{"id":"https://openalex.org/W4313455209","doi":"https://doi.org/10.1371/journal.pcbi.1010816","title":"Neutral vs. non-neutral genetic footprints of Plasmodium falciparum multiclonal infections","display_name":"Neutral vs. non-neutral genetic footprints of Plasmodium falciparum multiclonal infections","publication_year":2023,"publication_date":"2023-01-03","ids":{"openalex":"https://openalex.org/W4313455209","doi":"https://doi.org/10.1371/journal.pcbi.1010816","pmid":"https://pubmed.ncbi.nlm.nih.gov/36595546"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1010816","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010816","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1371/journal.pcbi.1010816","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015206026","display_name":"Fr\u00e9d\u00e9ric Labb\u00e9","orcid":"https://orcid.org/0000-0002-4064-2361"},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Fr\u00e9d\u00e9ric Labb\u00e9","raw_affiliation_strings":["Department of Ecology and Evolution, The University of Chicago, Chicago, Illinois, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Ecology and Evolution, The University of Chicago, Chicago, Illinois, United States of America","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028427304","display_name":"Qixin He","orcid":"https://orcid.org/0000-0003-1696-8203"},"institutions":[{"id":"https://openalex.org/I55769427","display_name":"Indiana University \u2013 Purdue University Indianapolis","ror":"https://ror.org/05gxnyn08","country_code":"US","type":"education","lineage":["https://openalex.org/I55769427","https://openalex.org/I592451"]},{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Qixin He","raw_affiliation_strings":["Department of Biological Sciences, Purdue University, West Lafayette, Indianapolis, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Purdue University, West Lafayette, Indianapolis, United States of America","institution_ids":["https://openalex.org/I219193219","https://openalex.org/I55769427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100664084","display_name":"Qi Zhang","orcid":"https://orcid.org/0000-0002-2239-4333"},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Qi Zhan","raw_affiliation_strings":["Department of Ecology and Evolution, The University of Chicago, Chicago, Illinois, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Ecology and Evolution, The University of Chicago, Chicago, Illinois, United States of America","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047487804","display_name":"Kathryn E. Tiedje","orcid":"https://orcid.org/0000-0003-3305-0533"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Kathryn E. Tiedje","raw_affiliation_strings":["Department of Microbiology and Immunology, Bio21 Institute and Peter Doherty Institute, The University of Melbourne, Melbourne, Australia","School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia"],"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Bio21 Institute and Peter Doherty Institute, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I165779595"]},{"raw_affiliation_string":"School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038441670","display_name":"Dionne C. Argyropoulos","orcid":"https://orcid.org/0000-0002-8068-0215"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Dionne C. Argyropoulos","raw_affiliation_strings":["Department of Microbiology and Immunology, Bio21 Institute and Peter Doherty Institute, The University of Melbourne, Melbourne, Australia","School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia"],"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Bio21 Institute and Peter Doherty Institute, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I165779595"]},{"raw_affiliation_string":"School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043863435","display_name":"Mun Hua Tan","orcid":"https://orcid.org/0000-0003-3396-8213"},"institutions":[{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I165779595","display_name":"University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Mun Hua Tan","raw_affiliation_strings":["Department of Microbiology and Immunology, Bio21 Institute and Peter Doherty Institute, The University of Melbourne, Melbourne, Australia","School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia"],"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Bio21 Institute and Peter Doherty Institute, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I165779595"]},{"raw_affiliation_string":"School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035940305","display_name":"Anita Ghansah","orcid":"https://orcid.org/0000-0003-4639-1249"},"institutions":[{"id":"https://openalex.org/I4210091910","display_name":"Noguchi Memorial Institute for Medical Research","ror":"https://ror.org/00f1qr933","country_code":"GH","type":"nonprofit","lineage":["https://openalex.org/I138690464","https://openalex.org/I4210091910"]},{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]}],"countries":["GH"],"is_corresponding":true,"raw_author_name":"Anita