{"id":"https://openalex.org/W4282053111","doi":"https://doi.org/10.1371/journal.pcbi.1010138","title":"Analysing and meta-analysing time-series data of microbial growth and gene expression from plate readers","display_name":"Analysing and meta-analysing time-series data of microbial growth and gene expression from plate readers","publication_year":2022,"publication_date":"2022-05-26","ids":{"openalex":"https://openalex.org/W4282053111","doi":"https://doi.org/10.1371/journal.pcbi.1010138","pmid":"https://pubmed.ncbi.nlm.nih.gov/35617352"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1010138","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010138","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010138&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010138&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052653700","display_name":"Luis F. Monta\u00f1o-Gutierrez","orcid":"https://orcid.org/0000-0003-2383-1483"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Luis Fernando Monta\u00f1o-Gutierrez","raw_affiliation_strings":["School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0003-2383-1483","affiliations":[{"raw_affiliation_string":"School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048857390","display_name":"Nahuel Moreno","orcid":"https://orcid.org/0000-0002-1631-8430"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nahuel Manzanaro Moreno","raw_affiliation_strings":["School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-1631-8430","affiliations":[{"raw_affiliation_string":"School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088284329","display_name":"Iseabail Farquhar","orcid":"https://orcid.org/0000-0002-8108-3498"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Iseabail L. Farquhar","raw_affiliation_strings":["School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-8108-3498","affiliations":[{"raw_affiliation_string":"School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038811208","display_name":"Yu Huo","orcid":"https://orcid.org/0000-0002-7427-3007"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Yu Huo","raw_affiliation_strings":["School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-7427-3007","affiliations":[{"raw_affiliation_string":"School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083852374","display_name":"Lucia Bandiera","orcid":"https://orcid.org/0000-0002-8811-4816"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lucia Bandiera","raw_affiliation_strings":["School of Engineering, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-8811-4816","affiliations":[{"raw_affiliation_string":"School of Engineering, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053098071","display_name":"Peter S. Swain","orcid":"https://orcid.org/0000-0001-7489-8587"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Peter S. Swain","raw_affiliation_strings":["School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0001-7489-8587","affiliations":[{"raw_affiliation_string":"School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5053098071"],"corresponding_institution_ids":["https://openalex.org/I98677209"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":1.2151,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.77835175,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"18","issue":"5","first_page":"e1010138","last_page":"e1010138"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5599126219749451},{"id":"https://openalex.org/keywords/raffinose","display_name":"Raffinose","score":0.5343149900436401},{"id":"https://openalex.org/keywords/repressor","display_name":"Repressor","score":0.5281515121459961},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.4503258764743805},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4404739737510681},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.44035622477531433},{"id":"https://openalex.org/keywords/yeast","display_name":"Yeast","score":0.41836318373680115},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.4169039726257324},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.37377604842185974},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3305304944515228}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5599126219749451},{"id":"https://openalex.org/C2779998883","wikidata":"https://www.wikidata.org/wiki/Q410005","display_name":"Raffinose","level":3,"score":0.5343149900436401},{"id":"https://openalex.org/C158448853","wikidata":"https://www.wikidata.org/wiki/Q425218","display_name":"Repressor","level":4,"score":0.5281515121459961},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4503258764743805},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4404739737510681},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.44035622477531433},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.41836318373680115},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.4169039726257324},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.37377604842185974},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3305304944515228},{"id":"https://openalex.org/C2778597767","wikidata":"https://www.wikidata.org/wiki/Q4027534","display_name":"Sucrose","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009004","descriptor_name":"Monosaccharide Transport Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009004","descriptor_name":"Monosaccharide Transport Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009004","descriptor_name":"Monosaccharide Transport Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011887","descriptor_name":"Raffinose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011887","descriptor_name":"Raffinose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011887","descriptor_name":"Raffinose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pcbi.1010138","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010138","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010138&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:35617352","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35617352","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:pure.ed.ac.uk:openaire/bf214942-4207-4507-a04b-bf3d8809156c","is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/en/publications/bf214942-4207-4507-a04b-bf3d8809156c","pdf_url":null,"source":{"id":"https://openalex.org/S4406922455","display_name":"Edinburgh Research Explorer","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Montano Gutierrez, L F, Manzanaro Moreno, N, Farquhar, I, Huo, Y, Bandiera, L & Swain, P S 2022, 'Analysing and meta-analysing time-series data of microbial growth and gene expression from plate readers', PLoS Computational Biology, vol. 18, no. 