{"id":"https://openalex.org/W4401743650","doi":"https://doi.org/10.1371/journal.pcbi.1012399","title":"iCRBP-LKHA: Large convolutional kernel and hybrid channel-spatial attention for identifying circRNA-RBP interaction sites","display_name":"iCRBP-LKHA: Large convolutional kernel and hybrid channel-spatial attention for identifying circRNA-RBP interaction sites","publication_year":2024,"publication_date":"2024-08-22","ids":{"openalex":"https://openalex.org/W4401743650","doi":"https://doi.org/10.1371/journal.pcbi.1012399","pmid":"https://pubmed.ncbi.nlm.nih.gov/39173070"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1012399","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1012399","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1371/journal.pcbi.1012399","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101924090","display_name":"Lin Yuan","orcid":"https://orcid.org/0000-0002-9694-8191"},"institutions":[{"id":"https://openalex.org/I152269853","display_name":"Qilu University of Technology","ror":"https://ror.org/04hyzq608","country_code":"CN","type":"education","lineage":["https://openalex.org/I152269853"]},{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210142748","display_name":"Shandong Academy of Sciences","ror":"https://ror.org/04y8d6y55","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210142748"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lin Yuan","raw_affiliation_strings":["Key Laboratory of Computing Power Network and Information Security, Ministry of Education, Shandong Computer Science Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","Shandong Engineering Research Center of Big Data Applied Technology, Faculty of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","Shandong Provincial Key Laboratory of Computer Networks, Shandong Fundamental Research Center for Computer Science, Jinan, China"],"raw_orcid":"https://orcid.org/0000-0002-9694-8191","affiliations":[{"raw_affiliation_string":"Key Laboratory of Computing Power Network and Information Security, Ministry of Education, Shandong Computer Science Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","institution_ids":["https://openalex.org/I152269853","https://openalex.org/I4210142748"]},{"raw_affiliation_string":"Shandong Engineering Research Center of Big Data Applied Technology, Faculty of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","institution_ids":["https://openalex.org/I4210142748","https://openalex.org/I152269853"]},{"raw_affiliation_string":"Shandong Provincial Key Laboratory of Computer Networks, Shandong Fundamental Research Center for Computer Science, Jinan, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101571058","display_name":"Ling Zhao","orcid":"https://orcid.org/0000-0002-9888-788X"},"institutions":[{"id":"https://openalex.org/I152269853","display_name":"Qilu University of Technology","ror":"https://ror.org/04hyzq608","country_code":"CN","type":"education","lineage":["https://openalex.org/I152269853"]},{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210142748","display_name":"Shandong Academy of Sciences","ror":"https://ror.org/04y8d6y55","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210142748"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ling Zhao","raw_affiliation_strings":["Key Laboratory of Computing Power Network and Information Security, Ministry of Education, Shandong Computer Science Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","Shandong Engineering Research Center of Big Data Applied Technology, Faculty of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","Shandong Provincial Key Laboratory of Computer Networks, Shandong Fundamental Research Center for Computer Science, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Computing Power Network and Information Security, Ministry of Education, Shandong Computer Science Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","institution_ids":["https://openalex.org/I152269853","https://openalex.org/I4210142748"]},{"raw_affiliation_string":"Shandong Engineering Research Center of Big Data Applied Technology, Faculty of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","institution_ids":["https://openalex.org/I4210142748","https://openalex.org/I152269853"]},{"raw_affiliation_string":"Shandong Provincial Key Laboratory of Computer Networks, Shandong Fundamental Research Center for Computer Science, Jinan, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036263954","display_name":"Jinling Lai","orcid":null},"institutions":[{"id":"https://openalex.org/I152269853","display_name":"Qilu University of Technology","ror":"https://ror.org/04hyzq608","country_code":"CN","type":"education","lineage":["https://openalex.org/I152269853"]},{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210142748","display_name":"Shandong Academy of Sciences","ror":"https://ror.org/04y8d6y55","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210142748"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jinling Lai","raw_affiliation_strings":["Key Laboratory of Computing Power Network and Information Security, Ministry of Education, Shandong Computer Science Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","Shandong Engineering Research Center of Big Data Applied Technology, Faculty of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","Shandong Provincial Key Laboratory of Computer Networks, Shandong Fundamental Research Center for Computer Science, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Computing