{"id":"https://openalex.org/W4253257378","doi":"https://doi.org/10.1504/ijbra.2017.10002824","title":"Annotation transfer by homology among closely related genomes helps to identify protein function in Plasmodium species","display_name":"Annotation transfer by homology among closely related genomes helps to identify protein function in Plasmodium species","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W4253257378","doi":"https://doi.org/10.1504/ijbra.2017.10002824"},"language":"en","primary_location":{"id":"doi:10.1504/ijbra.2017.10002824","is_oa":false,"landing_page_url":"https://doi.org/10.1504/ijbra.2017.10002824","pdf_url":null,"source":{"id":"https://openalex.org/S207086575","display_name":"International Journal of Bioinformatics Research and Applications","issn_l":"1744-5485","issn":["1744-5485","1744-5493"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310317825","host_organization_name":"Inderscience Publishers","host_organization_lineage":["https://openalex.org/P4310317825"],"host_organization_lineage_names":["Inderscience Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Bioinformatics Research and Applications","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Devaraj Raghul Rajan","orcid":null},"institutions":[{"id":"https://openalex.org/I3132429795","display_name":"Adigrat University","ror":"https://ror.org/0034mdn74","country_code":"ET","type":"education","lineage":["https://openalex.org/I3132429795"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Devaraj Raghul Rajan","raw_affiliation_strings":["Department of Biology, College of Natural and Computational Sciences, Adigrat University, Adigrat 25150, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, College of Natural and Computational Sciences, Adigrat University, Adigrat 25150, Ethiopia","institution_ids":["https://openalex.org/I3132429795"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084589905","display_name":"Bathrachalam Chandramohan","orcid":"https://orcid.org/0000-0002-3464-7553"},"institutions":[{"id":"https://openalex.org/I4210139093","display_name":"SciGenom Research Foundation","ror":"https://ror.org/04gstme54","country_code":"IN","type":"nonprofit","lineage":["https://openalex.org/I4210139093"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Bathrachalam Chandramohan","raw_affiliation_strings":["SciGenom Research Foundation, #55, First Floor, 1st Kamaraj Avenue, Kasturibai Nagar, Adyar, Chennai 600020, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SciGenom Research Foundation, #55, First Floor, 1st Kamaraj Avenue, Kasturibai Nagar, Adyar, Chennai 600020, India","institution_ids":["https://openalex.org/I4210139093"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.25957428,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":"1","first_page":"22","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9520999789237976,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.7772690057754517},{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.662446141242981},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.6623235940933228},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5932889580726624},{"id":"https://openalex.org/keywords/genome-project","display_name":"Genome project","score":0.5903677940368652},{"id":"https://openalex.org/keywords/homology","display_name":"Homology (biology)","score":0.5041707754135132},{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.492678701877594},{"id":"https://openalex.org/keywords/hypothetical-protein","display_name":"Hypothetical protein","score":0.487765371799469},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.48415881395339966},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.4751158356666565},{"id":"https://openalex.org/keywords/gene-ontology","display_name":"Gene ontology","score":0.47082215547561646},{"id":"https://openalex.org/keywords/plasmodium-knowlesi","display_name":"Plasmodium knowlesi","score":0.4591789245605469},{"id":"https://openalex.org/keywords/gene-annotation","display_name":"Gene Annotation","score":0.443208783864975},{"id":"https://openalex.org/keywords/malaria","display_name":"Malaria","score":0.30083024501800537},{"id":"https://openalex.org/keywords/plasmodium-vivax","display_name":"Plasmodium vivax","score":0.28838393092155457}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7772690057754517},{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.662446141242981},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6623235940933228},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5932889580726624},{"id":"https://openalex.org/C89566754","wikidata":"https://www.wikidata.org/wiki/Q2273828","display_name":"Genome