5, e1010138. https://doi.org/10.1371/journal.pcbi.1010138","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:RePEc:plo:pcbi00:1010138","is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1010138","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:a9dcc4536a594b20a407fec44e4d4f0d","is_oa":true,"landing_page_url":"https://doaj.org/article/a9dcc4536a594b20a407fec44e4d4f0d","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 18, Iss 5, p e1010138 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9176753","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9176753","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:pure.ed.ac.uk:publications/bf214942-4207-4507-a04b-bf3d8809156c","is_oa":false,"landing_page_url":"https://swainlab.bio.ed.ac.uk/software/omniplate","pdf_url":null,"source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1010138","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010138","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010138&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Responsible consumption and production","id":"https://metadata.un.org/sdg/12","score":0.46000000834465027}],"awards":[{"id":"https://openalex.org/G31189663","display_name":null,"funder_award_id":"EP/P017134/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G3964709221","display_name":null,"funder_award_id":"RPG-2018-004","funder_id":"https://openalex.org/F4320319993","funder_display_name":"Leverhulme Trust"},{"id":"https://openalex.org/G6350605344","display_name":"Understanding the regulation of glucose sensing and transport in budding yeast using dynamic inputs","funder_award_id":"BB/R001359/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G6496890878","display_name":null,"funder_award_id":"BB/R001359/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320307874","display_name":"Wellcome","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320319993","display_name":"Leverhulme Trust","ror":"https://ror.org/012mzw131"},{"id":"https://openalex.org/F4320331788","display_name":"Darwin Trust of Edinburgh","ror":null},{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4282053111.pdf"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W569634410","https://openalex.org/W1964268317","https://openalex.org/W1988608160","https://openalex.org/W1996119276","https://openalex.org/W1996264210","https://openalex.org/W2017784165","https://openalex.org/W2038540528","https://openalex.org/W2042493870","https://openalex.org/W2048094578","https://openalex.org/W2049194379","https://openalex.org/W2054427850","https://openalex.org/W2060981193","https://openalex.org/W2084338561","https://openalex.org/W2095928146","https://openalex.org/W2099685366","https://openalex.org/W2100485294","https://openalex.org/W2100507715","https://openalex.org/W2101762601","https://openalex.org/W2117848006","https://openalex.org/W2123425265","https://openalex.org/W2129151536","https://openalex.org/W2130665506","https://openalex.org/W2137402060","https://openalex.org/W2143140464","https://openalex.org/W2144683622","https://openalex.org/W2145185052","https://openalex.org/W2146546288","https://openalex.org/W2146984904","https://openalex.org/W2150331704","https://openalex.org/W2151622042","https://openalex.org/W2160014215","https://openalex.org/W2161942543","https://openalex.org/W2167138922","https://openalex.org/W2168317391","https://openalex.org/W2295815045","https://openalex.org/W2339485220","https://openalex.org/W2389935477","https://openalex.org/W2519870106","https://openalex.org/W2561548155","https://openalex.org/W2614283331","https://openalex.org/W2775383981","https://openalex.org/W2952668961","https://openalex.org/W2953509182","https://openalex.org/W3081709137","https://openalex.org/W3125293018","https://openalex.org/W4211049957","https://openalex.org/W4224785208"],"related_works":["https://openalex.org/W2131585994","https://openalex.org/W2073787639","https://openalex.org/W2145883500","https://openalex.org/W1544270252","https://openalex.org/W2028107853","https://openalex.org/W1982584572","https://openalex.org/W4210617669","https://openalex.org/W4232406862","https://openalex.org/W2397070560","https://openalex.org/W4402640375"],"abstract_inverted_index":{"Responding":[0],"to":[1,24,115],"change":[2],"is":[3,131,215],"a":[4,20,44,59,132,216],"fundamental":[5],"property":[6],"of":[7,37,77,88,104,109,123,155],"life,":[8],"making":[9],"time-series":[10,225],"data":[11,41,226],"invaluable":[12],"in":[13,82,126,227],"biology.":[14],"For":[15],"microbes,":[16],"plate":[17],"readers":[18],"are":[19,150,170,197],"popular,":[21],"convenient":[22,133],"means":[23],"measure":[25,116],"growth":[26,69,122,138],"and":[27,53,64,71,85,106,166,181,191],"also":[28],"gene":[29],"expression":[30],"using":[31],"fluorescent":[32,141],"reporters.":[33],"Nevertheless,":[34],"the":[35,39,96,102,107,110,117,121,153,156,164,175,182,187,193,201,207,221],"difficulties":[36],"analysing":[38],"resulting":[40],"can":[42],"be":[43],"bottleneck,":[45],"particularly":[46],"when":[47],"combining":[48],"measurements":[49],"from":[50],"different":[51,83],"wells":[52],"plates.":[54,90],"Here":[55],"we":[56,143],"present":[57],"omniplate,":[58],"Python":[60],"module":[61],"that":[62,129,213],"corrects":[63,93],"normalises":[65],"plate-reader":[66],"data,":[67],"estimates":[68],"rates":[70],"fluorescence":[72],"per":[73],"cell":[74],"as":[75],"functions":[76],"time,":[78],"calculates":[79],"errors,":[80],"exports":[81],"formats,":[84],"enables":[86],"meta-analysis":[87],"multiple":[89],"The":[91],"software":[92],"for":[94,120,136,219],"autofluorescence,":[95],"optical":[97],"density's":[98],"non-linear":[99],"dependence":[100],"on":[101],"number":[103],"cells,":[105],"effects":[108],"media.":[111],"We":[112,210],"use":[113],"omniplate":[114,214],"Monod":[118],"relationship":[119],"budding":[124],"yeast":[125],"raffinose,":[127],"showing":[128],"raffinose":[130],"carbon":[134],"source":[135],"controlling":[137],"rates.":[139],"Using":[140],"tagging,":[142],"study":[144],"yeast's":[145],"glucose":[146,178],"transport.":[147],"Our":[148],"results":[149],"consistent":[151],"with":[152],"regulation":[154],"hexose":[157],"transporter":[158],"(HXT)":[159],"genes":[160],"being":[161],"approximately":[162],"bipartite:":[163],"medium":[165],"high":[167,176],"affinity":[168,177,195,203],"transporters":[169,196],"predominately":[171,198],"regulated":[172,199],"by":[173,200,224],"both":[174],"sensor":[179,204],"Snf3":[180],"kinase":[183],"complex":[184],"SNF1":[185],"via":[186,206],"repressors":[188],"Mth1,":[189],"Mig1,":[190],"Mig2;":[192],"low":[194,202],"Rgt2":[205],"co-repressor":[208],"Std1.":[209],"thus":[211],"demonstrate":[212],"powerful":[217],"tool":[218],"exploiting":[220],"advantages":[222],"offered":[223],"revealing":[228],"biological":[229],"regulation.":[230]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4}],"updated_date":"2026-01-17T23:10:49.606395","created_date":"2025-10-10T00:00:00"}