{"id":"https://openalex.org/W4408025849","doi":"https://doi.org/10.1371/journal.pcbi.1012055","title":"Impact of increased diagnosis of early HIV infection and immediate antiretroviral treatment initiation on HIV transmission among men who have sex with men in the Netherlands","display_name":"Impact of increased diagnosis of early HIV infection and immediate antiretroviral treatment initiation on HIV transmission among men who have sex with men in the Netherlands","publication_year":2025,"publication_date":"2025-02-27","ids":{"openalex":"https://openalex.org/W4408025849","doi":"https://doi.org/10.1371/journal.pcbi.1012055","pmid":"https://pubmed.ncbi.nlm.nih.gov/40014624"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1012055","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1012055","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1012055&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1012055&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040996223","display_name":"Alexandra Teslya","orcid":"https://orcid.org/0000-0002-3675-7377"},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Alexandra Teslya","raw_affiliation_strings":["Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916","https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089992869","display_name":"Janneke C. M. Heijne","orcid":"https://orcid.org/0009-0001-5005-9452"},"institutions":[{"id":"https://openalex.org/I4210148356","display_name":"GGD Amsterdam","ror":"https://ror.org/04gbbq803","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210088893","https://openalex.org/I4210148356"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Janneke Cornelia Maria Heijne","raw_affiliation_strings":["Amsterdam Institute for Immunology & Infectious Diseases (AII), Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands","Amsterdam Public Health Research Institute (APH), Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands","Department of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, The Netherlands","Department of Internal Medicine, Division of Infectious Diseases, Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Amsterdam Institute for Immunology & Infectious Diseases (AII), Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I887064364","https://openalex.org/I4210151833"]},{"raw_affiliation_string":"Amsterdam Public Health Research Institute (APH), Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210151833","https://openalex.org/I887064364"]},{"raw_affiliation_string":"Department of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210148356"]},{"raw_affiliation_string":"Department of Internal Medicine, Division of Infectious Diseases, Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210151833","https://openalex.org/I887064364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006833494","display_name":"Maarten F. Schim van der Loeff","orcid":"https://orcid.org/0000-0002-4903-7002"},"institutions":[{"id":"https://openalex.org/I4210120830","display_name":"Stichting HIV Monitoring","ror":"https://ror.org/02w6k4f12","country_code":"NL","type":"other","lineage":["https://openalex.org/I4210120830"]},{"id":"https://openalex.org/I4210148356","display_name":"GGD Amsterdam","ror":"https://ror.org/04gbbq803","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210088893","https://openalex.org/I4210148356"]},{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Maarten Franciscus Schim van der Loeff","raw_affiliation_strings":["Department of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, The Netherlands","Department of Internal Medicine, Division of Infectious Diseases, Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands","Stichting HIV Monitoring, Amsterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210148356"]},{"raw_affiliation_string":"Department of Internal Medicine, Division of Infectious Diseases, Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210151833","https://openalex.org/I887064364"]},{"raw_affiliation_string":"Stichting HIV Monitoring, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210120830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049260734","display_name":"Ard van Sighem","orcid":"https://orcid.org/0000-0002-6656-0516"},"institutions":[{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Ard van Sighem","raw_affiliation_strings":["Amsterdam UMC location University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Amsterdam UMC location University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210151833","https://openalex.org/I887064364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010071784","display_name":"Jacob Aiden Roberts","orcid":"https://orcid.org/0009-0009-6845-1119"},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Jacob Aiden Roberts","raw_affiliation_strings":["Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916","https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078730691","display_name":"Maartje Dijkstra","orcid":"https://orcid.org/0000-0003-2561-7659"},"institutions":[{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Maartje Dijkstra","raw_affiliation_strings":["Department of Internal Medicine, Division of Infectious Diseases, Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Division of Infectious Diseases, Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210151833","https://openalex.org/I887064364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047029696","display_name":"Godelieve J. de Bree","orcid":"https://orcid.org/0000-0002-5852-5833"},"institutions":[{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Godelieve J de Bree","raw_affiliation_strings":["Department