Ghansah","raw_affiliation_strings":["Department of Parasitology, Noguchi Memorial Institute for Medical Research, College of Health Science, University of Ghana, Legon, Ghana"],"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Noguchi Memorial Institute for Medical Research, College of Health Science, University of Ghana, Legon, Ghana","institution_ids":["https://openalex.org/I4210091910","https://openalex.org/I138690464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048534219","display_name":"Karen P. Day","orcid":"https://orcid.org/0000-0002-6115-6135"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Karen P. Day","raw_affiliation_strings":["Department of Microbiology and Immunology, Bio21 Institute and Peter Doherty Institute, The University of Melbourne, Melbourne, Australia","School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia"],"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Bio21 Institute and Peter Doherty Institute, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I165779595"]},{"raw_affiliation_string":"School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059708665","display_name":"Mercedes Pascual","orcid":"https://orcid.org/0000-0003-3575-7233"},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I1308548392","display_name":"Santa Fe Institute","ror":"https://ror.org/01arysc35","country_code":"US","type":"funder","lineage":["https://openalex.org/I1308548392"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mercedes Pascual","raw_affiliation_strings":["Department of Ecology and Evolution, The University of Chicago, Chicago, Illinois, United States of America","Santa Fe Institute, Santa Fe, New Mexico, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Ecology and Evolution, The University of Chicago, Chicago, Illinois, United States of America","institution_ids":["https://openalex.org/I40347166"]},{"raw_affiliation_string":"Santa Fe Institute, Santa Fe, New Mexico, United States of America","institution_ids":["https://openalex.org/I1308548392"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5015206026","https://openalex.org/A5028427304","https://openalex.org/A5035940305","https://openalex.org/A5038441670","https://openalex.org/A5043863435","https://openalex.org/A5047487804","https://openalex.org/A5048534219","https://openalex.org/A5059708665","https://openalex.org/A5100664084"],"corresponding_institution_ids":["https://openalex.org/I1308548392","https://openalex.org/I138690464","https://openalex.org/I165779595","https://openalex.org/I219193219","https://openalex.org/I40347166","https://openalex.org/I4210091910","https://openalex.org/I4210105123","https://openalex.org/I55769427"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":8.7896,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.98261591,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"19","issue":"1","first_page":"e1010816","last_page":"e1010816"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9889000058174133,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":0.98089998960495,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.7400883436203003},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.47714778780937195},{"id":"https://openalex.org/keywords/malaria","display_name":"Malaria","score":0.460924357175827},{"id":"https://openalex.org/keywords/plasmodium","display_name":"Plasmodium (life cycle)","score":0.4213292896747589},{"id":"https://openalex.org/keywords/zoology","display_name":"Zoology","score":0.3303045332431793},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.3257991075515747},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.14980128407478333},{"id":"https://openalex.org/keywords/parasite-hosting","display_name":"Parasite hosting","score":0.11704105138778687}],"concepts":[{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.7400883436203003},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47714778780937195},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.460924357175827},{"id":"https://openalex.org/C2778675580","wikidata":"https://www.wikidata.org/wiki/Q614956","display_name":"Plasmodium (life cycle)","level":3,"score":0.4213292896747589},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.3303045332431793},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.3257991075515747},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.14980128407478333},{"id":"https://openalex.org/C71928629","wikidata":"https://www.wikidata.org/wiki/Q804206","display_name":"Parasite