Power Network and Information Security, Ministry of Education, Shandong Computer Science Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","institution_ids":["https://openalex.org/I152269853","https://openalex.org/I4210142748"]},{"raw_affiliation_string":"Shandong Engineering Research Center of Big Data Applied Technology, Faculty of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","institution_ids":["https://openalex.org/I4210142748","https://openalex.org/I152269853"]},{"raw_affiliation_string":"Shandong Provincial Key Laboratory of Computer Networks, Shandong Fundamental Research Center for Computer Science, Jinan, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051199839","display_name":"Yufeng Jiang","orcid":"https://orcid.org/0000-0003-4553-4834"},"institutions":[{"id":"https://openalex.org/I152269853","display_name":"Qilu University of Technology","ror":"https://ror.org/04hyzq608","country_code":"CN","type":"education","lineage":["https://openalex.org/I152269853"]},{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210142748","display_name":"Shandong Academy of Sciences","ror":"https://ror.org/04y8d6y55","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210142748"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yufeng Jiang","raw_affiliation_strings":["Key Laboratory of Computing Power Network and Information Security, Ministry of Education, Shandong Computer Science Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","Shandong Engineering Research Center of Big Data Applied Technology, Faculty of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","Shandong Provincial Key Laboratory of Computer Networks, Shandong Fundamental Research Center for Computer Science, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Computing Power Network and Information Security, Ministry of Education, Shandong Computer Science Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","institution_ids":["https://openalex.org/I152269853","https://openalex.org/I4210142748"]},{"raw_affiliation_string":"Shandong Engineering Research Center of Big Data Applied Technology, Faculty of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China","institution_ids":["https://openalex.org/I4210142748","https://openalex.org/I152269853"]},{"raw_affiliation_string":"Shandong Provincial Key Laboratory of Computer Networks, Shandong Fundamental Research Center for Computer Science, Jinan, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062540383","display_name":"Qinhu Zhang","orcid":"https://orcid.org/0000-0002-4232-7736"},"institutions":[{"id":"https://openalex.org/I4394709157","display_name":"Eastern Institute of Technology, Ningbo","ror":"https://ror.org/036mbz113","country_code":null,"type":"education","lineage":["https://openalex.org/I4394709157"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qinhu Zhang","raw_affiliation_strings":["Eastern Institute for Advanced Study, Eastern Institute of Technology, Ningbo, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eastern Institute for Advanced Study, Eastern Institute of Technology, Ningbo, China","institution_ids":["https://openalex.org/I4394709157"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089051425","display_name":"Zhen Shen","orcid":"https://orcid.org/0000-0001-7572-9195"},"institutions":[{"id":"https://openalex.org/I4210115515","display_name":"Nanyang Institute of Technology","ror":"https://ror.org/0203c2755","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210115515"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhen Shen","raw_affiliation_strings":["School of Computer and Software, Nanyang Institute of Technology, Nanyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer and Software, Nanyang Institute of Technology, Nanyang, China","institution_ids":["https://openalex.org/I4210115515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064185915","display_name":"Chun-Hou Zheng","orcid":"https://orcid.org/0000-0002-2695-1926"},"institutions":[{"id":"https://openalex.org/I143868143","display_name":"Anhui University","ror":"https://ror.org/05th6yx34","country_code":"CN","type":"education","lineage":["https://openalex.org/I143868143"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chun-Hou Zheng","raw_affiliation_strings":["Key Lab of Intelligent Computing and Signal Processing of Ministry of Education, School of Artificial Intelligence, Anhui University, Hefei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Lab of Intelligent Computing and Signal Processing of Ministry of Education, School of Artificial Intelligence, Anhui University, Hefei, China","institution_ids":["https://openalex.org/I143868143"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060381913","display_name":"De-Shuang Huang","orcid":"https://orcid.org/0000-0002-6759-2691"},"institutions":[{"id":"https://openalex.org/I4394709157","display_name":"Eastern Institute of Technology, Ningbo","ror":"https://ror.org/036mbz113","country_code":null,"type":"education","lineage":["https://openalex.org/I4394709157"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"De-Shuang Huang","raw_affiliation_strings":["Eastern Institute for Advanced Study, Eastern Institute of Technology, Ningbo, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eastern Institute for Advanced Study, Eastern Institute of