{"id":"https://openalex.org/W4403172805","doi":"https://doi.org/10.1371/journal.pcbi.1012470","title":"A flexible generative algorithm for growing in silico placentas","display_name":"A flexible generative algorithm for growing in silico placentas","publication_year":2024,"publication_date":"2024-10-07","ids":{"openalex":"https://openalex.org/W4403172805","doi":"https://doi.org/10.1371/journal.pcbi.1012470","pmid":"https://pubmed.ncbi.nlm.nih.gov/39374295"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1012470","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1012470","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1371/journal.pcbi.1012470","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043105159","display_name":"Diana Oliveira","orcid":"https://orcid.org/0000-0002-8151-1333"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Diana C. de Oliveira","raw_affiliation_strings":["Department of Mechanical Engineering, University College London, London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107803236","display_name":"Hani Cheikh Sleiman","orcid":null},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Hani Cheikh Sleiman","raw_affiliation_strings":["Department of Mechanical Engineering, University College London, London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064000469","display_name":"Kelly Payette","orcid":null},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Kelly Payette","raw_affiliation_strings":["Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom","Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053114506","display_name":"Jana Hutter","orcid":"https://orcid.org/0000-0003-3476-3500"},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210088053","display_name":"Universit\u00e4tsklinikum Erlangen","ror":"https://ror.org/0030f2a11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088053"]}],"countries":["DE","GB"],"is_corresponding":true,"raw_author_name":"Jana Hutter","raw_affiliation_strings":["Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom","Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom","Smart Imaging Lab, Radiological Institute, University Hospital Erlangen, Erlangen, Germany"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Smart Imaging Lab, Radiological Institute, University Hospital Erlangen, Erlangen, Germany","institution_ids":["https://openalex.org/I4210088053"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091553785","display_name":"Lisa Story","orcid":"https://orcid.org/0000-0001-9328-9592"},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Lisa Story","raw_affiliation_strings":["Department of Women and Children's Health, School of Life Course Sciences, King's College London, London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Department of Women and Children's Health, School of Life Course Sciences, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085446806","display_name":"Joseph V. Hajnal","orcid":"https://orcid.org/0000-0002-2690-5495"},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Joseph V. Hajnal","raw_affiliation_strings":["Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom","Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033449704","display_name":"Daniel C. Alexander","orcid":"https://orcid.org/0000-0003-2439-350X"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Daniel C. Alexander","raw_affiliation_strings":["Centre for Medical Image Computing and Department of Computer Science, University College London, London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing and Department of Computer Science, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016183478","display_name":"Rebecca J. Shipley","orcid":"https://orcid.org/0000-0002-2818-6228"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Rebecca J. Shipley","raw_affiliation_strings":["Department of Mechanical Engineering, University College London, London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047882326","display_name":"Paddy J. Slator","orcid":"https://orcid.org/0000-0001-6967-989X"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I79510175","display_name":"Cardiff University","ror":"https://ror.org/03kk7td41","country_code":"GB","type":"education","lineage":["https://openalex.org/I79510175"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Paddy J. Slator","raw_affiliation_strings":["Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff, United Kingdom","Centre for Medical Image Computing and Department of Computer Science, University College London, London, United Kingdom","School of Computer Science and Informatics, Cardiff University, Cardiff, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff, United Kingdom","institution_ids":["https://openalex.org/I79510175"]},{"raw_affiliation_string":"Centre for Medical Image Computing and Department of Computer Science, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"School of Computer Science and Informatics, Cardiff University, Cardiff, United