{"id":"https://openalex.org/W4309231816","doi":"https://doi.org/10.1371/journal.pcbi.1010111","title":"A neurocomputational theory of action regulation predicts motor behavior in neurotypical individuals and patients with Parkinson\u2019s disease","display_name":"A neurocomputational theory of action regulation predicts motor behavior in neurotypical individuals and patients with Parkinson\u2019s disease","publication_year":2022,"publication_date":"2022-11-17","ids":{"openalex":"https://openalex.org/W4309231816","doi":"https://doi.org/10.1371/journal.pcbi.1010111","pmid":"https://pubmed.ncbi.nlm.nih.gov/36395336"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1010111","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010111","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010111&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010111&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111041395","display_name":"Shan Zhong","orcid":null},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shan Zhong","raw_affiliation_strings":["Neuroscience graduate program, University of California Riverside, Riverside, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroscience graduate program, University of California Riverside, Riverside, California, United States of America","institution_ids":["https://openalex.org/I103635307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019112271","display_name":"Jeong Woo Choi","orcid":"https://orcid.org/0000-0001-5824-8859"},"institutions":[{"id":"https://openalex.org/I4210096815","display_name":"Southwestern Medical Center","ror":"https://ror.org/00t9vx427","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210096815"]},{"id":"https://openalex.org/I4210157890","display_name":"Neurological Surgery","ror":"https://ror.org/04r0gp612","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210157890"]},{"id":"https://openalex.org/I4388891891","display_name":"Southwestern Medical Center","ror":"https://ror.org/05d80e146","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4388891891"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeong Woo Choi","raw_affiliation_strings":["Department of Neurological Surgery, UT Southwestern Medical Center, Dallas, Texas, United States of America"],"raw_orcid":"https://orcid.org/0000-0001-5824-8859","affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, UT Southwestern Medical Center, Dallas, Texas, United States of America","institution_ids":["https://openalex.org/I4210157890","https://openalex.org/I867280407","https://openalex.org/I4210096815","https://openalex.org/I4388891891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089658821","display_name":"Nadia G. Hashoush","orcid":null},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nadia G. Hashoush","raw_affiliation_strings":["David Geffen Sch. of Med., University of California Los Angeles, Los Angeles, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"David Geffen Sch. of Med., University of California Los Angeles, Los Angeles, California, United States of America","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004267696","display_name":"Diana Babayan","orcid":"https://orcid.org/0000-0001-5994-5656"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diana Babayan","raw_affiliation_strings":["David Geffen Sch. of Med., University of California Los Angeles, Los Angeles, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"David Geffen Sch. of Med., University of California Los Angeles, Los Angeles, California, United States of America","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065103315","display_name":"Mahsa Malekmohammadi","orcid":"https://orcid.org/0000-0002-2395-7134"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mahsa Malekmohammadi","raw_affiliation_strings":["David Geffen Sch. of Med., University of California Los Angeles, Los Angeles, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"David Geffen Sch. of Med., University of California Los Angeles, Los Angeles, California, United States of America","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004627402","display_name":"Nader Pouratian","orcid":"https://orcid.org/0000-0002-0426-3241"},"institutions":[{"id":"https://openalex.org/I4210096815","display_name":"Southwestern Medical Center","ror":"https://ror.org/00t9vx427","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210096815"]},{"id":"https://openalex.org/I4210157890","display_name":"Neurological Surgery","ror":"https://ror.org/04r0gp612","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210157890"]},{"id":"https://openalex.org/I4388891891","display_name":"Southwestern Medical Center","ror":"https://ror.org/05d80e146","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4388891891"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nader Pouratian","raw_affiliation_strings":["Department of Neurological Surgery, UT Southwestern Medical Center, Dallas, Texas, United States of