{"id":"https://openalex.org/W2077103371","doi":"https://doi.org/10.1504/ijbra.2006.009762","title":"Protein sub-cellular localisation prediction by analysis of short-range residue correlations","display_name":"Protein sub-cellular localisation prediction by analysis of short-range residue correlations","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W2077103371","doi":"https://doi.org/10.1504/ijbra.2006.009762","mag":"2077103371","pmid":"https://pubmed.ncbi.nlm.nih.gov/18048156"},"language":"en","primary_location":{"id":"doi:10.1504/ijbra.2006.009762","is_oa":false,"landing_page_url":"https://doi.org/10.1504/ijbra.2006.009762","pdf_url":null,"source":{"id":"https://openalex.org/S207086575","display_name":"International Journal of Bioinformatics Research and Applications","issn_l":"1744-5485","issn":["1744-5485","1744-5493"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310317825","host_organization_name":"Inderscience Publishers","host_organization_lineage":["https://openalex.org/P4310317825"],"host_organization_lineage_names":["Inderscience Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Bioinformatics Research and Applications","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100607719","display_name":"Jian Guo","orcid":"https://orcid.org/0000-0002-3722-6578"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jian Guo","raw_affiliation_strings":["Laboratory of Statistical Computing and Bioinformatics, Department of Mathematical Sciences, Tsinghua University, Beijing, PR China. guojian99@tsinghua.org.cn","Laboratory of Statistical Computing and Bioinformatics, Department of Mathematical Sciences, Tsinghua University, Beijing 100084, PR China.#TAB#"],"affiliations":[{"raw_affiliation_string":"Laboratory of Statistical Computing and Bioinformatics, Department of Mathematical Sciences, Tsinghua University, Beijing, PR China. guojian99@tsinghua.org.cn","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Laboratory of Statistical Computing and Bioinformatics, Department of Mathematical Sciences, Tsinghua University, Beijing 100084, PR China.#TAB#","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100944926","display_name":"Yuanlie Lin","orcid":null},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuanlie Lin","raw_affiliation_strings":["","Laboratory of Statistical Computing and Bioinformatics, Department of Mathematical Sciences, Tsinghua University, Beijing 100084, PR China.#TAB#"],"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Laboratory of Statistical Computing and Bioinformatics, Department of Mathematical Sciences, Tsinghua University, Beijing 100084, PR China.#TAB#","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101577441","display_name":"Zhirong Sun","orcid":"https://orcid.org/0000-0003-0703-0221"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhirong Sun","raw_affiliation_strings":["","MOE Key Lab of Bioinformatics, State Key Lab of Biomembrane and Membrane Biotechnology, Institute of Bioinformatics, Department of Biological Sciences and Biotechnology, Tsinghua University, Beiji "],"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"MOE Key Lab of Bioinformatics, State Key Lab of Biomembrane and Membrane Biotechnology, Institute of Bioinformatics, Department of Biological Sciences and Biotechnology, Tsinghua University, Beiji ","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100607719"],"corresponding_institution_ids":["https://openalex.org/I99065089"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10847758,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":"2","first_page":"105","last_page":"105"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.5742226839065552},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5129567980766296},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5113484263420105},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.43813714385032654},{"id":"https://openalex.org/keywords/range","display_name":"Range (aeronautics)","score":0.42444974184036255},{"id":"https://openalex.org/keywords/protein-methods","display_name":"Protein methods","score":0.41868090629577637},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.39284124970436096},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.383327454328537},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3488422632217407},{"id":"https://openalex.org/keywords/sequence-analysis","display_name":"Sequence