Kingdom","institution_ids":["https://openalex.org/I79510175"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5016183478","https://openalex.org/A5033449704","https://openalex.org/A5043105159","https://openalex.org/A5047882326","https://openalex.org/A5053114506","https://openalex.org/A5064000469","https://openalex.org/A5085446806","https://openalex.org/A5091553785","https://openalex.org/A5107803236"],"corresponding_institution_ids":["https://openalex.org/I183935753","https://openalex.org/I4210088053","https://openalex.org/I45129253","https://openalex.org/I79510175"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":1.1389,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.80310378,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"20","issue":"10","first_page":"e1012470","last_page":"e1012470"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11732","display_name":"Assisted Reproductive Technology and Twin Pregnancy","score":0.967199981212616,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.9010999798774719,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.6005608439445496},{"id":"https://openalex.org/keywords/placenta","display_name":"Placenta","score":0.5906157493591309},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5283989310264587},{"id":"https://openalex.org/keywords/branching","display_name":"Branching (polymer chemistry)","score":0.5198381543159485},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4427063763141632},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4016862213611603},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3885197043418884},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.3617594838142395},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.35710960626602173},{"id":"https://openalex.org/keywords/fetus","display_name":"Fetus","score":0.3146258592605591},{"id":"https://openalex.org/keywords/pregnancy","display_name":"Pregnancy","score":0.16296392679214478},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1417267620563507},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.13713160157203674},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.09250175952911377}],"concepts":[{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.6005608439445496},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.5906157493591309},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5283989310264587},{"id":"https://openalex.org/C206175624","wikidata":"https://www.wikidata.org/wiki/Q595731","display_name":"Branching (polymer chemistry)","level":2,"score":0.5198381543159485},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4427063763141632},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4016862213611603},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3885197043418884},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3617594838142395},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35710960626602173},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.3146258592605591},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.16296392679214478},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1417267620563507},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13713160157203674},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.09250175952911377},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":8,"locations":[{"id":"doi:10.1371/journal.pcbi.1012470","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1012470","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:39374295","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39374295","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10213554","is_oa":true,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10213554/","pdf_url":"https://discovery.ucl.ac.uk/10213554/1/Cheikh%20Sleiman_A_flexible_generative_algorithm_for_growing_in_sil.pdf","source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLOS Computational Biology , 20  (10)    , Article e1012470. (2024)","raw_type":"Article"},{"id":"pmh:oai:https://orca.cardiff.ac.uk:172661","is_oa":true,"landing_page_url":null,"pdf_url":"https://orca.cardiff.ac.uk/id/eprint/172661/1/journal.pcbi.1012470.pdf","source":{"id":"https://openalex.org/S4306401195","display_name":"ORCA Online Research @Cardiff (Cardiff University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79510175","host_organization_name":"Cardiff University","host_organization_lineage":["https://openalex.org/I79510175"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},{"id":"pmh:oai:open.fau.de:openfau/37948","is_oa":true,"landing_page_url":"https://open.fau.de/handle/openfau/37948","pdf_url":"https://open.fau.de/bitstreams/ce919949-d118-4d8d-815e-953eb8cac3ed/download","source":{"id":"https://openalex.org/S7407055110","display_name":"OPUS FAU - Online publication system of Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11486434","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11486434","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11486434/pdf/pcbi.1012470.