Technology, Ningbo, China","institution_ids":["https://openalex.org/I4394709157"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5036263954","https://openalex.org/A5051199839","https://openalex.org/A5060381913","https://openalex.org/A5062540383","https://openalex.org/A5064185915","https://openalex.org/A5089051425","https://openalex.org/A5101571058","https://openalex.org/A5101924090"],"corresponding_institution_ids":["https://openalex.org/I143868143","https://openalex.org/I152269853","https://openalex.org/I154099455","https://openalex.org/I4210115515","https://openalex.org/I4210142748","https://openalex.org/I4394709157"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":5.2436,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.96507476,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"20","issue":"8","first_page":"e1012399","last_page":"e1012399"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9678999781608582,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.9664000272750854,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6881656050682068},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.6097965240478516},{"id":"https://openalex.org/keywords/kernel","display_name":"Kernel (algebra)","score":0.5646858215332031},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5429392457008362},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5056607723236084},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.4867129623889923},{"id":"https://openalex.org/keywords/encoding","display_name":"Encoding (memory)","score":0.4439116418361664},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3973255753517151},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3841398060321808},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3576838970184326},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.16396456956863403},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.13285785913467407}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6881656050682068},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.6097965240478516},{"id":"https://openalex.org/C74193536","wikidata":"https://www.wikidata.org/wiki/Q574844","display_name":"Kernel (algebra)","level":2,"score":0.5646858215332031},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5429392457008362},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5056607723236084},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.4867129623889923},{"id":"https://openalex.org/C125411270","wikidata":"https://www.wikidata.org/wiki/Q18653","display_name":"Encoding (memory)","level":2,"score":0.4439116418361664},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3973255753517151},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3841398060321808},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3576838970184326},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16396456956863403},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.13285785913467407},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pcbi.1012399","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1012399","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:39173070","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39173070","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11373821","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11373821","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11373821/pdf/pcbi.1012399.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:RePEc:plo:pcbi00:1012399","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1012399","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:4ceb37f9b5fc4afab0f3925f42072fb6","is_oa":false,"landing_page_url":"https://doaj.org/article/4ceb37f9b5fc4afab0f3925f42072fb6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 20, Iss 8, p e1012399 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1012399","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1012399","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1141093333","display_name":null,"funder_award_id":"2021JJA170199","funder_id":"https://openalex.org/F4320322768","funder_display_name":"Natural Science Foundation of Guangxi Province"},{"id":"https://openalex.org/G1307575636","display_name":null,"funder_award_id":"61932008","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1857610291","display_name":null,"funder_award_id":"62073231","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2757684404","display_name":null,"funder_award_id":"62102200","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5280656057","display_name":null,"funder_award_id":"62372318","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6059964893","display_name":null,"funder_award_id":"STI 2030","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6332332648","display_name":null,"funder_award_id":"62002189","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G643023014","display_name":null,"funder_award_id":"62372255","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7699868062","display_name":null,"funder_award_id":"2021JJA170204","funder_id":"https://openalex.org/F4320322768","funder_display_name":"Natural Science Foundation of Guangxi Province"},{"id":"https://openalex.org/G7894669521","display_name":null,"funder_award_id":"U22A2039","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7969017031","display_name":null,"funder_award_id":"2023J199","funder_id":"https://openalex.org/F4320332587","funder_display_name":"Natural Science Foundation of Ningbo"},{"id":"https://openalex.org/G8263092845","display_name":null,"funder_award_id":"2023M733400","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G8789459265","display_name":null,"funder_award_id":"62333018, 