analysis","score":0.27315858006477356},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.19585078954696655},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1029936671257019},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08022117614746094}],"concepts":[{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.5742226839065552},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5129567980766296},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5113484263420105},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.43813714385032654},{"id":"https://openalex.org/C204323151","wikidata":"https://www.wikidata.org/wiki/Q905424","display_name":"Range (aeronautics)","level":2,"score":0.42444974184036255},{"id":"https://openalex.org/C111364199","wikidata":"https://www.wikidata.org/wiki/Q2915896","display_name":"Protein methods","level":4,"score":0.41868090629577637},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.39284124970436096},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.383327454328537},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3488422632217407},{"id":"https://openalex.org/C61053724","wikidata":"https://www.wikidata.org/wiki/Q1154615","display_name":"Sequence analysis","level":3,"score":0.27315858006477356},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19585078954696655},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1029936671257019},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08022117614746094},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001695","descriptor_name":"Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001695","descriptor_name":"Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001695","descriptor_name":"Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1504/ijbra.2006.009762","is_oa":false,"landing_page_url":"https://doi.org/10.1504/ijbra.2006.009762","pdf_url":null,"source":{"id":"https://openalex.org/S207086575","display_name":"International Journal of Bioinformatics Research and Applications","issn_l":"1744-5485","issn":["1744-5485","1744-5493"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310317825","host_organization_name":"Inderscience Publishers","host_organization_lineage":["https://openalex.org/P4310317825"],"host_organization_lineage_names":["Inderscience Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Bioinformatics Research and Applications","raw_type":"journal-article"},{"id":"pmid:18048156","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18048156","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of bioinformatics research and applications","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320335774","display_name":"Key Technologies Research and Development Program","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1491250132","https://openalex.org/W1985582731","https://openalex.org/W1993711987","https://openalex.org/W2020194549","https://openalex.org/W2025131366","https://openalex.org/W2070547667","https://openalex.org/W2082605863","https://openalex.org/W2085022192","https://openalex.org/W2096059361","https://openalex.org/W2100851422","https://openalex.org/W2119452210","https://openalex.org/W2148603752","https://openalex.org/W2148622452","https://openalex.org/W2150773524","https://openalex.org/W2152458080","https://openalex.org/W2156909104","https://openalex.org/W2158120166","https://openalex.org/W2160979370","https://openalex.org/W2169043568"],"related_works":["https://openalex.org/W2090763504","https://openalex.org/W148178222","https://openalex.org/W2104657898","https://openalex.org/W1948992892","https://openalex.org/W1886884218","https://openalex.org/W1910826599","https://openalex.org/W1980100242","https://openalex.org/W2530420969","https://openalex.org/W2051187167","https://openalex.org/W4315815996"],"abstract_inverted_index":{"Sub-cellular":[0],"localisation":[1,25],"performs":[2],"an":[3],"important":[4],"role":[5],"in":[6,71,88],"genome":[7],"analysis.":[8],"This":[9,28],"paper":[10],"describes":[11],"a":[12,17,64],"new":[13,29,65],"residue-couple":[14],"model":[15,82],"using":[16],"support":[18],"vector":[19],"machine":[20],"to":[21],"predict":[22],"the":[23,35,75,81,89],"sub-cellular":[24,73],"of":[26],"proteins.":[27],"approach":[30],"provides":[31],"better":[32],"predictions":[33],"than":[34],"existing":[36],"methods.":[37],"The":[38],"total":[39,76],"prediction":[40],"accuracies":[41],"on":[42],"Reinhardt":[43],"and":[44,53],"Hubbard's":[45],"dataset":[46,66],"reach":[47],"92.0%":[48],"for":[49,55],"prokaryotic":[50],"protein":[51,57],"sequences":[52,58],"86.9%":[54],"eukaryotic":[56],"with":[59,67],"fivefold":[60],"cross":[61],"validation.":[62],"For":[63],"8304":[68],"proteins":[69],"located":[70],"eight":[72],"locations,":[74],"accuracy":[77],"achieves":[78],"88.9%.":[79],"Meanwhile,":[80],"shows":[83],"robust":[84],"against":[85],"N-terminal":[86],"errors":[87],"sequences.":[90]},"counts_by_year":[],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}