{"id":"https://openalex.org/W3033855543","doi":"https://doi.org/10.1371/journal.pcbi.1007182","title":"Epidemiological consequences of enduring strain-specific immunity requiring repeated episodes of infection","display_name":"Epidemiological consequences of enduring strain-specific immunity requiring repeated episodes of infection","publication_year":2020,"publication_date":"2020-06-05","ids":{"openalex":"https://openalex.org/W3033855543","doi":"https://doi.org/10.1371/journal.pcbi.1007182","mag":"3033855543","pmid":"https://pubmed.ncbi.nlm.nih.gov/32502148"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1007182","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007182","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1007182&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1007182&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107384769","display_name":"Rebecca H. Chisholm","orcid":"https://orcid.org/0000-0002-7830-793X"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I196829312","display_name":"La Trobe University","ror":"https://ror.org/01rxfrp27","country_code":"AU","type":"education","lineage":["https://openalex.org/I196829312"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Rebecca H. Chisholm","raw_affiliation_strings":["Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia","Department of Mathematics and Statistics, La Trobe University, Melbourne, Victoria, Australia"],"raw_orcid":"https://orcid.org/0000-0002-7830-793X","affiliations":[{"raw_affiliation_string":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Department of Mathematics and Statistics, La Trobe University, Melbourne, Victoria, Australia","institution_ids":["https://openalex.org/I196829312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038780061","display_name":"Nikki Sonenberg","orcid":"https://orcid.org/0000-0002-2133-9842"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Nikki Sonenberg","raw_affiliation_strings":["Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia"],"raw_orcid":"https://orcid.org/0000-0002-2133-9842","affiliations":[{"raw_affiliation_string":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057151261","display_name":"Jake A. Lacey","orcid":"https://orcid.org/0000-0002-6492-6983"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jake A. Lacey","raw_affiliation_strings":["Doherty Department University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia"],"raw_orcid":"https://orcid.org/0000-0002-6492-6983","affiliations":[{"raw_affiliation_string":"Doherty Department University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006513180","display_name":"Malcolm McDonald","orcid":"https://orcid.org/0000-0002-7225-8671"},"institutions":[{"id":"https://openalex.org/I2801053747","display_name":"Australian Institute of Tropical Health and Medicine","ror":"https://ror.org/03dsbfb14","country_code":"AU","type":"facility","lineage":["https://openalex.org/I2801053747"]},{"id":"https://openalex.org/I86467917","display_name":"James Cook University","ror":"https://ror.org/04gsp2c11","country_code":"AU","type":"education","lineage":["https://openalex.org/I86467917"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Malcolm I. McDonald","raw_affiliation_strings":["Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Queensland, Australia"],"raw_orcid":"https://orcid.org/0000-0002-7225-8671","affiliations":[{"raw_affiliation_string":"Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Queensland, Australia","institution_ids":["https://openalex.org/I2801053747","https://openalex.org/I86467917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052305148","display_name":"Manisha Pandey","orcid":"https://orcid.org/0000-0002-4151-699X"},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Manisha Pandey","raw_affiliation_strings":["Institute for Glycomics, Gold Coast Campus, Griffith University, Brisbane, Queensland, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Glycomics, Gold Coast Campus, Griffith University, Brisbane, Queensland, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074629918","display_name":"Mark R. Davies","orcid":"https://orcid.org/0000-0001-6141-5179"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Mark R. Davies","raw_affiliation_strings":["Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia"],"raw_orcid":"https://orcid.org/0000-0001-6141-5179","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074189743","display_name":"Steven Y. C. Tong","orcid":"https://orcid.org/0000-0002-1368-8356"},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"funder","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I29894533","display_name":"Charles Darwin University","ror":"https://ror.org/048zcaj52","country_code":"AU","type":"education","lineage":["https://openalex.org/I29894533"]},{"id":"https://openalex.org/I4210085939","display_name":"Menzies School of Health Research","ror":"https://ror.org/006mbby82","country_code":"AU","type":"funder","lineage":["https://openalex.org/I4210085939"]},{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Steven