America"],"raw_orcid":"https://orcid.org/0000-0002-0426-3241","affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, UT Southwestern Medical Center, Dallas, Texas, United States of America","institution_ids":["https://openalex.org/I4210157890","https://openalex.org/I867280407","https://openalex.org/I4210096815","https://openalex.org/I4388891891"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111902837","display_name":"Vassilios Christopoulos","orcid":null},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Vassilios Christopoulos","raw_affiliation_strings":["Department of Bioengineering, University of California Riverside, Riverside, California, United States of America","Neuroscience graduate program, University of California Riverside, Riverside, California, United States of America"],"raw_orcid":"https://orcid.org/0000-0002-0541-8700","affiliations":[{"raw_affiliation_string":"Department of Bioengineering, University of California Riverside, Riverside, California, United States of America","institution_ids":["https://openalex.org/I103635307"]},{"raw_affiliation_string":"Neuroscience graduate program, University of California Riverside, Riverside, California, United States of America","institution_ids":["https://openalex.org/I103635307"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5004627402","https://openalex.org/A5111902837"],"corresponding_institution_ids":["https://openalex.org/I103635307","https://openalex.org/I4210096815","https://openalex.org/I4210157890","https://openalex.org/I4388891891","https://openalex.org/I867280407"],"apc_list":{"value":2655,"currency":"USD","value_usd":2655},"apc_paid":{"value":2655,"currency":"USD","value_usd":2655},"fwci":0.5887,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.64466358,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"18","issue":"11","first_page":"e1010111","last_page":"e1010111"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10982","display_name":"Motor Control and Adaptation","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10982","display_name":"Motor Control and Adaptation","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mechanism","display_name":"Mechanism (biology)","score":0.8021227121353149},{"id":"https://openalex.org/keywords/neurotypical","display_name":"Neurotypical","score":0.7728933095932007},{"id":"https://openalex.org/keywords/action-selection","display_name":"Action selection","score":0.6682295799255371},{"id":"https://openalex.org/keywords/action","display_name":"Action (physics)","score":0.6576026082038879},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6528196334838867},{"id":"https://openalex.org/keywords/flexibility","display_name":"Flexibility (engineering)","score":0.5627564191818237},{"id":"https://openalex.org/keywords/parkinsons-disease","display_name":"Parkinson's disease","score":0.48939481377601624},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.4399268627166748},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.4397995173931122},{"id":"https://openalex.org/keywords/cognitive-psychology","display_name":"Cognitive psychology","score":0.4278773367404938},{"id":"https://openalex.org/keywords/mechanism-of-action","display_name":"Mechanism of action","score":0.42433303594589233},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.28112685680389404},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.17862406373023987},{"id":"https://openalex.org/keywords/developmental-psychology","display_name":"Developmental psychology","score":0.1601448953151703},{"id":"https://openalex.org/keywords/economics","display_name":"Economics","score":0.09011799097061157},{"id":"https://openalex.org/keywords/autism","display_name":"Autism","score":0.08845242857933044}],"concepts":[{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.8021227121353149},{"id":"https://openalex.org/C2778391849","wikidata":"https://www.wikidata.org/wiki/Q1079090","display_name":"Neurotypical","level":4,"score":0.7728933095932007},{"id":"https://openalex.org/C166109690","wikidata":"https://www.wikidata.org/wiki/Q4677422","display_name":"Action selection","level":3,"score":0.6682295799255371},{"id":"https://openalex.org/C2780791683","wikidata":"https://www.wikidata.org/wiki/Q846785","display_name":"Action (physics)","level":2,"score":0.6576026082038879},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6528196334838867},{"id":"https://openalex.org/C2780598303","wikidata":"https://www.wikidata.org/wiki/Q65921492","display_name":"Flexibility (engineering)","level":2,"score":0.5627564191818237},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.48939481377601624},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4399268627166748},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4397995173931122},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.4278773367404938},{"id":"https://openalex.org/C2776120743","wikidata":"https://www.wikidata.org/wiki/Q3271540","display_name":"Mechanism of