of Internal Medicine, Division of Infectious Diseases, Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Division of Infectious Diseases, Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I4210151833","https://openalex.org/I887064364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071610501","display_name":"Axel J. Schmidt","orcid":"https://orcid.org/0000-0002-6910-4399"},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Axel Jeremias Schmidt","raw_affiliation_strings":["Medicine and Health Policy Unit, German AIDS Federation, Berlin, Germany","Sigma Research, Department of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Medicine and Health Policy Unit, German AIDS Federation, Berlin, Germany","institution_ids":[]},{"raw_affiliation_string":"Sigma Research, Department of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, United Kingdom","institution_ids":["https://openalex.org/I4210089966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049602140","display_name":"Kai J. Jonas","orcid":"https://orcid.org/0000-0001-6607-1993"},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Kai J Jonas","raw_affiliation_strings":["Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066320010","display_name":"Mirjam Kretzschmar","orcid":"https://orcid.org/0000-0002-4394-7697"},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["DE","NL"],"is_corresponding":true,"raw_author_name":"Mirjam E Kretzschmar","raw_affiliation_strings":["Center for Complex Systems Studies (CCSS), Utrecht University, Utrecht, The Netherlands","Institute of Epidemiology and Social Medicine, University of M\u00fcnster, M\u00fcnster, Germany","Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Center for Complex Systems Studies (CCSS), Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Institute of Epidemiology and Social Medicine, University of M\u00fcnster, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]},{"raw_affiliation_string":"Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916","https://openalex.org/I193662353"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076137504","display_name":"Ganna Rozhnova","orcid":"https://orcid.org/0000-0002-6725-7359"},"institutions":[{"id":"https://openalex.org/I141596103","display_name":"University of Lisbon","ror":"https://ror.org/01c27hj86","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103"]},{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL","PT"],"is_corresponding":true,"raw_author_name":"Ganna Rozhnova","raw_affiliation_strings":["BioISI - Biosystems & Integrative Sciences Institute, Faculdade de Ci\u00eancias, Universidade de Lisboa, Lisbon, Portugal","Center for Complex Systems Studies (CCSS), Utrecht University, Utrecht, The Netherlands","Faculdade de Ci\u00eancias, Universidade de Lisboa, Lisbon, Portugal","Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands","BioISI \u2013 Biosystems & Integrative Sciences Institute, Faculdade de Ci\u00eancias, Universidade de Lisboa, Lisbon, Portugal"],"affiliations":[{"raw_affiliation_string":"BioISI - Biosystems & Integrative Sciences Institute, Faculdade de Ci\u00eancias, Universidade de Lisboa, Lisbon, Portugal","institution_ids":["https://openalex.org/I141596103"]},{"raw_affiliation_string":"Center for Complex Systems Studies (CCSS), Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Faculdade de Ci\u00eancias, Universidade de Lisboa, Lisbon, Portugal","institution_ids":["https://openalex.org/I141596103"]},{"raw_affiliation_string":"Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916","https://openalex.org/I193662353"]},{"raw_affiliation_string":"BioISI \u2013 Biosystems & Integrative Sciences Institute, Faculdade de Ci\u00eancias, Universidade de Lisboa, Lisbon, Portugal","institution_ids":["https://openalex.org/I141596103"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5006833494","https://openalex.org/A5010071784","https://openalex.org/A5040996223","https://openalex.org/A5047029696","https://openalex.org/A5049260734","https://openalex.org/A5049602140","https://openalex.org/A5066320010","https://openalex.org/A5071610501","https://openalex.org/A5076137504","https://openalex.org/A5078730691","https://openalex.org/A5089992869"],"corresponding_institution_ids":["https://openalex.org/I141596103","https://openalex.org/I193662353","https://openalex.org/I22465464","https://openalex.org/I3018483916","https://openalex.org/I34352273","https://openalex.org/I4210089966","https://openalex.org/I4210120830","https://openalex.org/I4210148356","https://openalex.org/I4210151833","https://openalex.org/I887064364"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05569565,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"21","issue":"2","first_page":"e1012055","last_page":"e1012055"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11860","display_name":"HIV, Drug Use, Sexual Risk","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-immunodeficiency-virus","display_name":"Human immunodeficiency virus (HIV)","score":0.7645881175994873},{"id":"https://openalex.org/keywords/antiretroviral-treatment","display_name":"Antiretroviral treatment","score":0.6075767874717712},{"id":"https://openalex.org/keywords/transmission","display_name":"Transmission (telecommunications)","score":0.5516011118888855},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5252296924591064},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"Antiretroviral therapy","score":0.5200933218002319},{"id":"https://openalex.org/keywords/men-who-have-sex-with-men","display_name":"Men who have sex with