hosting","level":2,"score":0.11704105138778687},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000953","descriptor_name":"Antigens, Protozoan","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000953","descriptor_name":"Antigens, Protozoan","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000953","descriptor_name":"Antigens, Protozoan","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000953","descriptor_name":"Antigens, Protozoan","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":true},{"descriptor_ui":"D018895","descriptor_name":"Microsatellite Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018895","descriptor_name":"Microsatellite Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018895","descriptor_name":"Microsatellite Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018895","descriptor_name":"Microsatellite Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pcbi.1010816","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010816","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:36595546","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36595546","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:9838855","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9838855","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9838855/pdf/pcbi.1010816.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:uchicago.tind.io:6334","is_oa":true,"landing_page_url":"http://knowledge.uchicago.edu/record/6334","pdf_url":null,"source":{"id":"https://openalex.org/S4306402460","display_name":"Knowledge@UChicago (University of Chicago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I40347166","host_organization_name":"University of Chicago","host_organization_lineage":["https://openalex.org/I40347166"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://knowledge.uchicago.edu/record/6334","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:a33ec2008d3f44c9ae63cf1d9dc94233","is_oa":true,"landing_page_url":"https://doaj.org/article/a33ec2008d3f44c9ae63cf1d9dc94233","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 19, Iss 1, p e1010816 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1010816","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010816","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8100000023841858,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G3285692336","display_name":null,"funder_award_id":"R01-TW009670","funder_id":"https://openalex.org/F4320337356","funder_display_name":"Fogarty International Center"},{"id":"https://openalex.org/G3626119005","display_name":null,"funder_award_id":"Fogarty","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4516578739","display_name":null,"funder_award_id":"R01-AI149779","funder_id":"https://openalex.org/F4320337356","funder_display_name":"Fogarty International Center"},{"id":"https://openalex.org/G5653438523","display_name":null,"funder_award_id":"R01-AI149779","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6755165505","display_name":null,"funder_award_id":"award","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G793955707","display_name":null,"funder_award_id":"R01-TW009670","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320309626","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332299","display_name":"National Institute of Food and Agriculture","ror":"https://ror.org/05qx3fv49"},{"id":"https://openalex.org/F4320337356","display_name":"Fogarty International Center","ror":"https://ror.org/02xey9a22"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":73,"referenced_works":["https://openalex.org/W33405318","https://openalex.org/W1516752631","https://openalex.org/W1662927876","https://openalex.org/W1940072256","https://openalex.org/W1969538464","https://openalex.org/W1987805675","https://openalex.org/W1990276564","https://openalex.org/W1993441829","https://openalex.org/W1997476591","https://openalex.org/W1999417874","https://openalex.org/W2001488223","https://openalex.org/W2002398458","https://openalex.org/W2010795697","https://openalex.org/W2013399821","https://openalex.org/W2019851585","https://openalex.org/W2020489688","https://openalex.org/W2029582065","https://openalex.org/W2035054548","https://openalex.org/W2042321087","https://openalex.org/W2046179807","https://openalex.org/W2049700891","https://openalex.org/W2051476615","https://openalex.org/W2058543649","https://openalex.org/W2062069878","https://openalex.org/W2072975902","https://openalex.org/W2078734278","https://openalex.org/W2084104232","https://openalex.org/W2087628191","https://openalex.org/W2090438722","https://openalex.org/W2091524791","https://openalex.org/W2092543202","https://openalex.org/W2096290393","https://openalex.org/W2101320218","https://openalex.org/W2103171514","https://openalex.org/W2110368176","https://openalex.org/W2112159173","https://openalex.org/W2112163870","https://openalex.org/W2112428133","https://openalex.org/W2117530396","https://openalex.org/W2120873510","https://openalex.org/W2127848106","https://openalex.org/W2131962601","https://openalex.org/W2146952198","https://openalex.org/W2148686938","https://openalex.org/W2149050959","https://openalex.org/W2155135480","https://openalex.org/W2155925360","https://openalex.org/W2169819189","https