"Coriell":[66],"cell":[67],"lines,":[68],"glioblastoma":[70],"multiforme":[71],"illustrate":[73],"reliability":[75],"technique.":[78]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":2}],"updated_date":"2026-07-29T09:40:50.615796","created_date":"2025-10-10T00:00:00"}