men","score":0.4797191023826599},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.47954484820365906},{"id":"https://openalex.org/keywords/lentivirus","display_name":"Lentivirus","score":0.46169981360435486},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.35628676414489746},{"id":"https://openalex.org/keywords/viral-load","display_name":"Viral load","score":0.3432466983795166},{"id":"https://openalex.org/keywords/viral-disease","display_name":"Viral disease","score":0.2247210144996643},{"id":"https://openalex.org/keywords/syphilis","display_name":"Syphilis","score":0.08673974871635437}],"concepts":[{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.7645881175994873},{"id":"https://openalex.org/C3019165603","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral treatment","level":5,"score":0.6075767874717712},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.5516011118888855},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5252296924591064},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.5200933218002319},{"id":"https://openalex.org/C2776939746","wikidata":"https://www.wikidata.org/wiki/Q853451","display_name":"Men who have sex with men","level":4,"score":0.4797191023826599},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.47954484820365906},{"id":"https://openalex.org/C2779690655","wikidata":"https://www.wikidata.org/wiki/Q374232","display_name":"Lentivirus","level":4,"score":0.46169981360435486},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35628676414489746},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.3432466983795166},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.2247210144996643},{"id":"https://openalex.org/C2776983459","wikidata":"https://www.wikidata.org/wiki/Q41083","display_name":"Syphilis","level":3,"score":0.08673974871635437},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012725","descriptor_name":"Sexual Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012725","descriptor_name":"Sexual Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012725","descriptor_name":"Sexual Behavior","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D012725","descriptor_name":"Sexual Behavior","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D012725","descriptor_name":"Sexual Behavior","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000635","qualifier_name":"transmission","is_major_topic":true},{"descriptor_ui":"D018451","descriptor_name":"Homosexuality, Male","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D018451","descriptor_name":"Homosexuality, Male","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D018451","descriptor_name":"Homosexuality, Male","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D018451","descriptor_name":"Homosexuality, Male","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D018451","descriptor_name":"Homosexuality, Male","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044966","descriptor_name":"Anti-Retroviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D044966","descriptor_name":"Anti-Retroviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D044966","descriptor_name":"Anti-Retroviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D044966","descriptor_name":"Anti-Retroviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D044966","descriptor_name":"Anti-Retroviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1012055","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1012055","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1012055&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:40014624","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40014624","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/c2c24665-237c-48f2-8af2-4a94c60a7b02","is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/c2c24665-237c-48f2-8af2-4a94c60a7b02","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Teslya, A, Heijne, J C M, van der Loeff, M F S, van Sighem, A, Roberts, J A, Dijkstra, M, de Bree, G J, Schmidt, A J, Jonas, K J, Kretzschmar, M E & Rozhnova, G 2025, 'Impact of increased diagnosis of early HIV infection and immediate antiretroviral treatment initiation on HIV transmission among men who have sex with men in the Netherlands', PLoS Computational Biology, vol. 21, no. 2, e1012055. https://doi.org/10.1371/journal.pcbi.1012055","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire/aed41e2b-a576-4cf8-8615-009d9c7aafac","is_oa":true,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/aed41e2b-a576-4cf8-8615-009d9c7aafac","pdf_url":"https://pure.amsterdamumc.nl/files/138555067/Impact-of-increased-diagnosis-of-early-hiv-infection-and-immediate-antiretroviral-treatment-initiation-on-hiv-transmissi.pdf","source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Teslya, A, Heijne, J C M, van der Loeff, M F S, van Sighem, A, Roberts, J A, Dijkstra, M, de Bree, G J, Schmidt, A J, Jonas, K J, Kretzschmar, M E & Rozhnova, G 2025, 'Impact of increased diagnosis of early HIV infection and immediate antiretroviral treatment initiation on HIV transmission among men who have sex with men in the Netherlands', PLoS computational biology, vol. 21, no. 2 February, e1012055. https://doi.org/10.1371/journal.pcbi.1012055","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:researchonline.lshtm.ac.uk:4677090","is_oa":true,"landing_page_url":"https://orcid.org/0000-0002-3675-7377>;","pdf_url":"https://researchonline.lshtm.ac.uk/id/eprint/4677090/1/Teslya-etal-2025-Impact-of-increased-diagnosis.pdf","source":{"id":"https://openalex.org/S4306402527","display_name":"LSHTM Research Online (London School of Hygiene and Tropical Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210089966","host_organization_name":"London School of Hygiene & Tropical