62372255, U22A2039, 62073231, 61932008, 62372318","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G906490537","display_name":null,"funder_award_id":"62333018","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320308724","display_name":"Texas Space Grant Consortium","ror":"https://ror.org/05k1jx057"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320322768","display_name":"Natural Science Foundation of Guangxi Province","ror":null},{"id":"https://openalex.org/F4320324887","display_name":"Shandong Academy of Sciences","ror":"https://ror.org/04y8d6y55"},{"id":"https://openalex.org/F4320328720","display_name":"Qilu University of Technology","ror":"https://ror.org/04hyzq608"},{"id":"https://openalex.org/F4320332587","display_name":"Natural Science Foundation of Ningbo","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W7721663","https://openalex.org/W1584707462","https://openalex.org/W2008056655","https://openalex.org/W2053758959","https://openalex.org/W2089468765","https://openalex.org/W2131774270","https://openalex.org/W2150757437","https://openalex.org/W2156125289","https://openalex.org/W2183672689","https://openalex.org/W2285139619","https://openalex.org/W2295598076","https://openalex.org/W2415310056","https://openalex.org/W2419834209","https://openalex.org/W2547759798","https://openalex.org/W2556967412","https://openalex.org/W2622004629","https://openalex.org/W2768348081","https://openalex.org/W2792481260","https://openalex.org/W2799487719","https://openalex.org/W2884585870","https://openalex.org/W2911964244","https://openalex.org/W2941190338","https://openalex.org/W2949846184","https://openalex.org/W2950463913","https://openalex.org/W2970645663","https://openalex.org/W2973586775","https://openalex.org/W2981242070","https://openalex.org/W2984339599","https://openalex.org/W2986421215","https://openalex.org/W2991019646","https://openalex.org/W3021512994","https://openalex.org/W3026425509","https://openalex.org/W3095596981","https://openalex.org/W3146366485","https://openalex.org/W3197730739","https://openalex.org/W4200074879","https://openalex.org/W4206826027","https://openalex.org/W4207079529","https://openalex.org/W4210852391","https://openalex.org/W4213138800","https://openalex.org/W4280638470","https://openalex.org/W4283380697","https://openalex.org/W4296580708","https://openalex.org/W4324129712","https://openalex.org/W4379932619","https://openalex.org/W4391280459","https://openalex.org/W4391296859","https://openalex.org/W4391343199","https://openalex.org/W4393972784","https://openalex.org/W6753412334"],"related_works":["https://openalex.org/W4293226380","https://openalex.org/W4321487865","https://openalex.org/W4313906399","https://openalex.org/W4391266461","https://openalex.org/W2590798552","https://openalex.org/W2811106690","https://openalex.org/W4239306820","https://openalex.org/W2947043951","https://openalex.org/W4312417841","https://openalex.org/W4235381733"],"abstract_inverted_index":{"Circular":[0],"RNAs":[1,170],"(circRNAs)":[2],"play":[3],"vital":[4],"roles":[5],"in":[6,22,192],"transcription":[7],"and":[8,24,39,52,108,121,145,167],"translation.":[9],"Identification":[10],"of":[11,59,93,131,189],"circRNA-RBP":[12,36,78],"(RNA-binding":[13],"protein)":[14],"interaction":[15,37,57,79,124,196],"sites":[16,38],"has":[17],"become":[18],"a":[19,68],"fundamental":[20],"step":[21],"molecular":[23],"cell":[25],"biology.":[26],"Deep":[27],"learning":[28,139],"(DL)-based":[29],"methods":[30,46,158],"have":[31],"been":[32],"proposed":[33],"to":[34],"predict":[35],"achieved":[40],"impressive":[41],"identification":[42],"performance.":[43],"However,":[44],"those":[45,64],"cannot":[47,53],"effectively":[48,54],"capture":[49],"long-distance":[50],"dependencies,":[51],"utilize":[55],"the":[56,87,129,187],"information":[58,120,125],"multiple":[60,122],"features.":[61],"To":[62,127],"overcome":[63],"limitations,":[65],"we":[66,133,151],"propose":[67],"DL-based":[69,157],"model":[70,191],"iCRBP-LKHA":[71,81,179],"using":[72],"deep":[73],"hybrid":[74],"networks":[75],"for":[76],"identifying":[77,193],"sites.":[80,197],"adopts":[82],"five":[83],"encoding":[84],"schemes.":[85],"Meanwhile,":[86],"neural":[88,97],"network":[89,98],"architecture,":[90],"which":[91],"consists":[92],"large":[94],"kernel":[95],"convolutional":[96,100],"(LKCNN),":[99],"block":[101],"attention":[102],"module":[103],"with":[104,137,155],"one-dimensional":[105],"convolution":[106],"(CBAM-1D)":[107],"bidirectional":[109],"gating":[110],"recurrent":[111],"unit":[112],"(BiGRU),":[113],"can":[114],"explore":[115],"local":[116],"information,":[117],"global":[118],"context":[119],"features":[123],"automatically.":[126],"verify":[128],"effectiveness":[130],"iCRBP-LKHA,":[132],"compared":[134,152],"its":[135,153],"performance":[136,154],"shallow":[138],"algorithms":[140],"on":[141,159],"37":[142,146,160,163],"circRNAs":[143,147,161,164],"datasets":[144,166],"stringent":[148,165],"datasets.":[149,171],"And":[150],"state-of-the-art":[156],"datasets,":[162],"31":[168],"linear":[169],"The":[172],"experimental":[173],"results":[174],"not":[175],"only":[176],"show":[177],"that":[178],"outperforms":[180],"other":[181,194],"competing":[182],"methods,":[183],"but":[184],"also":[185],"demonstrate":[186],"potential":[188],"this":[190],"RNA-RBP":[195]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":17},{"year":2024,"cited_by_count":2}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}