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:RePEc:plo:pcbi00:1012470","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1012470","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:c71b972d1ac54adc8c8520f97bb512d9","is_oa":true,"landing_page_url":"https://doaj.org/article/c71b972d1ac54adc8c8520f97bb512d9","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 20, Iss 10, p e1012470 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1012470","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1012470","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7300000190734863,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G3295751497","display_name":"Oncological Engineering - A new concept in the treatment of bone metastases","funder_award_id":"EP/W007096/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G3499316743","display_name":"Assessing Placental Structure and Function by Unified Fluid Mechanical Modelling and in-vivo MRI","funder_award_id":"EP/V034537/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G3634600890","display_name":null,"funder_award_id":"EP/W007096/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G4215281196","display_name":null,"funder_award_id":"WT203148/Z/16/Z","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G4854867997","display_name":null,"funder_award_id":"Core funding","funder_id":"https://openalex.org/F4320335827","funder_display_name":"UCLH Biomedical Research Centre"},{"id":"https://openalex.org/G5296857752","display_name":null,"funder_award_id":"203148/Z/16/Z","funder_id":"https://openalex.org/F4320337314","funder_display_name":"Centre For Medical Engineering, King\u2019s College London"},{"id":"https://openalex.org/G5561172208","display_name":null,"funder_award_id":"WT203148/Z/16/Z","funder_id":"https://openalex.org/F4320337314","funder_display_name":"Centre For Medical Engineering, King\u2019s College London"},{"id":"https://openalex.org/G5611281780","display_name":null,"funder_award_id":"Core funding","funder_id":"https://openalex.org/F6625209195","funder_display_name":"Wellcome Leap"},{"id":"https://openalex.org/G5917232323","display_name":null,"funder_award_id":"WT203148/Z/16/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G6027190877","display_name":null,"funder_award_id":"MR/T018119/","funder_id":"https://openalex.org/F4320314731","funder_display_name":"UK Research and Innovation"},{"id":"https://openalex.org/G6203525002","display_name":null,"funder_award_id":"C44767/A29458","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G6537435729","display_name":null,"funder_award_id":"Heisenberg","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G6806397390","display_name":null,"funder_award_id":"EP/V034537/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G7452433591","display_name":null,"funder_award_id":"502024488","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G7752306322","display_name":null,"funder_award_id":"EP/W007096/2","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8775246936","display_name":null,"funder_award_id":"203148/Z/16/Z","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G8787748348","display_name":null,"funder_award_id":"203148/Z/16/Z","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8792368603","display_name":null,"funder_award_id":"MR/T018119/1","funder_id":"https://openalex.org/F4320314731","funder_display_name":"UK Research and Innovation"},{"id":"https://openalex.org/G8807293646","display_name":null,"funder_award_id":"V034537","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320314731","display_name":"UK Research and Innovation","ror":"https://ror.org/001aqnf71"},{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320325311","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320335827","display_name":"UCLH Biomedical Research Centre","ror":"https://ror.org/03r9qc142"},{"id":"https://openalex.org/F4320337314","display_name":"Centre For Medical Engineering, King\u2019s College London","ror":"https://ror.org/04s9kfd63"},{"id":"https://openalex.org/F6625209195","display_name":"Wellcome Leap","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":93,"referenced_works":["https://openalex.org/W999207820","https://openalex.org/W1535712589","https://openalex.org/W1550302139","https://openalex.org/W1582283219","https://openalex.org/W1965210407","https://openalex.org/W1970624991","https://openalex.org/W1978848720","https://openalex.org/W1979071912","https://openalex.org/W1984241541","https://openalex.org/W1986658111","https://openalex.org/W1987734559","https://openalex.org/W1988321289","https://openalex.org/W1995931314","https://openalex.org/W2010570746","https://openalex.org/W2015877503","https://openalex.org/W2019997266","https://openalex.org/W2025493057","https://openalex.org/W2027906762","https://openalex.org/W2034871524","https://openalex.org/W2049962258","https://openalex.org/W2085178516","https://openalex.org/W2105307297","https://openalex.org/W2108775200","https://openalex.org/W2113103631","https://openalex.org/W2130807679","https://openalex.org/W2134494674","https://openalex.org/W2137165337","https://openalex.org/W2143847855","https://openalex.org/W2144225673","https://openalex.org/W2144610339","https://openalex.org/W2164318788","https://openalex.org/W2166316739","https://openalex.org/W2226113296","https://openalex.org/W2265087599","https://openalex.org/W2312435147","https://openalex.org/W2414039468","https://openalex.org/W2416912191","https://openalex.org/W2417890937","https://openalex.org/W2474710771","https://openalex.org/W2519262228","https://openalex.org/W2576177109","https://openalex.org