action","level":3,"score":0.42433303594589233},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28112685680389404},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17862406373023987},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.1601448953151703},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.09011799097061157},{"id":"https://openalex.org/C205778803","wikidata":"https://www.wikidata.org/wiki/Q38404","display_name":"Autism","level":2,"score":0.08845242857933044},{"id":"https://openalex.org/C187736073","wikidata":"https://www.wikidata.org/wiki/Q2920921","display_name":"Management","level":1,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C2778538070","wikidata":"https://www.wikidata.org/wiki/Q1436063","display_name":"Autism spectrum disorder","level":3,"score":0.0},{"id":"https://openalex.org/C26760741","wikidata":"https://www.wikidata.org/wiki/Q160402","display_name":"Perception","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007266","descriptor_name":"Inhibition, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007266","descriptor_name":"Inhibition, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007266","descriptor_name":"Inhibition, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011930","descriptor_name":"Reaction Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011930","descriptor_name":"Reaction Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011930","descriptor_name":"Reaction Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032921","descriptor_name":"Consensus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032921","descriptor_name":"Consensus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032921","descriptor_name":"Consensus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1371/journal.pcbi.1010111","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010111","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010111&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},{"id":"pmid:36395336","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36395336","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":null},{"id":"pmh:oai:doaj.org/article:355d80b805a145d4a222ad690fd2c05c","is_oa":true,"landing_page_url":"https://doaj.org/article/355d80b805a145d4a222ad690fd2c05c","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 18, Iss 11, p e1010111 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9714880","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9714880","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1010111","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1010111","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1010111&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7099999785423279,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G1105927947","display_name":null,"funder_award_id":"R01NS097782","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3047474523","display_name":null,"funder_award_id":"U01NS098961","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G4621706763","display_name":null,"funder_award_id":"U01NS098961","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7605602587","display_name":null,"funder_award_id":"R01NS097782","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4309231816.pdf","grobid_xml":"https://content.openalex.org/works/W4309231816.grobid-xml"},"referenced_works_count":113,"referenced_works":["https://openalex.org/W1440913109","https://openalex.org/W1581687459","https://openalex.org/W1766116129","https://openalex.org/W1950480260","https://openalex.org/W1970951996","https://openalex.org/W1972903903","https://openalex.org/W1973578688","https://openalex.org/W1977503502","https://openalex.org/W1977580164","https://openalex.org/W1978956894","https://openalex.org/W1985321315","https://openalex.org/W1987830056","https://openalex.org/W1988607021","https://openalex.org/W1993631201","https://openalex.org/W2001488773","https://openalex.org/W2004224388","https://openalex.org/W2006414608","https://openalex.org/W2007521850","https://openalex.org/W2010606350","https://openalex.org/W2012524953","https://openalex.org/W2015532569","https://openalex.org/W2016527110","https://openalex.org/W2018177931","https://openalex.org/W2019371219","https://openalex.org/W2028406153","https://openalex.org/W2029374312","https://openalex.org/W2032423882","https://openalex.org/W2032983381","https://openalex.org/W2033002906","https://openalex.org/W2039382055","https://openalex.org/W2039729702","https://openalex.org/W2039858203","https://openalex.org/W2044604553","https://openalex.org/W2055473086","https://openalex.org/W2058317558","https://openalex.org/W2058635102","https://openalex.org/W2060554783","https://openalex.org/W2063887995","https://openalex.org/W2064885604","https://openalex.org/W2066931620","https://openalex.org/W2068640258","https://openalex.org/W2069166530","https://openalex.org/W2072646528","https://openalex.org/W2073690417","https://openalex.org/W2080119716","https://openalex.org/W2085555115","https://openalex.org/W2086590191","https://openalex.org/W2088495343","https://openalex.org/W2089030269","https://