Medicine","host_organization_lineage":["https://openalex.org/I4210089966"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},{"id":"pmh:oai:doaj.org/article:c508428a8c6b4220a4980ddd03a1b82c","is_oa":true,"landing_page_url":"https://doaj.org/article/c508428a8c6b4220a4980ddd03a1b82c","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 21, Iss 2, p e1012055 (2025)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11882050","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11882050","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1012055","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1012055","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1012055&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8100000023841858,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G5170744538","display_name":null,"funder_award_id":"P-53902","funder_id":"https://openalex.org/F4320309881","funder_display_name":"Aids Fonds"}],"funders":[{"id":"https://openalex.org/F4320309881","display_name":"Aids Fonds","ror":"https://ror.org/00j04c011"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4408025849.pdf"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1993748863","https://openalex.org/W2056790245","https://openalex.org/W2071613821","https://openalex.org/W2117775533","https://openalex.org/W2126141460","https://openalex.org/W2136147480","https://openalex.org/W2141724890","https://openalex.org/W2147943363","https://openalex.org/W2154353570","https://openalex.org/W2227250608","https://openalex.org/W2238552371","https://openalex.org/W2314893245","https://openalex.org/W2479620747","https://openalex.org/W2732030379","https://openalex.org/W2733342689","https://openalex.org/W2766208102","https://openalex.org/W2767270400","https://openalex.org/W2883540434","https://openalex.org/W2898225236","https://openalex.org/W2899233430","https://openalex.org/W2928141264","https://openalex.org/W2996048578","https://openalex.org/W3023630990","https://openalex.org/W3161971860","https://openalex.org/W4224086297","https://openalex.org/W4285094298","https://openalex.org/W4318678052","https://openalex.org/W4365442858","https://openalex.org/W4391221146","https://openalex.org/W4401793996"],"related_works":["https://openalex.org/W2082435118","https://openalex.org/W2896882709","https://openalex.org/W4392711781","https://openalex.org/W2791153793","https://openalex.org/W2472539340","https://openalex.org/W2128788690","https://openalex.org/W4311890712","https://openalex.org/W2498302066","https://openalex.org/W2103105658","https://openalex.org/W4285274131"],"abstract_inverted_index":{"The":[0,117],"number":[1],"of":[2,37,40,102,120,157,166,184,209,217,224,252,257],"new":[3,159,210],"HIV":[4,42,53,64,87,97,138,152,160,191,211,233,261,267,272],"infections":[5,139,161,174,212],"among":[6,55,284],"men":[7,12],"who":[8,189],"have":[9],"sex":[10],"with":[11,45,259],"(MSM)":[13],"in":[14,72,75,78,131,144,169,202,240],"the":[15,35,73,90,121,132,145,182,185,194,203,221,225,246,248],"Netherlands":[16,74],"has":[17],"been":[18],"decreasing,":[19],"but":[20],"additional":[21],"efforts":[22],"are":[23],"required":[24],"to":[25,33,63,129,155,187,207,245],"bring":[26],"it":[27],"further":[28,281],"down.":[29],"This":[30],"study":[31],"aims":[32],"assess":[34],"impact":[36,123,223],"increased":[38,103,275],"diagnosis":[39,88,104,146,204,256,273],"early":[41,260,271],"infection":[43,192,262],"combined":[44],"immediate":[46,114,250],"antiretroviral":[47],"treatment":[48],"(ART)":[49],"initiation":[50,251],"on":[51],"reducing":[52],"transmission":[54,268,283],"MSM.":[56,285],"We":[57],"developed":[58],"an":[59,241],"agent-based":[60],"model":[61],"calibrated":[62],"surveillance":[65],"and":[66,110,278],"sexual":[67],"behavior":[68],"data":[69],"for":[70],"MSM":[71],"2017-2022.":[76],"Starting":[77],"2023,":[79],"we":[80],"simulated":[81],"a":[82,198,290],"10-year":[83],"intervention":[84,186,226],"that":[85],"accelerates":[86],"during":[89],"first":[91],"3":[92,149,164],"or":[93],"6":[94,196,215],"months":[95,150,165,216],"after":[96,151],"acquisition":[98,153],"across":[99],"five":[100],"levels":[101],"rates":[105],"(2,":[106],"4,":[107],"8,":[108],"16,":[109],"32-fold),":[111],"followed":[112],"by":[113,227],"ART":[115,253],"initiation.":[116],"upper":[118],"limit":[119],"intervention's":[122],"over":[124],"10":[125],"years":[126],"is":[127],"projected":[128],"result":[130],"cumulative":[133],"298":[134],"(95-th":[135,171,230],"QI:":[136,172,231],"162-451)":[137],"averted.":[140],"A":[141],"32-fold":[142],"increase":[143,201],"rate":[147,205],"within":[148,163,193,214],"(corresponding":[154,206],"100%":[156],"all":[158],"diagnosed":[162,213],"acquisition)":[167,218],"results":[168],"269":[170],"147-400)":[173],"averted,":[175],"approaching":[176],"closely":[177,220],"maximum":[178,222],"impact.":[179],"By":[180],"extending":[181],"scope":[183],"individuals":[188,258],"acquired":[190],"previous":[195],"months,":[197],"smaller":[199],"8-fold":[200],"97%":[208],"approaches":[219],"averting":[228],"256":[229],"122-411)":[232],"infections.":[234],"Our":[235],"sensitivity":[236],"analyses":[237],"showed":[238],"that,":[239],"epidemiological":[242],"context":[243],"similar":[244],"modern-day":[247],"Netherlands,":[249],"accompanying":[254],"accelerated":[255],"does":[263],"not":[264],"significantly":[265],"affect":[266],"dynamics.":[269],"Accelerating":[270],"through":[274],"awareness,":[276],"screening,":[277],"testing":[279],"can":[280],"reduce":[282],"Meeting":[286],"this":[287],"goal":[288],"necessitates":[289],"stakeholder":[291],"needs":[292],"assessment.":[293]},"counts_by_year":[],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}