/W2594322393","https://openalex.org/W2711122980","https://openalex.org/W2774687577","https://openalex.org/W2796750894","https://openalex.org/W2799500525","https://openalex.org/W2888745236","https://openalex.org/W2889907839","https://openalex.org/W2895680199","https://openalex.org/W2896585601","https://openalex.org/W2898259843","https://openalex.org/W2898928934","https://openalex.org/W2901826627","https://openalex.org/W2911518407","https://openalex.org/W2921301179","https://openalex.org/W2922645839","https://openalex.org/W2948245246","https://openalex.org/W2950753216","https://openalex.org/W2960665032","https://openalex.org/W2963083301","https://openalex.org/W2963806356","https://openalex.org/W2967389958","https://openalex.org/W2970846294","https://openalex.org/W2970875462","https://openalex.org/W2973617105","https://openalex.org/W2975753565","https://openalex.org/W2979848484","https://openalex.org/W2982389986","https://openalex.org/W2998423108","https://openalex.org/W3008743760","https://openalex.org/W3018712052","https://openalex.org/W3020359021","https://openalex.org/W3026983534","https://openalex.org/W3036703284","https://openalex.org/W3036841898","https://openalex.org/W3038717165","https://openalex.org/W3047048295","https://openalex.org/W3104076520","https://openalex.org/W3130174200","https://openalex.org/W3134526910","https://openalex.org/W3136970255","https://openalex.org/W3160092929","https://openalex.org/W3213375106","https://openalex.org/W4200277868","https://openalex.org/W4220821822","https://openalex.org/W4220851455","https://openalex.org/W4234665825","https://openalex.org/W4244010575","https://openalex.org/W4285795824","https://openalex.org/W4316661944","https://openalex.org/W4391672942","https://openalex.org/W4392203593","https://openalex.org/W6911160354"],"related_works":["https://openalex.org/W3129816939","https://openalex.org/W2912862995","https://openalex.org/W2985427592","https://openalex.org/W2101501829","https://openalex.org/W2090583597","https://openalex.org/W2389974487","https://openalex.org/W2412883775","https://openalex.org/W2364920504","https://openalex.org/W271579791","https://openalex.org/W4296025728"],"abstract_inverted_index":{"The":[0,121],"placenta":[1],"is":[2,123,133,188],"crucial":[3],"for":[4,35,86,96,229],"a":[5,92,118,173],"successful":[6],"pregnancy,":[7],"facilitating":[8],"oxygen":[9],"exchange":[10],"and":[11,16,23,53,58,116,132,146,157,169,227],"nutrient":[12],"transport":[13],"between":[14],"mother":[15],"fetus.":[17],"Complications":[18],"like":[19,82],"fetal":[20],"growth":[21],"restriction":[22],"pre-eclampsia":[24],"are":[25],"linked":[26],"to":[27,66],"placental":[28,39,88,182,239],"vascular":[29,48,183,193,219,225],"structure":[30],"abnormalities,":[31],"highlighting":[32],"the":[33,68,178,181,201,230,233],"need":[34],"early":[36],"detection":[37],"of":[38,104,180,232,235],"health":[40],"issues.":[41],"Computational":[42],"modelling":[43],"offers":[44],"insights":[45],"into":[46],"how":[47,165],"architecture":[49,179],"correlates":[50],"with":[51,153,195],"flow":[52],"oxygenation":[54],"in":[55,98,154,176,190,241],"both":[56,107],"healthy":[57],"dysfunctional":[59],"placentas.":[60],"These":[61],"models":[62],"use":[63],"synthetic":[64],"networks":[65],"represent":[67],"multiscale":[69],"feto-placental":[70,105],"vasculature,":[71],"but":[72],"current":[73],"methods":[74],"lack":[75],"direct":[76,212],"control":[77,213],"over":[78,214],"key":[79,137,215],"morphological":[80,216,236],"parameters":[81,237],"branching":[83,127,144,170],"angles,":[84],"essential":[85],"predicting":[87],"dysfunction.":[89],"We":[90],"introduce":[91],"novel":[93],"generative":[94],"algorithm":[95,122,149],"creating":[97],"silico":[99],"placentas,":[100],"allowing":[101,228],"user-controlled":[102],"customisation":[103],"vasculatures,":[106],"as":[108,117],"individual":[109],"components":[110],"(placental":[111],"shape,":[112],"chorionic":[113],"vessels,":[114],"placentone)":[115],"complete":[119],"structure.":[120],"physiologically":[124],"underpinned,":[125],"following":[126],"laws":[128],"(i.e.":[129],"Murray's":[130],"Law),":[131],"defined":[134],"by":[135],"four":[136],"morphometric":[138],"statistics:":[139],"vessel":[140,142,166],"diameter,":[141],"length,":[143],"angle":[145],"asymmetry.":[147],"Our":[148,161],"produces":[150],"structures":[151,194,220],"consistent":[152],"vivo":[155,159],"measurements":[156],"ex":[158],"observations.":[160],"sensitivity":[162],"analysis":[163],"highlights":[164],"length":[167],"variations":[168],"angles":[171],"play":[172],"pivotal":[174],"role":[175],"defining":[177],"network.":[184],"Moreover,":[185],"our":[186,209],"approach":[187,210],"stochastic":[189],"nature,":[191],"yielding":[192],"different":[196],"topological":[197],"metrics":[198],"when":[199],"imposing":[200],"same":[202],"input":[203],"settings.":[204],"Unlike":[205],"previous":[206],"volume-filling":[207],"algorithms,":[208],"allows":[211],"parameters,":[217],"generating":[218],"that":[221],"closely":[222],"resemble":[223],"real":[224],"densities":[226],"investigation":[231],"impact":[234],"on":[238],"function":[240],"upcoming":[242],"studies.":[243]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}
