{"id":"https://openalex.org/W4413571425","doi":"https://doi.org/10.1371/journal.pcbi.1013374","title":"Integrated pan-cancer analysis of RNA binding protein HuR investigates its biomarker potential in prognosis, immunotherapy, and drug sensitivity","display_name":"Integrated pan-cancer analysis of RNA binding protein HuR investigates its biomarker potential in prognosis, immunotherapy, and drug sensitivity","publication_year":2025,"publication_date":"2025-08-25","ids":{"openalex":"https://openalex.org/W4413571425","doi":"https://doi.org/10.1371/journal.pcbi.1013374","pmid":"https://pubmed.ncbi.nlm.nih.gov/40853971"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1013374","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1013374","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1013374&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1013374&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108664496","display_name":"Jian Peng","orcid":"https://orcid.org/0009-0009-6780-4330"},"institutions":[{"id":"https://openalex.org/I4210147601","display_name":"Anhui Provincial Children's Hospital","ror":"https://ror.org/04je70584","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210147601"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jian Peng","raw_affiliation_strings":["Anhui Institute of Pediatric Research, Anhui Provincial Children's Hospital, Hefei, Anhui, China"],"affiliations":[{"raw_affiliation_string":"Anhui Institute of Pediatric Research, Anhui Provincial Children's Hospital, Hefei, Anhui, China","institution_ids":["https://openalex.org/I4210147601"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103875491","display_name":"Jichuan Quan","orcid":null},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jichuan Quan","raw_affiliation_strings":["Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China"],"affiliations":[{"raw_affiliation_string":"Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102020016","display_name":"Xiaoru Wang","orcid":"https://orcid.org/0000-0002-6150-7046"},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210133678","display_name":"Second Hospital of Shanxi Medical University","ror":"https://ror.org/03tn5kh37","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210133678"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoru Wang","raw_affiliation_strings":["Department of Critical Care Medicine, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China"],"affiliations":[{"raw_affiliation_string":"Department of Critical Care Medicine, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China","institution_ids":["https://openalex.org/I4210133678","https://openalex.org/I17721919"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5102020016","https://openalex.org/A5103875491","https://openalex.org/A5108664496"],"corresponding_institution_ids":["https://openalex.org/I17721919","https://openalex.org/I200296433","https://openalex.org/I4210133678","https://openalex.org/I4210147601"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.1934895,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"21","issue":"8","first_page":"e1013374","last_page":"e1013374"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.6469831466674805},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"Carcinogenesis","score":0.6344608068466187},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"Tumor microenvironment","score":0.613975465297699},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"Immunotherapy","score":0.6110882759094238},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.5727012753486633},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.5663719773292542},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.5649827718734741},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.48778825998306274},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"Cancer immunotherapy","score":0.4859112799167633},{"id":"https://openalex.org/keywords/malignancy","display_name":"Malignancy","score":0.44719386100769043},{"id":"https://openalex.org/keywords/immune-checkpoint","display_name":"Immune checkpoint","score":0.4160436689853668},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.34556323289871216},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.32703351974487305},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.07373377680778503}],"concepts":[{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.6469831466674805},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.6344608068466187},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.613975465297699},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.6110882759094238},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5727012753486633},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5663719773292542},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5649827718734741},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48778825998306274},{"id":"https://openalex.org/C2780674031","wikidata":"https://www.wikidata.org/wiki/Q2012719","display_name":"Cancer immunotherapy","level":4,"score":0.4859112799167633},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.44719386100769043},{"id":"https://openalex.org/C2780851360","wikidata":"https://www.wikidata.org/wiki/Q21686041","display_name":"Immune checkpoint","level":4,"score":0.4160436689853668},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.34556323289871216},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32703351974487305},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07373377680778503}],"mesh":[{"descriptor_ui":"D000067780","descriptor_name":"ELAV-Like Protein 1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000067780","descriptor_name":"ELAV-Like Protein 1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000067780","descriptor_name":"ELAV-Like Protein 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000067780","descriptor_name":"ELAV-Like Protein 