Y. C. Tong","raw_affiliation_strings":["Doherty Department University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia","Menzies School of Health Research, Charles Darwin University, Darwin, Australia","Victorian Infectious Diseases Service, The Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia"],"raw_orcid":"https://orcid.org/0000-0002-1368-8356","affiliations":[{"raw_affiliation_string":"Doherty Department University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I165779595"]},{"raw_affiliation_string":"Menzies School of Health Research, Charles Darwin University, Darwin, Australia","institution_ids":["https://openalex.org/I29894533","https://openalex.org/I4210085939"]},{"raw_affiliation_string":"Victorian Infectious Diseases Service, The Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I1320473756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000523306","display_name":"Jodie McVernon","orcid":"https://orcid.org/0000-0001-9774-1961"},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"funder","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210088630","display_name":"Victorian Infectious Diseases Reference Laboratory","ror":"https://ror.org/005ynf375","country_code":"AU","type":"facility","lineage":["https://openalex.org/I4210088630"]},{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jodie McVernon","raw_affiliation_strings":["Victorian Infectious Diseases Reference Laboratory Epidemiology Unit at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Victoria, Australia"],"raw_orcid":"https://orcid.org/0000-0001-9774-1961","affiliations":[{"raw_affiliation_string":"Victorian Infectious Diseases Reference Laboratory Epidemiology Unit at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Victoria, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I165779595","https://openalex.org/I1320473756","https://openalex.org/I4210088630"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061048717","display_name":"Nicholas Geard","orcid":"https://orcid.org/0000-0003-0069-2281"},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"funder","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210088630","display_name":"Victorian Infectious Diseases Reference Laboratory","ror":"https://ror.org/005ynf375","country_code":"AU","type":"facility","lineage":["https://openalex.org/I4210088630"]},{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Nicholas Geard","raw_affiliation_strings":["School of Computing and Information Systems, Melbourne School of Engineering, The University of Melbourne, Melbourne, Victoria, Australia","Victorian Infectious Diseases Reference Laboratory Epidemiology Unit at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Victoria, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computing and Information Systems, Melbourne School of Engineering, The University of Melbourne, Melbourne, Victoria, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Victorian Infectious Diseases Reference Laboratory Epidemiology Unit at the Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Victoria, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I165779595","https://openalex.org/I1320473756","https://openalex.org/I4210088630"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5061048717"],"corresponding_institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210088630","https://openalex.org/I4210105123"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":1.0818,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.7947935,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"16","issue":"6","first_page":"e1007182","last_page":"e1007182"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11153","display_name":"Streptococcal Infections and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11153","display_name":"Streptococcal Infections and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.9883999824523926,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11961","display_name":"Neonatal and Maternal Infections","score":0.9681000113487244,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immunity","display_name":"Immunity","score":0.8322765827178955},{"id":"https://openalex.org/keywords/transmission","display_name":"Transmission (telecommunications)","score":0.6305522918701172},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.624361515045166},{"id":"https://openalex.org/keywords/epidemiology","display_name":"Epidemiology","score":0.590591311454773},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.5222381353378296},{"id":"https://openalex.org/keywords/strain","display_name":"Strain (injury)","score":0.5180578231811523},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.47787776589393616},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.40301239490509033},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.3407133221626282},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.11641767621040344}],"concepts":[{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.8322765827178955},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.6305522918701172},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.624361515045166},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.590591311454773},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5222381353378296},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.5180578231811523},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47787776589393616},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40301239490509033},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.3407133221626282},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11641767621040344},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011157","descriptor_name":"Population Dynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011157","descriptor_name":"Population Dynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011157","descriptor_name":"Population Dynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D012871","descriptor_name":"Skin Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D013297","descriptor_name":"Streptococcus pyogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013297","descriptor_name":"Streptococcus pyogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013297","descriptor_name":"Streptococcus pyogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D022541","descriptor_name":"Streptococcal Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022541","descriptor_name":"Streptococcal Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022541","descriptor_name":"Streptococcal Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044382","descriptor_name":"Population Groups","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044382","descriptor_name":"Population Groups","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044382","descriptor_name":"Population Groups","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050936","descriptor_name":"Basic Reproduction Number","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050936","descriptor_name":"Basic Reproduction Number","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050936","descriptor_name":"Basic Reproduction Number","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pcbi.1007182","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007182","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1007182&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:32502148","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32502148","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:jupiter.its.unimelb.edu.au:11343/241938","is_oa":true,"landing_page_url":"http://hdl.handle.net/11343/241938","pdf_url":"http://hdl.handle.net/11343/241938","source":{"id":"https://openalex.org/S4377196259","display_name":"Minerva Access (University of Melbourne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I165779595","host_organization_name":"The University of Melbourne","host_organization_lineage":["https://openalex.org/I165779595"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:research-repository.griffith.edu.au:10072/403688","is_oa":true,"landing_page_url":"http://hdl.handle.net/10072/403688","pdf_url":"http://hdl.handle.net/10072/403688","source":{"id":"https://openalex.org/S4306402548","display_name":"Griffith Research Online (Griffith University, Queensland, Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I11701301","host_organization_name":"Griffith University","host_organization_lineage":["https://openalex.org/I11701301"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal article"},{"id":"pmh:oai:doaj.org/article:8b9605c21e7b415087c1af9647af247c","is_oa":true,"landing_page_url":"https://doaj.org/article/8b9605c21e7b415087c1af9647af247c","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 16, Iss 6, p e1007182 (2020)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7299408","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7299408","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1007182","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1007182","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1007182&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8100000023841858,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1684245248","display_name":null,"funder_award_id":"APP1098319","funder_id":"https://openalex.org/F4320334705","funder_display_name":"National Health and Medical Research Council"},{"id":"https://openalex.org/G3853569357","display_name":null,"funder_award_id":"APP1058804","funder_id":"https://openalex.org/F4320334705","funder_display_name":"National Health and Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3033855543.pdf","grobid_xml":"https://content.openalex.org/works/W3033855543.