://openalex.org/W2170874271","https://openalex.org/W2171719289","https://openalex.org/W2266475816","https://openalex.org/W2402608199","https://openalex.org/W2581965723","https://openalex.org/W2582743722","https://openalex.org/W2610356758","https://openalex.org/W2611961786","https://openalex.org/W2753961871","https://openalex.org/W2784054171","https://openalex.org/W2949790187","https://openalex.org/W2950972892","https://openalex.org/W2951466600","https://openalex.org/W2951479370","https://openalex.org/W2952962132","https://openalex.org/W2987951717","https://openalex.org/W3133088939","https://openalex.org/W3164435226","https://openalex.org/W4200110643","https://openalex.org/W4210397424","https://openalex.org/W4210622960","https://openalex.org/W4231311503","https://openalex.org/W4280494412","https://openalex.org/W4362588742","https://openalex.org/W7075737834"],"related_works":["https://openalex.org/W4387010470","https://openalex.org/W2084516783","https://openalex.org/W3215554334","https://openalex.org/W4378840690","https://openalex.org/W2043005394","https://openalex.org/W4389493532","https://openalex.org/W2120900442","https://openalex.org/W2912700465","https://openalex.org/W2000120861","https://openalex.org/W2338515619"],"abstract_inverted_index":{"At":[0],"a":[1,41,55,104,164],"time":[2],"when":[3],"effective":[4],"tools":[5],"for":[6,48,57,220,230,293],"monitoring":[7,294],"malaria":[8,50,154,271],"control":[9],"and":[10,98,112,129,177,222,245,265,286],"eradication":[11],"efforts":[12],"are":[13,175],"crucial,":[14],"the":[15,33,100,110,117,122,139,142,275,295],"increasing":[16],"availability":[17],"of":[18,28,35,116,141,163,226,261,297],"molecular":[19,82],"data":[20],"motivates":[21],"their":[22],"application":[23],"to":[24,73,279],"epidemiology.":[25],"The":[26],"multiplicity":[27],"infection":[29],"(MOI),":[30],"defined":[31],"as":[32],"number":[34],"genetically":[36],"distinct":[37,181],"parasite":[38],"strains":[39],"co-infecting":[40],"host,":[42],"is":[43,89,103,130,200,243,290],"one":[44],"key":[45],"epidemiological":[46],"parameter":[47],"evaluating":[49],"interventions.":[51],"Estimating":[52],"MOI":[53,143,241,254,281],"remains":[54],"challenge":[56],"high-transmission":[58],"settings":[59],"where":[60,197],"individuals":[61],"typically":[62],"carry":[63],"multiple":[64],"co-occurring":[65],"infections.":[66],"Several":[67],"quantitative":[68],"approaches":[69,149,174],"have":[70],"been":[71],"developed":[72,166],"estimate":[74,280],"MOI,":[75,188,214],"including":[76],"two":[77,148],"cost-effective":[78],"ones":[79],"relying":[80],"on":[81,91,109,283],"data:":[83],"i)":[84],"THE":[85,208,231],"REAL":[86,209,232],"McCOIL":[87,210,233],"method":[88,102],"based":[90,282],"putatively":[92],"neutral":[93],"single":[94],"nucleotide":[95],"polymorphism":[96],"loci,":[97],"ii)":[99],"varcoding":[101,185],"fingerprinting":[105],"approach":[106,278],"that":[107,172,235,246],"relies":[108],"diversity":[111],"limited":[113,202],"repertoire":[114,198],"overlap":[115,199],"var":[118],"multigene":[119],"family":[120],"encoding":[121],"major":[123],"Plasmodium":[124],"falciparum":[125,153],"blood-stage":[126],"antigen":[127],"PfEMP1":[128],"therefore":[131],"under":[132,156,194],"selection.":[133,205],"In":[134,206],"this":[135],"study,":[136],"we":[137],"assess":[138],"robustness":[140],"estimates":[144,219],"generated":[145],"with":[146],"these":[147,173],"by":[150],"simulating":[151],"P.":[152],"dynamics":[155],"three":[157],"transmission":[158,182,196,227,288],"conditions":[159],"using":[160],"an":[161,236,250],"extension":[162],"previously":[165],"stochastic":[167],"agent-based":[168],"model.":[169],"We":[170],"demonstrate":[171],"complementary":[176],"best":[178],"considered":[179],"across":[180],"intensities.":[183],"While":[184],"can":[186,256],"underestimate":[187],"it":[189],"allows":[190],"robust":[191],"estimation,":[192],"especially":[193],"high":[195,240,248],"extremely":[201],"from":[203,258],"frequency-dependent":[204],"contrast,":[207],"often":[211],"considerably":[212],"overestimates":[213],"but":[215],"still":[216],"provides":[217],"reasonable":[218,252],"low":[221],"moderate":[223],"transmission.":[224],"Regardless":[225],"intensity,":[228],"results":[229],"indicate":[234],"inaccurate":[237],"tail":[238],"at":[239,247],"values":[242],"generated,":[244],"transmission,":[249],"apparently":[251],"estimated":[253],"distribution":[255],"arise":[257],"some":[259],"degree":[260],"compensation":[262],"between":[263],"overestimation":[264],"underestimation.":[266],"As":[267],"many":[268],"countries":[269],"pursue":[270],"elimination":[272],"targets,":[273],"defining":[274],"most":[276],"suitable":[277],"sample":[284],"size":[285],"local":[287],"intensity":[289],"highly":[291],"recommended":[292],"impact":[296],"intervention":[298],"programs.":[299]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":10}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}