openalex.org/W2092349579","https://openalex.org/W2095401753","https://openalex.org/W2096452841","https://openalex.org/W2101518352","https://openalex.org/W2101576232","https://openalex.org/W2103223548","https://openalex.org/W2104822204","https://openalex.org/W2107632774","https://openalex.org/W2108473514","https://openalex.org/W2108599940","https://openalex.org/W2109495498","https://openalex.org/W2110830643","https://openalex.org/W2111853573","https://openalex.org/W2116257195","https://openalex.org/W2118125647","https://openalex.org/W2118907350","https://openalex.org/W2124906793","https://openalex.org/W2130290611","https://openalex.org/W2132317236","https://openalex.org/W2135841994","https://openalex.org/W2140222892","https://openalex.org/W2140309190","https://openalex.org/W2140495951","https://openalex.org/W2148800933","https://openalex.org/W2149002102","https://openalex.org/W2150194358","https://openalex.org/W2150380514","https://openalex.org/W2150431368","https://openalex.org/W2150819471","https://openalex.org/W2152343703","https://openalex.org/W2156743548","https://openalex.org/W2157659716","https://openalex.org/W2159460345","https://openalex.org/W2168725723","https://openalex.org/W2168899895","https://openalex.org/W2171848154","https://openalex.org/W2176873872","https://openalex.org/W2221244967","https://openalex.org/W2239228331","https://openalex.org/W2298599036","https://openalex.org/W2312617909","https://openalex.org/W2341482721","https://openalex.org/W2346488002","https://openalex.org/W2523196466","https://openalex.org/W2523646673","https://openalex.org/W2561246600","https://openalex.org/W2593493261","https://openalex.org/W2600141590","https://openalex.org/W2615908211","https://openalex.org/W2751755304","https://openalex.org/W2755293500","https://openalex.org/W2886189758","https://openalex.org/W2897499013","https://openalex.org/W2922319342","https://openalex.org/W2941937232","https://openalex.org/W2952816932","https://openalex.org/W3198725949","https://openalex.org/W3202610584","https://openalex.org/W3209749458","https://openalex.org/W4213459747","https://openalex.org/W4234802248","https://openalex.org/W4249292264","https://openalex.org/W4251300348","https://openalex.org/W6654550947"],"related_works":["https://openalex.org/W2175842555","https://openalex.org/W2017576287","https://openalex.org/W4403215564","https://openalex.org/W3015907530","https://openalex.org/W3126604710","https://openalex.org/W2895760658","https://openalex.org/W2922100205","https://openalex.org/W4387598408","https://openalex.org/W3015872025","https://openalex.org/W4311735205"],"abstract_inverted_index":{"Surviving":[0],"in":[1,37,123,133,139,154,207],"an":[2,162,176],"uncertain":[3],"environment":[4],"requires":[5],"not":[6],"only":[7],"the":[8,12,17,24,49,68,77,102,130,155],"ability":[9],"to":[10,19,90,120,199],"select":[11],"best":[13],"action,":[14],"but":[15],"also":[16],"flexibility":[18],"withhold":[20],"inappropriate":[21],"actions":[22,32],"when":[23,165],"environmental":[25],"conditions":[26],"change.":[27],"Although":[28],"selecting":[29],"and":[30,40,56,111,136,160,173,187,203],"withholding":[31],"have":[33],"been":[34],"extensively":[35],"studied":[36],"both":[38,184],"human":[39],"animals,":[41],"there":[42],"is":[43,67,169,192,196],"still":[44],"lack":[45,69],"of":[46,70,79,104,115,157,179],"consensus":[47],"on":[48],"mechanism":[50,103,117,178,191],"underlying":[51],"these":[52],"action":[53,80,105,146,152,164,180,185,208],"regulation":[54,81,106,181],"functions,":[55],"more":[57],"importantly,":[58],"how":[59,113],"they":[60],"inter-relate.":[61],"A":[62],"critical":[63],"gap":[64],"impeding":[65],"progress":[66],"a":[71,83,96,166],"computational":[72,98],"theory":[73,99,174],"that":[74,100,107,143,182],"will":[75],"integrate":[76],"mechanisms":[78],"into":[82],"unified":[84],"framework.":[85],"The":[86],"current":[87],"study":[88],"aims":[89],"advance":[91],"our":[92],"understanding":[93],"by":[94],"developing":[95],"neurodynamical":[97],"models":[101],"involves":[108],"suppressing":[109],"responses,":[110],"predicts":[112],"disruption":[114],"this":[116,190],"can":[118],"lead":[119],"motor":[121,194],"deficits":[122],"Parkinson's":[124],"disease":[125],"(PD)":[126],"patients.":[127],"We":[128],"tested":[129],"model":[131],"predictions":[132],"neurotypical":[134],"individuals":[135],"PD":[137],"patients":[138],"three":[140],"behavioral":[141],"tasks":[142],"involve":[144],"free":[145],"selection":[147,153],"between":[148],"two":[149],"opposed":[150],"directions,":[151],"presence":[156],"conflicting":[158],"information":[159],"abandoning":[161],"ongoing":[163],"stop":[167],"signal":[168],"presented.":[170],"Our":[171],"results":[172],"suggest":[175],"integrated":[177],"affects":[183],"initiation":[186],"inhibition.":[188,209],"When":[189],"disrupted,":[193],"behavior":[195],"affected,":[197],"leading":[198],"longer":[200],"reaction":[201],"times":[202],"higher":[204],"error":[205],"rates":[206]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}