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pcbi.1013374","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1013374","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1013374&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:40853971","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40853971","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:doaj.org/article:d655d4ed66454344a51252db94ed75c8","is_oa":true,"landing_page_url":"https://doaj.org/article/d655d4ed66454344a51252db94ed75c8","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 21, Iss 8 (2025)","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:e6249f7fca954b7683017c610eedd225","is_oa":true,"landing_page_url":"https://doaj.org/article/e6249f7fca954b7683017c610eedd225","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 21, Iss 8, p e1013374 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:11185566","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12377624","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1013374","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1013374","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1013374&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2089738447","display_name":null,"funder_award_id":"2022060","funder_id":"https://openalex.org/F4320317788","funder_display_name":"Health Commission of Shanxi Province"}],"funders":[{"id":"https://openalex.org/F4320317788","display_name":"Health Commission of Shanxi Province","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4413571425.pdf","grobid_xml":"https://content.openalex.org/works/W4413571425.grobid-xml"},"referenced_works_count":91,"referenced_works":["https://openalex.org/W1810028515","https://openalex.org/W2006617902","https://openalex.org/W2012034410","https://openalex.org/W2012942544","https://openalex.org/W2018838463","https://openalex.org/W2116130818","https://openalex.org/W2129849942","https://openalex.org/W2130430382","https://openalex.org/W2156205933","https://openalex.org/W2158485828","https://openalex.org/W2159707944","https://openalex.org/W2320793935","https://openalex.org/W2343838012","https://openalex.org/W2472500434","https://openalex.org/W2533508881","https://openalex.org/W2606669462","https://openalex.org/W2735598703","https://openalex.org/W2784351052","https://openalex.org/W2785329615","https://openalex.org/W2790893070","https://openalex.org/W2791403577","https://openalex.org/W2886005007","https://openalex.org/W2917612467","https://openalex.org/W2944670664","https://openalex.org/W2944727022","https://openalex.org/W2952391626","https://openalex.org/W2960027376","https://openalex.org/W2966710588","https://openalex.org/W3001475835","https://openalex.org/W3002398598","https://openalex.org/W3005086862","https://openalex.org/W3014677172","https://openalex.org/W3016985249","https://openalex.org/W3028304854","https://openalex.org/W3037315173","https://openalex.org/W3041157841","https://openalex.org/W3043489078","https://openalex.org/W3095376508","https://openalex.org/W3095431398","https://openalex.org/W3096112873","https://openalex.org/W3106930452","https://openalex.org/W3112918056","https://openalex.org/W3127493387","https://openalex.org/W3129551551","https://openalex.org/W3133859624","https://openalex.org/W3134431817","https://openalex.org/W3134553072","https://openalex.org/W3135313491","https://openalex.org/W3135330935","https://openalex.org/W3183874515","https://openalex.org/W3215777951","https://openalex.org/W4205990577","https://openalex.org/W4206839115","https://openalex.org/W4210412040","https://openalex.org/W4213237318","https://openalex.org/W4214860682","https://openalex.org/W4220860233","https://openalex.org/W4220913311","https://openalex.org/W4224136788","https://openalex.org/W4282002358","https://openalex.org/W4283721521","https://openalex.org/W4285891580","https://openalex.org/W4294930289","https://openalex.org/W4307245992","https://openalex.org/W4309890087","https://openalex.org/W4360816385","https://openalex.org/W4361204468","https://openalex.org/W4362703906","https://openalex.org/W4362704966","https://openalex.org/W4366133861","https://openalex.org/W4366261673","https://openalex.org/W4376615254","https://openalex.org/W4382777458","https://openalex.org/W4385969420","https://openalex.org/W4386554129","https://openalex.org/W4389452677","https://openalex.org/W4389936246","https://openalex.org/W4390825567","https://openalex.org/W4391565041","https://openalex.org/W4391671392","https://openalex.org/W4392202253","https://openalex.org/W4393935405","https://openalex.org/W4393935425","https://openalex.org/W4394768100","https://openalex.org/W4397036883","https://openalex.org/W4399521654","https://openalex.org/W4399607918","https://openalex.org/W4399639186","https://openalex.org/W4400318135","https://openalex.org/W4406431707","https://openalex.org/W4410472833"],"related_works":["https://openalex.org/W4200022043","https://openalex.org/W2112727616","https://openalex.org/W2884525857","https://openalex.org/W4410973507","https://openalex.org/W4322720888","https://openalex.org/W4296613612","https://openalex.org/W3111580887","https://openalex.org/W3049036915","https://openalex.org/W2902626376","https://openalex.org/W4313343001"],"abstract_inverted_index":{"Our":[0],"pan-cancer":[1],"analysis":[2],"establishes":[3],"HuR":[4,43],"as":[5,14],"a":[6,15],"consistently":[7],"upregulated":[8],"oncogenic":[9],"driver":[10],"across":[11],"malignancies,":[12],"functioning":[13],"potential":[16],"universal":[17],"biomarker":[18],"for":[19,38],"prognosis":[20],"and":[21,31,46],"diagnosis.":[22],"Its":[23],"critical":[24],"roles":[25],"in":[26],"modulating":[27],"the":[28],"immune":[29],"response":[30],"predicting":[32],"therapeutic":[33],"sensitivity":[34],"highlight":[35],"its":[36],"importance":[37],"personalized":[39],"cancer":[40],"treatment":[41],"strategies.":[42],"orchestrates":[44],"tumorigenesis":[45],"malignant":[47],"progression":[48],"by":[49],"integrally":[50],"regulating":[51],"vital":[52],"cellular":[53],"processes.":[54]},"counts_by_year":[],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}