{"id":"https://openalex.org/W4311582517","doi":"https://doi.org/10.1371/journal.pcbi.1010681","title":"Comparing T cell receptor repertoires using optimal transport","display_name":"Comparing T cell receptor repertoires using optimal transport","publication_year":2022,"publication_date":"2022-12-07","ids":{"openalex":"https://openalex.org/W4311582517","doi":"https://doi.org/10.1371/journal.pcbi.1010681","pmid":"https://pubmed.ncbi.nlm.nih.gov/36476997"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1010681","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010681","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1371/journal.pcbi.1010681","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089176448","display_name":"Branden J Olson","orcid":"https://orcid.org/0000-0003-1951-8822"},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Branden J. Olson","raw_affiliation_strings":["Department of Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America","Department of Statistics, University of Washington, Seattle, Washington, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Department of Statistics, University of Washington, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002608041","display_name":"Stefan Schattgen","orcid":"https://orcid.org/0000-0002-6860-5079"},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stefan A. Schattgen","raw_affiliation_strings":["Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America","institution_ids":["https://openalex.org/I1313298211"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005724506","display_name":"Paul G. Thomas","orcid":"https://orcid.org/0000-0001-7955-0256"},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul G. Thomas","raw_affiliation_strings":["Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America","institution_ids":["https://openalex.org/I1313298211"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067744380","display_name":"Philip Bradley","orcid":"https://orcid.org/0000-0002-0224-6464"},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Philip Bradley","raw_affiliation_strings":["Department of Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America","Institute for Protein Design, Department of Biochemistry, University of Washington, Seattle, Washington, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Institute for Protein Design, Department of Biochemistry, University of Washington, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084752404","display_name":"F. A. Matsen","orcid":"https://orcid.org/0000-0003-0607-6025"},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Frederick A. Matsen IV","raw_affiliation_strings":["Department of Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America","Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America","Department of Statistics, University of Washington, Seattle, Washington, United States of America","Howard Hughes Medical Institute, Seattle, Washington, United States of America"],"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I4210089486"]},{"raw_affiliation_string":"Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Statistics, University of Washington, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, Seattle, Washington, United States of America","institution_ids":["https://openalex.org/I1344073410"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5067744380","https://openalex.org/A5084752404"],"corresponding_institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I201448701","https://openalex.org/I4210089486"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":0.5091,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.61960698,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"18","issue":"12","first_page":"e1010681","last_page":"e1010681"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/t-cell-receptor","display_name":"T-cell receptor","score":0.803181529045105},{"id":"https://openalex.org/keywords/repertoire","display_name":"Repertoire","score":0.5996273159980774},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5904434323310852},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5761556625366211},{"id":"https://openalex.org/keywords/metric","display_name":"Metric (unit)","score":0.5461767911911011},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.49918150901794434},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.43773573637008667},{"id":"https://openalex.org/keywords/nonparametric-statistics","display_name":"Nonparametric statistics","score":0.4122542142868042},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3298462927341461},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.25861185789108276},{"id":"https://openalex.org/keywords/t-cell","display_name":"T cell","score":0.2051655650138855},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.14412567019462585},{"id":"https://openalex.org/keywords/econometrics","display_name":"Econometrics","score":0.10224694013595581},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.09293672442436218}],"concepts":[{"id":"https://openalex.org/C19317047","wikidata":"https://www.wikidata.org/wiki/Q412037","display_name":"T-cell receptor","level":4,"score":0.803181529045105},{"id":"https://openalex.org/C2778473898","wikidata":"https://www.wikidata.org/wiki/Q2145110","display_name":"Repertoire","level":2,"score":0.5996273159980774},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5904434323310852},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5761556625366211},{"id":"https://openalex.org/C176217482","wikidata":"https://www.wikidata.org/wiki/Q860554","display_name":"Metric (unit)","level":2,"score":0.5461767911911011},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.49918150901794434},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.43773573637008667},{"id":"https://openalex.org/C102366305","wikidata":"https://www.wikidata.org/wiki/Q1097688","display_name":"Nonparametric statistics","level":2,"score":0.4122542142868042},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3298462927341461},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.25861185789108276},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.2051655650138855},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14412567019462585},{"id":"https://openalex.org/C149782125","wikidata":"https://www.wikidata.org/wiki/Q160039","display_name":"Econometrics","level":1,"score":0.10224694013595581},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09293672442436218},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pcbi.1010681","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010681","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:36476997","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36476997","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:RePEc:plo:pcbi00:1010681","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1010681","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:07e08b08cdfd43c5b68f7ac983c2b188","is_oa":true,"landing_page_url":"https://doaj.org/article/07e08b08cdfd43c5b68f7ac983c2b188","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 