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W1714437857","https://openalex.org/W1771974095","https://openalex.org/W1945949349","https://openalex.org/W1966485460","https://openalex.org/W1966602629","https://openalex.org/W1966875214","https://openalex.org/W1971707987","https://openalex.org/W1972948875","https://openalex.org/W1974918617","https://openalex.org/W1979766462","https://openalex.org/W1980220877","https://openalex.org/W1993302922","https://openalex.org/W1993507524","https://openalex.org/W1999399962","https://openalex.org/W2001488223","https://openalex.org/W2013293972","https://openalex.org/W2016808064","https://openalex.org/W2024413275","https://openalex.org/W2050684973","https://openalex.org/W2077184748","https://openalex.org/W2079466795","https://openalex.org/W2096108215","https://openalex.org/W2098785332","https://openalex.org/W2100884140","https://openalex.org/W2110379129","https://openalex.org/W2131765138","https://openalex.org/W2132813334","https://openalex.org/W2134376445","https://openalex.org/W2135497680","https://openalex.org/W2140652623","https://openalex.org/W2143930289","https://openalex.org/W2144428918","https://openalex.org/W2149759387","https://openalex.org/W2150562212","https://openalex.org/W2151229862","https://openalex.org/W2155605543","https://openalex.org/W2167591918","https://openalex.org/W2168460262","https://openalex.org/W2168919909","https://openalex.org/W2169536686","https://openalex.org/W2169958686","https://openalex.org/W2171225993","https://openalex.org/W2171780167","https://openalex.org/W2289775080","https://openalex.org/W2483178925","https://openalex.org/W2565216971","https://openalex.org/W2620571768","https://openalex.org/W2626327057","https://openalex.org/W2746455801","https://openalex.org/W2749972521","https://openalex.org/W2763692854","https://openalex.org/W2790313592","https://openalex.org/W2947571152"],"related_works":["https://openalex.org/W599478544","https://openalex.org/W1576711507","https://openalex.org/W647896512","https://openalex.org/W3121757313","https://openalex.org/W562084794","https://openalex.org/W4231462739","https://openalex.org/W167390939","https://openalex.org/W4385505472","https://openalex.org/W2065902429","https://openalex.org/W2613570068"],"abstract_inverted_index":{"Group":[0],"A":[1,42],"Streptococcus":[2],"(GAS)":[3],"skin":[4,58,284],"infections":[5,30,59,108,263],"are":[6,16],"caused":[7],"by":[8,60],"a":[9,35,76,114,169,181],"diverse":[10],"array":[11],"of":[12,24,70,82,92,100,180,193,227,240],"strain":[13,64,112,144],"types":[14],"and":[15,53,143,146,268],"highly":[17],"prevalent":[18],"in":[19,27,39,84,186,229,231],"disadvantaged":[20],"populations.":[21,85],"The":[22],"role":[23],"strain-specific":[25,52,102,183,235,257],"immunity":[26,55,73,83,103,206,236,258],"preventing":[28],"GAS":[29,44,63,93,163,218,228,247,283],"is":[31,253],"poorly":[32],"understood,":[33],"representing":[34],"critical":[36],"knowledge":[37],"gap":[38],"vaccine":[40,185,211,219],"development.":[41],"recent":[43],"murine":[45,122],"challenge":[46],"study":[47],"showed":[48],"evidence":[49],"that":[50,214,245],"sterilising":[51],"enduring":[54,72,101,205,256],"required":[56],"two":[57,107],"the":[61,80,97,110,177,199,215,225,265,278],"same":[62,111,266],"within":[65,113],"three":[66],"weeks.":[67,209],"This":[68],"mechanism":[69],"developing":[71,104,204],"may":[74,220],"be":[75],"significant":[77],"impediment":[78],"to":[79,95,124,134,137,276,282],"accumulation":[81],"We":[86,174],"used":[87],"an":[88],"agent-based":[89],"mathematical":[90],"model":[91,190],"transmission":[94,194],"investigate":[96],"epidemiological":[98],"consequences":[99],"only":[105],"after":[106],"with":[109,161,171,196,255,264],"specified":[115],"interval.":[116],"Accounting":[117],"for":[118,203,272],"uncertainty":[119],"when":[120,198],"correlating":[121],"timeframes":[123],"humans,":[125],"we":[126],"varied":[127],"this":[128,187],"maximum":[129,152,200],"inter-infection":[130,153,201],"interval":[131,154,202],"from":[132,166,249],"3":[133],"420":[135],"weeks":[136],"assess":[138],"its":[139],"impact":[140,179,223],"on":[141,224,261],"prevalence":[142,226],"diversity,":[145],"considered":[147],"additional":[148,270],"scenarios":[149],"where":[150],"no":[151],"was":[155,207],"specified.":[156],"Model":[157],"outputs":[158],"were":[159],"compared":[160],"longitudinal":[162],"surveillance":[164],"observations":[165,197],"northern":[167,232],"Australia,":[168],"region":[170],"endemic":[172,251],"infection.":[173,241,285],"also":[175],"assessed":[176],"likely":[178],"targeted":[182],"multivalent":[184,217],"context.":[188],"Our":[189,210,242],"produced":[191],"patterns":[192],"consistent":[195,254],"19":[208],"analysis":[212],"suggests":[213],"leading":[216],"have":[221],"limited":[222],"populations":[230],"Australia":[233],"if":[234],"requires":[237],"repeated":[238,262],"episodes":[239],"results":[243],"suggest":[244],"observed":[246],"epidemiology":[248],"disease":[250],"settings":[252],"being":[259],"dependent":[260],"strain,":[267],"provide":[269],"motivation":[271],"relevant":[273],"human":[274,279],"studies":[275],"confirm":[277],"immune":[280],"response":[281]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}