project","level":4,"score":0.5903677940368652},{"id":"https://openalex.org/C165525559","wikidata":"https://www.wikidata.org/wiki/Q224180","display_name":"Homology (biology)","level":3,"score":0.5041707754135132},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.492678701877594},{"id":"https://openalex.org/C129075420","wikidata":"https://www.wikidata.org/wiki/Q10855009","display_name":"Hypothetical protein","level":3,"score":0.487765371799469},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.48415881395339966},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4751158356666565},{"id":"https://openalex.org/C2987395477","wikidata":"https://www.wikidata.org/wiki/Q135085","display_name":"Gene ontology","level":4,"score":0.47082215547561646},{"id":"https://openalex.org/C2780559468","wikidata":"https://www.wikidata.org/wiki/Q241594","display_name":"Plasmodium knowlesi","level":5,"score":0.4591789245605469},{"id":"https://openalex.org/C2908923196","wikidata":"https://www.wikidata.org/wiki/Q5205742","display_name":"Gene Annotation","level":4,"score":0.443208783864975},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.30083024501800537},{"id":"https://openalex.org/C2779997623","wikidata":"https://www.wikidata.org/wiki/Q311376","display_name":"Plasmodium vivax","level":4,"score":0.28838393092155457},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1504/ijbra.2017.10002824","is_oa":false,"landing_page_url":"https://doi.org/10.1504/ijbra.2017.10002824","pdf_url":null,"source":{"id":"https://openalex.org/S207086575","display_name":"International Journal of Bioinformatics Research and Applications","issn_l":"1744-5485","issn":["1744-5485","1744-5493"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310317825","host_organization_name":"Inderscience Publishers","host_organization_lineage":["https://openalex.org/P4310317825"],"host_organization_lineage_names":["Inderscience Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Bioinformatics Research and Applications","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6399999856948853,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2164883151","https://openalex.org/W2162782320","https://openalex.org/W2112871141","https://openalex.org/W2059565715","https://openalex.org/W2967275775","https://openalex.org/W2279845149","https://openalex.org/W2078942911","https://openalex.org/W2294108133","https://openalex.org/W4280623106","https://openalex.org/W2073064803"],"abstract_inverted_index":{"Malaria":[0],"is":[1],"a":[2],"major":[3],"killer":[4],"disease":[5],"causing":[6],"heavy":[7],"loss":[8],"in":[9,22,41,62,71,160],"terms":[10],"of":[11,18,28,94,154,163],"life":[12],"and":[13,48,156,166],"medical":[14],"expenditure.":[15],"The":[16,122],"genome":[17],"Plasmodium":[19],"falciparum":[20,40],"sequenced":[21],"2002":[23],"but":[24],"more":[25],"than":[26],"60%":[27],"its":[29],"meaning":[30],"still":[31],"remains":[32],"unknown.":[33],"We":[34,57],"compared":[35],"protein":[36,101],"sequences":[37,44,117],"from":[38,55],"P.":[39,46,49],"the":[42,72,77,89,115,152,161],"genomic":[43],"with":[45,68,106,111,119],"vivax":[47],"knowlesi":[50],"through":[51],"standalone":[52],"blast":[53],"tool":[54],"NCBI.":[56],"found":[58],"many":[59],"proteins":[60,70,110,127,130,144],"annotated":[61,84,99],"one":[63],"species":[64],"sharing":[65],"high":[66],"similarity":[67],"unannotated":[69],"other/s":[73],"species.":[74],"Based":[75],"on":[76,151],"'annotation":[78],"transfer":[79],"by":[80],"homology'":[81],"method":[82,98],"we":[83],"715":[85],"hypothetical":[86],"proteins.":[87],"By":[88],"latest":[90],"information":[91],"available":[92],"as":[93,145],"1st":[95],"September":[96],"our":[97],"343":[100],"sequences.":[102],"Gene":[103],"Ontology":[104],"annotation":[105],"BLAST2GO":[107],"revealed":[108],"128":[109],"Enzyme":[112],"Codes":[113],"among":[114],"561":[116],"mapped":[118],"GO":[120],"terms.":[121],"kognitor":[123],"results":[124],"showed":[125],"542":[126],"similar":[128],"to":[129,132,141],"belonging":[131],"various":[133],"KOG":[134],"categories.":[135],"More":[136],"attention":[137],"should":[138],"be":[139],"paid":[140],"these":[142],"'hypothetical'":[143],"they":[146],"can":[147],"reveal":[148],"unknown":[149],"insights":[150],"biology":[153],"organisms":[155],"have":[157],"an":[158],"impact":[159],"field":[162],"drug":[164],"discovery":[165],"medicine.":[167]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}