18, Iss 12, p e1010681 (2022)","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:f57ce3b08e2048eea1c4e7c612b87c51","is_oa":true,"landing_page_url":"https://doaj.org/article/f57ce3b08e2048eea1c4e7c612b87c51","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 18, Iss 12 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9728925","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9728925","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1010681","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010681","pdf_url":null,"source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1171340397","display_name":null,"funder_award_id":"U01 AI150747","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1181615728","display_name":null,"funder_award_id":"U19 AI117891","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1737146978","display_name":null,"funder_award_id":"AI146028","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3459986961","display_name":null,"funder_award_id":"117891","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3591773756","display_name":null,"funder_award_id":"AI117891","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3793080050","display_name":null,"funder_award_id":"GM141457","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G395005526","display_name":null,"funder_award_id":"R01 AI146028, U19 AI117891","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4801706982","display_name":null,"funder_award_id":"R01 AI146028","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5908696684","display_name":null,"funder_award_id":"R35 GM141457","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7670087334","display_name":null,"funder_award_id":"R35 GM141457, R01 AI146028","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8148421309","display_name":null,"funder_award_id":"R01 AI121832","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8253867094","display_name":null,"funder_award_id":"R01 AI136514","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8299881407","display_name":null,"funder_award_id":"AI136514","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8339084506","display_name":null,"funder_award_id":"AI121832","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"},{"id":"https://openalex.org/F4320306164","display_name":"Simons Foundation","ror":"https://ror.org/01cmst727"},{"id":"https://openalex.org/F4320313598","display_name":"American Lebanese Syrian Associated Charities","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W763239503","https://openalex.org/W1535793628","https://openalex.org/W1607133945","https://openalex.org/W1643112662","https://openalex.org/W1750023785","https://openalex.org/W1786753252","https://openalex.org/W2010295342","https://openalex.org/W2042096299","https://openalex.org/W2051241958","https://openalex.org/W2108588173","https://openalex.org/W2114569569","https://openalex.org/W2127774996","https://openalex.org/W2132983397","https://openalex.org/W2143210482","https://openalex.org/W2151831732","https://openalex.org/W2525754298","https://openalex.org/W2565989705","https://openalex.org/W2570205435","https://openalex.org/W2593304336","https://openalex.org/W2670890989","https://openalex.org/W2671261300","https://openalex.org/W2748268306","https://openalex.org/W2751843937","https://openalex.org/W2752126733","https://openalex.org/W2769564164","https://openalex.org/W2797380951","https://openalex.org/W2894849296","https://openalex.org/W2912192115","https://openalex.org/W2949975396","https://openalex.org/W2971575097","https://openalex.org/W2981941208","https://openalex.org/W2990308980","https://openalex.org/W2997460715","https://openalex.org/W3019459038","https://openalex.org/W3020331344","https://openalex.org/W3089488427","https://openalex.org/W3120048001","https://openalex.org/W3141959661","https://openalex.org/W3196175936","https://openalex.org/W3216334900","https://openalex.org/W3217170401","https://openalex.org/W4226199741","https://openalex.org/W4287245321","https://openalex.org/W4292634236","https://openalex.org/W6795007937"],"related_works":["https://openalex.org/W3120300186","https://openalex.org/W2084831119","https://openalex.org/W4255048859","https://openalex.org/W4378635687","https://openalex.org/W2060496539","https://openalex.org/W4280506224","https://openalex.org/W2018330851","https://openalex.org/W2143290387","https://openalex.org/W3201606428","https://openalex.org/W3087255036"],"abstract_inverted_index":{"The":[0],"complexity":[1],"of":[2,19,28],"entire":[3],"T":[4],"cell":[5],"receptor":[6],"(TCR)":[7],"repertoires":[8,78],"makes":[9],"their":[10],"comparison":[11,22,48],"a":[12,25,43,71,84,91,127],"difficult":[13],"but":[14],"important":[15],"task.":[16],"Current":[17],"methods":[18,41,102,121],"TCR":[20,77,110],"repertoire":[21],"can":[23],"incur":[24],"high":[26],"loss":[27],"distributional":[29],"information":[30],"by":[31],"considering":[32],"overly":[33],"simplistic":[34],"sequence-":[35],"or":[36,52],"repertoire-level":[37],"characteristics.":[38],"Optimal":[39],"transport":[40,88],"form":[42],"suitable":[44],"approach":[45,73],"for":[46,112],"such":[47],"given":[49],"some":[50],"distance":[51,93],"metric":[53],"between":[54,94,106],"values":[55],"in":[56],"the":[57,81],"sample":[58],"space,":[59],"with":[60,118],"appealing":[61],"theoretical":[62],"and":[63,90,116,126],"computational":[64],"properties.":[65],"In":[66],"this":[67],"paper":[68],"we":[69],"introduce":[70],"nonparametric":[72],"to":[74],"comparing":[75],"empirical":[76],"that":[79,100],"applies":[80],"Sinkhorn":[82],"distance,":[83],"fast,":[85],"contemporary":[86],"optimal":[87],"method,":[89],"recently-created":[92],"TCRs":[95],"called":[96],"TCRdist.":[97],"We":[98],"show":[99],"our":[101],"identify":[103],"meaningful":[104],"differences":[105],"samples":[107],"from":[108],"distinct":[109],"distributions":[111],"several":[113],"case":[114],"studies,":[115],"compete":[117],"more":[119],"complicated":[120],"despite":[122],"minimal":[123],"modeling":[124],"assumptions":[125],"simpler":[128],"pipeline.":[129]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2}],"updated_date":"2026-04-13T07:58:08.660418","created_date":"2025-10-10T00:00:00"}